2R7ZF

Cisplatin lesion containing rna polymerase ii elongation complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of transcriptional stalling at cisplatin-damaged DNA.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
molecule keywords 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'
total genus 23
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2007-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 2r7zF00
2PMZK 3S1RF 4C3IF 2JA6F 4BY1F 5IP9F 2PPBE 5M5WF 2B63F 2JA7F 4KMUE 4XSZE 1ZYRE 4OIOE 4OINE 1Y1WF 1I3QF 2NVXF 3S2HF 4LK1E 3S15F 2A6EE 3M4OF 5M5YF 4XLPE 1YNNK 3PO3F 4C3HF 5TMCE 3GTJF 4G7HE 4JK1E 1TWFF 4YFKE 5M3FF 3DXJE 4Q4ZE 4A3MF 4BXXF 4A3EF 2JA5F 2WB1I 1WCMF 2E2IF 2A6HE 4C2MF 4X6AF 4A3JF 2E2HF 1TWHF 3S1NF 4OIQE 1I6VE 2R93F 3EQLE 3HOYF 2O5IE 1I6HF 3GTLF 3GTOF 3I4MF 3HOUF 4G7ZE 5D4CE 4A93F 5FLMF 2R92F 4YFNE 2WAQK 5M5XF 3HOZF 3RZOF 4YG2E 5D4DE 5C4XF 5E17E 5BYHE 5TMFE 5M3MF 2JA8F 2NVYF 1R9TF 2O5JE 4ZH4E 2VUMF 2BE5E 3GTMF 4C3JF 3S1QF 4Y7NF 3WODE 1SFOF 4BBRF 3RZDF 4A3DF 1TWAF 5IPLE 3S17F 3HOVF 4KN4E 4Y52F 1SMYE 3M3YF 1QKLA 1I50F 2NVQF 4LJZE 3CQZF 5D4EE 5IP7F 3GTGF 3H3VG 4A3IF 3GTPF 3S1MF 2CW0E 2R7ZF 4GZYE 5IYDF 5C44F 3H0GF 3I4NF 3GTKF 3HOWF 1K83F 5IYCF 3S14F 5FJ8F 4KN7E 1Y1VF 1IW7E 2A69E 3HKZK 4A3GF 4G7OE 4XLNE 3S2DF 4A3CF 4Q5SE 4LLGE 5E18E 4AYBK 1TWCF 4MEYE 5C3EF 4BBSF 3HOXF 4A3KF 4A3FF 1HQME 2NVTF 2A68E 1TWGF 4MQ9E 2E2JF 3K7AF 5C4JF 3S16F 3FKIF 4MEXE 3GTQF 1YNJK 4OIRE 4YFXE 3PO2F 5IYBF 4OIPE 4XSXE 4A3LF 4LK0E 2YU9F 4A3BF 2Y0SI 4BY7F
chains in the Genus database with same CATH superfamily
2PMZK 3HOXE 3S2HE 3S1RF 1DZFA 4C3IF 3M4OE 2JA6F 4BY1F 5M5YE 2NVTE 5IP9F 2E2JE 3K7AE 2PPBE 5M5WF 2B63F 3S16E 2JA7F 4KMUE 4XSZE 3GTJE 3GTQE 1ZYRE 4OIOE 5M3FE 1Y1WF 4OINE 2WAQH 1I3QF 2NVXF 4A3ME 3S2HF 4LK1E 4BXXE 3S15F 2A6EE 2YU9E 3M4OF 4A3BE 5M5YF 2JA5E 4XLPE 1WCME 1YNNK 3PO3F 3S1RE 4C3HF 2E2IE 5TMCE 3GTJF 2JA6E 4G7HE 4JK1E 4C2ME 2B63E 1TWFF 4YFKE 5M3FF 3DXJE 4X6AE 2E2HE 1TWHE 4Q4ZE 4A3MF 4BXXF 1I3QE 4A3EF 3HOYE 2JA5F 1I6HE 2WB1I 1WCMF 3GTLE 2E2IF 3HOUE 3I4ME 3S15E 5FLME 2R92E 2A6HE 3PO3E 4C2MF 4C3HE 5M5XE 3RZOE 3HOZE 4A3JF 4X6AF 2E2HF 1TWHF 3H3VF 