2E2JF

Rna polymerase ii elongation complex in 5 mm mg+2 with gmpcpp
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
86
structure length
86
Chain Sequence
LKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(P*AP*UP*CP*GP*AP*GP*AP*GP*G)-3'
total genus 16
structure length 86
sequence length 86
ec nomenclature
pdb deposition date 2006-11-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 2e2jF00
2CW0E 4A3BF 1I3QF 1I6VE 4Q4ZE 5M5XF 5C3EF 3GTPF 4A3CF 2WAQK 4C3JF 5C4JF 4C3HF 2NVYF 4XLNE 4A3FF 1YNNK 4YFXE 3CQZF 5D4CE 5TMFE 4BY7F 2VUMF 3HKZK 5D4EE 3S16F 2E2IF 4OIQE 5D4DE 4OINE 3I4NF 1HQME 4KMUE 1SFOF 2JA7F 3S14F 1TWHF 4XSXE 3HOUF 3RZOF 3FKIF 1R9TF 4G7HE 1TWAF 5E18E 3HOZF 2PMZK 3S15F 2R93F 1Y1WF 4XSZE 5C44F 4Y7NF 4BXXF 5M3FF 4A93F 4GZYE 4KN4E 3GTJF 4A3LF 2O5JE 4C3IF 3PO2F 3GTGF 5FLMF 4LJZE 3EQLE 3HOYF 5IYDF 3S1QF 1TWFF 3HOXF 3S1MF 4Y52F 2O5IE 2A69E 3M3YF 2Y0SI 5E17E 3H0GF 2JA8F 3WODE 1K83F 4YFKE 5IYCF 4YG2E 5IPLE 1TWGF 4BBRF 1SMYE 4LLGE 3GTOF 2E2JF 3S17F 1I6HF 3PO3F 2R7ZF 4MEYE 3S2HF 4LK0E 3M4OF 4A3GF 2WB1I 4G7ZE 4MQ9E 5IYBF 1TWCF 4KN7E 1I50F 4ZH4E 2E2HF 3GTMF 4JK1E 4A3KF 3GTQF 1YNJK 1ZYRE 3S1RF 4OIRE 5BYHE 2YU9F 2JA6F 5M3MF 4AYBK 2A6EE 4A3IF 3RZDF 2R92F 1QKLA 4A3EF 1WCMF 4OIPE 2JA5F 3DXJE 4BBSF 4BY1F 4C2MF 4A3DF 5TMCE 2NVXF 4XLPE 3GTLF 5C4XF 4G7OE 4A3MF 3S1NF 2A6HE 5FJ8F 4A3JF 5M5YF 5IP9F 3HOVF 4X6AF 2NVQF 2BE5E 3H3VG 3S2DF 4OIOE 5IP7F 2B63F 5M5WF 2PPBE 2A68E 1IW7E 2NVTF 3K7AF 4Q5SE 4YFNE 3HOWF 4MEXE 1Y1VF 3GTKF 3I4MF 4LK1E
chains in the Genus database with same CATH superfamily
1I3QE 2CW0E 4A3BF 4AYBH 1I3QF 4A93E 5M5XE 1I6VE 3GTPE 4Q4ZE 5M5XF 4C3JE 5C3EF 3GTPF 3GTJE 2WAQK 4C3JF 4A3LE 5C4JF 4A3CF 4C3IE 4C3HF 2NVYF 4XLNE 3GTGE 5FLME 4A3FE 3CQZE 4A3FF 1YNNK 4YFXE 3CQZF 3HOYE 5D4CE 5TMFE 4BY7F 3HOXE 3HKZK 5D4EE 2VUMF 3S16F 2E2IF 4OIQE 5D4DE 4OINE 3I4NE 4Y52E 3I4NF 1HQME 3M3YE 4KMUE 1SFOF 1TWHE 2JA7F 3HOUE 3S14F 1TWHF 4XSXE 3HOUF 1R9TE 3RZOF 3FKIF 1R9TF 1TWAE 4G7HE 1TWAF 1TWGE 4BBRE 2PMZK 5E18E 1Y1WE 3HOZF 3S15F 2R93F 5C44E 4XSZE 4Y7NE 1Y1WF 4BXXE 5C44F 4Y7NF 5M3FE 4BXXF 3S17E 5M3FF 4A93F 4GZYE 4KN4E 3GTJF 4A3LF 2O5JE 2WAQH 4C3IF 3PO2E 3PO2F 5IYBE 