2R7ZF

Cisplatin lesion containing rna polymerase ii elongation complex
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
84
structure length
84
Chain Sequence
KAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanism of transcriptional stalling at cisplatin-damaged DNA.
pubmed doi rcsb
molecule tags Transcription/dna-rna hybrid
molecule keywords 5'-D(*TP*AP*CP*TP*TP*GUP*CP*CP*CP*TP*CP*CP*TP*CP*AP*T)-3'
total genus 23
structure length 84
sequence length 84
ec nomenclature
pdb deposition date 2007-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 2r7zF00
1SFOF 4X6AF 2E2IF 2WB1I 1SMYE 2Y0SI 4A3IF 5E18E 1I6HF 1TWAF 4YFNE 3FKIF 4GZYE 4XSZE 5M3MF 4XLNE 3GTGF 2O5JE 3GTOF 5M5XF 4Y52F 2R92F 3GTLF 3GTKF 1I3QF 1TWCF 5IP7F 2NVQF 4MEXE 4JK1E 4LK0E 4XSXE 2CW0E 5IPLE 4BXXF 4C3JF 1HQME 5M5WF 4BY7F 2BE5E 4Q5SE 4ZH4E 2E2JF 4OINE 2NVXF 4LJZE 5C44F 4KMUE 4Q4ZE 1IW7E 2R93F 1TWFF 1K83F 2B63F 2A68E 3M4OF 5M3FF 3I4NF 2PMZK 3M3YF 5E17E 3S14F 4A3DF 1YNNK 4A3KF 2PPBE 4KN4E 4AYBK 4BY1F 4A93F 4KN7E 3H0GF 4G7ZE 3S1QF 3GTJF 4MQ9E 4A3GF 4G7OE 1YNJK 5IP9F 4BBRF 4A3LF 4A3EF 2VUMF 5IYDF 3RZOF 5TMFE 2E2HF 5C4JF 3GTMF 3S2DF 4C3HF 2NVYF 5D4DE 3CQZF 4OIOE 3S1RF 4A3CF 3S17F 1QKLA 3K7AF 1TWGF 4MEYE 5IYBF 2WAQK 4LLGE 1I6VE 4XLPE 5M5YF 3WODE 2JA8F 4A3BF 5IYCF 4YFXE 5TMCE 3HOUF 1I50F 4Y7NF 1Y1WF 5FLMF 5FJ8F 3GTPF 3HOWF 3S15F 5D4CE 3S1NF 4C2MF 3HOXF 2A6HE 3HOZF 3HKZK 2JA6F 2A69E 2NVTF 5D4EE 5C3EF 2R7ZF 4A3FF 4BBSF 4OIQE 2JA7F 3S1MF 3I4MF 2O5IE 2YU9F 3PO3F 1TWHF 1ZYRE 3PO2F 4YFKE 4C3IF 3HOVF 3S16F 4OIPE 4LK1E 3H3VG 3RZDF 4A3MF 1R9TF 3DXJE 5BYHE 3HOYF 4A3JF 3EQLE 1WCMF 2JA5F 4YG2E 1Y1VF 4G7HE 5C4XF 3GTQF 3S2HF 4OIRE 2A6EE
chains in the Genus database with same CATH superfamily