5C4XE 2JA8E 2Y0SH 3S1NF 1TWFE 2WB1H 1I6VE 1R9TE 4OIQE 2VUME 3EQLE 3HOYF 2O5IE 1I6HF 3GTME 2R93F 3GTLF 3GTOF 3I4MF 3HOUF 4G7ZE 3S1QE 1SFOE 5D4CE 4BBRE 4A3EE 3RZDE 5FLMF 4A93F 2R92F 4YFNE 2WAQK 5M5XF 3HOZF 3RZOF 1TWAE 4YG2E 5D4DE 5C4XF 5E17E 3HKZH 5BYHE 5TMFE 5M3MF 2JA8F 2NVYF 1R9TF 3S17E 4ZH4E 2VUMF 4A3JE 2BE5E 2O5JE 3GTMF 3HOVE 4Y52E 3S1NE 4C3JF 3S1QF 4Y7NF 2R93E 1I50E 3WODE 1SFOF 4BBRF 3RZDF 2NVQE 3GTOE 3GTGE 4A3DF 1TWAF 4A93E 5IPLE 4QIWH 4A3IE 3GTPE 3S17F 3S1ME 3HOVF 5IYDE 4KN4E 4Y52F 5C44E 3H0GE 5M3ME 1SMYE 3M3YF 2NVYE 3GTKE 1QKLA 1I50F 3HOWE 1K83E 3S14E 2NVQF 4LJZE 4C3JE 3CQZF 5D4EE 5IP7F 4Y7NE 3GTGF 2PMZH 3H3VG 4A3DE 4A3IF 3GTPF 3S1MF 2CW0E 2R7ZF 4A3CE 4GZYE 5IYDF 5C44F 3H0GF 3I4NF 3GTKF 4BBSE 4A3KE 1K83F 5IYCF 4A3FE 3HOWF 3S14F 1EIKA 4AYBH 4KN7E 1Y1VF 5FJ8F 1TWGE 3M3YE 5C4JE 1IW7E 2A69E 3FKIE 3HKZK 4G7OE 4A3GF 4XLNE 3CQZE 5IP7E 3S2DF 4A3CF 4Q5SE 4LLGE 5E18E 4AYBK 3PO2E 5IYBE 1TWCF 4MEYE 5C3EF 2R7ZE 3HOXF 4A3KF 4A3FF 4BBSF 1HQME 4A3LE 2NVTF 2A68E 3I4NE 1TWGF 4MQ9E 4BY7E 2E2JF 3K7AF 5IYCE 5C4JF 3S16F 4C3IE 2KRXA 3FKIF 4QIWK 1Y1VE 1YNJK 5FJ8E 4MEXE 4BY1E 3GTQF 4OIRE 5IP9E 5M5WE 4YFXE 3PO2F 2JA7E 4A3GE 5IYBF 4OIPE 4XSXE 3S2DE 4A3LF 4LK0E 1Y1WE 2YU9F 4A3BF 2NVXE 1TWCE 2Y0SI 4BY7F 5C3EE
chains in the Genus database with same CATH topology
2PMZK 3S1RF 4C3IF 2JA6F 4BY1F 5IP9F 2PPBE 5M5WF 2B63F 2JA7F 4KMUE 4XSZE 1ZYRE 4OIOE 4OINE 1Y1WF 1I3QF 2NVXF 3S2HF 4LK1E 3S15F 2A6EE 3M4OF 5M5YF 4XLPE 1YNNK 3PO3F 4C3HF 5TMCE 3GTJF 4G7HE 4JK1E 1TWFF 4YFKE 5M3FF 3DXJE 4Q4ZE 4A3MF 4BXXF 4A3EF 2JA5F 2WB1I 1WCMF 2E2IF 2A6HE 4C2MF 4X6AF 4A3JF 2E2HF 1TWHF 3S1NF 4OIQE 1I6VE 2R93F 3EQLE 3HOYF 2O5IE 1I6HF 3GTLF 3GTOF 3I4MF 3HOUF 4G7ZE 5D4CE 4A93F 5FLMF 2R92F 4YFNE 2WAQK 5M5XF 3HOZF 3RZOF 4YG2E 5D4DE 5C4XF 5E17E 5BYHE 5TMFE 5M3MF 2JA8F 2NVYF 1R9TF 2O5JE 4ZH4E 2VUMF 2BE5E 3GTMF 4C3JF 3S1QF 4Y7NF 3WODE 1SFOF 4BBRF 3RZDF 4A3DF 1TWAF 5IPLE 3S17F 3HOVF 4KN4E 4Y52F 1SMYE 3M3YF 1QKLA 1I50F 2NVQF 4LJZE 3CQZF 5D4EE 5IP7F 3GTGF 3H3VG 4A3IF 3GTPF 3S1MF 2CW0E 2R7ZF 4GZYE 5IYDF 5C44F 3H0GF 3I4NF 3GTKF 3HOWF 1K83F 5IYCF 3S14F 5FJ8F 4KN7E 1Y1VF 1IW7E 2A69E 3HKZK 4A3GF 4G7OE 4XLNE 3S2DF 4A3CF 4Q5SE 4LLGE 5E18E 4AYBK 1TWCF 4MEYE 5C3EF 4BBSF 3HOXF 4A3KF 4A3FF 1HQME 2NVTF 2A68E 1TWGF 4MQ9E 2E2JF 3K7AF 5C4JF 3S16F 2KRXA 3FKIF 4QIWK 4MEXE 1YNJK 3GTQF 4OIRE 4YFXE 3PO2F 5IYBF 4OIPE 4XSXE 4A3LF 4LK0E 2YU9F 4A3BF 2Y0SI 4BY7F
