2Y09A

The cyanobacterial pp2c-like phosphatase tppha requires three metals in the catalytic center for efficient catalysis
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
240
structure length
236
Chain Sequence
MDVAGLTDCGLIRKSNQDAFYIDEKHQRFFIVADGMGGHAGGEEASRLAVDHIRQYLETHLEDLQHDPVTLLRQAFLAANHAIVEQQRQNSARADMGTTAVVILLDEKGDRAWCAHVGASRIYRWRKDQLQQITSDHTWIAQAVQLGSLARQHPWRHVLSQCLGREDLSQIDIQPIDLEPGDRLLLCSDGLTEELTDDVISIYLSEPNVQKAAAALVDAAKTHGGRDNVTVVVISV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Third Metal is Required for Catalytic Activity of the Signal-Transducing Protein Phosphatase M Tppha.
pubmed doi rcsb
molecule tags Hydrolase
source organism Synechococcus elongatus
molecule keywords PROTEIN SERIN-THREONIN PHOSPHATASE
total genus 77
structure length 236
sequence length 240
ec nomenclature
pdb deposition date 2010-12-01

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF13672 PP2C_2 Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2y09A00
4YZHA 3EQ2A 3FXMA 2IQ1A 4LG5B 5JO1B 5JO2B 3FXLA 4RAFA 3F79A 3NMTB 2JFSA 4LA7B 2V06A 2P8EA 2Y09A 3W44A 3FXKA 2J82A 2PK0A 3KE6A 2I0OA 2I44A 5ITIA 2CM1A 3MQ3A 4RAGA 3T91A 4YZGA 1A6QA 2POPA 3QN1B 3W40A 2POMA 1TXOA 3W42A 4N0GA 3ES2A 3W41A 3RNRA 4LGAB 4OICB 3PU9A 2PNQA 5D2UA 2XZVA 3ZVUB 4DA1A 3KB3B 3N3CA 4WVOB 2JFTA 2J4OA 3ZT9A 4LGBB 3UJKA 3T9QA 3W45A 3UJGB 3JRQA 2J86A 4RA2A 2IRMA 3FXJA 3W43A 3UJLB 3NMNB 3D8KA 2JFRA 5F1MA 2ISNA 3FXOA 3NMVB 4JNDA 4DS8B 3KDJB 3RT0A
chains in the Genus database with same CATH superfamily
4YZHA 3EQ2A 3FXMA 2IQ1A 4LG5B 5JO1B 5JO2B 4IIKA 3FXLA 4RAFA 3F79A 3NMTB 2JFSA 4LA7B 2V06A 2P8EA 2Y09A 3W44A 3FXKA 4IIPA 2J82A 2PK0A 3KE6A 2I0OA 2I44A 5ITIA 2CM1A 3MQ3A 4RAGA 3T91A 4YZGA 1A6QA 2POPA 3QN1B 3W40A 2POMA 1TXOA 3W42A 4N0GA 3ES2A 3W41A 3RNRA 4LGAB 4OICB 3PU9A 2PNQA 5D2UA 2XZVA 3ZVUB 4DA1A 3KB3B 3N3CA 4WVOB 2JFTA 2J4OA 3ZT9A 4LGBB 3UJKA 3T9QA 3W45A 3UJGB 3JRQA 2J86A 4RA2A 2IRMA 3FXJA 3W43A 3UJLB 3NMNB 3D8KA 2JFRA 5F1MA 2ISNA 3FXOA 3NMVB 4JNDA 4DS8B 3KDJB 3RT0A
chains in the Genus database with same CATH topology
4YZHA 3EQ2A 3FXMA 2IQ1A 4LG5B 5JO1B 5JO2B 3FXLA 4RAFA 3F79A 3NMTB 2JFSA 4LA7B 2V06A 2P8EA 2Y09A 3W44A 3FXKA 2J82A 2PK0A 3KE6A 2I0OA 2I44A 5ITIA 2CM1A 3MQ3A 4RAGA 3T91A 4YZGA 1A6QA 2POPA 3QN1B 3W40A 2POMA 1TXOA 3W42A 4N0GA 3ES2A 3W41A 3RNRA 4LGAB 4OICB 3PU9A 2PNQA 5D2UA 2XZVA 3ZVUB 4DA1A 3KB3B 3N3CA 4WVOB 2JFTA 2J4OA 3ZT9A 4LGBB 3UJKA 3T9QA 3W45A 3UJGB 3JRQA 2J86A 4RA2A 2IRMA 