4X6AE 1SFOF 3HOZE 4X6AF 2E2IF 2WB1I 2NVTE 1SMYE 5C3EE 2R7ZE 4A3FE 4BBSE 2Y0SI 1I6HE 4A3IF 2JA7E 3I4ME 5E18E 1I6HF 2O5JE 1TWAE 1TWAF 4YFNE 3FKIF 5M3ME 4GZYE 4XSZE 1TWHE 5M3MF 4XLNE 3PO2E 3GTGF 3GTOE 4QIWH 4C3IE 5M5XE 3GTOF 3GTKE 5M5XF 4Y52F 2R92F 3GTLF 3GTKF 4Y52E 1I3QF 1TWCF 5IP7E 3RZDE 4A3ME 5IP7F 1R9TE 4MEXE 2NVQF 4JK1E 3HOWE 3HOYE 4LK0E 4XSXE 2CW0E 4A3JE 4BXXE 5IPLE 4BXXF 1WCME 1HQME 4C3JF 1Y1VE 2JA5E 5M5WF 4BY7E 4BY7F 2BE5E 3GTQE 5C4XE 4Q5SE 1EIKA 3S2HE 4ZH4E 2E2JF 4OINE 2NVXE 1SFOE 4LJZE 5C44E 2NVXF 5C44F 4KMUE 1TWFE 4Q4ZE 1IW7E 1K83E 1TWFF 3HKZH 1K83F 2E2IE 2B63E 2B63F 2R93F 4A3IE 3FKIE 2A68E 3I4NE 3M4OF 5M3FF 3GTGE 3I4NF 3M3YE 2PMZK 3M3YF 5E17E 3S14F 3GTLE 2R92E 4A3DF 4A3KE 1I3QE 1YNNK 1TWCE 4A3KF 2PPBE 4KN4E 4AYBK 4A93E 4BY1F 4A93F 2NVQE 4KN7E 3H0GF 4G7ZE 3S1QF 3GTJE 3GTJF 4MQ9E 4A3GF 4G7OE 4C3JE 1YNJK 5IP9F 4BBRE 5M5WE 4BBRF 4A3LE 3H3VF 4A3EF 4A3LF 2VUME 5IYDE 2E2JE 2VUMF 3RZOE 5IYDF 3RZOF 5TMFE 2E2HE 2E2HF 5C4JF 3GTMF 3S2DF 2R93E 2NVYE 4C3HF 2NVYF 5D4DE 3CQZF 4OIOE 3S1RF 4QIWK 4A3CE 4A3CF 3M4OE 3K7AE 1TWGE 5IYBE 1QKLA 3K7AF 1TWGF 4MEYE 5IYBF 2WAQK 5M3FE 4LLGE 3S17F 1I6VE 3S14E 4A3DE 5M5YE 4A3BE 4XLPE 2JA8E 5M5YF 3WODE 2JA8F 5IYCE 4A3BF 4BY1E 5IYCF 4YFXE 1I50E 5TMCE 4Y7NE 3HOUF 1I50F 4Y7NF 3H0GE 5FLMF 5FJ8F 1Y1WF 3GTPF 3HOWF 3S1QE 3S15F 3S1NE 5D4CE 4A3GE 3S1NF 5IP9E 4C2ME 4C2MF 3HOXE 3HOXF 4A3EE 2A6HE 3HOZF 4BBSF 3HKZK 2JA6E 2JA6F 2A69E 2NVTF 5C4JE 5D4EE 5C3EF 2R7ZF 4A3FF 3GTME 3S1ME 3S2DE 4OIQE 2JA7F 4C3HE 2YU9E 3I4MF 2O5IE 2YU9F 3S1MF 3PO3E 3PO3F 3CQZE 1DZFA 1TWHF 1ZYRE 3S1RE 3PO2F 2KRXA 4YFKE 4C3IF 3HOVE 3S16E 3HOVF 3S17E 3S16F 2WAQH 4OIPE 2PMZH 4LK1E 3H3VG 3RZDF 4A3MF 1R9TF 3DXJE 5BYHE 3HOYF 4AYBH 2WB1H 4A3JF 3HOUE 1Y1WE 3EQLE 1WCMF 5FLME 2Y0SH 1Y1VF 4YG2E 5FJ8E 2JA5F 3GTPE 3S15E 4G7HE 5C4XF 3GTQF 3S2HF 4OIRE 2A6EE
chains in the Genus database with same CATH topology