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2PMZ K;  3S1R F;  4C3I F;  2JA6 F;  4BY1 F;  5IP9 F;  2PPB E;  5M5W F;  2B63 F;  2JA7 F;  4KMU E;  4XSZ E;  1ZYR E;  4OIO E;  4OIN E;  1Y1W F;  1I3Q F;  2NVX F;  3S2H F;  4LK1 E;  3S15 F;  2A6E E;  3M4O F;  5M5Y F;  4XLP E;  1YNN K;  3PO3 F;  4C3H F;  5TMC E;  3GTJ F;  4G7H E;  4JK1 E;  1TWF F;  4YFK E;  5M3F F;  3DXJ E;  4Q4Z E;  4A3M F;  4BXX F;  4A3E F;  2JA5 F;  2WB1 I;  1WCM F;  2E2I F;  2A6H E;  4C2M F;  4X6A F;  4A3J F;  2E2H F;  1TWH F;  3S1N F;  4OIQ E;  1I6V E;  2R93 F;  3EQL E;  3HOY F;  2O5I E;  1I6H F;  3GTL F;  3GTO F;  3I4M F;  3HOU F;  4G7Z E;  5D4C E;  4A93 F;  5FLM F;  2R92 F;  4YFN E;  2WAQ K;  5M5X F;  3HOZ F;  3RZO F;  4YG2 E;  5D4D E;  5C4X F;  5E17 E;  5BYH E;  5TMF E;  5M3M F;  2JA8 F;  2NVY F;  1R9T F;  2O5J E;  4ZH4 E;  2VUM F;  2BE5 E;  3GTM F;  4C3J F;  3S1Q F;  4Y7N F;  3WOD E;  1SFO F;  4BBR F;  3RZD F;  4A3D F;  1TWA F;  5IPL E;  3S17 F;  3HOV F;  4KN4 E;  4Y52 F;  1SMY E;  3M3Y F;  1QKL A;  1I50 F;  2NVQ F;  4LJZ E;  3CQZ F;  5D4E E;  5IP7 F;  3GTG F;  3H3V G;  4A3I F;  3GTP F;  3S1M F;  2CW0 E;  2R7Z F;  4GZY E;  5IYD F;  5C44 F;  3H0G F;  3I4N F;  3GTK F;  3HOW F;  1K83 F;  5IYC F;  3S14 F;  5FJ8 F;  4KN7 E;  1Y1V F;  1IW7 E;  2A69 E;  3HKZ K;  4A3G F;  4G7O E;  4XLN E;  3S2D F;  4A3C F;  4Q5S E;  4LLG E;  5E18 E;  4AYB K;  1TWC F;  4MEY E;  5C3E F;  4BBS F;  3HOX F;  4A3K F;  4A3F F;  1HQM E;  2NVT F;  2A68 E;  1TWG F;  4MQ9 E;  2E2J F;  3K7A F;  5C4J F;  3S16 F;  3FKI F;  4MEX E;  3GTQ F;  1YNJ K;  4OIR E;  4YFX E;  3PO2 F;  5IYB F;  4OIP E;  4XSX E;  4A3L F;  4LK0 E;  2YU9 F;  4A3B F;  2Y0S I;  4BY7 F; 
#chains in the Genus database with same CATH topology
