2MQSA

Transient collagen triple helix binding to a key metalloproteinase in invasion and development: spin labels to structure
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
196
structure length
196
Chain Sequence
PNICDGNFDTVAMLRGEMFVFKERWFWRVRNNQVMDGYPMPIGQFWRGLPASINTAYERKDGKFVFFKGDKHWVFDEASLEPGYPKHIKELGRGLPTDKIDAALFWMPNGKTYFFRGNKYYRFNEELRAVDSEYPKNIKVWEGIPESPRGSFMGSDEVFTYFYKGNKYWKFNNQKLKVEPGYPKSALRDWMGCPSG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Matrix metalloproteinase-14
publication title Transient collagen triple helix binding to a key metalloproteinase in invasion and development.
pubmed doi rcsb
source organism Homo sapiens
total genus 47
structure length 196
sequence length 196
ec nomenclature ec 3.4.24.80: Membrane-type matrix metalloproteinase-1.
pdb deposition date 2014-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00045 Hemopexin Hemopexin
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.110.10.10 Mainly Beta 4 Propeller Hemopexin Hemopexin-like domain 2mqsA00
1HXNA 1SU3A 3V6NA 2MQSA 1QHUA 4YEHA 1ITVA 4FU4A 4G0DA 1GXDA 2CLTA 3C7XA 1GENA 4HSDA 3S18A 4OEIA 3OYOA 4AUOA 4RT6B 1QJSA 4LL2A 1RTGA 4FVLA 1CK7A 3BA0A 2JXYA 3LP9A 1FBLA 1PEXA
chains in the Genus database with same CATH superfamily
1HXNA 1SU3A 3V6NA 2MQSA 1QHUA 4YEHA 1ITVA 4FU4A 4G0DA 1GXDA 2CLTA 3C7XA 1GENA 4HSDA 3S18A 4OEIA 3OYOA 4AUOA 4RT6B 1QJSA 4LL2A 1RTGA 4FVLA 1CK7A 3BA0A 2JXYA 3LP9A 1FBLA 1PEXA
chains in the Genus database with same CATH topology
1HXNA 1SU3A 3V6NA 2MQSA 1QHUA 4YEHA 1ITVA 4FU4A 4G0DA 1GXDA 2CLTA 3C7XA 1GENA 4HSDA 3S18A 4OEIA 3OYOA 4AUOA 4RT6B 1QJSA 4LL2A 1RTGA 4FVLA 1CK7A 3BA0A 2JXYA 3LP9A 1FBLA 1PEXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1HXN A;  1SU3 A;  3V6N A;  2MQS A;  1QHU A;  4YEH A;  1ITV A;  4FU4 A;  4G0D A;  1GXD A;  2CLT A;  3C7X A;  1GEN A;  4HSD A;  3S18 A;  4OEI A;  3OYO A;  4AUO A;  4RT6 B;  1QJS A;  4LL2 A;  1RTG A;  4FVL A;  1CK7 A;  3BA0 A;  2JXY A;  3LP9 A;  1FBL A;  1PEX A; 
#chains in the Genus database with same CATH topology
 1HXN A;  1SU3 A;  3V6N A;  2MQS A;  1QHU A;  4YEH A;  1ITV A;  4FU4 A;  4G0D A;  1GXD A;  2CLT A;  3C7X A;  1GEN A;  4HSD A;  3S18 A;  4OEI A;  3OYO A;  4AUO A;  4RT6 B;  1QJS A;  4LL2 A;  1RTG A;  4FVL A;  1CK7 A;  3BA0 A;  2JXY A;  3LP9 A;  1FBL A;  1PEX A; 
#chains in the Genus database with same CATH homology
 1HXN A;  1SU3 A;  3V6N A;  2MQS A;  1QHU A;  4YEH A;  1ITV A;  4FU4 A;  4G0D A;  1GXD A;  2CLT A;  3C7X A;  1GEN A;  4HSD A;  3S18 A;  4OEI A;  3OYO A;  4AUO A;  4RT6 B;  1QJS A;  4LL2 A;  1RTG A;  4FVL A;  1CK7 A;  3BA0 A;  2JXY A;  3LP9 A;  1FBL A;  1PEX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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