2W1VA

Crystal structure of mouse nitrilase-2 at 1.4a resolution
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
274
structure length
274
Chain Sequence
MSTFRLALIQLQVSSIKSDNLTRACSLVREAAKQGANIVSLPECFNSPYGTTYFPDYAEKIPGESTQKLSEVAKESSIYLIGGSIPEEDAGKLYNTCSVFGPDGSLLVKHRKIHLFDIDVPGKITFQESKTLSPGDSFSTFDTPYCKVGLGICYDMRFAELAQIYAQRGCQLLVYPGAFNLTTGPAHWELLQRARAVDNQVYVATASPARDDKASYVAWGHSTVVDPWGQVLTKAGTEETILYSDIDLKKLAEIRQQIPILKQKRADLYTVESK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Functional Proteomic and Structural Insights Into Molecular Recognition in the Nitrilase Family Enzymes.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mus musculus
molecule keywords NITRILASE HOMOLOG 2
total genus 86
structure length 274
sequence length 274
chains with identical sequence B
ec nomenclature ec 3.5.1.3: Omega-amidase.
pdb deposition date 2008-10-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 2w1vA00
2GGLA 3KI8A 4F4HA 1ERZA 3P8KA 4IZVA 4CYGA 3IW3A 5H8JA 4KZFA 2GGKA 4GYNA 5H8KA 4GYLA 1EMSA 5KHAA 3SDBA 4IZSA 2E2KA 4HG5A 3HKXA 3IVZA 1UF8A 2UXYA 3DLAA 4HGDA 4LF0A 3N05A 2VHIA 1UF7A 3ILVA 4CYFA 1FO6A 3KLCA 3SEQA 3WUYA 2VHHA 4IZUA 4IZWA 2E11A 5H8LA 5H8IA 5JQNA 3SEZA 1F89A 4H5UA 4HG3A 2E2LA 4CYYA 3SZGA 2DYVA 1UF4A 3SYTA 1UF5A 2DYUA 2PLQA 4IZTA 1J31A 2W1VA
chains in the Genus database with same CATH superfamily
2GGLA 3KI8A 4F4HA 1ERZA 3P8KA 4IZVA 4CYGA 3IW3A 5H8JA 4KZFA 2GGKA 4GYNA 5H8KA 4GYLA 1EMSA 5KHAA 3SDBA 4IZSA 2E2KA 4HG5A 3HKXA 3IVZA 1UF8A 2UXYA 3DLAA 4HGDA 4LF0A 3N05A 2VHIA 1UF7A 3ILVA 4CYFA 1FO6A 3KLCA 3SEQA 3WUYA 2VHHA 4IZUA 4IZWA 2E11A 5H8LA 5H8IA 5JQNA 3SEZA 1F89A 4H5UA 4HG3A 2E2LA 4CYYA 3SZGA 2DYVA 1UF4A 3SYTA 1UF5A 2DYUA 2PLQA 4IZTA 1J31A 2W1VA
chains in the Genus database with same CATH topology
2GGLA 3KI8A 4F4HA 1ERZA 3P8KA 4IZVA 4CYGA 3IW3A 5H8JA 4KZFA 2GGKA 4GYNA 5H8KA 4GYLA 1EMSA 5KHAA 3SDBA 4IZSA 2E2KA 4HG5A 3HKXA 3IVZA 1UF8A 2UXYA 3DLAA 4HGDA 4LF0A 3N05A 2VHIA 1UF7A 3ILVA 4CYFA 1FO6A 3KLCA 3SEQA 3WUYA 2VHHA 4IZUA 4IZWA 2E11A 5H8LA 5H8IA 5JQNA 3SEZA 1F89A 4H5UA 4HG3A 2E2LA 4CYYA 3SZGA 2DYVA 1UF4A 3SYTA 1UF5A 2DYUA 2PLQA 4IZTA 1J31A 2W1VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GGL A;  3KI8 A;  4F4H A;  1ERZ A;  3P8K A;  4IZV A;  4CYG A;  3IW3 A;  5H8J A;  4KZF A;  2GGK A;  4GYN A;  5H8K A;  4GYL A;  1EMS A;  5KHA A;  3SDB A;  4IZS A;  2E2K A;  4HG5 A;  3HKX A;  3IVZ A;  1UF8 A;  2UXY A;  3DLA A;  4HGD A;  4LF0 A;  3N05 A;  2VHI A;  1UF7 A;  3ILV A;  4CYF A;  1FO6 A;  3KLC A;  3SEQ A;  3WUY A;  2VHH A;  4IZU A;  4IZW A;  2E11 A;  5H8L A;  5H8I A;  5JQN A;  3SEZ A;  1F89 A;  4H5U A;  4HG3 A;  2E2L A;  4CYY A;  3SZG A;  2DYV A;  1UF4 A;  3SYT A;  1UF5 A;  2DYU A;  2PLQ A;  4IZT A;  1J31 A;  2W1V A; 
#chains in the Genus database with same CATH topology
 2GGL A;  3KI8 A;  4F4H A;  1ERZ A;  3P8K A;  4IZV A;  4CYG A;  3IW3 A;  5H8J A;  4KZF A;  2GGK A;  4GYN A;  5H8K A;  4GYL A;  1EMS A;  5KHA A;  3SDB A;  4IZS A;  2E2K A;  4HG5 A;  3HKX A;  3IVZ A;  1UF8 A;  2UXY A;  3DLA A;  4HGD A;  4LF0 A;  3N05 A;  2VHI A;  1UF7 A;  3ILV A;  4CYF A;  1FO6 A;  3KLC A;  3SEQ A;  3WUY A;  2VHH A;  4IZU A;  4IZW A;  2E11 A;  5H8L A;  5H8I A;  5JQN A;  3SEZ A;  1F89 A;  4H5U A;  4HG3 A;  2E2L A;  4CYY A;  3SZG A;  2DYV A;  1UF4 A;  3SYT A;  1UF5 A;  2DYU A;  2PLQ A;  4IZT A;  1J31 A;  2W1V A; 
#chains in the Genus database with same CATH homology
 2GGL A;  3KI8 A;  4F4H A;  1ERZ A;  3P8K A;  4IZV A;  4CYG A;  3IW3 A;  5H8J A;  4KZF A;  2GGK A;  4GYN A;  5H8K A;  4GYL A;  1EMS A;  5KHA A;  3SDB A;  4IZS A;  2E2K A;  4HG5 A;  3HKX A;  3IVZ A;  1UF8 A;  2UXY A;  3DLA A;  4HGD A;  4LF0 A;  3N05 A;  2VHI A;  1UF7 A;  3ILV A;  4CYF A;  1FO6 A;  3KLC A;  3SEQ A;  3WUY A;  2VHH A;  4IZU A;  4IZW A;  2E11 A;  5H8L A;  5H8I A;  5JQN A;  3SEZ A;  1F89 A;  4H5U A;  4HG3 A;  2E2L A;  4CYY A;  3SZG A;  2DYV A;  1UF4 A;  3SYT A;  1UF5 A;  2DYU A;  2PLQ A;  4IZT A;  1J31 A;  2W1V A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...