 2PMZ K;  3HOX E;  3S2H E;  3S1R F;  1DZF A;  4C3I F;  3M4O E;  2JA6 F;  4BY1 F;  5M5Y E;  2NVT E;  5IP9 F;  2E2J E;  3K7A E;  2PPB E;  5M5W F;  2B63 F;  3S16 E;  2JA7 F;  4KMU E;  4XSZ E;  3GTJ E;  3GTQ E;  1ZYR E;  4OIO E;  5M3F E;  1Y1W F;  4OIN E;  2WAQ H;  1I3Q F;  2NVX F;  4A3M E;  3S2H F;  4LK1 E;  4BXX E;  3S15 F;  2A6E E;  2YU9 E;  3M4O F;  4A3B E;  5M5Y F;  2JA5 E;  4XLP E;  1WCM E;  1YNN K;  3PO3 F;  3S1R E;  4C3H F;  2E2I E;  5TMC E;  3GTJ F;  2JA6 E;  4G7H E;  4JK1 E;  4C2M E;  2B63 E;  1TWF F;  4YFK E;  5M3F F;  3DXJ E;  4X6A E;  2E2H E;  1TWH E;  4Q4Z E;  4A3M F;  4BXX F;  1I3Q E;  4A3E F;  3HOY E;  2JA5 F;  1I6H E;  2WB1 I;  1WCM F;  3GTL E;  2E2I F;  3HOU E;  3I4M E;  3S15 E;  5FLM E;  2R92 E;  2A6H E;  3PO3 E;  4C2M F;  4C3H E;  5M5X E;  3RZO E;  3HOZ E;  4A3J F;  4X6A F;  2E2H F;  1TWH F;  3H3V F;  5C4X E;  2JA8 E;  2Y0S H;  3S1N F;  1TWF E;  2WB1 H;  1I6V E;  1R9T E;  4OIQ E;  2VUM E;  3EQL E;  3HOY F;  2O5I E;  1I6H F;  3GTM E;  2R93 F;  3GTL F;  3GTO F;  3I4M F;  3HOU F;  4G7Z E;  3S1Q E;  1SFO E;  5D4C E;  4BBR E;  4A3E E;  3RZD E;  5FLM F;  4A93 F;  2R92 F;  4YFN E;  2WAQ K;  5M5X F;  3HOZ F;  3RZO F;  1TWA E;  4YG2 E;  5D4D E;  5C4X F;  5E17 E;  3HKZ H;  5BYH E;  5TMF E;  5M3M F;  2JA8 F;  2NVY F;  1R9T F;  3S17 E;  4ZH4 E;  2VUM F;  4A3J E;  2BE5 E;  2O5J E;  3GTM F;  3HOV E;  4Y52 E;  3S1N E;  4C3J F;  3S1Q F;  4Y7N F;  2R93 E;  1I50 E;  3WOD E;  1SFO F;  4BBR F;  3RZD F;  2NVQ E;  3GTO E;  3GTG E;  4A3D F;  1TWA F;  4A93 E;  5IPL E;  4QIW H;  4A3I E;  3GTP E;  3S17 F;  3S1M E;  3HOV F;  5IYD E;  4KN4 E;  4Y52 F;  5C44 E;  3H0G E;  5M3M E;  1SMY E;  3M3Y F;  2NVY E;  3GTK E;  1QKL A;  1I50 F;  3HOW E;  1K83 E;  3S14 E;  2NVQ F;  4LJZ E;  4C3J E;  3CQZ F;  5D4E E;  5IP7 F;  4Y7N E;  3GTG F;  2PMZ H;  3H3V G;  4A3D E;  4A3I F;  3GTP F;  3S1M F;  2CW0 E;  2R7Z F;  4A3C E;  4GZY E;  5IYD F;  5C44 F;  3H0G F;  3I4N F;  3GTK F;  4BBS E;  4A3K E;  1K83 F;  5IYC F;  4A3F E;  3HOW F;  3S14 F;  1EIK A;  4AYB H;  4KN7 E;  1Y1V F;  5FJ8 F;  1TWG E;  3M3Y E;  5C4J E;  1IW7 E;  2A69 E;  3FKI E;  3HKZ K;  4G7O E;  4A3G F;  4XLN E;  3CQZ E;  5IP7 E;  3S2D F;  4A3C F;  4Q5S E;  4LLG E;  5E18 E;  4AYB K;  3PO2 E;  5IYB E;  1TWC F;  4MEY E;  5C3E F;  2R7Z E;  3HOX F;  4A3K F;  4A3F F;  4BBS F;  1HQM E;  4A3L E;  2NVT F;  2A68 E;  3I4N E;  