2JA6E

Cpd lesion containing rna polymerase ii elongation complex b
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title CPD damage recognition by transcribing RNA polymerase II.
pubmed doi rcsb
molecule tags Transferase
molecule keywords DNA-DIRECTED RNA POLYMERASE II LARGEST SUBUNIT
total genus 43
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2006-11-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 2ja6E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 2ja6E02
3GTME 5IYDE 4A3CE 3HKZH 5M3ME 3HOXE 3S14E 5M5XE 3M3YE 3S2HE 3K7AE 4C3HE 4BY1E 1DZFA 3HOYE 3HOUE 4QIWH 4A3EE 2Y0SH 3FKIE 1I50E 5M3FE 3S1QE 2R92E 4A3KE 2NVYE 5C4JE 2NVTE 5IP7E 5IYBE 2NVQE 3HOWE 5C3EE 4X6AE 2JA5E 1Y1WE 3GTLE 2E2JE 5IYCE 3HOVE 4A3ME 2WB1H 3GTPE 4BY7E 4A3FE 1Y1VE 2VUME 3H3VF 2R7ZE 3S17E 4A3DE 3S2DE 1TWGE 2JA7E 1K83E 3H0GE 1R9TE 3S1NE 5M5YE 4A3IE 3GTQE 1I3QE 2YU9E 4A3LE 3CQZE 2NVXE 1TWHE 4A3GE 4Y52E 3PO3E 3S1RE 5IP9E 2R93E 4A3JE 3PO2E 4AYBH 3GTGE 1I6HE 3S15E 5C44E 4C2ME 3S16E 3GTKE 5FLME 5C4XE 4C3IE 4Y7NE 4BBSE 3GTJE 1TWAE 2PMZH 1TWCE 4C3JE 3M4OE 5M5WE 4BBRE 2JA6E 3I4NE 4A3BE 3HOZE 3RZOE 2B63E 3I4ME 1SFOE 1WCME 2E2HE 3S1ME 4BXXE 1TWFE 5FJ8E 2WAQH 1EIKA 4A93E 3GTOE 3RZDE 2E2IE 2JA8E
chains in the Genus database with same CATH superfamily
3GTME 5IYDE 3FKIF 3S2DF 4A3CE 1I50F 5M3FF 4OIPE 3S1QF 2R92F 3HKZH 2PPBE 5M3ME 1K83F 3HOXE 4G7OE 5C4JF 2NVTF 5IP7F 3S14E 5IYBF 3GTQF 1YNNK 3CQZF 2NVQF 5M5XE 1TWHF 5C3EF 2JA5F 3HOWF 3M3YE 1Y1WF 4OIOE 5D4EE 3GTLF 3S2HE 4QIWK 2E2JF 5IYCF 4A3JF 2O5IE 4A3MF 3HOVF 3K7AE 4C3HE 4BY1E 3GTPF 4BY7F 4XLPE 5D4CE 1DZFA 3HOYE 3HOUE 4QIWH 4Q4ZE 1I6HF 4YFNE 5C44F 4C2MF 1Y1VF 5FLMF 4A3EE 2Y0SH 4MQ9E 2R7ZF 3S17F 3FKIE 4A3DF 3H3VG 1I50E 5M3FE 4LLGE 3S1QE 4OINE 2R92E 4BBSF 4A3KE 2NVYE 1TWCF 5C4JE 2NVTE 1TWGF 4Q5SE 5IP7E 4YFKE 5M5WF 2JA7F 5IYBE 3H0GF 4MEYE 4BBRF 1R9TF 4XSXE 2NVQE 3HOWE 5C3EE 4X6AE 5M5YF 2JA5E 1I3QF 4A3IF 2YU9F 2A68E 2CW0E 4A3LF 2NVXF 4A3GF 4Y52F 1Y1WE 3HOZF 3PO3F 3GTLE 2E2JE 5IYCE 3HOVE 4A3ME 2WB1H 3GTPE 5IP9F 3S1RF 4BY7E 2E2HF 2R93F 4JK1E 3PO2F 5FJ8F 4A3FE 2Y0SI 1Y1VE 3GTGF 2VUME 3H3VF 4LK0E 4XLNE 2R7ZE 3S17E 2JA8F 5D4DE 4A3DE 3S16F 3GTKF 4KMUE 3S15F 3S1NF 5C4XF 4G7ZE 3S2DE 1QKLA 4C3IF 1TWGE 5M3MF 4Y7NF 2JA7E 3GTJF 1K83E 1TWAF 4KN4E 