2E2HF

Rna polymerase ii elongation complex at 5 mm mg2+ with gtp
Total Genus 13
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
13
sequence length
83
structure length
83
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 13
structure length 83
sequence length 83
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 2e2hF00
1R9TF 4ZH4E 2R93F 5IPLE 5M3MF 2E2HF 4A3KF 1IW7E 3S1RF 5TMFE 4BBRF 3S15F 5C3EF 3HOVF 1K83F 3GTOF 4XSXE 3H0GF 3HOWF 2A6HE 4YG2E 1TWFF 4BXXF 4MQ9E 5IYDF 4C2MF 5M5YF 2R7ZF 5M5XF 3S17F 4LK0E 2JA7F 5D4DE 2PPBE 4Q4ZE 2JA8F 3H3VG 2NVYF 4MEYE 2BE5E 4XLPE 4YFKE 5C4XF 3I4NF 4A3BF 2A69E 2YU9F 4LK1E 2B63F 4A3CF 3PO2F 4C3IF 4G7ZE 1TWCF 3GTMF 3DXJE 2CW0E 4BY7F 1I6HF 2JA6F 3RZDF 4A3FF 5M3FF 4X6AF 4OIOE 4AYBK 3GTKF 4OINE 5D4EE 3M4OF 4A3DF 3PO3F 3HOZF 1YNJK 2WB1I 5IYBF 1WCMF 3FKIF 3HOUF 4BBSF 5C4JF 4G7HE 3S2DF 3S1QF 4G7OE 2E2JF 5BYHE 3GTGF 4KN4E 1SMYE 3S16F 4A3GF 5E17E 2PMZK 5FJ8F 4GZYE 4KMUE 4C3HF 2R92F 3S1MF 3HOXF 1TWGF 3GTJF 5IYCF 3S14F 3EQLE 4A3IF 2JA5F 4LLGE 4A3JF 3GTPF 4JK1E 4XLNE 3GTLF 1QKLA 4A93F 5E18E 1TWAF 2VUMF 4KN7E 3RZOF 1HQME 4BY1F 3GTQF 2NVTF 3S2HF 4A3EF 4Y52F 1I50F 4MEXE 3S1NF 2NVQF 3HOYF 1Y1VF 3WODE 4C3JF 2O5IE 2E2IF 4Y7NF 3CQZF 5D4CE 4OIPE 4LJZE 4YFNE 3K7AF 1SFOF 5TMCE 4A3MF 3M3YF 4YFXE 3HKZK 1I6VE 2A68E 3I4MF 4A3LF 1YNNK 1Y1WF 4OIRE 1ZYRE 4OIQE 5M5WF 2NVXF 2O5JE 5IP9F 4Q5SE 2Y0SI 1TWHF 2A6EE 5IP7F 5C44F 1I3QF 2WAQK 4XSZE 5FLMF
chains in the Genus database with same CATH superfamily
2NVXE 5IP9E 1R9TF 1TWHE 4ZH4E 5IP7E 5C44E 5M3MF 2E2HF 2R93F 4A3KF 1I3QE 1IW7E 3S1RF 5TMFE 5FLME 4BBRF 3S15F 5C3EF 3HOVF 1K83F 3GTOF 4XSXE 3H0GF 3HOWF 1R9TE 2A6HE 2R93E 4YG2E 5M3ME 1TWFF 2E2HE 4A3KE 4MQ9E 5IYDF 3S1RE 4BXXF 4C2MF 5M5YF 4BBRE 2R7ZF 5C3EE 3HOVE 1K83E 5M5XF 3GTOE 3S15E 3HOWE 3S17F 4LK0E 2JA7F 1TWFE 4BXXE 5IYDE 5D4DE 2PMZH 2PPBE 4C2ME 4Q4ZE 5M5YE 2R7ZE 2JA8F 1DZFA 2NVYF 5M5XE 3H3VG 4MEYE 2BE5E 3S17E 4XLPE 4YFKE 5C4XF 3I4NF 4A3BF 2A69E 2YU9F 4LK1E 2B63F 4AYBH 3PO2F 4A3CF 1EIKA 4C3IF 4G7ZE 1TWCF 2JA8E 2NVYE 3DXJE 2CW0E 3GTMF 4BY7F 1I6HF 4QIWH 2JA6F 5C4XE 3RZDF 4A3FF 5M3FF 3I4NE 4OIOE 4A3BE 4X6AF 2YU9E 2B63E 4A3CE 3PO2E 