1SFOF 4X6AF 2E2IF 2WB1I 1SMYE 2Y0SI 4A3IF 5E18E 1I6HF 1TWAF 4YFNE 3FKIF 4GZYE 4XSZE 5M3MF 4XLNE 3GTGF 2O5JE 3GTOF 5M5XF 4Y52F 2R92F 3GTLF 3GTKF 1I3QF 1TWCF 5IP7F 2NVQF 4MEXE 4JK1E 4LK0E 4XSXE 2CW0E 5IPLE 4BXXF 4C3JF 1HQME 5M5WF 4BY7F 2BE5E 4Q5SE 4ZH4E 2E2JF 4OINE 2NVXF 4LJZE 5C44F 4KMUE 4Q4ZE 1IW7E 2R93F 1TWFF 1K83F 2B63F 2A68E 3M4OF 5M3FF 3I4NF 2PMZK 3M3YF 5E17E 3S14F 4A3DF 1YNNK 4A3KF 2PPBE 4KN4E 4AYBK 4BY1F 4A93F 4KN7E 3H0GF 4G7ZE 3S1QF 3GTJF 4MQ9E 4A3GF 4G7OE 1YNJK 5IP9F 4BBRF 4A3LF 4A3EF 2VUMF 5IYDF 3RZOF 5TMFE 2E2HF 5C4JF 3GTMF 3S2DF 4C3HF 2NVYF 5D4DE 3CQZF 4OIOE 3S1RF 4QIWK 4A3CF 3S17F 1QKLA 3K7AF 1TWGF 4MEYE 5IYBF 2WAQK 4LLGE 1I6VE 4XLPE 5M5YF 3WODE 2JA8F 4A3BF 5IYCF 4YFXE 5TMCE 3HOUF 1I50F 4Y7NF 1Y1WF 5FLMF 5FJ8F 3GTPF 3HOWF 3S15F 5D4CE 3S1NF 4C2MF 3HOXF 2A6HE 3HOZF 3HKZK 2JA6F 2A69E 2NVTF 5D4EE 5C3EF 2R7ZF 4A3FF 4BBSF 4OIQE 2JA7F 3S1MF 3I4MF 2O5IE 2YU9F 3PO3F 1TWHF 1ZYRE 3PO2F 2KRXA 4YFKE 4C3IF 3HOVF 3S16F 4OIPE 4LK1E 3H3VG 3RZDF 4A3MF 1R9TF 3DXJE 5BYHE 3HOYF 4A3JF 3EQLE 1WCMF 2JA5F 4YG2E 1Y1VF 4G7HE 5C4XF 3GTQF 3S2HF 4OIRE 2A6EE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SFO F;  4X6A F;  2E2I F;  2WB1 I;  1SMY E;  2Y0S I;  4A3I F;  5E18 E;  1I6H F;  1TWA F;  4YFN E;  3FKI F;  4GZY E;  4XSZ E;  5M3M F;  4XLN E;  3GTG F;  2O5J E;  3GTO F;  5M5X F;  4Y52 F;  2R92 F;  3GTL F;  3GTK F;  1I3Q F;  1TWC F;  5IP7 F;  2NVQ F;  4MEX E;  4JK1 E;  4LK0 E;  4XSX E;  2CW0 E;  5IPL E;  4BXX F;  4C3J F;  1HQM E;  5M5W F;  4BY7 F;  2BE5 E;  4Q5S E;  4ZH4 E;  2E2J F;  4OIN E;  2NVX F;  4LJZ E;  5C44 F;  4KMU E;  4Q4Z E;  1IW7 E;  2R93 F;  1TWF F;  1K83 F;  2B63 F;  2A68 E;  3M4O F;  5M3F F;  3I4N F;  2PMZ K;  3M3Y F;  5E17 E;  3S14 F;  4A3D F;  1YNN K;  4A3K F;  2PPB E;  4KN4 E;  4AYB K;  4BY1 F;  4A93 F;  4KN7 E;  3H0G F;  4G7Z E;  3S1Q F;  3GTJ F;  4MQ9 E;  4A3G F;  4G7O E;  1YNJ K;  5IP9 F;  4BBR F;  4A3L F;  4A3E F;  2VUM F;  5IYD F;  3RZO F;  5TMF E;  2E2H F;  5C4J F;  3GTM F;  3S2D F;  4C3H F;  2NVY F;  5D4D E;  3CQZ F;  4OIO E;  3S1R F;  4A3C F;  3S17 F;  1QKL A;  3K7A F;  1TWG F;  4MEY E;  5IYB F;  2WAQ K;  4LLG E;  1I6V E;  4XLP E;  5M5Y F;  3WOD E;  2JA8 F;  4A3B F;  