2POMA

Tab1 with manganese ion
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
355
structure length
355
Chain Sequence
SWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein/metal binding protein
source organism Homo sapiens
publication title XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.
pubmed doi rcsb
molecule keywords Mitogen-activated protein kinase kinase kinase 7-interacting
total genus 114
structure length 355
sequence length 355
ec nomenclature
pdb deposition date 2007-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00481 PP2C Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2pomA00
3UJGB 3UJLB 3W42A 4YZHA 5D2UA 2P8EA 3QN1B 4DA1A 4OICB 2I44A 3NMVB 3FXKA 3FXMA 3F79A 3NMTB 3JRQA 3W45A 4RA2A 3N3CA 2Y09A 3EQ2A 3UJKA 3RNRA 3W40A 4LG5B 1A6QA 2JFRA 3D8KA 4JNDA 5F1MA 2XZVA 3T9QA 5JO2B 5JO1B 2J4OA 5ITIA 3FXLA 4LA7B 3ZT9A 2PNQA 4WVOB 3RT0A 4N0GA 3MQ3A 2IRMA 4LGBB 3ES2A 2PK0A 2I0OA 3KB3B 2JFSA 3W41A 2ISNA 3T91A 4RAGA 2POMA 4DS8B 4LGAB 3FXOA 2POPA 2V06A 2J86A 2IQ1A 3NMNB 2J82A 3ZVUB 1TXOA 3W44A 4YZGA 2JFTA 2CM1A 3FXJA 3KE6A 3KDJB 3W43A 3PU9A 4RAFA
chains in the Genus database with same CATH superfamily
3UJGB 3UJLB 3W42A 4YZHA 5D2UA 2P8EA 3QN1B 4DA1A 4OICB 2I44A 3NMVB 3FXKA 3FXMA 3F79A 3NMTB 3JRQA 3W45A 4RA2A 3N3CA 2Y09A 3EQ2A 3UJKA 3RNRA 3W40A 4LG5B 1A6QA 2JFRA 3D8KA 4JNDA 5F1MA 2XZVA 3T9QA 5JO2B 5JO1B 2J4OA 5ITIA 3FXLA 4LA7B 3ZT9A 2PNQA 4WVOB 3RT0A 4N0GA 3MQ3A 2IRMA 4LGBB 3ES2A 2PK0A 2I0OA 3KB3B 2JFSA 3W41A 2ISNA 3T91A 4RAGA 2POMA 4DS8B 4LGAB 3FXOA 2POPA 2V06A 2J86A 4IIPA 4IIKA 2IQ1A 3NMNB 2J82A 3ZVUB 1TXOA 3W44A 4YZGA 2JFTA 2CM1A 3FXJA 3KE6A 3KDJB 3W43A 3PU9A 4RAFA
chains in the Genus database with same CATH topology
3UJGB 3UJLB 3W42A 4YZHA 5D2UA 2P8EA 3QN1B 4DA1A 4OICB 2I44A 3NMVB 3FXKA 3FXMA 3F79A 3NMTB 3JRQA 3W45A 4RA2A 3N3CA 2Y09A 3EQ2A 3UJKA 3RNRA 3W40A 4LG5B 1A6QA 2JFRA 3D8KA 4JNDA 5F1MA 2XZVA 3T9QA 5JO2B 5JO1B 2J4OA 5ITIA 3FXLA 4LA7B 3ZT9A 2PNQA 4WVOB 3RT0A 4N0GA 3MQ3A 2IRMA 4LGBB 3ES2A 2PK0A 2I0OA 3KB3B 2JFSA 3W41A 2ISNA 3T91A 4RAGA 2POMA 4DS8B 4LGAB 3FXOA 2POPA 2V06A 2J86A 2IQ1A 3NMNB 2J82A 3ZVUB 1TXOA 3W44A 4YZGA 2JFTA 2CM1A 3FXJA 3KE6A 3KDJB 3W43A 3PU9A 4RAFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3UJG B;  3UJL B;  3W42 A;  4YZH A;  5D2U A;  2P8E A;  3QN1 B;  