3GTGF 5FLMF 4LJZE 3EQLE 5IYDE 3S1QE 1TWFE 3HOYF 4A3KE 5IYDF 3S1QF 1TWFF 3HOXF 3S1ME 3S1RE 2YU9E 3HKZH 3S1MF 4Y52F 2O5IE 4X6AF 2A69E 3M3YF 2Y0SI 5E17E 2R92E 3H0GE 4A3EE 1K83E 2JA8E 5IYCE 3H0GF 2JA5E 1K83F 3WODE 4YFKE 5IYCF 2JA8F 4YG2E 5IPLE 4BY1E 1TWGF 4BBRF 1SMYE 4LLGE 2NVXE 2PMZH 3GTOE 1DZFA 2E2JE 3GTOF 1I6HE 2E2JF 3S17F 5C4XE 1I6HF 4A3ME 3PO3E 2R7ZE 3PO3F 3S2HE 2R7ZF 5FJ8E 4MEYE 3S2HF 3M4OE 4LK0E 4A3GE 4QIWK 3HOVE 3M4OF 4A3GF 2WB1I 1TWCE 4G7ZE 4MQ9E 2Y0SH 5IYBF 1TWCF 4KN7E 5M5WE 1I50E 2E2HE 3GTME 1I50F 4ZH4E 2E2HF 2NVTE 4JK1E 4A3KF 3GTMF 3GTQF 1YNJK 3GTQE 1ZYRE 2JA6E 3S1RF 5M3ME 4OIRE 1Y1VE 5BYHE 2YU9F 2JA6F 5M3MF 3I4ME 4A3IE 4AYBK 3RZDE 2A6EE 4A3IF 4A3BE 3RZDF 1WCME 2R92F 1QKLA 4A3EF 1EIKA 1WCMF 4OIPE 2JA5F 4BBSE 3H3VF 3DXJE 5C3EE 4A3CE 4BBSF 4C2ME 5C4JE 2WB1H 4A3DE 4C3HE 4BY1F 4C2MF 4A3DF 2NVYE 5TMCE 2NVXF 4XLPE 3GTLE 3GTLF 3S1NE 2KRXA 4G7OE 5C4XF 4A3MF 3S1NF 4BY7E 4A3JE 2A6HE 5M5YE 5FJ8F 5IP9E 4A3JF 2VUME 5M5YF 2NVQE 3S16E 5IP9F 2E2IE 3HOVF 2NVQF 2BE5E 3H3VG 3S2DF 3S2DE 4QIWH 4X6AE 5IP7E 2B63E 4OIOE 5IP7F 2B63F 5M5WF 1SFOE 2PPBE 2JA7E 2A68E 3S14E 3K7AE 1IW7E 2NVTF 3RZOE 3FKIE 3K7AF 3HOWE 4Q5SE 4YFNE 3HOWF 3HOZE 3S15E 4MEXE 1Y1VF 3GTKE 2R93E 3GTKF 3I4MF 4LK1E
chains in the Genus database with same CATH topology
2CW0E 4A3BF 1I3QF 1I6VE 4Q4ZE 5M5XF 5C3EF 3GTPF 4A3CF 2WAQK 4C3JF 5C4JF 4C3HF 2NVYF 4XLNE 4A3FF 1YNNK 4YFXE 3CQZF 5D4CE 5TMFE 4BY7F 2VUMF 3HKZK 5D4EE 3S16F 2E2IF 4OIQE 5D4DE 4OINE 3I4NF 1HQME 4KMUE 1SFOF 2JA7F 3S14F 1TWHF 4XSXE 3HOUF 3RZOF 3FKIF 1R9TF 4G7HE 1TWAF 5E18E 3HOZF 2PMZK 3S15F 2R93F 1Y1WF 4XSZE 5C44F 4Y7NF 4BXXF 5M3FF 4A93F 4GZYE 4KN4E 3GTJF 4A3LF 2O5JE 4C3IF 3PO2F 3GTGF 5FLMF 4LJZE 3EQLE 3HOYF 5IYDF 3S1QF 1TWFF 3HOXF 3S1MF 4Y52F 2O5IE 2A69E 3M3YF 2Y0SI 5E17E 3H0GF 2JA8F 3WODE 1K83F 4YFKE 5IYCF 4YG2E 5IPLE 1TWGF 4BBRF 1SMYE 4LLGE 3GTOF 2E2JF 3S17F 1I6HF 3PO3F 2R7ZF 4MEYE 3S2HF 4LK0E 4QIWK 3M4OF 4A3GF 2WB1I 4G7ZE 4MQ9E 5IYBF 1TWCF 4KN7E 1I50F 4ZH4E 2E2HF 3GTMF 4JK1E 4A3KF 3GTQF 1YNJK 1ZYRE 3S1RF 4OIRE 5BYHE 2YU9F 2JA6F 5M3MF 4AYBK 2A6EE 4A3IF 3RZDF 2R92F 1QKLA 4A3EF 1WCMF 4OIPE 2JA5F 3DXJE 4BBSF 4BY1F 4C2MF 4A3DF 5TMCE 2NVXF 4XLPE 