5IYC F;  4YFX E;  5TMC E;  3HOU F;  1I50 F;  4Y7N F;  1Y1W F;  5FLM F;  5FJ8 F;  3GTP F;  3HOW F;  3S15 F;  5D4C E;  3S1N F;  4C2M F;  3HOX F;  2A6H E;  3HOZ F;  3HKZ K;  2JA6 F;  2A69 E;  2NVT F;  5D4E E;  5C3E F;  2R7Z F;  4A3F F;  4BBS F;  4OIQ E;  2JA7 F;  3S1M F;  3I4M F;  2O5I E;  2YU9 F;  3PO3 F;  1TWH F;  1ZYR E;  3PO2 F;  4YFK E;  4C3I F;  3HOV F;  3S16 F;  4OIP E;  4LK1 E;  3H3V G;  3RZD F;  4A3M F;  1R9T F;  3DXJ E;  5BYH E;  3HOY F;  4A3J F;  3EQL E;  1WCM F;  2JA5 F;  4YG2 E;  1Y1V F;  4G7H E;  5C4X F;  3GTQ F;  3S2H F;  4OIR E;  2A6E E; 
#chains in the Genus database with same CATH topology
 4X6A E;  1SFO F;  3HOZ E;  4X6A F;  2E2I F;  2WB1 I;  2NVT E;  1SMY E;  5C3E E;  2R7Z E;  4A3F E;  4BBS E;  2Y0S I;  1I6H E;  4A3I F;  2JA7 E;  3I4M E;  5E18 E;  1I6H F;  2O5J E;  1TWA E;  1TWA F;  4YFN E;  3FKI F;  5M3M E;  4GZY E;  4XSZ E;  1TWH E;  5M3M F;  4XLN E;  3PO2 E;  3GTG F;  3GTO E;  4QIW H;  4C3I E;  5M5X E;  3GTO F;  3GTK E;  5M5X F;  4Y52 F;  2R92 F;  3GTL F;  3GTK F;  4Y52 E;  1I3Q F;  1TWC F;  5IP7 E;  3RZD E;  4A3M E;  5IP7 F;  1R9T E;  4MEX E;  2NVQ F;  4JK1 E;  3HOW E;  3HOY E;  4LK0 E;  4XSX E;  2CW0 E;  4A3J E;  4BXX E;  5IPL E;  4BXX F;  1WCM E;  1HQM E;  4C3J F;  1Y1V E;  2JA5 E;  5M5W F;  4BY7 E;  4BY7 F;  2BE5 E;  3GTQ E;  5C4X E;  4Q5S E;  1EIK A;  3S2H E;  4ZH4 E;  2E2J F;  4OIN E;  2NVX E;  1SFO E;  4LJZ E;  5C44 E;  2NVX F;  5C44 F;  4KMU E;  1TWF E;  4Q4Z E;  1IW7 E;  1K83 E;  1TWF F;  3HKZ H;  1K83 F;  2E2I E;  2B63 E;  2B63 F;  2R93 F;  4A3I E;  3FKI E;  2A68 E;  3I4N E;  3M4O F;  5M3F F;  3GTG E;  3I4N F;  3M3Y E;  2PMZ K;  3M3Y F;  5E17 E;  3S14 F;  3GTL E;  2R92 E;  4A3D F;  4A3K E;  1I3Q E;  1YNN K;  1TWC E;  4A3K F;  2PPB E;  4KN4 E;  4AYB K;  4A93 E;  4BY1 F;  4A93 F;  2NVQ E;  4KN7 E;  3H0G F;  4G7Z E;  3S1Q F;  3GTJ E;  3GTJ F;  4MQ9 E;  4A3G F;  4G7O E;  4C3J E;  1YNJ K;  5IP9 F;  4BBR E;  