4AYBK 3GTKF 4C3IE 2KRXA 1TWCE 3GTME 4OINE 5D4EE 2Y0SH 4BY7E 3M4OF 2JA6E 4A3DF 3RZDE 4A3FE 3PO3F 5M3FE 4X6AE 3HOZF 1YNJK 2WB1I 3H0GE 3GTKE 5IYBF 1WCMF 3FKIF 3HOUF 4BBSF 5C4JF 4G7HE 3S2DF 3M4OE 4A3DE 3S1QF 3PO3E 4G7OE 3HOZE 2E2JF 5BYHE 5IYBE 1WCME 2JA7E 3GTGF 3FKIE 4KN4E 3HKZH 3HOUE 1SMYE 5C4JE 3S16F 4BBSE 2PMZK 3S1QE 5FJ8F 3S2DE 4GZYE 4A3GF 5E17E 2E2JE 4KMUE 4C3HF 2R92F 3GTGE 3S1MF 3HOXF 1TWGF 3S16E 4A3GE 5FJ8E 3GTJF 5IYCF 3S14F 5IPLE 3EQLE 4A3IF 2JA5F 4LLGE 4A3JF 3H3VF 1I6HE 4C3HE 2R92E 4QIWK 3GTPF 4JK1E 3S1ME 3HOXE 1TWGE 4XLNE 3GTLF 1QKLA 4A93F 5E18E 5IYCE 1TWAF 3GTJE 3S14E 4A3IE 2JA5E 2VUMF 4A3JE 4KN7E 3RZOF 1HQME 3GTPE 4BY1F 3GTLE 4A93E 3GTQF 2NVTF 1TWAE 2VUME 3S2HF 4A3EF 4Y52F 1I50F 4MEXE 3S1NF 3RZOE 2NVQF 3HOYF 1Y1VF 3WODE 4BY1E 4C3JF 2O5IE 2E2IF 4Y7NF 3CQZF 5D4CE 4OIPE 3GTQE 4LJZE 4YFNE 3K7AF 1SFOF 2NVTE 3S2HE 4A3EE 5TMCE 4A3MF 2WB1H 1I50E 4YFXE 3M3YF 3HKZK 3S1NE 4Y52E 1I6VE 2A68E 2NVQE 3HOYE 1Y1VE 3I4MF 4C3JE 4A3LF 2E2IE 2WAQH 3CQZE 1YNNK 4Y7NE 1Y1WF 4OIRE 3K7AE 1SFOE 1ZYRE 4OIQE 5M5WF 2NVXF 4A3ME 3M3YE 5IP9F 2O5JE 4Q5SE 2Y0SI 3I4ME 1TWHF 2A6EE 5IP7F 5C44F 4A3LE 1I3QF 2WAQK 4XSZE 1Y1WE 5FLMF 5M5WE
chains in the Genus database with same CATH topology
1R9TF 4ZH4E 2R93F 5IPLE 5M3MF 2E2HF 4A3KF 1IW7E 3S1RF 5TMFE 4BBRF 3S15F 5C3EF 3HOVF 1K83F 3GTOF 4XSXE 3H0GF 3HOWF 2A6HE 4YG2E 1TWFF 4BXXF 4MQ9E 5IYDF 4C2MF 5M5YF 2R7ZF 5M5XF 3S17F 4LK0E 2JA7F 5D4DE 2PPBE 4Q4ZE 2JA8F 3H3VG 2NVYF 4MEYE 2BE5E 4XLPE 4YFKE 5C4XF 3I4NF 4A3BF 2A69E 2YU9F 4LK1E 2B63F 4A3CF 3PO2F 4C3IF 4G7ZE 1TWCF 3GTMF 3DXJE 2CW0E 4BY7F 1I6HF 2JA6F 3RZDF 4A3FF 5M3FF 4X6AF 4OIOE 4AYBK 3GTKF 2KRXA 4OINE 5D4EE 3M4OF 4A3DF 3PO3F 3HOZF 1YNJK 2WB1I 5IYBF 1WCMF 3FKIF 3HOUF 4BBSF 5C4JF 4G7HE 3S2DF 3S1QF 4G7OE 2E2JF 5BYHE 3GTGF 4KN4E 1SMYE 3S16F 4A3GF 5E17E 2PMZK 5FJ8F 4GZYE 4KMUE 4C3HF 2R92F 3S1MF 3HOXF 1TWGF 3GTJF 5IYCF 3S14F 3EQLE 4A3IF 2JA5F 4LLGE 4A3JF 4QIWK 3GTPF 4JK1E 4XLNE 3GTLF 1QKLA 4A93F 5E18E 1TWAF 2VUMF 4KN7E 3RZOF 1HQME 4BY1F 3GTQF 2NVTF 3S2HF 4A3EF 4Y52F 1I50F 4MEXE 3S1NF 2NVQF 3HOYF 1Y1VF 3WODE 4C3JF 2O5IE 2E2IF 4Y7NF 3CQZF 5D4CE 4OIPE 4LJZE 4YFNE 3K7AF 1SFOF 5TMCE 