3GTLF 2KRXA 4G7OE 5C4XF 4A3MF 3S1NF 2A6HE 5FJ8F 4A3JF 5M5YF 5IP9F 3HOVF 4X6AF 2NVQF 2BE5E 3H3VG 3S2DF 4OIOE 5IP7F 2B63F 5M5WF 2PPBE 2A68E 1IW7E 2NVTF 3K7AF 4Q5SE 4YFNE 3HOWF 4MEXE 1Y1VF 3GTKF 3I4MF 4LK1E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2CW0 E;  4A3B F;  1I3Q F;  1I6V E;  4Q4Z E;  5M5X F;  5C3E F;  3GTP F;  4A3C F;  2WAQ K;  4C3J F;  5C4J F;  4C3H F;  2NVY F;  4XLN E;  4A3F F;  1YNN K;  4YFX E;  3CQZ F;  5D4C E;  5TMF E;  4BY7 F;  2VUM F;  3HKZ K;  5D4E E;  3S16 F;  2E2I F;  4OIQ E;  5D4D E;  4OIN E;  3I4N F;  1HQM E;  4KMU E;  1SFO F;  2JA7 F;  3S14 F;  1TWH F;  4XSX E;  3HOU F;  3RZO F;  3FKI F;  1R9T F;  4G7H E;  1TWA F;  5E18 E;  3HOZ F;  2PMZ K;  3S15 F;  2R93 F;  1Y1W F;  4XSZ E;  5C44 F;  4Y7N F;  4BXX F;  5M3F F;  4A93 F;  4GZY E;  4KN4 E;  3GTJ F;  4A3L F;  2O5J E;  4C3I F;  3PO2 F;  3GTG F;  5FLM F;  4LJZ E;  3EQL E;  3HOY F;  5IYD F;  3S1Q F;  1TWF F;  3HOX F;  3S1M F;  4Y52 F;  2O5I E;  2A69 E;  3M3Y F;  2Y0S I;  5E17 E;  3H0G F;  2JA8 F;  3WOD E;  1K83 F;  4YFK E;  5IYC F;  4YG2 E;  5IPL E;  1TWG F;  4BBR F;  1SMY E;  4LLG E;  3GTO F;  2E2J F;  3S17 F;  1I6H F;  3PO3 F;  2R7Z F;  4MEY E;  3S2H F;  4LK0 E;  3M4O F;  4A3G F;  2WB1 I;  4G7Z E;  4MQ9 E;  5IYB F;  1TWC F;  4KN7 E;  1I50 F;  4ZH4 E;  2E2H F;  3GTM F;  4JK1 E;  4A3K F;  3GTQ F;  1YNJ K;  1ZYR E;  3S1R F;  4OIR E;  5BYH E;  2YU9 F;  2JA6 F;  5M3M F;  4AYB K;  2A6E E;  4A3I F;  3RZD F;  2R92 F;  1QKL A;  4A3E F;  1WCM F;  4OIP E;  2JA5 F;  3DXJ E;  4BBS F;  4BY1 F;  4C2M F;  4A3D F;  5TMC E;  2NVX F;  4XLP E;  3GTL F;  5C4X F;  4G7O E;  4A3M F;  3S1N F;  2A6H E;  5FJ8 F;  4A3J F;  5M5Y F;  5IP9 F;  3HOV F;  4X6A F;  2NVQ F;  2BE5 E;  3H3V G;  3S2D F;  4OIO E;  5IP7 F;  2B63 F;  5M5W F;  2PPB E;  2A68 E;  1IW7 E;  2NVT F;  3K7A F;  4Q5S E;  4YFN E;  3HOW F;  4MEX E;  1Y1V F;  3GTK F;  3I4M F;  4LK1 E; 
#chains in the Genus database with same CATH topology
