2NVXF

Rna polymerase ii elongation complex in 5 mm mg+2 with 2'-dutp
Total Genus 17
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
17
sequence length
88
structure length
88
Chain Sequence
TLKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 17
structure length 88
sequence length 88
ec nomenclature
pdb deposition date 2006-11-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 2nvxF00
3HOVF 4OIPE 4Y52F 3FKIF 4G7OE 3HKZK 5E17E 4C3HF 4GZYE 4YFNE 2PMZK 4XLNE 3HOWF 5IYCF 2NVQF 4A3JF 1Y1WF 1SMYE 5M5YF 4A3FF 4BY7F 2A69E 4Q5SE 5C3EF 4OINE 5D4CE 4A3DF 5IYDF 3S1RF 4C3IF 2NVTF 3HOZF 3I4NF 5IP9F 4A3CF 3H0GF 1HQME 2A6HE 1QKLA 5TMCE 4ZH4E 2WAQK 4A3GF 4XSZE 3HOXF 3I4MF 2Y0SI 4Q4ZE 1TWAF 1K83F 1I6HF 4MQ9E 3GTMF 1R9TF 4A3IF 4AYBK 3K7AF 4KMUE 5FLMF 3GTJF 2O5IE 2R7ZF 3M4OF 5FJ8F 5E18E 4A3MF 4A3KF 4MEYE 4C3JF 5C4XF 2O5JE 5D4EE 4C2MF 2B63F 4OIRE 4G7HE 3PO3F 3GTOF 4YG2E 3GTPF 3M3YF 4LK0E 4OIOE 3PO2F 3HOUF 1TWGF 3GTGF 3S14F 4A93F 5BYHE 4G7ZE 5M5XF 4X6AF 3S2HF 2A6EE 3S1MF 2E2JF 2PPBE 4A3EF 2YU9F 1IW7E 4LK1E 2CW0E 3EQLE 4YFKE 3DXJE 5M3MF 4KN7E 3S2DF 3S1NF 2E2HF 5M5WF 4A3BF 4KN4E 4LJZE 5IP7F 2JA8F 3H3VG 3WODE 2NVXF 4XLPE 4OIQE 1TWCF 4XSXE 5TMFE 4A3LF 3S16F 3S1QF 2JA5F 1ZYRE 2R93F 3S15F 3GTLF 1WCMF 3CQZF 2VUMF 3GTKF 1I6VE 3HOYF 1I3QF 3RZDF 5C4JF 2JA6F 1Y1VF 4BBRF 2NVYF 5C44F 4Y7NF 1YNJK 2A68E 1TWHF 2JA7F 5IPLE 5IYBF 5D4DE 4MEXE 2BE5E 2WB1I 3GTQF 2E2IF 3RZOF 1TWFF 4BXXF 4BY1F 3S17F 1YNNK 1I50F 4JK1E 2R92F 1SFOF 4YFXE 4BBSF 4LLGE 5M3FF
chains in the Genus database with same CATH superfamily
3HOVF 4OIPE 4Y52F 3M3YE 3FKIF 4G7OE 1TWGE 3HKZK 3GTGE 3S14E 5E17E 4C3HF 4A93E 3S16E 4X6AE 4GZYE 4YFNE 2PMZK 3S2HE 4XLNE 1I3QE 5IYCF 2JA6E 4A3JF 1Y1WF 2NVQF 1SMYE 5M5YF 3HOWF 3S1ME 2E2JE 1Y1VE 4A3FF 4A3EE 4BY7F 2A69E 5C44E 2YU9E 4Q5SE 1TWHE 5C3EF 4OINE 5IYBE 5D4CE 4A3DF 5IYDF 3S1RF 4C3IF 2NVTF 4QIWH 1TWFE 5M3ME 3HOZF 3RZOE 3I4NF 4BY1E 3S2DE 2E2HE 4BXXE 3S1NE 5IP9F 4QIWK 4A3BE 4A3CF 3H0GF 5IP7E 2NVXE 1HQME 4BBSE 1TWCE 2A6HE 3HOVE 1QKLA 3S1QE 5TMCE 2WB1H 4ZH4E 2WAQK 4A3GF 4XSZE 3HKZH 3HOXF 2JA5E 3I4MF 2Y0SI 4Q4ZE 1TWAF 1K83F 1I6HF 4MQ9E 3S15E 2R93E 3GTLE 1WCME 2PMZH 3CQZE 2VUME 