2POMA

Tab1 with manganese ion
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
355
structure length
355
Chain Sequence
SWTDDLPLCHLSGVGSASNRSYSADGKGTESHPPEDSWLKFRSENNCFLYGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKSTVDGLQVTQLNVDHTTENEDELFRLSQLGLDAGKIKQVGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLYKALEAAHGPGQANQEIAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHEDMTLLVRNFGYPLG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title XIAP Induces NF-kappaB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization.
pubmed doi rcsb
molecule tags Signaling protein/metal binding protein
source organism Homo sapiens
molecule keywords Mitogen-activated protein kinase kinase kinase 7-interacting
total genus 114
structure length 355
sequence length 355
ec nomenclature
pdb deposition date 2007-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00481 PP2C Protein phosphatase 2C
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.40.10 Alpha Beta 4-Layer Sandwich Phosphatase 2c; domain 1 PPM-type phosphatase domain 2pomA00
3FXKA 3PU9A 5JO2B 2XZVA 4RA2A 3ZT9A 2PNQA 1A6QA 2PK0A 4N0GA 2POPA 4LG5B 4DS8B 4JNDA 3NMVB 4LA7B 3FXLA 3W44A 1TXOA 2CM1A 2I0OA 2J82A 2P8EA 2J4OA 2V06A 3KB3B 3W45A 3RT0A 5D2UA 3UJKA 5F1MA 3W42A 2I44A 3RNRA 2JFRA 4YZGA 3UJLB 4RAGA 3MQ3A 3T9QA 3ES2A 3W40A 3W41A 5JO1B 3JRQA 3FXOA 5ITIA 4OICB 3T91A 2POMA 4DA1A 2JFTA 3N3CA 4RAFA 3KDJB 3F79A 3KE6A 3D8KA 2JFSA 3QN1B 3UJGB 2IQ1A 2ISNA 3NMNB 2J86A 3FXJA 2Y09A 3NMTB 3EQ2A 4LGBB 2IRMA 4LGAB 3FXMA 4YZHA 4WVOB 3W43A 3ZVUB
chains in the Genus database with same CATH superfamily
3FXKA 3PU9A 5JO2B 2XZVA 4RA2A 3ZT9A 2PNQA 1A6QA 2PK0A 4N0GA 2POPA 4LG5B 4DS8B 4IIPA 4IIKA 4JNDA 3NMVB 4LA7B 3FXLA 3W44A 1TXOA 2CM1A 2I0OA 2J82A 2P8EA 2J4OA 2V06A 3KB3B 3W45A 3RT0A 5D2UA 3UJKA 5F1MA 3W42A 2I44A 3RNRA 2JFRA 4YZGA 3UJLB 4RAGA 3MQ3A 3T9QA 3ES2A 3W40A 3W41A 5JO1B 3JRQA 3FXOA 5ITIA 4OICB 3T91A 2POMA 4DA1A 2JFTA 3N3CA 4RAFA 3KDJB 3F79A 3KE6A 3D8KA 2JFSA 3QN1B 3UJGB 2IQ1A 2ISNA 3NMNB 2J86A 3FXJA 2Y09A 3NMTB 3EQ2A 4LGBB 2IRMA 4LGAB 3FXMA 4YZHA 4WVOB 3W43A 3ZVUB
chains in the Genus database with same CATH topology
3FXKA 3PU9A 5JO2B 2XZVA 4RA2A 3ZT9A 2PNQA 1A6QA 2PK0A 4N0GA 2POPA 4LG5B 4DS8B 4JNDA 3NMVB 4LA7B 3FXLA 3W44A 1TXOA 2CM1A 2I0OA 2J82A 2P8EA 2J4OA 2V06A 3KB3B 3W45A 3RT0A 5D2UA 3UJKA 5F1MA 3W42A 2I44A 3RNRA 2JFRA 4YZGA 3UJLB 4RAGA 3MQ3A 3T9QA 3ES2A 3W40A 3W41A 5JO1B 3JRQA 3FXOA 5ITIA 4OICB 3T91A 2POMA 4DA1A 2JFTA 3N3CA 4RAFA 3KDJB 3F79A 3KE6A 3D8KA 2JFSA 3QN1B 3UJGB 2IQ1A 