2XZVA

The cyanobacterial pp2c-like phosphatase tppha requires three metals in the catalytic center for efficient catalysis
Total Genus 73
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
73
sequence length
240
structure length
236
Chain Sequence
MDVAGLTDCGLIRKSNQDAFYIDEKHQRFFIVADGMGGEEASRLAVDHIRQYLETHLEDLQHDPVTLLRQAFLAANHAIVEQQRQNSARADMGTTAVVILLDEKGDRAWCAHVGDSRIYRWRKDQLQQITSDHTWIAQAVQLGSLTIEQARQHPWRHVLSQCLGREDLSQIDIQPIDLEPGDRLLLCSAGLTEELTDDVISIYLSEPNVQKAAAALVDAAKTHGGRDNVTVVVISV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Third Metal is Required for Catalytic Activity of the Signal-Transducing Protein Phosphatase M Tppha.
pubmed doi rcsb
molecule tags Hydrolase
source organism Synechococcus elongatus
molecule keywords PROTEIN SERIN-THREONIN PHOSPHATASE
total genus 73
structure length 236
sequence length 240
ec nomenclature
pdb deposition date 2010-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13672 PP2C_2 Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2xzvA00
4LGAB 5JO2B 3W42A 2I0OA 4OICB 3KDJB 3RT0A 5D2UA 2J86A 2JFTA 4RA2A 3T9QA 3ZVUB 4LGBB 5JO1B 3N3CA 4YZHA 2CM1A 3W43A 4DS8B 4YZGA 2ISNA 2IQ1A 2XZVA 3EQ2A 3UJLB 3MQ3A 3F79A 4LG5B 1TXOA 2POMA 5F1MA 3FXLA 3ZT9A 2IRMA 4RAGA 3ES2A 1A6QA 3QN1B 2Y09A 3W40A 3W41A 4N0GA 3FXKA 4RAFA 3NMNB 2POPA 3T91A 4DA1A 3D8KA 3JRQA 3PU9A 3RNRA 2JFRA 2J82A 3W44A 2P8EA 5ITIA 2PNQA 2I44A 3NMVB 2V06A 3UJKA 2J4OA 3NMTB 4WVOB 3W45A 3FXMA 3KE6A 4LA7B 4JNDA 3FXJA 2JFSA 2PK0A 3UJGB 3FXOA 3KB3B
chains in the Genus database with same CATH superfamily
4LGAB 5JO2B 3W42A 2I0OA 4OICB 3KDJB 3RT0A 5D2UA 2J86A 2JFTA 4RA2A 3T9QA 3ZVUB 4IIPA 4LGBB 5JO1B 3N3CA 4YZHA 2CM1A 3W43A 4DS8B 4YZGA 2ISNA 2IQ1A 2XZVA 3EQ2A 3UJLB 3MQ3A 3F79A 4LG5B 1TXOA 2POMA 5F1MA 3FXLA 3ZT9A 2IRMA 4RAGA 3ES2A 1A6QA 3QN1B 2Y09A 3W40A 3W41A 4N0GA 3FXKA 4RAFA 3NMNB 2POPA 3T91A 4DA1A 3D8KA 3JRQA 4IIKA 3PU9A 3RNRA 2JFRA 2J82A 3W44A 2P8EA 5ITIA 2PNQA 2I44A 3NMVB 2V06A 3UJKA 2J4OA 3NMTB 4WVOB 3W45A 3FXMA 3KE6A 4LA7B 4JNDA 3FXJA 2JFSA 2PK0A 3UJGB 3FXOA 3KB3B
chains in the Genus database with same CATH topology
4LGAB 5JO2B 3W42A 2I0OA 4OICB 3KDJB 3RT0A 5D2UA 2J86A 2JFTA 4RA2A 3T9QA 3ZVUB 4LGBB 5JO1B 3N3CA 4YZHA 2CM1A 3W43A 4DS8B 4YZGA 2ISNA 2IQ1A 2XZVA 3EQ2A 3UJLB 3MQ3A 3F79A 4LG5B 1TXOA 2POMA 5F1MA 3FXLA 3ZT9A 2IRMA 4RAGA 3ES2A 1A6QA 3QN1B 2Y09A 3W40A 3W41A 4N0GA 3FXKA 4RAFA 3NMNB 2POPA 3T91A 4DA1A 3D8KA 3JRQA 3PU9A 3RNRA 2JFRA 2J82A 3W44A 2P8EA 5ITIA 2PNQA 2I44A 3NMVB 