2KAII

Refined 2.5 angstroms x-ray crystal structure of the complex formed by porcine kallikrein a and the bovine pancreatic trypsin inhibitor. crystallization, patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin-pancreatic trypsin inhibitor complex
Total Genus 6
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
6
sequence length
56
structure length
56
Chain Sequence
PDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its components and with the bovine trypsin-pancreatic trypsin inhibitor complex
pubmed doi rcsb
molecule tags Complex (proteinase-inhibitor)
source organism Sus scrofa
molecule keywords KALLIKREIN A
total genus 6
structure length 56
sequence length 56
ec nomenclature
pdb deposition date 1984-05-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2kaiI00
1OA55 1ADZA 1AAPA 2FI5I 3TGKI 4DG4C 3WNYA 1DEMA 1TOCR 2ZJXA 1BIKA 1JV9A 1EAWB 1LD6A 1T8NB 2J6DA 2RA3C 3D65I 3BTGI 5JB4A 1T8OB 1F7ZI 3BTMI 4Y0ZI 1LD5A 1MTND 4Y0YI 1YLDB 4Y10I 9PTIA 3BTFI 4U30W 1BF0A 1CA0D 2LFKA 1BHCA 2HEXA 4BNRI 1Y62A 4ISLB 1EJMB 2KNTA 2R9PE 1YLCB 3AUHA 5PTIA 2UUYB 1BPIA 1D0DB 1CO7I 5C67C 1T8LB 3AUIA 2ZVXA 4BD9B 1KTHA 3BTEI 2FI3I 1NAGA 2UUXA 2KCRA 4NTWB 3LDMA 1KNTA 3UOUB 1P2JI 8PTIA 1FAKI 6PTIA 3BTDI 5JB6A 3BTTI 1P2MB 2JOTA 2DDJA 3BYBA 3GYMI 4NTYB 1BZXI 1QLQA 3TGJI 1BUNB 1OA65 4DTGK 3BTQI 1SHPA 5JB5A 1T8MB 4NTXB 1BTIA 1KUNA 1P2KI 1TFXC 3FP8I 1YKTB 2M99A 1TAWB 2TGPI 1TPAI 1BRBI 1BPTA 2LFLA 2PTCI 4BQDA 7PTIA 1P2OB 3BTHI 1BRCI 3LDIA 1F5RI 1TCPA 4ISOB 3AUEA 4U32X 4TPII 2TPII 1G6XA 2FTMB 1TAPA 3T62D 1JC6A 1ZR0B 4WXVC 2DDIA 3AUBA 4PTIA 1JV8A 3BTKI 1IRHA 1BTHP 1T7CB 3TGII 3LDJA 1YC0I 5JB7A 1P2NB 3TPII 1CBWD 1UUAA 2W8XA 3AUCA 1D0DA 1BZ5A 2FI4I 1FY8I 2KAII 2ODYE 4ISNB 4WWYC 1DENA 4Y11I 3U1JE 1KIGI 3P95E 3UIRC 3M7QB 3FP6I 2CA7A 1DTXA 2FTLI 1PITA 3FP7J 1ZJDB 3OTJI 3P92E 3OFWA 3BTWI 1P2II 3CI7A 1UUBA 3L3TE 2IJOI 3AUDA 1P2QB 3L33E 1DTKA 1B0CA 1FANA 1AALA 3AUGA 2M01A 1K6UA
chains in the Genus database with same CATH superfamily
1OA55 1ADZA 1AAPA 2FI5I 3TGKI 4DG4C 3WNYA 1DEMA 1TOCR 2ZJXA 1BIKA 1JV9A 1EAWB 1LD6A 1T8NB 2J6DA 2RA3C 3D65I 3BTGI 5JB4A 1T8OB 1F7ZI 3BTMI 4Y0ZI 1LD5A 1MTND 4Y0YI 1YLDB 4Y10I 9PTIA 3BTFI 4U30W 1BF0A 1CA0D 2LFKA 1BHCA 2HEXA 4BNRI 1Y62A 4ISLB 1EJMB 2KNTA 2R9PE 1YLCB 3AUHA 5PTIA 2UUYB 1BPIA 1D0DB 1CO7I 5C67C 1T8LB 3AUIA 2ZVXA 4BD9B 1KTHA 3BTEI 2FI3I 1NAGA 2UUXA 2KCRA 4NTWB 3LDMA 1KNTA 3UOUB 1P2JI 