3FXJA 3W43A 3UJLB 3NMNB 3D8KA 2JFRA 5F1MA 2ISNA 3FXOA 3NMVB 4JNDA 4DS8B 3KDJB 3RT0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YZH A;  3EQ2 A;  3FXM A;  2IQ1 A;  4LG5 B;  5JO1 B;  5JO2 B;  3FXL A;  4RAF A;  3F79 A;  3NMT B;  2JFS A;  4LA7 B;  2V06 A;  2P8E A;  2Y09 A;  3W44 A;  3FXK A;  2J82 A;  2PK0 A;  3KE6 A;  2I0O A;  2I44 A;  5ITI A;  2CM1 A;  3MQ3 A;  4RAG A;  3T91 A;  4YZG A;  1A6Q A;  2POP A;  3QN1 B;  3W40 A;  2POM A;  1TXO A;  3W42 A;  4N0G A;  3ES2 A;  3W41 A;  3RNR A;  4LGA B;  4OIC B;  3PU9 A;  2PNQ A;  5D2U A;  2XZV A;  3ZVU B;  4DA1 A;  3KB3 B;  3N3C A;  4WVO B;  2JFT A;  2J4O A;  3ZT9 A;  4LGB B;  3UJK A;  3T9Q A;  3W45 A;  3UJG B;  3JRQ A;  2J86 A;  4RA2 A;  2IRM A;  3FXJ A;  3W43 A;  3UJL B;  3NMN B;  3D8K A;  2JFR A;  5F1M A;  2ISN A;  3FXO A;  3NMV B;  4JND A;  4DS8 B;  3KDJ B;  3RT0 A; 
#chains in the Genus database with same CATH topology
 4YZH A;  3EQ2 A;  3FXM A;  2IQ1 A;  4LG5 B;  5JO1 B;  5JO2 B;  4IIK A;  3FXL A;  4RAF A;  3F79 A;  3NMT B;  2JFS A;  4LA7 B;  2V06 A;  2P8E A;  2Y09 A;  3W44 A;  3FXK A;  4IIP A;  2J82 A;  2PK0 A;  3KE6 A;  2I0O A;  2I44 A;  5ITI A;  2CM1 A;  3MQ3 A;  4RAG A;  3T91 A;  4YZG A;  1A6Q A;  2POP A;  3QN1 B;  3W40 A;  2POM A;  1TXO A;  3W42 A;  4N0G A;  3ES2 A;  3W41 A;  3RNR A;  4LGA B;  4OIC B;  3PU9 A;  2PNQ A;  5D2U A;  2XZV A;  3ZVU B;  4DA1 A;  3KB3 B;  3N3C A;  4WVO B;  2JFT A;  2J4O A;  3ZT9 A;  4LGB B;  3UJK A;  3T9Q A;  3W45 A;  3UJG B;  3JRQ A;  2J86 A;  4RA2 A;  2IRM A;  3FXJ A;  3W43 A;  3UJL B;  3NMN B;  3D8K A;  2JFR A;  5F1M A;  2ISN A;  3FXO A;  3NMV B;  4JND A;  4DS8 B;  3KDJ B;  3RT0 A; 
#chains in the Genus database with same CATH homology
 4YZH A;  3EQ2 A;  3FXM A;  2IQ1 A;  4LG5 B;  5JO1 B;  5JO2 B;  3FXL A;  4RAF A;  3F79 A;  3NMT B;  2JFS A;  4LA7 B;  2V06 A;  2P8E A;  2Y09 A;  3W44 A;  3FXK A;  2J82 A;  2PK0 A;  3KE6 A;  2I0O A;  2I44 A;  5ITI A;  2CM1 A;  3MQ3 A;  4RAG A;  3T91 A;  4YZG A;  1A6Q A;  2POP A;  3QN1 B;  3W40 A;  2POM A;  1TXO A;  3W42 A;  4N0G A;  3ES2 A;  3W41 A;  3RNR A;  4LGA B;  4OIC B;  3PU9 A;  2PNQ A;  5D2U A;  2XZV A;  3ZVU B;  4DA1 A;  3KB3 B;  3N3C A;  4WVO B;  2JFT A;  2J4O A;  3ZT9 A;  4LGB B;  3UJK A;  3T9Q A;  3W45 A;  3UJG B;  3JRQ A;  2J86 A;  4RA2 A;  2IRM A;  3FXJ A;  3W43 A;  3UJL B;  3NMN B;  3D8K A;  2JFR A;  5F1M A;  2ISN A;  3FXO A;  3NMV B;  4JND A;  4DS8 B;  3KDJ B;  3RT0 A; 
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