2IQ1A

Crystal structure of human ppm1k
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
260
structure length
257
Chain Sequence
ISLENVGCASQIGKRKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMDLLPKEKNLETLLTLAFLEIDKAFSSHARLATLLTSGTTATVALLRDGIELVVASVGDSRAILCRKGKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKLHHADDSFLVLTTDGINFMVNSQEICDFVNQCHDPNEAAHAVTEQAIQYGTEDNSTAVVVPFGAW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural genomics of protein phosphatases
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Protein phosphatase 2C kappa, PPM1K
total genus 87
structure length 257
sequence length 260
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2006-10-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00481 PP2C Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2iq1A00
4RAFA 4RA2A 5JO2B 3FXMA 3W40A 3W41A 2P8EA 3UJKA 4OICB 3FXKA 3FXLA 4YZHA 3UJLB 3T9QA 4YZGA 5ITIA 3NMNB 3KB3B 4DA1A 2IQ1A 2I44A 3QN1B 5D2UA 4RAGA 2XZVA 3FXJA 3FXOA 3EQ2A 3UJGB 3RNRA 3ZVUB 3JRQA 3W44A 3W42A 3F79A 3D8KA 4LA7B 2V06A 1A6QA 4N0GA 4WVOB 4LG5B 2J86A 2JFRA 3N3CA 3NMVB 2JFTA 3ZT9A 4JNDA 2I0OA 2POPA 5F1MA 3KE6A 3KDJB 3NMTB 2POMA 3W43A 3RT0A 2J4OA 2ISNA 1TXOA 3PU9A 2CM1A 2JFSA 2Y09A 4LGAB 3ES2A 4LGBB 2J82A 3MQ3A 4DS8B 3T91A 5JO1B 3W45A 2IRMA 2PK0A 2PNQA
chains in the Genus database with same CATH superfamily
4RAFA 4RA2A 5JO2B 3FXMA 3W40A 3W41A 2P8EA 3UJKA 4OICB 3FXKA 3FXLA 4YZHA 3UJLB 3T9QA 4YZGA 5ITIA 3NMNB 3KB3B 4DA1A 2IQ1A 2I44A 3QN1B 5D2UA 4RAGA 2XZVA 3FXJA 3FXOA 3EQ2A 3UJGB 3RNRA 3ZVUB 3JRQA 3W44A 3W42A 3F79A 3D8KA 4LA7B 2V06A 4IIKA 1A6QA 4N0GA 4WVOB 4LG5B 2J86A 2JFRA 3N3CA 3NMVB 2JFTA 3ZT9A 4IIPA 4JNDA 2I0OA 2POPA 5F1MA 3KE6A 3KDJB 3NMTB 2POMA 3W43A 3RT0A 2J4OA 2ISNA 1TXOA 3PU9A 2CM1A 2JFSA 2Y09A 4LGAB 3ES2A 4LGBB 2J82A 3MQ3A 4DS8B 3T91A 5JO1B 3W45A 2IRMA 2PK0A 2PNQA
chains in the Genus database with same CATH topology
4RAFA 4RA2A 5JO2B 3FXMA 3W40A 3W41A 2P8EA 3UJKA 4OICB 3FXKA 3FXLA 4YZHA 3UJLB 3T9QA 4YZGA 5ITIA 3NMNB 3KB3B 4DA1A 2IQ1A 2I44A 3QN1B 5D2UA 4RAGA 2XZVA 3FXJA 3FXOA 3EQ2A 3UJGB 3RNRA 3ZVUB 3JRQA 3W44A 3W42A 3F79A 3D8KA 4LA7B 2V06A 1A6QA 4N0GA 4WVOB 4LG5B 2J86A 2JFRA 3N3CA 3NMVB 2JFTA 3ZT9A 4JNDA 2I0OA 2POPA 5F1MA 3KE6A 3KDJB 3NMTB 2POMA 3W43A 3RT0A 2J4OA 2ISNA 1TXOA 3PU9A 2CM1A 2JFSA 2Y09A 4LGAB 3ES2A 4LGBB 2J82A 3MQ3A 4DS8B 3T91A 5JO1B 3W45A 2IRMA 2PK0A 2PNQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RAF A;  4RA2 A;  5JO2 B;  3FXM A;  3W40 A;  3W41 A;  2P8E A;  3UJK A;  4OIC B;  3FXK A;  3FXL A;  4YZH A;  3UJL B;  3T9Q A;  4YZG A;  5ITI A;  3NMN B;  3KB3 B;  4DA1 A;  2IQ1 A;  2I44 A;  3QN1 B;  5D2U A;  4RAG A;  2XZV A;  3FXJ A;  3FXO A;  3EQ2 A;  3UJG B;  3RNR A;  3ZVU B;  3JRQ A;  3W44 A;  3W42 A;  3F79 A;  3D8K A;  4LA7 B;  2V06 A;  1A6Q A;  4N0G A;  4WVO B;  4LG5 B;  2J86 A;  2JFR A;  3N3C A;  3NMV B;  2JFT A;  3ZT9 A;  4JND A;  2I0O A;  2POP A;  5F1M A;  3KE6 A;  3KDJ B;  3NMT B;  2POM A;  3W43 A;  3RT0 A;  2J4O A;  2ISN A;  1TXO A;  3PU9 A;  2CM1 A;  2JFS A;  2Y09 A;  4LGA B;  3ES2 A;  4LGB B;  2J82 A;  3MQ3 A;  4DS8 B;  3T91 A;  5JO1 B;  3W45 A;  2IRM A;  2PK0 A;  2PNQ A; 
#chains in the Genus database with same CATH topology
 4RAF A;  4RA2 A;  5JO2 B;  3FXM A;  3W40 A;  3W41 A;  2P8E A;  3UJK A;  4OIC B;  3FXK A;  3FXL A;  4YZH A;  3UJL B;  3T9Q A;  4YZG A;  5ITI A;  3NMN B;  3KB3 B;  4DA1 A;  2IQ1 A;  2I44 A;  3QN1 B;  5D2U A;  4RAG A;  2XZV A;  3FXJ A;  3FXO A;  3EQ2 A;  3UJG B;  3RNR A;  3ZVU B;  3JRQ A;  3W44 A;  3W42 A;  3F79 A;  3D8K A;  4LA7 B;  2V06 A;  4IIK A;  1A6Q A;  4N0G A;  4WVO B;  4LG5 B;  2J86 A;  2JFR A;  3N3C A;  3NMV B;  2JFT A;  3ZT9 A;  4IIP A;  4JND A;  2I0O A;  2POP A;  5F1M A;  3KE6 A;  3KDJ B;  3NMT B;  2POM A;  3W43 A;  3RT0 A;  2J4O A;  2ISN A;  1TXO A;  3PU9 A;  2CM1 A;  2JFS A;  2Y09 A;  4LGA B;  3ES2 A;  4LGB B;  2J82 A;  3MQ3 A;  4DS8 B;  3T91 A;  5JO1 B;  3W45 A;  2IRM A;  2PK0 A;  2PNQ A; 
#chains in the Genus database with same CATH homology
 4RAF A;  4RA2 A;  5JO2 B;  3FXM A;  3W40 A;  3W41 A;  2P8E A;  3UJK A;  4OIC B;  3FXK A;  3FXL A;  4YZH A;  3UJL B;  3T9Q A;  4YZG A;  5ITI A;  3NMN B;  3KB3 B;  4DA1 A;  2IQ1 A;  2I44 A;  3QN1 B;  5D2U A;  4RAG A;  2XZV A;  3FXJ A;  3FXO A;  3EQ2 A;  3UJG B;  3RNR A;  3ZVU B;  3JRQ A;  3W44 A;  3W42 A;  3F79 A;  3D8K A;  4LA7 B;  2V06 A;  1A6Q A;  4N0G A;  4WVO B;  4LG5 B;  2J86 A;  2JFR A;  3N3C A;  3NMV B;  2JFT A;  3ZT9 A;  4JND A;  2I0O A;  2POP A;  5F1M A;  3KE6 A;  3KDJ B;  3NMT B;  2POM A;  3W43 A;  3RT0 A;  2J4O A;  2ISN A;  1TXO A;  3PU9 A;  2CM1 A;  2JFS A;  2Y09 A;  4LGA B;  3ES2 A;  4LGB B;  2J82 A;  3MQ3 A;  4DS8 B;  3T91 A;  5JO1 B;  3W45 A;  2IRM A;  2PK0 A;  2PNQ A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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