8PTIA 1FAKI 6PTIA 3BTDI 5JB6A 3BTTI 1P2MB 2JOTA 2DDJA 3BYBA 3GYMI 4NTYB 1BZXI 1QLQA 3TGJI 1BUNB 1OA65 4DTGK 3BTQI 1SHPA 5JB5A 1T8MB 4NTXB 1BTIA 1KUNA 1P2KI 1TFXC 3FP8I 1YKTB 2M99A 1TAWB 2TGPI 1TPAI 1BRBI 1BPTA 2LFLA 2PTCI 4BQDA 7PTIA 1P2OB 3BTHI 1BRCI 3LDIA 1F5RI 1TCPA 4ISOB 3AUEA 4U32X 4TPII 2TPII 1G6XA 2FTMB 1TAPA 3T62D 1JC6A 1ZR0B 4WXVC 2DDIA 3AUBA 4PTIA 1JV8A 3BTKI 1IRHA 1BTHP 1T7CB 3TGII 3LDJA 1YC0I 5JB7A 1P2NB 3TPII 1CBWD 1UUAA 2W8XA 3AUCA 1D0DA 1BZ5A 2FI4I 1FY8I 2KAII 2ODYE 4ISNB 4WWYC 1DENA 4Y11I 3U1JE 1KIGI 3P95E 3UIRC 3M7QB 3FP6I 2CA7A 1DTXA 2FTLI 1PITA 3FP7J 1ZJDB 3OTJI 3P92E 3OFWA 3BTWI 1P2II 3CI7A 1UUBA 3L3TE 2IJOI 3AUDA 1P2QB 3L33E 1DTKA 1B0CA 1FANA 1AALA 3AUGA 2M01A 1K6UA
chains in the Genus database with same CATH topology
1OA55 1ADZA 1AAPA 2FI5I 3TGKI 4DG4C 3WNYA 1DEMA 1TOCR 2ZJXA 1BIKA 1JV9A 1EAWB 1LD6A 1T8NB 2J6DA 2RA3C 3D65I 3BTGI 5JB4A 1T8OB 1F7ZI 3BTMI 4Y0ZI 1LD5A 1MTND 4Y0YI 1YLDB 4Y10I 9PTIA 3BTFI 4U30W 1BF0A 1CA0D 2LFKA 1BHCA 2HEXA 4BNRI 1Y62A 4ISLB 1EJMB 2KNTA 2R9PE 1YLCB 3AUHA 5PTIA 2UUYB 1BPIA 1D0DB 1CO7I 5C67C 1T8LB 3AUIA 2ZVXA 4BD9B 1KTHA 3BTEI 2FI3I 1NAGA 2UUXA 2KCRA 4NTWB 3LDMA 1KNTA 3UOUB 1P2JI 8PTIA 1FAKI 6PTIA 3BTDI 5JB6A 3BTTI 1P2MB 2JOTA 2DDJA 3BYBA 3GYMI 4NTYB 1BZXI 1QLQA 3TGJI 1BUNB 1OA65 4DTGK 3BTQI 1SHPA 5JB5A 1T8MB 4NTXB 1BTIA 1KUNA 1P2KI 1TFXC 3FP8I 1YKTB 2M99A 1TAWB 2TGPI 1TPAI 1BRBI 1BPTA 2LFLA 2PTCI 4BQDA 7PTIA 1P2OB 3BTHI 1BRCI 3LDIA 1F5RI 1TCPA 4ISOB 3AUEA 4U32X 4TPII 2TPII 1G6XA 2FTMB 1TAPA 3T62D 1JC6A 1ZR0B 4WXVC 2DDIA 3AUBA 4PTIA 1JV8A 3BTKI 1IRHA 1BTHP 1T7CB 3TGII 3LDJA 1YC0I 5JB7A 1P2NB 3TPII 1CBWD 1UUAA 2W8XA 3AUCA 1D0DA 1BZ5A 2FI4I 1FY8I 2KAII 2ODYE 4ISNB 4WWYC 1DENA 4Y11I 3U1JE 1KIGI 3P95E 3UIRC 3M7QB 3FP6I 2CA7A 1DTXA 2FTLI 1PITA 3FP7J 1ZJDB 3OTJI 3P92E 3OFWA 3BTWI 1P2II 3CI7A 1UUBA 3L3TE 2IJOI 3AUDA 1P2QB 3L33E 1DTKA 1B0CA 1FANA 1AALA 3AUGA 2M01A 1K6UA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OA5 5;  1ADZ A;  1AAP A;  2FI5 I;  3TGK I;  4DG4 C;  3WNY A;  1DEM A;  1TOC R;  2ZJX A;  1BIK A;  1JV9 A;  1EAW B;  1LD6 A;  1T8N B;  2J6D A;  2RA3 C;  3D65 I;  3BTG I;  5JB4 A;  1T8O B;  1F7Z I;  3BTM I;  4Y0Z I;  1LD5 A;  1MTN D;  4Y0Y I;  1YLD B;  4Y10 I;  9PTI A;  3BTF I;  4U30 W;  1BF0 A;  1CA0 D;  2LFK A;  1BHC A;  2HEX A;  4BNR I;  1Y62 A;  4ISL B;  1EJM B;  2KNT A;  2R9P E;  1YLC B;  3AUH A;  5PTI A;  2UUY B;  1BPI A;  1D0D B;  1CO7 I;  