4A3MF 3M3YF 4YFXE 3HKZK 1I6VE 2A68E 3I4MF 4A3LF 1YNNK 1Y1WF 4OIRE 1ZYRE 4OIQE 5M5WF 2NVXF 2O5JE 5IP9F 4Q5SE 2Y0SI 1TWHF 2A6EE 5IP7F 5C44F 1I3QF 2WAQK 4XSZE 5FLMF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R9T F;  4ZH4 E;  2R93 F;  5IPL E;  5M3M F;  2E2H F;  4A3K F;  1IW7 E;  3S1R F;  5TMF E;  4BBR F;  3S15 F;  5C3E F;  3HOV F;  1K83 F;  3GTO F;  4XSX E;  3H0G F;  3HOW F;  2A6H E;  4YG2 E;  1TWF F;  4BXX F;  4MQ9 E;  5IYD F;  4C2M F;  5M5Y F;  2R7Z F;  5M5X F;  3S17 F;  4LK0 E;  2JA7 F;  5D4D E;  2PPB E;  4Q4Z E;  2JA8 F;  3H3V G;  2NVY F;  4MEY E;  2BE5 E;  4XLP E;  4YFK E;  5C4X F;  3I4N F;  4A3B F;  2A69 E;  2YU9 F;  4LK1 E;  2B63 F;  4A3C F;  3PO2 F;  4C3I F;  4G7Z E;  1TWC F;  3GTM F;  3DXJ E;  2CW0 E;  4BY7 F;  1I6H F;  2JA6 F;  3RZD F;  4A3F F;  5M3F F;  4X6A F;  4OIO E;  4AYB K;  3GTK F;  4OIN E;  5D4E E;  3M4O F;  4A3D F;  3PO3 F;  3HOZ F;  1YNJ K;  2WB1 I;  5IYB F;  1WCM F;  3FKI F;  3HOU F;  4BBS F;  5C4J F;  4G7H E;  3S2D F;  3S1Q F;  4G7O E;  2E2J F;  5BYH E;  3GTG F;  4KN4 E;  1SMY E;  3S16 F;  4A3G F;  5E17 E;  2PMZ K;  5FJ8 F;  4GZY E;  4KMU E;  4C3H F;  2R92 F;  3S1M F;  3HOX F;  1TWG F;  3GTJ F;  5IYC F;  3S14 F;  3EQL E;  4A3I F;  2JA5 F;  4LLG E;  4A3J F;  3GTP F;  4JK1 E;  4XLN E;  3GTL F;  1QKL A;  4A93 F;  5E18 E;  1TWA F;  2VUM F;  4KN7 E;  3RZO F;  1HQM E;  4BY1 F;  3GTQ F;  2NVT F;  3S2H F;  4A3E F;  4Y52 F;  1I50 F;  4MEX E;  3S1N F;  2NVQ F;  3HOY F;  1Y1V F;  3WOD E;  4C3J F;  2O5I E;  2E2I F;  4Y7N F;  3CQZ F;  5D4C E;  4OIP E;  4LJZ E;  4YFN E;  3K7A F;  1SFO F;  5TMC E;  4A3M F;  3M3Y F;  4YFX E;  3HKZ K;  1I6V E;  2A68 E;  3I4M F;  4A3L F;  1YNN K;  1Y1W F;  4OIR E;  1ZYR E;  4OIQ E;  5M5W F;  2NVX F;  2O5J E;  5IP9 F;  4Q5S E;  2Y0S I;  1TWH F;  2A6E E;  5IP7 F;  5C44 F;  1I3Q F;  2WAQ K;  4XSZ E;  5FLM F; 
#chains in the Genus database with same CATH topology