3GTMF 1DZFA 3GTKE 3HOYE 1R9TF 4A3IF 4AYBK 3K7AF 4KMUE 5IYCE 3HOWE 3RZDE 5FLMF 5C4JE 3GTJF 2O5IE 2R7ZF 3M4OF 3H3VF 4BBRE 5FJ8F 5E18E 2NVYE 4A3MF 4Y7NE 4A3KF 4MEYE 4C3JF 2JA7E 2O5JE 5D4EE 5C4XF 4C2MF 3GTQE 2B63F 2E2IE 4OIRE 4G7HE 5IP9E 3PO3F 3S17E 3GTOF 1I50E 4YG2E 2R92E 1SFOE 3GTPF 3M3YF 4LK0E 4OIOE 3PO2F 2WAQH 5M3FE 1Y1WE 3HOUF 1TWGF 3GTGF 3S14F 4Y52E 4A93F 3I4ME 3FKIE 5BYHE 4G7ZE 5M5XF 4X6AF 3S2HF 4C3HE 2A6EE 4AYBH 3S1MF 2E2JF 2PPBE 4A3EF 2NVQE 4A3JE 5M5YE 2YU9F 4A3FE 2Y0SH 1IW7E 4A3ME 4LK1E 4BY7E 2CW0E 5C4XE 3EQLE 4YFKE 3DXJE 5M3MF 5C3EE 4KN7E 3S2DF 3S1NF 2E2HF 4A3DE 5M5WF 4A3BF 5IYDE 3S1RE 4C3IE 2NVTE 4KN4E 4LJZE 5IP7F 3HOZE 2JA8F 3I4NE 3H3VG 3WODE 2NVXF 3PO3E 4XLPE 4OIQE 1TWCF 4XSXE 5TMFE 4A3LF 4A3CE 3H0GE 3S16F 3S1QF 3GTPE 3PO2E 2JA5F 1ZYRE 3HOUE 2R93F 3S15F 4A3GE 3GTLF 1WCMF 3HOXE 3CQZF 5M5XE 2VUMF 3GTKF 1K83E 1I6VE 1TWAE 3HOYF 1I6HE 1I3QF 3RZDF 5C4JF 2JA6F 3GTME 1R9TE 4A3IE 1Y1VF 3K7AE 4BBRF 5FLME 2NVYF 5C44F 3GTJE 4Y7NF 1YNJK 2A68E 1TWHF 2JA7F 2R7ZE 5IYBF 5D4DE 4MEXE 3M4OE 5FJ8E 5IPLE 1EIKA 2BE5E 2WB1I 4A3KE 3GTQF 4C3JE 2E2IF 3RZOF 1TWFF 4BXXF 5M5WE 4BY1F 2KRXA 4C2ME 3S17F 2B63E 2JA8E 1YNNK 1I50F 4JK1E 2R92F 1SFOF 4YFXE 4A3LE 4BBSF 4LLGE 5M3FF 3GTOE
chains in the Genus database with same CATH topology
3HOVF 4OIPE 4Y52F 3FKIF 4G7OE 3HKZK 5E17E 4C3HF 4GZYE 4YFNE 2PMZK 4XLNE 3HOWF 5IYCF 2NVQF 4A3JF 1Y1WF 1SMYE 5M5YF 4A3FF 4BY7F 2A69E 4Q5SE 5C3EF 4OINE 5D4CE 4A3DF 5IYDF 3S1RF 4C3IF 2NVTF 3HOZF 3I4NF 5IP9F 4QIWK 4A3CF 3H0GF 1HQME 2A6HE 1QKLA 5TMCE 4ZH4E 2WAQK 4A3GF 4XSZE 3HOXF 3I4MF 2Y0SI 4Q4ZE 1TWAF 1K83F 1I6HF 4MQ9E 3GTMF 1R9TF 4A3IF 4AYBK 3K7AF 4KMUE 5FLMF 3GTJF 2O5IE 2R7ZF 3M4OF 5FJ8F 5E18E 4A3MF 4A3KF 4MEYE 4C3JF 5C4XF 2O5JE 5D4EE 4C2MF 2B63F 4OIRE 4G7HE 3PO3F 3GTOF 4YG2E 3GTPF 3M3YF 4LK0E 4OIOE 3PO2F 3HOUF 1TWGF 3GTGF 3S14F 4A93F 5BYHE 4G7ZE 5M5XF 4X6AF 3S2HF 2A6EE 3S1MF 2E2JF 2PPBE 4A3EF 2YU9F 1IW7E 4LK1E 2CW0E 3EQLE 4YFKE 3DXJE 5M3MF 4KN7E 3S2DF 3S1NF 2E2HF 5M5WF 4A3BF 4KN4E 4LJZE 5IP7F 2JA8F 3H3VG 3WODE 2NVXF 4XLPE 4OIQE 1TWCF 4XSXE 5TMFE 4A3LF 3S16F 3S1QF 2JA5F 1ZYRE 2R93F 3S15F 3GTLF 1WCMF 3CQZF 2VUMF 3GTKF 1I6VE 3HOYF 1I3QF 3RZDF 5C4JF 