2POPA

The crystal structure of tab1 and bir1 complex
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
334
structure length
326
Chain Sequence
TDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDQLERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.
pubmed doi rcsb
molecule tags Signaling protein/apoptosis
source organism Homo sapiens
molecule keywords Mitogen-activated protein kinase kinase kinase 7-interacting
total genus 83
structure length 326
sequence length 334
chains with identical sequence C
ec nomenclature
pdb deposition date 2007-04-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00481 PP2C Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2popA00
2V06A 4LG5B 3FXLA 2I0OA 2P8EA 3ES2A 3EQ2A 3W43A 3FXKA 3W42A 3T91A 4DS8B 2JFSA 3KB3B 3W40A 4DA1A 2JFTA 3UJKA 1TXOA 2J86A 2IQ1A 2PK0A 3KDJB 3NMTB 2J82A 4LA7B 2PNQA 4RAFA 3FXMA 4LGAB 4RAGA 5JO2B 3W45A 2XZVA 5F1MA 3F79A 3UJLB 2I44A 3W44A 2J4OA 3FXJA 4WVOB 3D8KA 3KE6A 4N0GA 4YZGA 3ZT9A 2CM1A 2POPA 3W41A 3FXOA 4JNDA 3ZVUB 5ITIA 3UJGB 3NMNB 2IRMA 4LGBB 3PU9A 4RA2A 5D2UA 5JO1B 4OICB 3T9QA 2ISNA 2POMA 2JFRA 3RT0A 1A6QA 4YZHA 3MQ3A 2Y09A 3RNRA 3JRQA 3NMVB 3N3CA 3QN1B
chains in the Genus database with same CATH superfamily
2V06A 4LG5B 3FXLA 2I0OA 2P8EA 3ES2A 3EQ2A 3W43A 3FXKA 3W42A 4IIKA 3T91A 4DS8B 2JFSA 3KB3B 3W40A 4DA1A 2JFTA 3UJKA 1TXOA 2J86A 2IQ1A 2PK0A 3KDJB 3NMTB 2J82A 4LA7B 2PNQA 4RAFA 3FXMA 4LGAB 4RAGA 5JO2B 3W45A 2XZVA 5F1MA 3F79A 3UJLB 2I44A 3W44A 4IIPA 2J4OA 3FXJA 4WVOB 3D8KA 3KE6A 4N0GA 4YZGA 3ZT9A 2CM1A 2POPA 3W41A 3FXOA 4JNDA 3ZVUB 5ITIA 3UJGB 3NMNB 2IRMA 4LGBB 3PU9A 4RA2A 5D2UA 5JO1B 4OICB 3T9QA 2ISNA 2POMA 2JFRA 3RT0A 1A6QA 4YZHA 3MQ3A 2Y09A 3RNRA 3JRQA 3NMVB 3N3CA 3QN1B
chains in the Genus database with same CATH topology
2V06A 4LG5B 3FXLA 2I0OA 2P8EA 3ES2A 3EQ2A 3W43A 3FXKA 3W42A 3T91A 4DS8B 2JFSA 3KB3B 3W40A 4DA1A 2JFTA 3UJKA 1TXOA 2J86A 2IQ1A 2PK0A 3KDJB 3NMTB 2J82A 4LA7B 2PNQA 4RAFA 3FXMA 4LGAB 4RAGA 5JO2B 3W45A 2XZVA 5F1MA 3F79A 3UJLB 2I44A 3W44A 2J4OA 3FXJA 4WVOB 3D8KA 3KE6A 4N0GA 4YZGA 3ZT9A 2CM1A 2POPA 3W41A 3FXOA 4JNDA 3ZVUB 5ITIA 3UJGB 3NMNB 2IRMA 4LGBB 3PU9A 4RA2A 5D2UA 5JO1B 4OICB 3T9QA 2ISNA 2POMA 2JFRA 3RT0A 1A6QA 4YZHA 3MQ3A 2Y09A 3RNRA 3JRQA 3NMVB 3N3CA 3QN1B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V06 A;  4LG5 B;  3FXL A;  2I0O