5C67 C;  1T8L B;  3AUI A;  2ZVX A;  4BD9 B;  1KTH A;  3BTE I;  2FI3 I;  1NAG A;  2UUX A;  2KCR A;  4NTW B;  3LDM A;  1KNT A;  3UOU B;  1P2J I;  8PTI A;  1FAK I;  6PTI A;  3BTD I;  5JB6 A;  3BTT I;  1P2M B;  2JOT A;  2DDJ A;  3BYB A;  3GYM I;  4NTY B;  1BZX I;  1QLQ A;  3TGJ I;  1BUN B;  1OA6 5;  4DTG K;  3BTQ I;  1SHP A;  5JB5 A;  1T8M B;  4NTX B;  1BTI A;  1KUN A;  1P2K I;  1TFX C;  3FP8 I;  1YKT B;  2M99 A;  1TAW B;  2TGP I;  1TPA I;  1BRB I;  1BPT A;  2LFL A;  2PTC I;  4BQD A;  7PTI A;  1P2O B;  3BTH I;  1BRC I;  3LDI A;  1F5R I;  1TCP A;  4ISO B;  3AUE A;  4U32 X;  4TPI I;  2TPI I;  1G6X A;  2FTM B;  1TAP A;  3T62 D;  1JC6 A;  1ZR0 B;  4WXV C;  2DDI A;  3AUB A;  4PTI A;  1JV8 A;  3BTK I;  1IRH A;  1BTH P;  1T7C B;  3TGI I;  3LDJ A;  1YC0 I;  5JB7 A;  1P2N B;  3TPI I;  1CBW D;  1UUA A;  2W8X A;  3AUC A;  1D0D A;  1BZ5 A;  2FI4 I;  1FY8 I;  2KAI I;  2ODY E;  4ISN B;  4WWY C;  1DEN A;  4Y11 I;  3U1J E;  1KIG I;  3P95 E;  3UIR C;  3M7Q B;  3FP6 I;  2CA7 A;  1DTX A;  2FTL I;  1PIT A;  3FP7 J;  1ZJD B;  3OTJ I;  3P92 E;  3OFW A;  3BTW I;  1P2I I;  3CI7 A;  1UUB A;  3L3T E;  2IJO I;  3AUD A;  1P2Q B;  3L33 E;  1DTK A;  1B0C A;  1FAN A;  1AAL A;  3AUG A;  2M01 A;  1K6U A; 
#chains in the Genus database with same CATH topology
 1OA5 5;  1ADZ A;  1AAP A;  2FI5 I;  3TGK I;  4DG4 C;  3WNY A;  1DEM A;  1TOC R;  2ZJX A;  1BIK A;  1JV9 A;  1EAW B;  1LD6 A;  1T8N B;  2J6D A;  2RA3 C;  3D65 I;  3BTG I;  5JB4 A;  1T8O B;  1F7Z I;  3BTM I;  4Y0Z I;  1LD5 A;  1MTN D;  4Y0Y I;  1YLD B;  4Y10 I;  9PTI A;  3BTF I;  4U30 W;  1BF0 A;  1CA0 D;  2LFK A;  1BHC A;  2HEX A;  4BNR I;  1Y62 A;  4ISL B;  1EJM B;  2KNT A;  2R9P E;  1YLC B;  3AUH A;  5PTI A;  2UUY B;  1BPI A;  1D0D B;  1CO7 I;  5C67 C;  1T8L B;  3AUI A;  2ZVX A;  4BD9 B;  1KTH A;  3BTE I;  2FI3 I;  1NAG A;  2UUX A;  2KCR A;  4NTW B;  3LDM A;  1KNT A;  3UOU B;  1P2J I;  8PTI A;  1FAK I;  6PTI A;  3BTD I;  5JB6 A;  3BTT I;  1P2M B;  2JOT A;  2DDJ A;  3BYB A;  3GYM I;  4NTY B;  1BZX I;  1QLQ A;  3TGJ I;  1BUN B;  1OA6 5;  4DTG K;  3BTQ I;  1SHP A;  5JB5 A;  1T8M B;  4NTX B;  1BTI A;  1KUN A;  1P2K I;  1TFX C;  3FP8 I;  1YKT B;  2M99 A;  1TAW B;  2TGP I;  1TPA I;  1BRB I;  1BPT A;  2LFL A;  2PTC I;  4BQD A;  7PTI A;  1P2O B;  3BTH I;  1BRC I;  3LDI A;  1F5R I;  1TCP A;  4ISO B;  3AUE A;  4U32 X;  4TPI I;  2TPI I;  1G6X A;  2FTM B;  1TAP A;  3T62 D;  1JC6 A;  1ZR0 B;  4WXV C;  2DDI A;  3AUB A;  4PTI A;  1JV8 A;  3BTK I;  1IRH A;  1BTH P;  1T7C B;  3TGI I;  3LDJ A;  1YC0 I;  5JB7 A;  1P2N B;  3TPI I;  1CBW D;  1UUA A;  2W8X A;  3AUC A;  1D0D A;  1BZ5 A;  2FI4 I;  1FY8 I;  2KAI I;  2ODY E;  4ISN B;  4WWY C;  1DEN A;  4Y11 I;  3U1J E;  1KIG I;  3P95 E;  3UIR C;  3M7Q B;  3FP6 I;  2CA7 A;  1DTX A;  2FTL I;  1PIT A;  3FP7 J;  1ZJD B;  3OTJ I;  3P92 E;  3OFW A;  3BTW I;  1P2I I;  3CI7 A;  1UUB A;  3L3T E;  2IJO I;  3AUD A;  1P2Q B;  3L33 E;  1DTK A;  1B0C A;  1FAN A;  1AAL A;  3AUG A;  2M01 A;  1K6U A; 
#chains in the Genus database with same CATH homology
 1OA5 5;  1ADZ A;  1AAP A;  2FI5 I;  3TGK I;  4DG4 C;  3WNY A;  1DEM A;  1TOC R;  2ZJX A;  1BIK A;  1JV9 A;  1EAW B;  1LD6 A;  1T8N B;  2J6D A;  2RA3 C;  3D65 I;  3BTG I;  5JB4 A;  1T8O B;  1F7Z I;  3BTM I;  4Y0Z I;  1LD5 A;  1MTN D;  4Y0Y I;  1YLD B;  4Y10 I;  9PTI A;  3BTF I;  4U30 W;  1BF0 A;  1CA0 D;  2LFK A;  1BHC A;  2HEX A;  4BNR I;  1Y62 A;  4ISL B;  1EJM B;  2KNT A;  2R9P E;  1YLC B;  3AUH A;  5PTI A;  2UUY B;  1BPI A;  1D0D B;  1CO7 I;  5C67 C;  1T8L B;  3AUI A;  2ZVX A;  4BD9 B;  1KTH A;  3BTE I;  2FI3 I;  1NAG A;  2UUX A;  2KCR A;  4NTW B;  3LDM A;  1KNT A;  3UOU B;  1P2J I;  8PTI A;  1FAK I;  6PTI A;  3BTD I;  5JB6 A;  3BTT I;  1P2M B;  2JOT A;  2DDJ A;  3BYB A;  3GYM I;  4NTY B;  1BZX I;  1QLQ A;  3TGJ I;  1BUN B;  1OA6 5;  4DTG K;  3BTQ I;  1SHP A;  5JB5 A;  1T8M B;  4NTX B;  1BTI A;  1KUN A;  1P2K I;  1TFX C;  3FP8 I;  1YKT B;  2M99 A;  1TAW B;  2TGP I;  1TPA I;  1BRB I;  1BPT A;  2LFL A;  2PTC I;  4BQD A;  7PTI A;  1P2O B;  3BTH I;  1BRC I;  3LDI A;  1F5R I;  1TCP A;  4ISO B;  3AUE A;  4U32 X;  4TPI I;  2TPI I;  1G6X A;  2FTM B;  1TAP A;  3T62 D;  1JC6 A;  1ZR0 B;  4WXV C;  2DDI A;  3AUB A;  4PTI A;  1JV8 A;  3BTK I;  1IRH A;  1BTH P;  1T7C B;  3TGI I;  3LDJ A;  1YC0 I;  5JB7 A;  1P2N B;  3TPI I;  1CBW D;  1UUA A;  2W8X A;  3AUC A;  1D0D A;  1BZ5 A;  2FI4 I;  1FY8 I;  2KAI I;  2ODY E;  4ISN B;  4WWY C;  1DEN A;  4Y11 I;  3U1J E;  1KIG I;  3P95 E;  3UIR C;  3M7Q B;  3FP6 I;  2CA7 A;  1DTX A;  2FTL I;  1PIT A;  3FP7 J;  1ZJD B;  3OTJ I;  3P92 E;  3OFW A;  3BTW I;  1P2I I;  3CI7 A;  1UUB A;  3L3T E;  2IJO I;  3AUD A;  1P2Q B;  3L33 E;  1DTK A;  1B0C A;  1FAN A;  1AAL A;  3AUG A;  2M01 A;  1K6U A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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