2YPAC

Structure of the scl:e47:lmo2:ldb1 complex bound to dna
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
126
structure length
126
Chain Sequence
CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets.
pubmed doi rcsb
molecule tags Immune system
source organism Homo sapiens
molecule keywords T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1
total genus 20
structure length 126
sequence length 126
ec nomenclature
pdb deposition date 2012-10-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 2ypaC02
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 2ypaC01
1X64A 2CO8A 2EHEA 3F6QB 3MMKA 1A7IA 1IBIA 1X6AA 4HI8B 4JCJA 1NYPA 1CTLA 2YPAC 1CXXA 2DLOA 1RUTX 2DFYC 2KBXB 1U5SB 1X3HA 1QLIA 2CU8A 2L6ZC 2LZUA 1G47A 2IYBE 1X62A 2D8XA 2L4ZA 2LXDA 4KFZA 2O10A 2XQNT 1V6GA 1X63A 2XJYA 1X61A 1X4LA 4HI9B 1IMLA 1J2OA 2CUPA 2CUQA 2DARA 2L6YB 2D8YA 2MBVA 1WIGA 2JTNA 1WYHA 2O13A 2XJZA 2CORA 1X68A 2EGQA 1B8TA 2D8ZA 2MIUA 2DJ7A 3IXEB 2CURA 1M3VA
chains in the Genus database with same CATH superfamily
5FYMA 3MMKA 1X6AA 5LKZA 2DLOA 1QLIA 4UF0A 1X62A 5FXZA 1J2OA 1X4LA 5LKUA 2DARA 1WIGA 3AVSA 1B8TA 4EYUA 2MIUA 3ZPOA 3IXEB 2CURA 5A1LA 2CO8A 3F6QB 3NISA 2YPAC 5FY0A 1RUTX 2KBXB 1U5SB 2CU8A 1G47A 2IYBE 4EZ4A 2D8XA 2LXDA 4KFZA 2XQNT 4HI9B 1X61A 4EZHA 2CUPA 2D8YA 1WYHA 3AVRA 2CORA 3NIKA 3NIJA 2D8ZA 2DJ7A 5FY7A 3NILA 1M3VA 2EHEA 3NIHA 5FXXA 1IBIA 2XUEA 4HI8B 1NYPA 1CXXA 2DFYC 3ZLIA 4UF0B 2LZUA 1V6GA 2XJYA 1IMLA 5FXVA 2CUQA 2JTNA 2XJZA 2O13A 4ASKA 5LKXA 3NIMA 1X64A 1A7IA 5LKTA 4JCJA 1CTLA 1X3HA 5FY1A 2L6ZC 2L4ZA 2O10A 1X63A 2L6YB 2MBVA 4BHWA 1X68A 5FP3A 2EGQA 5FXWA 3NINA
chains in the Genus database with same CATH topology
5FYMA 3MMKA 1X6AA 5LKZA 2DLOA 1QLIA 4UF0A 1X62A 5FXZA 1J2OA 1X4LA 5LKUA 2DARA 1WIGA 3AVSA 1B8TA 4EYUA 2MIUA 3ZPOA 3IXEB 2CURA 5A1LA 2CO8A 3F6QB 3NISA 2YPAC 5FY0A 1RUTX 2KBXB 1U5SB 2CU8A 1G47A 2IYBE 4EZ4A 2D8XA 2LXDA 4KFZA 2XQNT 4HI9B 1X61A 4EZHA 2CUPA 2D8YA 1WYHA 3AVRA 2CORA 3NIKA 3NIJA 2D8ZA 2DJ7A 5FY7A 3NILA 1M3VA 2EHEA 3NIHA 5FXXA 1IBIA 2XUEA 4HI8B 1NYPA 1CXXA 2DFYC 3ZLIA 4UF0B 2LZUA 1V6GA 2XJYA 1IMLA 5FXVA 2CUQA 2JTNA 2XJZA 2O13A 4ASKA 5LKXA 3NIMA 1X64A 1A7IA 5LKTA 4JCJA 1CTLA 1X3HA 5FY1A 2L6ZC 2L4ZA 2O10A 1X63A 2L6YB 2MBVA 4BHWA 1X68A 5FP3A 2EGQA 5FXWA 3NINA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1X64 A;  2CO8 A;  2EHE A;  3F6Q B;  3MMK A;  1A7I A;  1IBI A;  1X6A A;  4HI8 B;  4JCJ A;  1NYP A;  1CTL A;  