A;  2P8E A;  3ES2 A;  3EQ2 A;  3W43 A;  3FXK A;  3W42 A;  3T91 A;  4DS8 B;  2JFS A;  3KB3 B;  3W40 A;  4DA1 A;  2JFT A;  3UJK A;  1TXO A;  2J86 A;  2IQ1 A;  2PK0 A;  3KDJ B;  3NMT B;  2J82 A;  4LA7 B;  2PNQ A;  4RAF A;  3FXM A;  4LGA B;  4RAG A;  5JO2 B;  3W45 A;  2XZV A;  5F1M A;  3F79 A;  3UJL B;  2I44 A;  3W44 A;  2J4O A;  3FXJ A;  4WVO B;  3D8K A;  3KE6 A;  4N0G A;  4YZG A;  3ZT9 A;  2CM1 A;  2POP A;  3W41 A;  3FXO A;  4JND A;  3ZVU B;  5ITI A;  3UJG B;  3NMN B;  2IRM A;  4LGB B;  3PU9 A;  4RA2 A;  5D2U A;  5JO1 B;  4OIC B;  3T9Q A;  2ISN A;  2POM A;  2JFR A;  3RT0 A;  1A6Q A;  4YZH A;  3MQ3 A;  2Y09 A;  3RNR A;  3JRQ A;  3NMV B;  3N3C A;  3QN1 B; 
#chains in the Genus database with same CATH topology
 2V06 A;  4LG5 B;  3FXL A;  2I0O A;  2P8E A;  3ES2 A;  3EQ2 A;  3W43 A;  3FXK A;  3W42 A;  4IIK A;  3T91 A;  4DS8 B;  2JFS A;  3KB3 B;  3W40 A;  4DA1 A;  2JFT A;  3UJK A;  1TXO A;  2J86 A;  2IQ1 A;  2PK0 A;  3KDJ B;  3NMT B;  2J82 A;  4LA7 B;  2PNQ A;  4RAF A;  3FXM A;  4LGA B;  4RAG A;  5JO2 B;  3W45 A;  2XZV A;  5F1M A;  3F79 A;  3UJL B;  2I44 A;  3W44 A;  4IIP A;  2J4O A;  3FXJ A;  4WVO B;  3D8K A;  3KE6 A;  4N0G A;  4YZG A;  3ZT9 A;  2CM1 A;  2POP A;  3W41 A;  3FXO A;  4JND A;  3ZVU B;  5ITI A;  3UJG B;  3NMN B;  2IRM A;  4LGB B;  3PU9 A;  4RA2 A;  5D2U A;  5JO1 B;  4OIC B;  3T9Q A;  2ISN A;  2POM A;  2JFR A;  3RT0 A;  1A6Q A;  4YZH A;  3MQ3 A;  2Y09 A;  3RNR A;  3JRQ A;  3NMV B;  3N3C A;  3QN1 B; 
#chains in the Genus database with same CATH homology
 2V06 A;  4LG5 B;  3FXL A;  2I0O A;  2P8E A;  3ES2 A;  3EQ2 A;  3W43 A;  3FXK A;  3W42 A;  3T91 A;  4DS8 B;  2JFS A;  3KB3 B;  3W40 A;  4DA1 A;  2JFT A;  3UJK A;  1TXO A;  2J86 A;  2IQ1 A;  2PK0 A;  3KDJ B;  3NMT B;  2J82 A;  4LA7 B;  2PNQ A;  4RAF A;  3FXM A;  4LGA B;  4RAG A;  5JO2 B;  3W45 A;  2XZV A;  5F1M A;  3F79 A;  3UJL B;  2I44 A;  3W44 A;  2J4O A;  3FXJ A;  4WVO B;  3D8K A;  3KE6 A;  4N0G A;  4YZG A;  3ZT9 A;  2CM1 A;  2POP A;  3W41 A;  3FXO A;  4JND A;  3ZVU B;  5ITI A;  3UJG B;  3NMN B;  2IRM A;  4LGB B;  3PU9 A;  4RA2 A;  5D2U A;  5JO1 B;  4OIC B;  3T9Q A;  2ISN A;  2POM A;  2JFR A;  3RT0 A;  1A6Q A;  4YZH A;  3MQ3 A;  2Y09 A;  3RNR A;  3JRQ A;  3NMV B;  3N3C A;  3QN1 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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