2JA5E

Cpd lesion containing rna polymerase ii elongation complex a
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Cpd Damage Recognition by Transcribing RNA Polymerase II
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 48
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2006-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 2ja5E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 2ja5E02
2R92E 3GTME 3GTKE 4A3KE 1EIKA 5M5XE 5FJ8E 3HOVE 1SFOE 3S1ME 5FLME 1I6HE 3FKIE 3HOWE 4A3FE 2E2IE 3M4OE 3S1QE 5C44E 5C4XE 5IYBE 3GTJE 3HOXE 4BY1E 4A3IE 3HKZH 3HOUE 3HOYE 5IYDE 1TWCE 5M5WE 3H0GE 2NVQE 4A3BE 4A3EE 2JA5E 3PO2E 4QIWH 1Y1VE 5M5YE 3GTOE 2NVXE 3RZDE 4C3IE 1DZFA 3GTLE 3PO3E 4Y7NE 3S1RE 4BXXE 5C4JE 2WB1H 1K83E 5C3EE 1WCME 4A3GE 2JA7E 4A3JE 2JA6E 4A93E 2Y0SH 3GTQE 5M3ME 3I4NE 5IYCE 1Y1WE 1I3QE 3M3YE 1TWHE 4BBRE 4C3HE 3GTGE 3I4ME 2VUME 4A3DE 4Y52E 1R9TE 2NVYE 2R7ZE 2JA8E 3S17E 2YU9E 3S14E 3S2HE 2E2JE 2B63E 3GTPE 4A3ME 5M3FE 4X6AE 4A3LE 3CQZE 2PMZH 2WAQH 4A3CE 1I50E 4BY7E 5IP7E 3S15E 3S1NE 3S16E 2R93E 4AYBH 5IP9E 1TWGE 2NVTE 3RZOE 3H3VF 1TWAE 4C2ME 3K7AE 4BBSE 1TWFE 3S2DE 4C3JE 3HOZE 2E2HE
chains in the Genus database with same CATH superfamily
5C4JF 2R92E 4YFNE 3GTME 3GTKE 4A3KE 1QKLA 4XLPE 5C3EF 1EIKA 1WCMF 4MQ9E 3HOUF 4KN7E 4LK0E 5M5XE 3HOYF 5FJ8E 3HOVE 1SFOE 2JA7F 3S1ME 5IYDF 5FLME 1I6HE 5M5WF 3H0GF 3FKIE 3HOWE 5C44F 4A3FE 2E2IE 5D4EE 4A3EF 3M4OE 3S1QE 2PMZK 1Y1VF 5C44E 5C4XE 5M5YF 3GTOF 5IYBE 3I4NF 3GTJE 4G7ZE 3HOXE 4BY1E 4MEXE 5IPLE 5TMFE 2NVXF 3RZDF 4XLNE 3DXJE 4A3IE 3HKZH 3HOUE 4YFKE 4LK1E 3WODE 2KRXA 3HOYE 5D4DE 3PO3F 4C3HF 4Y7NF 5E18E 5IYDE 2A69E 4OIPE 1TWCE 3S1RF 2WB1I 2VUMF 3GTGF 5M5WE 3H0GE 1R9TF 3I4MF 2R7ZF 2NVQE 4A3BE 2JA8F 4A3EE 2JA5E 3PO2E 4QIWH 1Y1VE 2YU9F 1K83F 5M5YE 3GTOE 4QIWK 2E2JF 2O5JE 4A3GF 4MEYE 4G7HE 4ZH4E 1SMYE 2A6EE 4KN4E 2NVXE 3RZDE 1YNJK 2Y0SI 4A3JF 4A3MF 3GTPF 2JA6F 2A6HE 4C3IE 4A93F 1DZFA 4X6AF 3GTQF 3GTLE 4YG2E 3PO3E 4LLGE 4OIRE 4Y7NE 3S1RE 4BXXE 1I50F 5M3MF 5IYCF 5IP7F 5C4JE 2WB1H 2R93F 1Y1WF 1K83E 2O5IE 5C3EE 1I3QF 3M3YF 1WCME 2BE5E 4A3GE 2NVTF 1TWHF 3H3VG 3RZOF 4BBRF 1YNNK 3HKZK 4BXXF 2PPBE 2JA7E 4C2MF 3K7AF 4OIQE 4BBSF 1TWFF 3EQLE 4Y52F 4A3DF 4YFXE 4A3JE 2NVYF 5TMCE 2JA6E 4A93E 1HQME 3S17F 