1TWG F;  4MQ9 E;  4BY7 E;  2E2J F;  3K7A F;  5IYC E;  5C4J F;  3S16 F;  4C3I E;  2KRX A;  3FKI F;  4QIW K;  1Y1V E;  1YNJ K;  5FJ8 E;  4MEX E;  4BY1 E;  3GTQ F;  4OIR E;  5IP9 E;  5M5W E;  4YFX E;  3PO2 F;  2JA7 E;  4A3G E;  5IYB F;  4OIP E;  4XSX E;  3S2D E;  4A3L F;  4LK0 E;  1Y1W E;  2YU9 F;  4A3B F;  2NVX E;  1TWC E;  2Y0S I;  4BY7 F;  5C3E E; 
#chains in the Genus database with same CATH homology
 2PMZ K;  3S1R F;  4C3I F;  2JA6 F;  4BY1 F;  5IP9 F;  2PPB E;  5M5W F;  2B63 F;  2JA7 F;  4KMU E;  4XSZ E;  1ZYR E;  4OIO E;  4OIN E;  1Y1W F;  1I3Q F;  2NVX F;  3S2H F;  4LK1 E;  3S15 F;  2A6E E;  3M4O F;  5M5Y F;  4XLP E;  1YNN K;  3PO3 F;  4C3H F;  5TMC E;  3GTJ F;  4G7H E;  4JK1 E;  1TWF F;  4YFK E;  5M3F F;  3DXJ E;  4Q4Z E;  4A3M F;  4BXX F;  4A3E F;  2JA5 F;  2WB1 I;  1WCM F;  2E2I F;  2A6H E;  4C2M F;  4X6A F;  4A3J F;  2E2H F;  1TWH F;  3S1N F;  4OIQ E;  1I6V E;  2R93 F;  3EQL E;  3HOY F;  2O5I E;  1I6H F;  3GTL F;  3GTO F;  3I4M F;  3HOU F;  4G7Z E;  5D4C E;  4A93 F;  5FLM F;  2R92 F;  4YFN E;  2WAQ K;  5M5X F;  3HOZ F;  3RZO F;  4YG2 E;  5D4D E;  5C4X F;  5E17 E;  5BYH E;  5TMF E;  5M3M F;  2JA8 F;  2NVY F;  1R9T F;  2O5J E;  4ZH4 E;  2VUM F;  2BE5 E;  3GTM F;  4C3J F;  3S1Q F;  4Y7N F;  3WOD E;  1SFO F;  4BBR F;  3RZD F;  4A3D F;  1TWA F;  5IPL E;  3S17 F;  3HOV F;  4KN4 E;  4Y52 F;  1SMY E;  3M3Y F;  1QKL A;  1I50 F;  2NVQ F;  4LJZ E;  3CQZ F;  5D4E E;  5IP7 F;  3GTG F;  3H3V G;  4A3I F;  3GTP F;  3S1M F;  2CW0 E;  2R7Z F;  4GZY E;  5IYD F;  5C44 F;  3H0G F;  3I4N F;  3GTK F;  3HOW F;  1K83 F;  5IYC F;  3S14 F;  5FJ8 F;  4KN7 E;  1Y1V F;  1IW7 E;  2A69 E;  3HKZ K;  4A3G F;  4G7O E;  4XLN E;  3S2D F;  4A3C F;  4Q5S E;  4LLG E;  5E18 E;  4AYB K;  1TWC F;  4MEY E;  5C3E F;  4BBS F;  3HOX F;  4A3K F;  4A3F F;  1HQM E;  2NVT F;  2A68 E;  1TWG F;  4MQ9 E;  2E2J F;  3K7A F;  5C4J F;  3S16 F;  2KRX A;  3FKI F;  4QIW K;  4MEX E;  1YNJ K;  3GTQ F;  4OIR E;  4YFX E;  3PO2 F;  5IYB F;  4OIP E;  4XSX E;  4A3L F;  4LK0 E;  2YU9 F;  4A3B F;  2Y0S I;  4BY7 F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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