2Y09A

The cyanobacterial pp2c-like phosphatase tppha requires three metals in the catalytic center for efficient catalysis
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
240
structure length
236
Chain Sequence
MDVAGLTDCGLIRKSNQDAFYIDEKHQRFFIVADGMGGHAGGEEASRLAVDHIRQYLETHLEDLQHDPVTLLRQAFLAANHAIVEQQRQNSARADMGTTAVVILLDEKGDRAWCAHVGASRIYRWRKDQLQQITSDHTWIAQAVQLGSLARQHPWRHVLSQCLGREDLSQIDIQPIDLEPGDRLLLCSDGLTEELTDDVISIYLSEPNVQKAAAALVDAAKTHGGRDNVTVVVISV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Third Metal is Required for Catalytic Activity of the Signal-Transducing Protein Phosphatase M Tppha.
pubmed doi rcsb
molecule tags Hydrolase
source organism Synechococcus elongatus
molecule keywords PROTEIN SERIN-THREONIN PHOSPHATASE
total genus 77
structure length 236
sequence length 240
ec nomenclature
pdb deposition date 2010-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13672 PP2C_2 Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2y09A00
2J4OA 4N0GA 3W41A 3W44A 5F1MA 3T9QA 3W40A 4WVOB 3QN1B 3FXJA 4DA1A 2IQ1A 3D8KA 3NMNB 5JO1B 3F79A 2POPA 4DS8B 3JRQA 3RT0A 2PNQA 3UJLB 3KB3B 3N3CA 3W45A 3RNRA 5D2UA 5JO2B 3KDJB 2I44A 4JNDA 4YZHA 3UJKA 3MQ3A 2CM1A 2JFRA 5ITIA 2PK0A 2JFSA 4LG5B 3FXOA 3W42A 2P8EA 3PU9A 2POMA 3W43A 3NMTB 4LGBB 2I0OA 2IRMA 2Y09A 1A6QA 3ZT9A 3T91A 1TXOA 3FXLA 2J82A 2V06A 4LGAB 2JFTA 3FXMA 3NMVB 4OICB 3UJGB 3ZVUB 4LA7B 4YZGA 2J86A 3KE6A 4RAGA 2ISNA 4RAFA 3EQ2A 4RA2A 3ES2A 2XZVA 3FXKA
chains in the Genus database with same CATH superfamily
2J4OA 4N0GA 3W41A 3W44A 5F1MA 3T9QA 3W40A 4WVOB 3QN1B 3FXJA 4DA1A 2IQ1A 3D8KA 3NMNB 4IIPA 5JO1B 3F79A 2POPA 4DS8B 3JRQA 3RT0A 2PNQA 3UJLB 3KB3B 3N3CA 3W45A 3RNRA 5D2UA 5JO2B 3KDJB 2I44A 4JNDA 4YZHA 3UJKA 3MQ3A 2CM1A 2JFRA 5ITIA 2PK0A 2JFSA 4LG5B 3FXOA 3W42A 2P8EA 3PU9A 2POMA 3W43A 3NMTB 4LGBB 2I0OA 2IRMA 2Y09A 1A6QA 3ZT9A 3T91A 1TXOA 3FXLA 2J82A 2V06A 4LGAB 4IIKA 2JFTA 3FXMA 3NMVB 4OICB 3UJGB 3ZVUB 4LA7B 4YZGA 2J86A 3KE6A 4RAGA 2ISNA 4RAFA 3EQ2A 4RA2A 3ES2A 2XZVA 3FXKA
chains in the Genus database with same CATH topology
2J4OA 4N0GA 3W41A 3W44A 5F1MA 3T9QA 3W40A 4WVOB 3QN1B 3FXJA 4DA1A 2IQ1A 3D8KA 3NMNB 5JO1B 3F79A 2POPA 4DS8B 3JRQA 3RT0A 2PNQA 3UJLB 3KB3B 3N3CA 3W45A 3RNRA 5D2UA 5JO2B 3KDJB 2I44A 4JNDA 4YZHA 3UJKA 3MQ3A 2CM1A 2JFRA 5ITIA 2PK0A 2JFSA 4LG5B 3FXOA 3W42A 2P8EA 3PU9A 2POMA 3W43A 3NMTB 4LGBB 2I0OA 2IRMA 2Y09A 1A6QA 3ZT9A 3T91A 1TXOA 3FXLA 2J82A 2V06A 4LGAB 2JFTA 3FXMA 3NMVB 4OICB 