5BYHE 2Y0SH 3GTQE 4C3JF 3S14F 3S2HF 4JK1E 2E2HF 5M3ME 3I4NE 5IYCE 5D4CE 2B63F 4Q4ZE 2CW0E 4XSXE 1Y1WE 1I3QE 3M3YE 5M3FF 4GZYE 3S1MF 1TWHE 4A3LF 4BBRE 3CQZF 1I6HF 4C3HE 3HOWF 4A3CF 3GTGE 4KMUE 3I4ME 2VUME 4A3DE 4Y52E 2A68E 4BY7F 1R9TE 4Q5SE 4LJZE 2NVYE 2R7ZE 2JA8E 3S17E 5IYBF 4OIOE 3S16F 3S15F 3S1NF 5C4XF 2YU9E 5IP9F 3S14E 3S2HE 2E2JE 1TWGF 3HOXF 4G7OE 1TWAF 2B63E 4A3IF 3GTPE 4A3ME 3S2DF 5M3FE 4X6AE 4A3LE 1TWCF 3CQZE 2PMZH 2WAQH 4A3CE 3HOZF 2NVQF 4XSZE 2R92F 4A3BF 1I50E 2JA5F 3GTMF 4BY7E 5IP7E 2WAQK 4A3KF 3GTKF 3S15E 3PO2F 3S1NE 3S16E 2R93E 4AYBH 5IP9E 5M5XF 3M4OF 1TWGE 4AYBK 2NVTE 5FJ8F 3RZOE 1SFOF 1IW7E 3H3VF 5FLMF 1ZYRE 3HOVF 1I6VE 1TWAE 3FKIF 4A3FF 2E2IF 4C2ME 3K7AE 4BBSE 4C3IF 1TWFE 3S1QF 3GTLF 3S2DE 4OINE 3GTJF 4C3JE 5E17E 4BY1F 3HOZE 2E2HE
chains in the Genus database with same CATH topology
2R92E 3GTME 3GTKE 4A3KE 1EIKA 5M5XE 5FJ8E 3HOVE 1SFOE 3S1ME 5FLME 1I6HE 3FKIE 3HOWE 4A3FE 2E2IE 3M4OE 3S1QE 5C44E 5C4XE 5IYBE 3GTJE 3HOXE 4BY1E 4A3IE 3HKZH 3HOUE 3HOYE 5IYDE 1TWCE 5M5WE 3H0GE 2NVQE 4A3BE 4A3EE 2JA5E 3PO2E 4QIWH 1Y1VE 5M5YE 3GTOE 2NVXE 3RZDE 4C3IE 1DZFA 3GTLE 3PO3E 4Y7NE 3S1RE 4BXXE 5C4JE 2WB1H 1K83E 5C3EE 1WCME 4A3GE 2JA7E 4A3JE 2JA6E 4A93E 2Y0SH 3GTQE 5M3ME 3I4NE 5IYCE 1Y1WE 1I3QE 3M3YE 1TWHE 4BBRE 4C3HE 3GTGE 3I4ME 2VUME 4A3DE 4Y52E 1R9TE 2NVYE 2R7ZE 2JA8E 3S17E 2YU9E 3S14E 3S2HE 2E2JE 2B63E 3GTPE 4A3ME 5M3FE 4X6AE 4A3LE 3CQZE 2PMZH 2WAQH 4A3CE 1I50E 4BY7E 5IP7E 3S15E 3S1NE 3S16E 2R93E 4AYBH 5IP9E 1TWGE 2NVTE 3RZOE 3H3VF 1TWAE 4C2ME 3K7AE 4BBSE 1TWFE 3S2DE 4C3JE 3HOZE 2E2HE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2R92 E;  3GTM E;  3GTK E;  4A3K E;  1EIK A;  5M5X E;  5FJ8 E;  3HOV E;  1SFO E;  3S1M E;  5FLM E;  1I6H E;  3FKI E;  3HOW E;  4A3F E;  2E2I E;  3M4O E;  3S1Q E;  5C44 E;  5C4X E;  5IYB E;  3GTJ E;  3HOX E;  4BY1 E;  4A3I E;  3HKZ H;  3HOU E;  3HOY E;  5IYD E;  1TWC E;  5M5W E;  3H0G E;  2NVQ E;  4A3B E;  4A3E E;  2JA5 E;  3PO2 E;  4QIW H;  1Y1V E;  5M5Y E;  3GTO E;  2NVX E;  3RZD E;  4C3I E;  1DZF A;  3GTL E;  3PO3 E;  4Y7N E;  3S1R E;  4BXX E;  5C4J E;  2WB1 H;  1K83 E;  5C3E E;  1WCM E;  4A3G E;  2JA7 E;  4A3J E;  2JA6 E;  4A93 E;  2Y0S H;  3GTQ E;  5M3M E;  3I4N E;  5IYC E;  1Y1W E;  1I3Q E;  3M3Y