2ISNA 3NMNB 2J86A 3FXJA 2Y09A 3NMTB 3EQ2A 4LGBB 2IRMA 4LGAB 3FXMA 4YZHA 4WVOB 3W43A 3ZVUB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FXK A;  3PU9 A;  5JO2 B;  2XZV A;  4RA2 A;  3ZT9 A;  2PNQ A;  1A6Q A;  2PK0 A;  4N0G A;  2POP A;  4LG5 B;  4DS8 B;  4JND A;  3NMV B;  4LA7 B;  3FXL A;  3W44 A;  1TXO A;  2CM1 A;  2I0O A;  2J82 A;  2P8E A;  2J4O A;  2V06 A;  3KB3 B;  3W45 A;  3RT0 A;  5D2U A;  3UJK A;  5F1M A;  3W42 A;  2I44 A;  3RNR A;  2JFR A;  4YZG A;  3UJL B;  4RAG A;  3MQ3 A;  3T9Q A;  3ES2 A;  3W40 A;  3W41 A;  5JO1 B;  3JRQ A;  3FXO A;  5ITI A;  4OIC B;  3T91 A;  2POM A;  4DA1 A;  2JFT A;  3N3C A;  4RAF A;  3KDJ B;  3F79 A;  3KE6 A;  3D8K A;  2JFS A;  3QN1 B;  3UJG B;  2IQ1 A;  2ISN A;  3NMN B;  2J86 A;  3FXJ A;  2Y09 A;  3NMT B;  3EQ2 A;  4LGB B;  2IRM A;  4LGA B;  3FXM A;  4YZH A;  4WVO B;  3W43 A;  3ZVU B; 
#chains in the Genus database with same CATH topology
 3FXK A;  3PU9 A;  5JO2 B;  2XZV A;  4RA2 A;  3ZT9 A;  2PNQ A;  1A6Q A;  2PK0 A;  4N0G A;  2POP A;  4LG5 B;  4DS8 B;  4IIP A;  4IIK A;  4JND A;  3NMV B;  4LA7 B;  3FXL A;  3W44 A;  1TXO A;  2CM1 A;  2I0O A;  2J82 A;  2P8E A;  2J4O A;  2V06 A;  3KB3 B;  3W45 A;  3RT0 A;  5D2U A;  3UJK A;  5F1M A;  3W42 A;  2I44 A;  3RNR A;  2JFR A;  4YZG A;  3UJL B;  4RAG A;  3MQ3 A;  3T9Q A;  3ES2 A;  3W40 A;  3W41 A;  5JO1 B;  3JRQ A;  3FXO A;  5ITI A;  4OIC B;  3T91 A;  2POM A;  4DA1 A;  2JFT A;  3N3C A;  4RAF A;  3KDJ B;  3F79 A;  3KE6 A;  3D8K A;  2JFS A;  3QN1 B;  3UJG B;  2IQ1 A;  2ISN A;  3NMN B;  2J86 A;  3FXJ A;  2Y09 A;  3NMT B;  3EQ2 A;  4LGB B;  2IRM A;  4LGA B;  3FXM A;  4YZH A;  4WVO B;  3W43 A;  3ZVU B; 
#chains in the Genus database with same CATH homology
 3FXK A;  3PU9 A;  5JO2 B;  2XZV A;  4RA2 A;  3ZT9 A;  2PNQ A;  1A6Q A;  2PK0 A;  4N0G A;  2POP A;  4LG5 B;  4DS8 B;  4JND A;  3NMV B;  4LA7 B;  3FXL A;  3W44 A;  1TXO A;  2CM1 A;  2I0O A;  2J82 A;  2P8E A;  2J4O A;  2V06 A;  3KB3 B;  3W45 A;  3RT0 A;  5D2U A;  3UJK A;  5F1M A;  3W42 A;  2I44 A;  3RNR A;  2JFR A;  4YZG A;  3UJL B;  4RAG A;  3MQ3 A;  3T9Q A;  3ES2 A;  3W40 A;  3W41 A;  5JO1 B;  3JRQ A;  3FXO A;  5ITI A;  4OIC B;  3T91 A;  2POM A;  4DA1 A;  2JFT A;  3N3C A;  4RAF A;  3KDJ B;  3F79 A;  3KE6 A;  3D8K A;  2JFS A;  3QN1 B;  3UJG B;  2IQ1 A;  2ISN A;  3NMN B;  2J86 A;  3FXJ A;  2Y09 A;  3NMT B;  3EQ2 A;  4LGB B;  2IRM A;  4LGA B;  3FXM A;  4YZH A;  4WVO B;  3W43 A;  3ZVU B; 
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#similar chains, but unknotted
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