3UJGB 3ZVUB 4LA7B 4YZGA 2J86A 3KE6A 4RAGA 2ISNA 4RAFA 3EQ2A 4RA2A 3ES2A 2XZVA 3FXKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J4O A;  4N0G A;  3W41 A;  3W44 A;  5F1M A;  3T9Q A;  3W40 A;  4WVO B;  3QN1 B;  3FXJ A;  4DA1 A;  2IQ1 A;  3D8K A;  3NMN B;  5JO1 B;  3F79 A;  2POP A;  4DS8 B;  3JRQ A;  3RT0 A;  2PNQ A;  3UJL B;  3KB3 B;  3N3C A;  3W45 A;  3RNR A;  5D2U A;  5JO2 B;  3KDJ B;  2I44 A;  4JND A;  4YZH A;  3UJK A;  3MQ3 A;  2CM1 A;  2JFR A;  5ITI A;  2PK0 A;  2JFS A;  4LG5 B;  3FXO A;  3W42 A;  2P8E A;  3PU9 A;  2POM A;  3W43 A;  3NMT B;  4LGB B;  2I0O A;  2IRM A;  2Y09 A;  1A6Q A;  3ZT9 A;  3T91 A;  1TXO A;  3FXL A;  2J82 A;  2V06 A;  4LGA B;  2JFT A;  3FXM A;  3NMV B;  4OIC B;  3UJG B;  3ZVU B;  4LA7 B;  4YZG A;  2J86 A;  3KE6 A;  4RAG A;  2ISN A;  4RAF A;  3EQ2 A;  4RA2 A;  3ES2 A;  2XZV A;  3FXK A; 
#chains in the Genus database with same CATH topology
 2J4O A;  4N0G A;  3W41 A;  3W44 A;  5F1M A;  3T9Q A;  3W40 A;  4WVO B;  3QN1 B;  3FXJ A;  4DA1 A;  2IQ1 A;  3D8K A;  3NMN B;  4IIP A;  5JO1 B;  3F79 A;  2POP A;  4DS8 B;  3JRQ A;  3RT0 A;  2PNQ A;  3UJL B;  3KB3 B;  3N3C A;  3W45 A;  3RNR A;  5D2U A;  5JO2 B;  3KDJ B;  2I44 A;  4JND A;  4YZH A;  3UJK A;  3MQ3 A;  2CM1 A;  2JFR A;  5ITI A;  2PK0 A;  2JFS A;  4LG5 B;  3FXO A;  3W42 A;  2P8E A;  3PU9 A;  2POM A;  3W43 A;  3NMT B;  4LGB B;  2I0O A;  2IRM A;  2Y09 A;  1A6Q A;  3ZT9 A;  3T91 A;  1TXO A;  3FXL A;  2J82 A;  2V06 A;  4LGA B;  4IIK A;  2JFT A;  3FXM A;  3NMV B;  4OIC B;  3UJG B;  3ZVU B;  4LA7 B;  4YZG A;  2J86 A;  3KE6 A;  4RAG A;  2ISN A;  4RAF A;  3EQ2 A;  4RA2 A;  3ES2 A;  2XZV A;  3FXK A; 
#chains in the Genus database with same CATH homology
 2J4O A;  4N0G A;  3W41 A;  3W44 A;  5F1M A;  3T9Q A;  3W40 A;  4WVO B;  3QN1 B;  3FXJ A;  4DA1 A;  2IQ1 A;  3D8K A;  3NMN B;  5JO1 B;  3F79 A;  2POP A;  4DS8 B;  3JRQ A;  3RT0 A;  2PNQ A;  3UJL B;  3KB3 B;  3N3C A;  3W45 A;  3RNR A;  5D2U A;  5JO2 B;  3KDJ B;  2I44 A;  4JND A;  4YZH A;  3UJK A;  3MQ3 A;  2CM1 A;  2JFR A;  5ITI A;  2PK0 A;  2JFS A;  4LG5 B;  3FXO A;  3W42 A;  2P8E A;  3PU9 A;  2POM A;  3W43 A;  3NMT B;  4LGB B;  2I0O A;  2IRM A;  2Y09 A;  1A6Q A;  3ZT9 A;  3T91 A;  1TXO A;  3FXL A;  2J82 A;  2V06 A;  4LGA B;  2JFT A;  3FXM A;  3NMV B;  4OIC B;  3UJG B;  3ZVU B;  4LA7 B;  4YZG A;  2J86 A;  3KE6 A;  4RAG A;  2ISN A;  4RAF A;  3EQ2 A;  4RA2 A;  3ES2 A;  2XZV A;  3FXK A; 
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