E;  1TWH E;  4BBR E;  4C3H E;  3GTG E;  3I4M E;  2VUM E;  4A3D E;  4Y52 E;  1R9T E;  2NVY E;  2R7Z E;  2JA8 E;  3S17 E;  2YU9 E;  3S14 E;  3S2H E;  2E2J E;  2B63 E;  3GTP E;  4A3M E;  5M3F E;  4X6A E;  4A3L E;  3CQZ E;  2PMZ H;  2WAQ H;  4A3C E;  1I50 E;  4BY7 E;  5IP7 E;  3S15 E;  3S1N E;  3S16 E;  2R93 E;  4AYB H;  5IP9 E;  1TWG E;  2NVT E;  3RZO E;  3H3V F;  1TWA E;  4C2M E;  3K7A E;  4BBS E;  1TWF E;  3S2D E;  4C3J E;  3HOZ E;  2E2H E; 
#chains in the Genus database with same CATH topology
 5C4J F;  2R92 E;  4YFN E;  3GTM E;  3GTK E;  4A3K E;  1QKL A;  4XLP E;  5C3E F;  1EIK A;  1WCM F;  4MQ9 E;  3HOU F;  4KN7 E;  4LK0 E;  5M5X E;  3HOY F;  5FJ8 E;  3HOV E;  1SFO E;  2JA7 F;  3S1M E;  5IYD F;  5FLM E;  1I6H E;  5M5W F;  3H0G F;  3FKI E;  3HOW E;  5C44 F;  4A3F E;  2E2I E;  5D4E E;  4A3E F;  3M4O E;  3S1Q E;  2PMZ K;  1Y1V F;  5C44 E;  5C4X E;  5M5Y F;  3GTO F;  5IYB E;  3I4N F;  3GTJ E;  4G7Z E;  3HOX E;  4BY1 E;  4MEX E;  5IPL E;  5TMF E;  2NVX F;  3RZD F;  4XLN E;  3DXJ E;  4A3I E;  3HKZ H;  3HOU E;  4YFK E;  4LK1 E;  3WOD E;  2KRX A;  3HOY E;  5D4D E;  3PO3 F;  4C3H F;  4Y7N F;  5E18 E;  5IYD E;  2A69 E;  4OIP E;  1TWC E;  3S1R F;  2WB1 I;  2VUM F;  3GTG F;  5M5W E;  3H0G E;  1R9T F;  3I4M F;  2R7Z F;  2NVQ E;  4A3B E;  2JA8 F;  4A3E E;  2JA5 E;  3PO2 E;  4QIW H;  1Y1V E;  2YU9 F;  1K83 F;  5M5Y E;  3GTO E;  4QIW K;  2E2J F;  2O5J E;  4A3G F;  4MEY E;  4G7H E;  4ZH4 E;  1SMY E;  2A6E E;  4KN4 E;  2NVX E;  3RZD E;  1YNJ K;  2Y0S I;  4A3J F;  4A3M F;  3GTP F;  2JA6 F;  2A6H E;  4C3I E;  4A93 F;  1DZF A;  4X6A F;  3GTQ F;  3GTL E;  4YG2 E;  3PO3 E;  4LLG E;  4OIR E;  4Y7N E;  3S1R E;  4BXX E;  1I50 F;  5M3M F;  5IYC F;  5IP7 F;  5C4J E;  2WB1 H;  2R93 F;  1Y1W F;  1K83 E;  2O5I E;  5C3E E;  1I3Q F;  3M3Y F;  1WCM E;  2BE5 E;  4A3G E;  2NVT F;  1TWH F;  3H3V G;  3RZO F;  4BBR F;  1YNN K;  3HKZ K;  4BXX F;  2PPB E;  2JA7 E;  4C2M F;  3K7A F;  4OIQ E;  4BBS F;  1TWF F;  3EQL E;  4Y52 F;  4A3D F;  4YFX E;  4A3J E;  2NVY F;  5TMC E;  2JA6 E;  4A93 E;  1HQM E;  3S17 F;  5BYH E;  2Y0S H;  3GTQ E;  4C3J F;  3S14 F;  3S2H F;  4JK1 E;  2E2H F;  5M3M E;  3I4N E;  5IYC E;  5D4C E;  2B63 F;  4Q4Z E;  2CW0 E;  4XSX E;  1Y1W E;  1I3Q E;  3M3Y E;  