5TMCE 3H0GE 4C3JF 4G7HE 2A6EE 3M4OF 1R9TE 3S1NE 5M5YE 4A3IE 3GTQE 1I3QE 2YU9E 4A3LE 2JA6F 4LK1E 3I4NF 3CQZE 2NVXE 1TWHE 4A3GE 4Y52E 5E17E 3PO3E 4A3BF 2WB1I 2KRXA 4ZH4E 3RZOF 4AYBK 3DXJE 3S1RE 5IP9E 2R93E 4A3JE 2B63F 2A6HE 3I4MF 2O5JE 3PO2E 1I6VE 1WCMF 1SFOF 5E18E 3S1MF 4BXXF 1TWFF 4AYBH 5BYHE 4LJZE 3GTGE 1I6HE 4A93F 3S15E 5C44E 4C2ME 3S16E 3GTKE 5FLME 5C4XE 4A3EF 3GTOF 3RZDF 2E2IF 4OIRE 2PMZK 3GTMF 5IYDF 4MEXE 4C3IE 1SMYE 4A3CF 2BE5E 3EQLE 4Y7NE 1ZYRE 4BBSE 3GTJE 1TWAE 2NVYF 2PMZH 4A3KF 1TWCE 4C3JE 3M4OE 4KN7E 3WODE 3HOXF 5M5WE 5TMFE 3S14F 4BBRE 2JA6E 3I4NE 4X6AF 5IPLE 4XSZE 4A3BE 5M5XF 3HOZE 3M3YF 3RZOE 1IW7E 2B63E 3I4ME 1YNJK 2WAQK 1HQME 4OIQE 3S2HF 1SFOE 1WCME 2E2HE 3K7AF 3S1ME 4BXXE 4BY1F 1TWFE 4C3HF 4A3FF 5FJ8E 2A69E 2WAQH 1EIKA 3HOYF 4A93E 3HOUF 2VUMF 3GTOE 4YFXE 3RZDE 2E2IE 2JA8E 4GZYE 4YG2E 3HKZK
chains in the Genus database with same CATH topology
3GTME 5IYDE 4A3CE 3HKZH 5M3ME 3HOXE 3S14E 5M5XE 3M3YE 3S2HE 3K7AE 4C3HE 4BY1E 1DZFA 3HOYE 3HOUE 4QIWH 4A3EE 2Y0SH 3FKIE 1I50E 5M3FE 3S1QE 2R92E 4A3KE 2NVYE 5C4JE 2NVTE 5IP7E 5IYBE 2NVQE 3HOWE 5C3EE 4X6AE 2JA5E 1Y1WE 3GTLE 2E2JE 5IYCE 3HOVE 4A3ME 2WB1H 3GTPE 4BY7E 4A3FE 1Y1VE 2VUME 3H3VF 2R7ZE 3S17E 4A3DE 3S2DE 1TWGE 2JA7E 1K83E 3H0GE 1R9TE 3S1NE 5M5YE 4A3IE 3GTQE 1I3QE 2YU9E 4A3LE 3CQZE 2NVXE 1TWHE 4A3GE 4Y52E 3PO3E 3S1RE 5IP9E 2R93E 4A3JE 3PO2E 4AYBH 3GTGE 1I6HE 3S15E 5C44E 4C2ME 3S16E 3GTKE 5FLME 5C4XE 4C3IE 4Y7NE 4BBSE 3GTJE 1TWAE 2PMZH 1TWCE 4C3JE 3M4OE 5M5WE 4BBRE 2JA6E 3I4NE 4A3BE 3HOZE 3RZOE 2B63E 3I4ME 1SFOE 1WCME 2E2HE 3S1ME 4BXXE 1TWFE 5FJ8E 2WAQH 1EIKA 4A93E 3GTOE 3RZDE 2E2IE 2JA8E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3GTM E;  5IYD E;  4A3C E;  3HKZ H;  5M3M E;  3HOX E;  3S14 E;  5M5X E;  3M3Y E;  3S2H E;  3K7A E;  4C3H E;  4BY1 E;  1DZF A;  3HOY E;  3HOU E;  4QIW H;  4A3E E;  2Y0S H;  3FKI E;  1I50 E;  5M3F E;  3S1Q E;  2R92 E;  4A3K E;  2NVY E;  5C4J E;  2NVT E;  5IP7 E;  5IYB E;  2NVQ E;  3HOW E;  5C3E E;  4X6A E;  2JA5 E;  1Y1W E;  3GTL E;  2E2J E;  5IYC E;  3HOV E;  4A3M E;  2WB1 H;  3GTP E;  4BY7 E;  4A3F E;  1Y1V E;  2VUM E;  3H3V F;  2R7Z E;  3S17 E;  4A3D E;  3S2D E;  1TWG E;  2JA7 E;  1K83 E;  3H0G E;  1R9T E;  3S1N E;  5M5Y E;  4A3I E;  3GTQ E;  1I3Q E;  2YU9 E;  4A3L