4DA1 A;  4OIC B;  2I44 A;  3NMV B;  3FXK A;  3FXM A;  3F79 A;  3NMT B;  3JRQ A;  3W45 A;  4RA2 A;  3N3C A;  2Y09 A;  3EQ2 A;  3UJK A;  3RNR A;  3W40 A;  4LG5 B;  1A6Q A;  2JFR A;  3D8K A;  4JND A;  5F1M A;  2XZV A;  3T9Q A;  5JO2 B;  5JO1 B;  2J4O A;  5ITI A;  3FXL A;  4LA7 B;  3ZT9 A;  2PNQ A;  4WVO B;  3RT0 A;  4N0G A;  3MQ3 A;  2IRM A;  4LGB B;  3ES2 A;  2PK0 A;  2I0O A;  3KB3 B;  2JFS A;  3W41 A;  2ISN A;  3T91 A;  4RAG A;  2POM A;  4DS8 B;  4LGA B;  3FXO A;  2POP A;  2V06 A;  2J86 A;  2IQ1 A;  3NMN B;  2J82 A;  3ZVU B;  1TXO A;  3W44 A;  4YZG A;  2JFT A;  2CM1 A;  3FXJ A;  3KE6 A;  3KDJ B;  3W43 A;  3PU9 A;  4RAF A; 
#chains in the Genus database with same CATH topology
 3UJG B;  3UJL B;  3W42 A;  4YZH A;  5D2U A;  2P8E A;  3QN1 B;  4DA1 A;  4OIC B;  2I44 A;  3NMV B;  3FXK A;  3FXM A;  3F79 A;  3NMT B;  3JRQ A;  3W45 A;  4RA2 A;  3N3C A;  2Y09 A;  3EQ2 A;  3UJK A;  3RNR A;  3W40 A;  4LG5 B;  1A6Q A;  2JFR A;  3D8K A;  4JND A;  5F1M A;  2XZV A;  3T9Q A;  5JO2 B;  5JO1 B;  2J4O A;  5ITI A;  3FXL A;  4LA7 B;  3ZT9 A;  2PNQ A;  4WVO B;  3RT0 A;  4N0G A;  3MQ3 A;  2IRM A;  4LGB B;  3ES2 A;  2PK0 A;  2I0O A;  3KB3 B;  2JFS A;  3W41 A;  2ISN A;  3T91 A;  4RAG A;  2POM A;  4DS8 B;  4LGA B;  3FXO A;  2POP A;  2V06 A;  2J86 A;  4IIP A;  4IIK A;  2IQ1 A;  3NMN B;  2J82 A;  3ZVU B;  1TXO A;  3W44 A;  4YZG A;  2JFT A;  2CM1 A;  3FXJ A;  3KE6 A;  3KDJ B;  3W43 A;  3PU9 A;  4RAF A; 
#chains in the Genus database with same CATH homology
 3UJG B;  3UJL B;  3W42 A;  4YZH A;  5D2U A;  2P8E A;  3QN1 B;  4DA1 A;  4OIC B;  2I44 A;  3NMV B;  3FXK A;  3FXM A;  3F79 A;  3NMT B;  3JRQ A;  3W45 A;  4RA2 A;  3N3C A;  2Y09 A;  3EQ2 A;  3UJK A;  3RNR A;  3W40 A;  4LG5 B;  1A6Q A;  2JFR A;  3D8K A;  4JND A;  5F1M A;  2XZV A;  3T9Q A;  5JO2 B;  5JO1 B;  2J4O A;  5ITI A;  3FXL A;  4LA7 B;  3ZT9 A;  2PNQ A;  4WVO B;  3RT0 A;  4N0G A;  3MQ3 A;  2IRM A;  4LGB B;  3ES2 A;  2PK0 A;  2I0O A;  3KB3 B;  2JFS A;  3W41 A;  2ISN A;  3T91 A;  4RAG A;  2POM A;  4DS8 B;  4LGA B;  3FXO A;  2POP A;  2V06 A;  2J86 A;  2IQ1 A;  3NMN B;  2J82 A;  3ZVU B;  1TXO A;  3W44 A;  4YZG A;  2JFT A;  2CM1 A;  3FXJ A;  3KE6 A;  3KDJ B;  3W43 A;  3PU9 A;  4RAF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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