 1I3Q E;  2CW0 E;  4A3B F;  4AYB H;  1I3Q F;  4A93 E;  5M5X E;  1I6V E;  3GTP E;  4Q4Z E;  5M5X F;  4C3J E;  5C3E F;  3GTP F;  3GTJ E;  2WAQ K;  4C3J F;  4A3L E;  5C4J F;  4A3C F;  4C3I E;  4C3H F;  2NVY F;  4XLN E;  3GTG E;  5FLM E;  4A3F E;  3CQZ E;  4A3F F;  1YNN K;  4YFX E;  3CQZ F;  3HOY E;  5D4C E;  5TMF E;  4BY7 F;  3HOX E;  3HKZ K;  5D4E E;  2VUM F;  3S16 F;  2E2I F;  4OIQ E;  5D4D E;  4OIN E;  3I4N E;  4Y52 E;  3I4N F;  1HQM E;  3M3Y E;  4KMU E;  1SFO F;  1TWH E;  2JA7 F;  3HOU E;  3S14 F;  1TWH F;  4XSX E;  3HOU F;  1R9T E;  3RZO F;  3FKI F;  1R9T F;  1TWA E;  4G7H E;  1TWA F;  1TWG E;  4BBR E;  2PMZ K;  5E18 E;  1Y1W E;  3HOZ F;  3S15 F;  2R93 F;  5C44 E;  4XSZ E;  4Y7N E;  1Y1W F;  4BXX E;  5C44 F;  4Y7N F;  5M3F E;  4BXX F;  3S17 E;  5M3F F;  4A93 F;  4GZY E;  4KN4 E;  3GTJ F;  4A3L F;  2O5J E;  2WAQ H;  4C3I F;  3PO2 E;  3PO2 F;  5IYB E;  3GTG F;  5FLM F;  4LJZ E;  3EQL E;  5IYD E;  3S1Q E;  1TWF E;  3HOY F;  4A3K E;  5IYD F;  3S1Q F;  1TWF F;  3HOX F;  3S1M E;  3S1R E;  2YU9 E;  3HKZ H;  3S1M F;  4Y52 F;  2O5I E;  4X6A F;  2A69 E;  3M3Y F;  2Y0S I;  5E17 E;  2R92 E;  3H0G E;  4A3E E;  1K83 E;  2JA8 E;  5IYC E;  3H0G F;  2JA5 E;  1K83 F;  3WOD E;  4YFK E;  5IYC F;  2JA8 F;  4YG2 E;  5IPL E;  4BY1 E;  1TWG F;  4BBR F;  1SMY E;  4LLG E;  2NVX E;  2PMZ H;  3GTO E;  1DZF A;  2E2J E;  3GTO F;  1I6H E;  2E2J F;  3S17 F;  5C4X E;  1I6H F;  4A3M E;  3PO3 E;  2R7Z E;  3PO3 F;  3S2H E;  2R7Z F;  5FJ8 E;  4MEY E;  3S2H F;  3M4O E;  4LK0 E;  4A3G E;  4QIW K;  3HOV E;  3M4O F;  4A3G F;  2WB1 I;  1TWC E;  4G7Z E;  4MQ9 E;  2Y0S H;  5IYB F;  1TWC F;  4KN7 E;  5M5W E;  1I50 E;  2E2H E;  3GTM E;  1I50 F;  4ZH4 E;  2E2H F;  2NVT E;  4JK1 E;  4A3K F;  3GTM F;  3GTQ F;  1YNJ K;  3GTQ E;  1ZYR E;  2JA6 E;  3S1R F;  5M3M E;  4OIR E;  1Y1V E;  5BYH E;  2YU9 F;  2JA6 F;  5M3M F;  3I4M E;  4A3I E;  4AYB K;  3RZD E;  2A6E E;  4A3I F;  4A3B E;  3RZD F;  1WCM E;  2R92 F;  1QKL A;  4A3E F;  1EIK A;  1WCM F;  4OIP E;  2JA5 F;  4BBS E;  3H3V F;  3DXJ E;  5C3E E;  4A3C E;  4BBS F;  4C2M E;  5C4J E;  2WB1 H;  4A3D E;  4C3H E;  4BY1 F;  4C2M F;  4A3D F;  2NVY E;  5TMC E;  2NVX F;  4XLP E;  3GTL E;  3GTL F;  3S1N E;  2KRX A;  4G7O E;  5C4X F;  4A3M F;  3S1N F;  4BY7 E;  4A3J E;  2A6H E;  5M5Y E;  5FJ8 F;  5IP9 E;  4A3J F;  2VUM E;  5M5Y F;  2NVQ E;  3S16 E;  5IP9 F;  2E2I