E;  3CQZ E;  2NVX E;  1TWH E;  4A3G E;  4Y52 E;  3PO3 E;  3S1R E;  5IP9 E;  2R93 E;  4A3J E;  3PO2 E;  4AYB H;  3GTG E;  1I6H E;  3S15 E;  5C44 E;  4C2M E;  3S16 E;  3GTK E;  5FLM E;  5C4X E;  4C3I E;  4Y7N E;  4BBS E;  3GTJ E;  1TWA E;  2PMZ H;  1TWC E;  4C3J E;  3M4O E;  5M5W E;  4BBR E;  2JA6 E;  3I4N E;  4A3B E;  3HOZ E;  3RZO E;  2B63 E;  3I4M E;  1SFO E;  1WCM E;  2E2H E;  3S1M E;  4BXX E;  1TWF E;  5FJ8 E;  2WAQ H;  1EIK A;  4A93 E;  3GTO E;  3RZD E;  2E2I E;  2JA8 E; 
#chains in the Genus database with same CATH topology
 3GTM E;  5IYD E;  3FKI F;  3S2D F;  4A3C E;  1I50 F;  5M3F F;  4OIP E;  3S1Q F;  2R92 F;  3HKZ H;  2PPB E;  5M3M E;  1K83 F;  3HOX E;  4G7O E;  5C4J F;  2NVT F;  5IP7 F;  3S14 E;  5IYB F;  3GTQ F;  1YNN K;  3CQZ F;  2NVQ F;  5M5X E;  1TWH F;  5C3E F;  2JA5 F;  3HOW F;  3M3Y E;  1Y1W F;  4OIO E;  5D4E E;  3GTL F;  3S2H E;  4QIW K;  2E2J F;  5IYC F;  4A3J F;  2O5I E;  4A3M F;  3HOV F;  3K7A E;  4C3H E;  4BY1 E;  3GTP F;  4BY7 F;  4XLP E;  5D4C E;  1DZF A;  3HOY E;  3HOU E;  4QIW H;  4Q4Z E;  1I6H F;  4YFN E;  5C44 F;  4C2M F;  1Y1V F;  5FLM F;  4A3E E;  2Y0S H;  4MQ9 E;  2R7Z F;  3S17 F;  3FKI E;  4A3D F;  3H3V G;  1I50 E;  5M3F E;  4LLG E;  3S1Q E;  4OIN E;  2R92 E;  4BBS F;  4A3K E;  2NVY E;  1TWC F;  5C4J E;  2NVT E;  1TWG F;  4Q5S E;  5IP7 E;  4YFK E;  5M5W F;  2JA7 F;  5IYB E;  3H0G F;  4MEY E;  4BBR F;  1R9T F;  4XSX E;  2NVQ E;  3HOW E;  5C3E E;  4X6A E;  5M5Y F;  2JA5 E;  1I3Q F;  4A3I F;  2YU9 F;  2A68 E;  2CW0 E;  4A3L F;  2NVX F;  4A3G F;  4Y52 F;  1Y1W E;  3HOZ F;  3PO3 F;  3GTL E;  2E2J E;  5IYC E;  3HOV E;  4A3M E;  2WB1 H;  3GTP E;  5IP9 F;  3S1R F;  4BY7 E;  2E2H F;  2R93 F;  4JK1 E;  3PO2 F;  5FJ8 F;  4A3F E;  2Y0S I;  1Y1V E;  3GTG F;  2VUM E;  3H3V F;  4LK0 E;  4XLN E;  2R7Z E;  3S17 E;  2JA8 F;  5D4D E;  4A3D E;  3S16 F;  3GTK F;  4KMU E;  3S15 F;  3S1N F;  5C4X F;  4G7Z E;  3S2D E;  1QKL A;  4C3I F;  1TWG E;  5M3M F;  4Y7N F;  2JA7 E;  3GTJ F;  1K83 E;  1TWA F;  4KN4 E;  5TMC E;  3H0G E;  4C3J F;  4G7H E;  2A6E E;  3M4O F;  1R9T E;  3S1N E;  5M5Y E;  4A3I E;  3GTQ E;  1I3Q E;  2YU9 E;  4A3L E;  2JA6 F;  4LK1 E;  3I4N F;  3CQZ E;  2NVX E;  1TWH E;  4A3G E;  4Y52 E;  5E17 E;  3PO3 E;  4A3B F;  2WB1 I;  2KRX A;  