2JA6F 1Y1VF 4BBRF 2NVYF 5C44F 4Y7NF 1YNJK 2A68E 1TWHF 2JA7F 5IPLE 5IYBF 5D4DE 4MEXE 2BE5E 2WB1I 3GTQF 2E2IF 3RZOF 1TWFF 4BXXF 4BY1F 2KRXA 3S17F 1YNNK 1I50F 4JK1E 2R92F 1SFOF 4YFXE 4BBSF 4LLGE 5M3FF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOV F;  4OIP E;  4Y52 F;  3FKI F;  4G7O E;  3HKZ K;  5E17 E;  4C3H F;  4GZY E;  4YFN E;  2PMZ K;  4XLN E;  3HOW F;  5IYC F;  2NVQ F;  4A3J F;  1Y1W F;  1SMY E;  5M5Y F;  4A3F F;  4BY7 F;  2A69 E;  4Q5S E;  5C3E F;  4OIN E;  5D4C E;  4A3D F;  5IYD F;  3S1R F;  4C3I F;  2NVT F;  3HOZ F;  3I4N F;  5IP9 F;  4A3C F;  3H0G F;  1HQM E;  2A6H E;  1QKL A;  5TMC E;  4ZH4 E;  2WAQ K;  4A3G F;  4XSZ E;  3HOX F;  3I4M F;  2Y0S I;  4Q4Z E;  1TWA F;  1K83 F;  1I6H F;  4MQ9 E;  3GTM F;  1R9T F;  4A3I F;  4AYB K;  3K7A F;  4KMU E;  5FLM F;  3GTJ F;  2O5I E;  2R7Z F;  3M4O F;  5FJ8 F;  5E18 E;  4A3M F;  4A3K F;  4MEY E;  4C3J F;  5C4X F;  2O5J E;  5D4E E;  4C2M F;  2B63 F;  4OIR E;  4G7H E;  3PO3 F;  3GTO F;  4YG2 E;  3GTP F;  3M3Y F;  4LK0 E;  4OIO E;  3PO2 F;  3HOU F;  1TWG F;  3GTG F;  3S14 F;  4A93 F;  5BYH E;  4G7Z E;  5M5X F;  4X6A F;  3S2H F;  2A6E E;  3S1M F;  2E2J F;  2PPB E;  4A3E F;  2YU9 F;  1IW7 E;  4LK1 E;  2CW0 E;  3EQL E;  4YFK E;  3DXJ E;  5M3M F;  4KN7 E;  3S2D F;  3S1N F;  2E2H F;  5M5W F;  4A3B F;  4KN4 E;  4LJZ E;  5IP7 F;  2JA8 F;  3H3V G;  3WOD E;  2NVX F;  4XLP E;  4OIQ E;  1TWC F;  4XSX E;  5TMF E;  4A3L F;  3S16 F;  3S1Q F;  2JA5 F;  1ZYR E;  2R93 F;  3S15 F;  3GTL F;  1WCM F;  3CQZ F;  2VUM F;  3GTK F;  1I6V E;  3HOY F;  1I3Q F;  3RZD F;  5C4J F;  2JA6 F;  1Y1V F;  4BBR F;  2NVY F;  5C44 F;  4Y7N F;  1YNJ K;  2A68 E;  1TWH F;  2JA7 F;  5IPL E;  5IYB F;  5D4D E;  4MEX E;  2BE5 E;  2WB1 I;  3GTQ F;  2E2I F;  3RZO F;  1TWF F;  4BXX F;  4BY1 F;  3S17 F;  1YNN K;  1I50 F;  4JK1 E;  2R92 F;  1SFO F;  4YFX E;  4BBS F;  4LLG E;  5M3F F; 
#chains in the Genus database with same CATH topology
