2P8EA

Crystal structure of the serine/threonine phosphatase domain of human ppm1b
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
292
structure length
277
Chain Sequence
FLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGSRVANYCSTHLLEHITTNEDFRSVENVKNGIRTGFLKIDEYMRNFSDLRDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILADGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural genomics of protein phosphatases.
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords PPM1B beta isoform variant 6
total genus 89
structure length 277
sequence length 292
chains with identical sequence B
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2007-03-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00481 PP2C Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2p8eA00
3RT0A 3D8KA 2JFRA 3F79A 3ZT9A 2V06A 3RNRA 2POMA 2ISNA 2JFSA 3FXLA 1A6QA 3UJLB 3FXMA 3W42A 3T91A 3W41A 3MQ3A 3NMTB 5ITIA 3NMNB 3FXJA 4DS8B 2I0OA 4WVOB 2J4OA 2J82A 3JRQA 5F1MA 3FXKA 4LGBB 2IRMA 3EQ2A 2XZVA 2JFTA 3NMVB 3N3CA 4YZGA 4LG5B 1TXOA 4YZHA 3UJGB 3W45A 2CM1A 2POPA 2IQ1A 4RAFA 4DA1A 4N0GA 3ZVUB 3FXOA 4RA2A 4LGAB 3T9QA 2P8EA 3ES2A 3PU9A 3W43A 2J86A 4RAGA 3UJKA 2PNQA 3KDJB 4OICB 5D2UA 4JNDA 2PK0A 5JO1B 2I44A 3W44A 3KE6A 3KB3B 3QN1B 4LA7B 5JO2B 3W40A 2Y09A
chains in the Genus database with same CATH superfamily
3RT0A 3D8KA 2JFRA 3F79A 3ZT9A 2V06A 3RNRA 2POMA 2ISNA 2JFSA 3FXLA 1A6QA 3UJLB 3FXMA 3W42A 3T91A 4IIKA 4IIPA 3W41A 3MQ3A 3NMTB 5ITIA 3NMNB 3FXJA 4DS8B 2I0OA 4WVOB 2J4OA 2J82A 3JRQA 5F1MA 3FXKA 4LGBB 2IRMA 3EQ2A 2JFTA 3NMVB 3N3CA 4YZGA 4LG5B 1TXOA 4YZHA 3UJGB 3W45A 2CM1A 2POPA 2IQ1A 4RAFA 4DA1A 4N0GA 3ZVUB 3FXOA 4RA2A 4LGAB 3T9QA 2P8EA 3ES2A 3PU9A 3W43A 2J86A 4RAGA 3UJKA 2PNQA 5JO2B 3KDJB 4OICB 5D2UA 4JNDA 2PK0A 5JO1B 2I44A 3W44A 3KE6A 3KB3B 3QN1B 4LA7B 2XZVA 3W40A 2Y09A
chains in the Genus database with same CATH topology
3RT0A 3D8KA 2JFRA 3F79A 3ZT9A 2V06A 3RNRA 2POMA 2ISNA 2JFSA 3FXLA 1A6QA 3UJLB 3FXMA 3W42A 3T91A 3W41A 3MQ3A 3NMTB 5ITIA 3NMNB 3FXJA 4DS8B 2I0OA 4WVOB 2J4OA 2J82A 3JRQA 5F1MA 3FXKA 4LGBB 2IRMA 3EQ2A 2XZVA 2JFTA 3NMVB 3N3CA 4YZGA 4LG5B 1TXOA 4YZHA 3UJGB 3W45A 2CM1A 2POPA 2IQ1A 4RAFA 4DA1A 4N0GA 3ZVUB 3FXOA 4RA2A 4LGAB 3T9QA 2P8EA 3ES2A 3PU9A 3W43A 2J86A 4RAGA 3UJKA 2PNQA 3KDJB 4OICB 5D2UA 4JNDA 2PK0A 5JO1B 2I44A 3W44A 3KE6A 3KB3B 3QN1B 4LA7B 5JO2B 3W40A 