4ZH4 E;  3RZO F;  4AYB K;  3DXJ E;  3S1R E;  5IP9 E;  2R93 E;  4A3J E;  2B63 F;  2A6H E;  3I4M F;  2O5J E;  3PO2 E;  1I6V E;  1WCM F;  1SFO F;  5E18 E;  3S1M F;  4BXX F;  1TWF F;  4AYB H;  5BYH E;  4LJZ E;  3GTG E;  1I6H E;  4A93 F;  3S15 E;  5C44 E;  4C2M E;  3S16 E;  3GTK E;  5FLM E;  5C4X E;  4A3E F;  3GTO F;  3RZD F;  2E2I F;  4OIR E;  2PMZ K;  3GTM F;  5IYD F;  4MEX E;  4C3I E;  1SMY E;  4A3C F;  2BE5 E;  3EQL E;  4Y7N E;  1ZYR E;  4BBS E;  3GTJ E;  1TWA E;  2NVY F;  2PMZ H;  4A3K F;  1TWC E;  4C3J E;  3M4O E;  4KN7 E;  3WOD E;  3HOX F;  5M5W E;  5TMF E;  3S14 F;  4BBR E;  2JA6 E;  3I4N E;  4X6A F;  5IPL E;  4XSZ E;  4A3B E;  5M5X F;  3HOZ E;  3M3Y F;  3RZO E;  1IW7 E;  2B63 E;  3I4M E;  1YNJ K;  2WAQ K;  1HQM E;  4OIQ E;  3S2H F;  1SFO E;  1WCM E;  2E2H E;  3K7A F;  3S1M E;  4BXX E;  4BY1 F;  1TWF E;  4C3H F;  4A3F F;  5FJ8 E;  2A69 E;  2WAQ H;  1EIK A;  3HOY F;  4A93 E;  3HOU F;  2VUM F;  3GTO E;  4YFX E;  3RZD E;  2E2I E;  2JA8 E;  4GZY E;  4YG2 E;  3HKZ K; 
#chains in the Genus database with same CATH homology
 3GTM E;  5IYD E;  4A3C E;  3HKZ H;  5M3M E;  3HOX E;  3S14 E;  5M5X E;  3M3Y E;  3S2H E;  3K7A E;  4C3H E;  4BY1 E;  1DZF A;  3HOY E;  3HOU E;  4QIW H;  4A3E E;  2Y0S H;  3FKI E;  1I50 E;  5M3F E;  3S1Q E;  2R92 E;  4A3K E;  2NVY E;  5C4J E;  2NVT E;  5IP7 E;  5IYB E;  2NVQ E;  3HOW E;  5C3E E;  4X6A E;  2JA5 E;  1Y1W E;  3GTL E;  2E2J E;  5IYC E;  3HOV E;  4A3M E;  2WB1 H;  3GTP E;  4BY7 E;  4A3F E;  1Y1V E;  2VUM E;  3H3V F;  2R7Z E;  3S17 E;  4A3D E;  3S2D E;  1TWG E;  2JA7 E;  1K83 E;  3H0G E;  1R9T E;  3S1N E;  5M5Y E;  4A3I E;  3GTQ E;  1I3Q E;  2YU9 E;  4A3L E;  3CQZ E;  2NVX E;  1TWH E;  4A3G E;  4Y52 E;  3PO3 E;  3S1R E;  5IP9 E;  2R93 E;  4A3J E;  3PO2 E;  4AYB H;  3GTG E;  1I6H E;  3S15 E;  5C44 E;  4C2M E;  3S16 E;  3GTK E;  5FLM E;  5C4X E;  4C3I E;  4Y7N E;  4BBS E;  3GTJ E;  1TWA E;  2PMZ H;  1TWC E;  4C3J E;  3M4O E;  5M5W E;  4BBR E;  2JA6 E;  3I4N E;  4A3B E;  3HOZ E;  3RZO E;  2B63 E;  3I4M E;  1SFO E;  1WCM E;  2E2H E;  3S1M E;  4BXX E;  1TWF E;  5FJ8 E;  2WAQ H;  1EIK A;  4A93 E;  3GTO E;  3RZD E;  2E2I E;  2JA8 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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