 3HOV F;  4OIP E;  4Y52 F;  3M3Y E;  3FKI F;  4G7O E;  1TWG E;  3HKZ K;  3GTG E;  3S14 E;  5E17 E;  4C3H F;  4A93 E;  3S16 E;  4X6A E;  4GZY E;  4YFN E;  2PMZ K;  3S2H E;  4XLN E;  1I3Q E;  5IYC F;  2JA6 E;  4A3J F;  1Y1W F;  2NVQ F;  1SMY E;  5M5Y F;  3HOW F;  3S1M E;  2E2J E;  1Y1V E;  4A3F F;  4A3E E;  4BY7 F;  2A69 E;  5C44 E;  2YU9 E;  4Q5S E;  1TWH E;  5C3E F;  4OIN E;  5IYB E;  5D4C E;  4A3D F;  5IYD F;  3S1R F;  4C3I F;  2NVT F;  4QIW H;  1TWF E;  5M3M E;  3HOZ F;  3RZO E;  3I4N F;  4BY1 E;  3S2D E;  2E2H E;  4BXX E;  3S1N E;  5IP9 F;  4QIW K;  4A3B E;  4A3C F;  3H0G F;  5IP7 E;  2NVX E;  1HQM E;  4BBS E;  1TWC E;  2A6H E;  3HOV E;  1QKL A;  3S1Q E;  5TMC E;  2WB1 H;  4ZH4 E;  2WAQ K;  4A3G F;  4XSZ E;  3HKZ H;  3HOX F;  2JA5 E;  3I4M F;  2Y0S I;  4Q4Z E;  1TWA F;  1K83 F;  1I6H F;  4MQ9 E;  3S15 E;  2R93 E;  3GTL E;  1WCM E;  2PMZ H;  3CQZ E;  2VUM E;  3GTM F;  1DZF A;  3GTK E;  3HOY E;  1R9T F;  4A3I F;  4AYB K;  3K7A F;  4KMU E;  5IYC E;  3HOW E;  3RZD E;  5FLM F;  5C4J E;  3GTJ F;  2O5I E;  2R7Z F;  3M4O F;  3H3V F;  4BBR E;  5FJ8 F;  5E18 E;  2NVY E;  4A3M F;  4Y7N E;  4A3K F;  4MEY E;  4C3J F;  2JA7 E;  2O5J E;  5D4E E;  5C4X F;  4C2M F;  3GTQ E;  2B63 F;  2E2I E;  4OIR E;  4G7H E;  5IP9 E;  3PO3 F;  3S17 E;  3GTO F;  1I50 E;  4YG2 E;  2R92 E;  1SFO E;  3GTP F;  3M3Y F;  4LK0 E;  4OIO E;  3PO2 F;  2WAQ H;  5M3F E;  1Y1W E;  3HOU F;  1TWG F;  3GTG F;  3S14 F;  4Y52 E;  4A93 F;  3I4M E;  3FKI E;  5BYH E;  4G7Z E;  5M5X F;  4X6A F;  3S2H F;  4C3H E;  2A6E E;  4AYB H;  3S1M F;  2E2J F;  2PPB E;  4A3E F;  2NVQ E;  4A3J E;  5M5Y E;  2YU9 F;  4A3F E;  2Y0S H;  1IW7 E;  4A3M E;  4LK1 E;  4BY7 E;  2CW0 E;  5C4X E;  3EQL E;  4YFK E;  3DXJ E;  5M3M F;  5C3E E;  4KN7 E;  3S2D F;  3S1N F;  2E2H F;  4A3D E;  5M5W F;  4A3B F;  5IYD E;  3S1R E;  4C3I E;  2NVT E;  4KN4 E;  4LJZ E;  5IP7 F;  3HOZ E;  2JA8 F;  3I4N E;  3H3V G;  3WOD E;  2NVX F;  3PO3 E;  4XLP E;  4OIQ E;  1TWC F;  4XSX E;  5TMF E;  4A3L F;  4A3C E;  3H0G E;  3S16 F;  3S1Q F;  3GTP E;  3PO2 E;  2JA5 F;  1ZYR E;  3HOU E;  2R93 F;  3S15 F;  4A3G E;  3GTL F;  1WCM F;  3HOX E;  3CQZ F;  5M5X E;  2VUM F;  3GTK F;  1K83 E;  1I6V E;  1TWA E;  3HOY F;  1I6H E;  1I3Q F;  3RZD F;  5C4J F;  2JA6 F;  3GTM E;  1R9T E;  4A3I E;  1Y1V F;  3K7A E;  4BBR F;  5FLM E;  2NVY F;  5C44 F;  3GTJ E;  4Y7N F;  1YNJ K;  