E;  3HOV F;  2NVQ F;  2BE5 E;  3H3V G;  3S2D F;  3S2D E;  4QIW H;  4X6A E;  5IP7 E;  2B63 E;  4OIO E;  5IP7 F;  2B63 F;  5M5W F;  1SFO E;  2PPB E;  2JA7 E;  2A68 E;  3S14 E;  3K7A E;  1IW7 E;  2NVT F;  3RZO E;  3FKI E;  3K7A F;  3HOW E;  4Q5S E;  4YFN E;  3HOW F;  3HOZ E;  3S15 E;  4MEX E;  1Y1V F;  3GTK E;  2R93 E;  3GTK F;  3I4M F;  4LK1 E; 
#chains in the Genus database with same CATH homology
 2CW0 E;  4A3B F;  1I3Q F;  1I6V E;  4Q4Z E;  5M5X F;  5C3E F;  3GTP F;  4A3C F;  2WAQ K;  4C3J F;  5C4J F;  4C3H F;  2NVY F;  4XLN E;  4A3F F;  1YNN K;  4YFX E;  3CQZ F;  5D4C E;  5TMF E;  4BY7 F;  2VUM F;  3HKZ K;  5D4E E;  3S16 F;  2E2I F;  4OIQ E;  5D4D E;  4OIN E;  3I4N F;  1HQM E;  4KMU E;  1SFO F;  2JA7 F;  3S14 F;  1TWH F;  4XSX E;  3HOU F;  3RZO F;  3FKI F;  1R9T F;  4G7H E;  1TWA F;  5E18 E;  3HOZ F;  2PMZ K;  3S15 F;  2R93 F;  1Y1W F;  4XSZ E;  5C44 F;  4Y7N F;  4BXX F;  5M3F F;  4A93 F;  4GZY E;  4KN4 E;  3GTJ F;  4A3L F;  2O5J E;  4C3I F;  3PO2 F;  3GTG F;  5FLM F;  4LJZ E;  3EQL E;  3HOY F;  5IYD F;  3S1Q F;  1TWF F;  3HOX F;  3S1M F;  4Y52 F;  2O5I E;  2A69 E;  3M3Y F;  2Y0S I;  5E17 E;  3H0G F;  2JA8 F;  3WOD E;  1K83 F;  4YFK E;  5IYC F;  4YG2 E;  5IPL E;  1TWG F;  4BBR F;  1SMY E;  4LLG E;  3GTO F;  2E2J F;  3S17 F;  1I6H F;  3PO3 F;  2R7Z F;  4MEY E;  3S2H F;  4LK0 E;  4QIW K;  3M4O F;  4A3G F;  2WB1 I;  4G7Z E;  4MQ9 E;  5IYB F;  1TWC F;  4KN7 E;  1I50 F;  4ZH4 E;  2E2H F;  3GTM F;  4JK1 E;  4A3K F;  3GTQ F;  1YNJ K;  1ZYR E;  3S1R F;  4OIR E;  5BYH E;  2YU9 F;  2JA6 F;  5M3M F;  4AYB K;  2A6E E;  4A3I F;  3RZD F;  2R92 F;  1QKL A;  4A3E F;  1WCM F;  4OIP E;  2JA5 F;  3DXJ E;  4BBS F;  4BY1 F;  4C2M F;  4A3D F;  5TMC E;  2NVX F;  4XLP E;  3GTL F;  2KRX A;  4G7O E;  5C4X F;  4A3M F;  3S1N F;  2A6H E;  5FJ8 F;  4A3J F;  5M5Y F;  5IP9 F;  3HOV F;  4X6A F;  2NVQ F;  2BE5 E;  3H3V G;  3S2D F;  4OIO E;  5IP7 F;  2B63 F;  5M5W F;  2PPB E;  2A68 E;  1IW7 E;  2NVT F;  3K7A F;  4Q5S E;  4YFN E;  3HOW F;  4MEX E;  1Y1V F;  3GTK F;  3I4M F;  4LK1 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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