2YPA C;  1CXX A;  2DLO A;  1RUT X;  2DFY C;  2KBX B;  1U5S B;  1X3H A;  1QLI A;  2CU8 A;  2L6Z C;  2LZU A;  1G47 A;  2IYB E;  1X62 A;  2D8X A;  2L4Z A;  2LXD A;  4KFZ A;  2O10 A;  2XQN T;  1V6G A;  1X63 A;  2XJY A;  1X61 A;  1X4L A;  4HI9 B;  1IML A;  1J2O A;  2CUP A;  2CUQ A;  2DAR A;  2L6Y B;  2D8Y A;  2MBV A;  1WIG A;  2JTN A;  1WYH A;  2O13 A;  2XJZ A;  2COR A;  1X68 A;  2EGQ A;  1B8T A;  2D8Z A;  2MIU A;  2DJ7 A;  3IXE B;  2CUR A;  1M3V A; 
#chains in the Genus database with same CATH topology
 5FYM A;  3MMK A;  1X6A A;  5LKZ A;  2DLO A;  1QLI A;  4UF0 A;  1X62 A;  5FXZ A;  1J2O A;  1X4L A;  5LKU A;  2DAR A;  1WIG A;  3AVS A;  1B8T A;  4EYU A;  2MIU A;  3ZPO A;  3IXE B;  2CUR A;  5A1L A;  2CO8 A;  3F6Q B;  3NIS A;  2YPA C;  5FY0 A;  1RUT X;  2KBX B;  1U5S B;  2CU8 A;  1G47 A;  2IYB E;  4EZ4 A;  2D8X A;  2LXD A;  4KFZ A;  2XQN T;  4HI9 B;  1X61 A;  4EZH A;  2CUP A;  2D8Y A;  1WYH A;  3AVR A;  2COR A;  3NIK A;  3NIJ A;  2D8Z A;  2DJ7 A;  5FY7 A;  3NIL A;  1M3V A;  2EHE A;  3NIH A;  5FXX A;  1IBI A;  2XUE A;  4HI8 B;  1NYP A;  1CXX A;  2DFY C;  3ZLI A;  4UF0 B;  2LZU A;  1V6G A;  2XJY A;  1IML A;  5FXV A;  2CUQ A;  2JTN A;  2XJZ A;  2O13 A;  4ASK A;  5LKX A;  3NIM A;  1X64 A;  1A7I A;  5LKT A;  4JCJ A;  1CTL A;  1X3H A;  5FY1 A;  2L6Z C;  2L4Z A;  2O10 A;  1X63 A;  2L6Y B;  2MBV A;  4BHW A;  1X68 A;  5FP3 A;  2EGQ A;  5FXW A;  3NIN A; 
#chains in the Genus database with same CATH homology
 5FYM A;  3MMK A;  1X6A A;  5LKZ A;  2DLO A;  1QLI A;  4UF0 A;  1X62 A;  5FXZ A;  1J2O A;  1X4L A;  5LKU A;  2DAR A;  1WIG A;  3AVS A;  1B8T A;  4EYU A;  2MIU A;  3ZPO A;  3IXE B;  2CUR A;  5A1L A;  2CO8 A;  3F6Q B;  3NIS A;  2YPA C;  5FY0 A;  1RUT X;  2KBX B;  1U5S B;  2CU8 A;  1G47 A;  2IYB E;  4EZ4 A;  2D8X A;  2LXD A;  4KFZ A;  2XQN T;  4HI9 B;  1X61 A;  4EZH A;  2CUP A;  2D8Y A;  1WYH A;  3AVR A;  2COR A;  3NIK A;  3NIJ A;  2D8Z A;  2DJ7 A;  5FY7 A;  3NIL A;  1M3V A;  2EHE A;  3NIH A;  5FXX A;  1IBI A;  2XUE A;  4HI8 B;  1NYP A;  1CXX A;  2DFY C;  3ZLI A;  4UF0 B;  2LZU A;  1V6G A;  2XJY A;  1IML A;  5FXV A;  2CUQ A;  2JTN A;  2XJZ A;  2O13 A;  4ASK A;  5LKX A;  3NIM A;  1X64 A;  1A7I A;  5LKT A;  4JCJ A;  1CTL A;  1X3H A;  5FY1 A;  2L6Z C;  2L4Z A;  2O10 A;  1X63 A;  2L6Y B;  2MBV A;  4BHW A;  1X68 A;  5FP3 A;  2EGQ A;  5FXW A;  3NIN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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