2A68 E;  1TWH F;  2JA7 F;  2R7Z E;  5IYB F;  5D4D E;  4MEX E;  3M4O E;  5FJ8 E;  5IPL E;  1EIK A;  2BE5 E;  2WB1 I;  4A3K E;  3GTQ F;  4C3J E;  2E2I F;  3RZO F;  1TWF F;  4BXX F;  5M5W E;  4BY1 F;  2KRX A;  4C2M E;  3S17 F;  2B63 E;  2JA8 E;  1YNN K;  1I50 F;  4JK1 E;  2R92 F;  1SFO F;  4YFX E;  4A3L E;  4BBS F;  4LLG E;  5M3F F;  3GTO E; 
#chains in the Genus database with same CATH homology
 3HOV F;  4OIP E;  4Y52 F;  3FKI F;  4G7O E;  3HKZ K;  5E17 E;  4C3H F;  4GZY E;  4YFN E;  2PMZ K;  4XLN E;  3HOW F;  5IYC F;  2NVQ F;  4A3J F;  1Y1W F;  1SMY E;  5M5Y F;  4A3F F;  4BY7 F;  2A69 E;  4Q5S E;  5C3E F;  4OIN E;  5D4C E;  4A3D F;  5IYD F;  3S1R F;  4C3I F;  2NVT F;  3HOZ F;  3I4N F;  5IP9 F;  4QIW K;  4A3C F;  3H0G F;  1HQM E;  2A6H E;  1QKL A;  5TMC E;  4ZH4 E;  2WAQ K;  4A3G F;  4XSZ E;  3HOX F;  3I4M F;  2Y0S I;  4Q4Z E;  1TWA F;  1K83 F;  1I6H F;  4MQ9 E;  3GTM F;  1R9T F;  4A3I F;  4AYB K;  3K7A F;  4KMU E;  5FLM F;  3GTJ F;  2O5I E;  2R7Z F;  3M4O F;  5FJ8 F;  5E18 E;  4A3M F;  4A3K F;  4MEY E;  4C3J F;  5C4X F;  2O5J E;  5D4E E;  4C2M F;  2B63 F;  4OIR E;  4G7H E;  3PO3 F;  3GTO F;  4YG2 E;  3GTP F;  3M3Y F;  4LK0 E;  4OIO E;  3PO2 F;  3HOU F;  1TWG F;  3GTG F;  3S14 F;  4A93 F;  5BYH E;  4G7Z E;  5M5X F;  4X6A F;  3S2H F;  2A6E E;  3S1M F;  2E2J F;  2PPB E;  4A3E F;  2YU9 F;  1IW7 E;  4LK1 E;  2CW0 E;  3EQL E;  4YFK E;  3DXJ E;  5M3M F;  4KN7 E;  3S2D F;  3S1N F;  2E2H F;  5M5W F;  4A3B F;  4KN4 E;  4LJZ E;  5IP7 F;  2JA8 F;  3H3V G;  3WOD E;  2NVX F;  4XLP E;  4OIQ E;  1TWC F;  4XSX E;  5TMF E;  4A3L F;  3S16 F;  3S1Q F;  2JA5 F;  1ZYR E;  2R93 F;  3S15 F;  3GTL F;  1WCM F;  3CQZ F;  2VUM F;  3GTK F;  1I6V E;  3HOY F;  1I3Q F;  3RZD F;  5C4J F;  2JA6 F;  1Y1V F;  4BBR F;  2NVY F;  5C44 F;  4Y7N F;  1YNJ K;  2A68 E;  1TWH F;  2JA7 F;  5IPL E;  5IYB F;  5D4D E;  4MEX E;  2BE5 E;  2WB1 I;  3GTQ F;  2E2I F;  3RZO F;  1TWF F;  4BXX F;  4BY1 F;  2KRX A;  3S17 F;  1YNN K;  1I50 F;  4JK1 E;  2R92 F;  1SFO F;  4YFX E;  4BBS F;  4LLG E;  5M3F F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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