2V06A 3UJKA 2J4OA 3NMTB 4WVOB 3W45A 3FXMA 3KE6A 4LA7B 4JNDA 3FXJA 2JFSA 2PK0A 3UJGB 3FXOA 3KB3B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LGA B;  5JO2 B;  3W42 A;  2I0O A;  4OIC B;  3KDJ B;  3RT0 A;  5D2U A;  2J86 A;  2JFT A;  4RA2 A;  3T9Q A;  3ZVU B;  4LGB B;  5JO1 B;  3N3C A;  4YZH A;  2CM1 A;  3W43 A;  4DS8 B;  4YZG A;  2ISN A;  2IQ1 A;  2XZV A;  3EQ2 A;  3UJL B;  3MQ3 A;  3F79 A;  4LG5 B;  1TXO A;  2POM A;  5F1M A;  3FXL A;  3ZT9 A;  2IRM A;  4RAG A;  3ES2 A;  1A6Q A;  3QN1 B;  2Y09 A;  3W40 A;  3W41 A;  4N0G A;  3FXK A;  4RAF A;  3NMN B;  2POP A;  3T91 A;  4DA1 A;  3D8K A;  3JRQ A;  3PU9 A;  3RNR A;  2JFR A;  2J82 A;  3W44 A;  2P8E A;  5ITI A;  2PNQ A;  2I44 A;  3NMV B;  2V06 A;  3UJK A;  2J4O A;  3NMT B;  4WVO B;  3W45 A;  3FXM A;  3KE6 A;  4LA7 B;  4JND A;  3FXJ A;  2JFS A;  2PK0 A;  3UJG B;  3FXO A;  3KB3 B; 
#chains in the Genus database with same CATH topology
 4LGA B;  5JO2 B;  3W42 A;  2I0O A;  4OIC B;  3KDJ B;  3RT0 A;  5D2U A;  2J86 A;  2JFT A;  4RA2 A;  3T9Q A;  3ZVU B;  4IIP A;  4LGB B;  5JO1 B;  3N3C A;  4YZH A;  2CM1 A;  3W43 A;  4DS8 B;  4YZG A;  2ISN A;  2IQ1 A;  2XZV A;  3EQ2 A;  3UJL B;  3MQ3 A;  3F79 A;  4LG5 B;  1TXO A;  2POM A;  5F1M A;  3FXL A;  3ZT9 A;  2IRM A;  4RAG A;  3ES2 A;  1A6Q A;  3QN1 B;  2Y09 A;  3W40 A;  3W41 A;  4N0G A;  3FXK A;  4RAF A;  3NMN B;  2POP A;  3T91 A;  4DA1 A;  3D8K A;  3JRQ A;  4IIK A;  3PU9 A;  3RNR A;  2JFR A;  2J82 A;  3W44 A;  2P8E A;  5ITI A;  2PNQ A;  2I44 A;  3NMV B;  2V06 A;  3UJK A;  2J4O A;  3NMT B;  4WVO B;  3W45 A;  3FXM A;  3KE6 A;  4LA7 B;  4JND A;  3FXJ A;  2JFS A;  2PK0 A;  3UJG B;  3FXO A;  3KB3 B; 
#chains in the Genus database with same CATH homology
 4LGA B;  5JO2 B;  3W42 A;  2I0O A;  4OIC B;  3KDJ B;  3RT0 A;  5D2U A;  2J86 A;  2JFT A;  4RA2 A;  3T9Q A;  3ZVU B;  4LGB B;  5JO1 B;  3N3C A;  4YZH A;  2CM1 A;  3W43 A;  4DS8 B;  4YZG A;  2ISN A;  2IQ1 A;  2XZV A;  3EQ2 A;  3UJL B;  3MQ3 A;  3F79 A;  4LG5 B;  1TXO A;  2POM A;  5F1M A;  3FXL A;  3ZT9 A;  2IRM A;  4RAG A;  3ES2 A;  1A6Q A;  3QN1 B;  2Y09 A;  3W40 A;  3W41 A;  4N0G A;  3FXK A;  4RAF A;  3NMN B;  2POP A;  3T91 A;  4DA1 A;  3D8K A;  3JRQ A;  3PU9 A;  3RNR A;  2JFR A;  2J82 A;  3W44 A;  2P8E A;  5ITI A;  2PNQ A;  2I44 A;  3NMV B;  2V06 A;  3UJK A;  2J4O A;  3NMT B;  4WVO B;  3W45 A;  3FXM A;  3KE6 A;  4LA7 B;  4JND A;  3FXJ A;  2JFS A;  2PK0 A;  3UJG B;  3FXO A;  3KB3 B; 
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