 2NVX E;  5IP9 E;  1R9T F;  1TWH E;  4ZH4 E;  5IP7 E;  5C44 E;  5M3M F;  2E2H F;  2R93 F;  4A3K F;  1I3Q E;  1IW7 E;  3S1R F;  5TMF E;  5FLM E;  4BBR F;  3S15 F;  5C3E F;  3HOV F;  1K83 F;  3GTO F;  4XSX E;  3H0G F;  3HOW F;  1R9T E;  2A6H E;  2R93 E;  4YG2 E;  5M3M E;  1TWF F;  2E2H E;  4A3K E;  4MQ9 E;  5IYD F;  3S1R E;  4BXX F;  4C2M F;  5M5Y F;  4BBR E;  2R7Z F;  5C3E E;  3HOV E;  1K83 E;  5M5X F;  3GTO E;  3S15 E;  3HOW E;  3S17 F;  4LK0 E;  2JA7 F;  1TWF E;  4BXX E;  5IYD E;  5D4D E;  2PMZ H;  2PPB E;  4C2M E;  4Q4Z E;  5M5Y E;  2R7Z E;  2JA8 F;  1DZF A;  2NVY F;  5M5X E;  3H3V G;  4MEY E;  2BE5 E;  3S17 E;  4XLP E;  4YFK E;  5C4X F;  3I4N F;  4A3B F;  2A69 E;  2YU9 F;  4LK1 E;  2B63 F;  4AYB H;  3PO2 F;  4A3C F;  1EIK A;  4C3I F;  4G7Z E;  1TWC F;  2JA8 E;  2NVY E;  3DXJ E;  2CW0 E;  3GTM F;  4BY7 F;  1I6H F;  4QIW H;  2JA6 F;  5C4X E;  3RZD F;  4A3F F;  5M3F F;  3I4N E;  4OIO E;  4A3B E;  4X6A F;  2YU9 E;  2B63 E;  4A3C E;  3PO2 E;  4AYB K;  3GTK F;  4C3I E;  2KRX A;  1TWC E;  3GTM E;  4OIN E;  5D4E E;  2Y0S H;  4BY7 E;  3M4O F;  2JA6 E;  4A3D F;  3RZD E;  4A3F E;  3PO3 F;  5M3F E;  4X6A E;  3HOZ F;  1YNJ K;  2WB1 I;  3H0G E;  3GTK E;  5IYB F;  1WCM F;  3FKI F;  3HOU F;  4BBS F;  5C4J F;  4G7H E;  3S2D F;  3M4O E;  4A3D E;  3S1Q F;  3PO3 E;  4G7O E;  3HOZ E;  2E2J F;  5BYH E;  5IYB E;  1WCM E;  2JA7 E;  3GTG F;  3FKI E;  4KN4 E;  3HKZ H;  3HOU E;  1SMY E;  5C4J E;  3S16 F;  4BBS E;  2PMZ K;  3S1Q E;  5FJ8 F;  3S2D E;  4GZY E;  4A3G F;  5E17 E;  2E2J E;  4KMU E;  4C3H F;  2R92 F;  3GTG E;  3S1M F;  3HOX F;  1TWG F;  3S16 E;  4A3G E;  5FJ8 E;  3GTJ F;  5IYC F;  3S14 F;  5IPL E;  3EQL E;  4A3I F;  2JA5 F;  4LLG E;  4A3J F;  3H3V F;  1I6H E;  4C3H E;  2R92 E;  4QIW K;  3GTP F;  4JK1 E;  3S1M E;  3HOX E;  1TWG E;  4XLN E;  3GTL F;  1QKL A;  4A93 F;  5E18 E;  5IYC E;  1TWA F;  3GTJ E;  3S14 E;  4A3I E;  2JA5 E;  2VUM F;  4A3J E;  4KN7 E;  3RZO F;  1HQM E;  3GTP E;  4BY1 F;  3GTL E;  4A93 E;  3GTQ F;  2NVT F;  1TWA E;  2VUM E;  3S2H F;  4A3E F;  4Y52 F;  1I50 F;  4MEX E;  3S1N F;  3RZO E;  2NVQ F;  3HOY F;  1Y1V F;  3WOD E;  4BY1 E;  4C3J F;  2O5I E;  2E2I F;  4Y7N F;  3CQZ F;  5D4C E;  4OIP E;  3GTQ E;  4LJZ E;  4YFN E;  3K7A F;  1SFO F;  2NVT E;  3S2H E;  4A3E E;  5TMC E;  4A3M F;  2WB1 H;  1I50 E;  4YFX E;  3M3Y F;  3HKZ K;  3S1N E;  4Y52 E;  1I6V E;  2A68 E;  2NVQ E;  3HOY E;  1Y1V E;  3I4M F;  4C3J E;  4A3L F;  2E2I E;  2WAQ H;  3CQZ E;  1YNN K;  4Y7N E;  1Y1W F;  4OIR E;  3K7A E;  1SFO E;  1ZYR E;  4OIQ E;  5M5W F;  2NVX F;  4A3M E;  3M3Y E;  5IP9 F;  2O5J E;  4Q5S E;  2Y0S I;  3I4M E;  1TWH F;  2A6E E;  5IP7 F;  5C44 F;  4A3L E;  1I3Q F;  2WAQ K;  4XSZ E;  1Y1W E;  5FLM F;  5M5W E; 
#chains in the Genus database with same CATH homology
 1R9T F;  4ZH4 E;  2R93 F;  5IPL E;  5M3M F;  2E2H F;  4A3K F;  1IW7 E;  3S1R F;  5TMF E;  4BBR F;  3S15 F;  5C3E F;  3HOV F;  1K83 F;  3GTO F;  4XSX E;  3H0G F;  3HOW F;  2A6H E;  4YG2 E;  1TWF F;  4BXX F;  4MQ9 E;  5IYD F;  4C2M F;  5M5Y F;  2R7Z F;  5M5X F;  3S17 F;  4LK0 E;  2JA7 F;  5D4D E;  2PPB E;  4Q4Z E;  2JA8 F;  3H3V G;  2NVY F;  4MEY E;  2BE5 E;  4XLP E;  4YFK E;  5C4X F;  3I4N F;  4A3B F;  2A69 E;  2YU9 F;  4LK1 E;  2B63 F;  4A3C F;  3PO2 F;  4C3I F;  4G7Z E;  1TWC F;  3GTM F;  3DXJ E;  2CW0 E;  4BY7 F;  1I6H F;  2JA6 F;  3RZD F;  4A3F F;  5M3F F;  4X6A F;  4OIO E;  4AYB K;  3GTK F;  2KRX A;  4OIN E;  5D4E E;  3M4O F;  4A3D F;  3PO3 F;  3HOZ F;  1YNJ K;  2WB1 I;  5IYB F;  1WCM F;  3FKI F;  3HOU F;  4BBS F;  5C4J F;  4G7H E;  3S2D F;  3S1Q F;  4G7O E;  2E2J F;  5BYH E;  3GTG F;  4KN4 E;  1SMY E;  3S16 F;  4A3G F;  5E17 E;  2PMZ K;  5FJ8 F;  4GZY E;  4KMU E;  4C3H F;  2R92 F;  3S1M F;  3HOX F;  1TWG F;  3GTJ F;  5IYC F;  3S14 F;  3EQL E;  4A3I F;  2JA5 F;  4LLG E;  4A3J F;  4QIW K;  3GTP F;  4JK1 E;  4XLN E;  3GTL F;  1QKL A;  4A93 F;  5E18 E;  1TWA F;  2VUM F;  4KN7 E;  3RZO F;  1HQM E;  4BY1 F;  3GTQ F;  2NVT F;  3S2H F;  4A3E F;  4Y52 F;  1I50 F;  4MEX E;  3S1N F;  2NVQ F;  3HOY F;  1Y1V F;  3WOD E;  4C3J F;  2O5I E;  2E2I F;  4Y7N F;  3CQZ F;  5D4C E;  4OIP E;  4LJZ E;  4YFN E;  3K7A F;  1SFO F;  5TMC E;  4A3M F;  3M3Y F;  4YFX E;  3HKZ K;  1I6V E;  2A68 E;  3I4M F;  4A3L F;  1YNN K;  1Y1W F;  4OIR E;  1ZYR E;  4OIQ E;  5M5W F;  2NVX F;  2O5J E;  5IP9 F;  4Q5S E;  2Y0S I;  1TWH F;  2A6E E;  5IP7 F;  5C44 F;  1I3Q F;  2WAQ K;  4XSZ E;  5FLM F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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