2Y09A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3RT0 A;  3D8K A;  2JFR A;  3F79 A;  3ZT9 A;  2V06 A;  3RNR A;  2POM A;  2ISN A;  2JFS A;  3FXL A;  1A6Q A;  3UJL B;  3FXM A;  3W42 A;  3T91 A;  3W41 A;  3MQ3 A;  3NMT B;  5ITI A;  3NMN B;  3FXJ A;  4DS8 B;  2I0O A;  4WVO B;  2J4O A;  2J82 A;  3JRQ A;  5F1M A;  3FXK A;  4LGB B;  2IRM A;  3EQ2 A;  2XZV A;  2JFT A;  3NMV B;  3N3C A;  4YZG A;  4LG5 B;  1TXO A;  4YZH A;  3UJG B;  3W45 A;  2CM1 A;  2POP A;  2IQ1 A;  4RAF A;  4DA1 A;  4N0G A;  3ZVU B;  3FXO A;  4RA2 A;  4LGA B;  3T9Q A;  2P8E A;  3ES2 A;  3PU9 A;  3W43 A;  2J86 A;  4RAG A;  3UJK A;  2PNQ A;  3KDJ B;  4OIC B;  5D2U A;  4JND A;  2PK0 A;  5JO1 B;  2I44 A;  3W44 A;  3KE6 A;  3KB3 B;  3QN1 B;  4LA7 B;  5JO2 B;  3W40 A;  2Y09 A; 
#chains in the Genus database with same CATH topology
 3RT0 A;  3D8K A;  2JFR A;  3F79 A;  3ZT9 A;  2V06 A;  3RNR A;  2POM A;  2ISN A;  2JFS A;  3FXL A;  1A6Q A;  3UJL B;  3FXM A;  3W42 A;  3T91 A;  4IIK A;  4IIP A;  3W41 A;  3MQ3 A;  3NMT B;  5ITI A;  3NMN B;  3FXJ A;  4DS8 B;  2I0O A;  4WVO B;  2J4O A;  2J82 A;  3JRQ A;  5F1M A;  3FXK A;  4LGB B;  2IRM A;  3EQ2 A;  2JFT A;  3NMV B;  3N3C A;  4YZG A;  4LG5 B;  1TXO A;  4YZH A;  3UJG B;  3W45 A;  2CM1 A;  2POP A;  2IQ1 A;  4RAF A;  4DA1 A;  4N0G A;  3ZVU B;  3FXO A;  4RA2 A;  4LGA B;  3T9Q A;  2P8E A;  3ES2 A;  3PU9 A;  3W43 A;  2J86 A;  4RAG A;  3UJK A;  2PNQ A;  5JO2 B;  3KDJ B;  4OIC B;  5D2U A;  4JND A;  2PK0 A;  5JO1 B;  2I44 A;  3W44 A;  3KE6 A;  3KB3 B;  3QN1 B;  4LA7 B;  2XZV A;  3W40 A;  2Y09 A; 
#chains in the Genus database with same CATH homology
 3RT0 A;  3D8K A;  2JFR A;  3F79 A;  3ZT9 A;  2V06 A;  3RNR A;  2POM A;  2ISN A;  2JFS A;  3FXL A;  1A6Q A;  3UJL B;  3FXM A;  3W42 A;  3T91 A;  3W41 A;  3MQ3 A;  3NMT B;  5ITI A;  3NMN B;  3FXJ A;  4DS8 B;  2I0O A;  4WVO B;  2J4O A;  2J82 A;  3JRQ A;  5F1M A;  3FXK A;  4LGB B;  2IRM A;  3EQ2 A;  2XZV A;  2JFT A;  3NMV B;  3N3C A;  4YZG A;  4LG5 B;  1TXO A;  4YZH A;  3UJG B;  3W45 A;  2CM1 A;  2POP A;  2IQ1 A;  4RAF A;  4DA1 A;  4N0G A;  3ZVU B;  3FXO A;  4RA2 A;  4LGA B;  3T9Q A;  2P8E A;  3ES2 A;  3PU9 A;  3W43 A;  2J86 A;  4RAG A;  3UJK A;  2PNQ A;  3KDJ B;  4OIC B;  5D2U A;  4JND A;  2PK0 A;  5JO1 B;  2I44 A;  3W44 A;  3KE6 A;  3KB3 B;  3QN1 B;  4LA7 B;  5JO2 B;  3W40 A;  2Y09 A; 
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