5M3F F;  4GZY E;  3S1M F;  1TWH E;  4A3L F;  4BBR E;  3CQZ F;  1I6H F;  4C3H E;  3HOW F;  4A3C F;  3GTG E;  4KMU E;  3I4M E;  2VUM E;  4A3D E;  4Y52 E;  2A68 E;  4BY7 F;  1R9T E;  4Q5S E;  4LJZ E;  2NVY E;  2R7Z E;  2JA8 E;  3S17 E;  5IYB F;  4OIO E;  3S16 F;  3S15 F;  3S1N F;  5C4X F;  2YU9 E;  5IP9 F;  3S14 E;  3S2H E;  2E2J E;  1TWG F;  3HOX F;  4G7O E;  1TWA F;  2B63 E;  4A3I F;  3GTP E;  4A3M E;  3S2D F;  5M3F E;  4X6A E;  4A3L E;  1TWC F;  3CQZ E;  2PMZ H;  2WAQ H;  4A3C E;  3HOZ F;  2NVQ F;  4XSZ E;  2R92 F;  4A3B F;  1I50 E;  2JA5 F;  3GTM F;  4BY7 E;  5IP7 E;  2WAQ K;  4A3K F;  3GTK F;  3S15 E;  3PO2 F;  3S1N E;  3S16 E;  2R93 E;  4AYB H;  5IP9 E;  5M5X F;  3M4O F;  1TWG E;  4AYB K;  2NVT E;  5FJ8 F;  3RZO E;  1SFO F;  1IW7 E;  3H3V F;  5FLM F;  1ZYR E;  3HOV F;  1I6V E;  1TWA E;  3FKI F;  4A3F F;  2E2I F;  4C2M E;  3K7A E;  4BBS E;  4C3I F;  1TWF E;  3S1Q F;  3GTL F;  3S2D E;  4OIN E;  3GTJ F;  4C3J E;  5E17 E;  4BY1 F;  3HOZ E;  2E2H E; 
#chains in the Genus database with same CATH homology
 2R92 E;  3GTM E;  3GTK E;  4A3K E;  1EIK A;  5M5X E;  5FJ8 E;  3HOV E;  1SFO E;  3S1M E;  5FLM E;  1I6H E;  3FKI E;  3HOW E;  4A3F E;  2E2I E;  3M4O E;  3S1Q E;  5C44 E;  5C4X E;  5IYB E;  3GTJ E;  3HOX E;  4BY1 E;  4A3I E;  3HKZ H;  3HOU E;  3HOY E;  5IYD E;  1TWC E;  5M5W E;  3H0G E;  2NVQ E;  4A3B E;  4A3E E;  2JA5 E;  3PO2 E;  4QIW H;  1Y1V E;  5M5Y E;  3GTO E;  2NVX E;  3RZD E;  4C3I E;  1DZF A;  3GTL E;  3PO3 E;  4Y7N E;  3S1R E;  4BXX E;  5C4J E;  2WB1 H;  1K83 E;  5C3E E;  1WCM E;  4A3G E;  2JA7 E;  4A3J E;  2JA6 E;  4A93 E;  2Y0S H;  3GTQ E;  5M3M E;  3I4N E;  5IYC E;  1Y1W E;  1I3Q E;  3M3Y E;  1TWH E;  4BBR E;  4C3H E;  3GTG E;  3I4M E;  2VUM E;  4A3D E;  4Y52 E;  1R9T E;  2NVY E;  2R7Z E;  2JA8 E;  3S17 E;  2YU9 E;  3S14 E;  3S2H E;  2E2J E;  2B63 E;  3GTP E;  4A3M E;  5M3F E;  4X6A E;  4A3L E;  3CQZ E;  2PMZ H;  2WAQ H;  4A3C E;  1I50 E;  4BY7 E;  5IP7 E;  3S15 E;  3S1N E;  3S16 E;  2R93 E;  4AYB H;  5IP9 E;  1TWG E;  2NVT E;  3RZO E;  3H3V F;  1TWA E;  4C2M E;  3K7A E;  4BBS E;  1TWF E;  3S2D E;  4C3J E;  3HOZ E;  2E2H E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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