5M5W E;  4BBR F;  4A3L E;  3H3V F;  4A3E F;  4A3L F;  2VUM E;  5IYD E;  2E2J E;  2VUM F;  3RZO E;  5IYD F;  3RZO F;  5TMF E;  2E2H E;  2E2H F;  5C4J F;  3GTM F;  3S2D F;  2R93 E;  2NVY E;  4C3H F;  2NVY F;  5D4D E;  3CQZ F;  4OIO E;  3S1R F;  4QIW K;  4A3C E;  4A3C F;  3M4O E;  3K7A E;  1TWG E;  5IYB E;  1QKL A;  3K7A F;  1TWG F;  4MEY E;  5IYB F;  2WAQ K;  5M3F E;  4LLG E;  3S17 F;  1I6V E;  3S14 E;  4A3D E;  5M5Y E;  4A3B E;  4XLP E;  2JA8 E;  5M5Y F;  3WOD E;  2JA8 F;  5IYC E;  4A3B F;  4BY1 E;  5IYC F;  4YFX E;  1I50 E;  5TMC E;  4Y7N E;  3HOU F;  1I50 F;  4Y7N F;  3H0G E;  5FLM F;  5FJ8 F;  1Y1W F;  3GTP F;  3HOW F;  3S1Q E;  3S15 F;  3S1N E;  5D4C E;  4A3G E;  3S1N F;  5IP9 E;  4C2M E;  4C2M F;  3HOX E;  3HOX F;  4A3E E;  2A6H E;  3HOZ F;  4BBS F;  3HKZ K;  2JA6 E;  2JA6 F;  2A69 E;  2NVT F;  5C4J E;  5D4E E;  5C3E F;  2R7Z F;  4A3F F;  3GTM E;  3S1M E;  3S2D E;  4OIQ E;  2JA7 F;  4C3H E;  2YU9 E;  3I4M F;  2O5I E;  2YU9 F;  3S1M F;  3PO3 E;  3PO3 F;  3CQZ E;  1DZF A;  1TWH F;  1ZYR E;  3S1R E;  3PO2 F;  2KRX A;  4YFK E;  4C3I F;  3HOV E;  3S16 E;  3HOV F;  3S17 E;  3S16 F;  2WAQ H;  4OIP E;  2PMZ H;  4LK1 E;  3H3V G;  3RZD F;  4A3M F;  1R9T F;  3DXJ E;  5BYH E;  3HOY F;  4AYB H;  2WB1 H;  4A3J F;  3HOU E;  1Y1W E;  3EQL E;  1WCM F;  5FLM E;  2Y0S H;  1Y1V F;  4YG2 E;  5FJ8 E;  2JA5 F;  3GTP E;  3S15 E;  4G7H E;  5C4X F;  3GTQ F;  3S2H F;  4OIR E;  2A6E E; 
#chains in the Genus database with same CATH homology
 1SFO F;  4X6A F;  2E2I F;  2WB1 I;  1SMY E;  2Y0S I;  4A3I F;  5E18 E;  1I6H F;  1TWA F;  4YFN E;  3FKI F;  4GZY E;  4XSZ E;  5M3M F;  4XLN E;  3GTG F;  2O5J E;  3GTO F;  5M5X F;  4Y52 F;  2R92 F;  3GTL F;  3GTK F;  1I3Q F;  1TWC F;  5IP7 F;  2NVQ F;  4MEX E;  4JK1 E;  4LK0 E;  4XSX E;  2CW0 E;  5IPL E;  4BXX F;  4C3J F;  1HQM E;  5M5W F;  4BY7 F;  2BE5 E;  4Q5S E;  4ZH4 E;  2E2J F;  4OIN E;  2NVX F;  4LJZ E;  5C44 F;  4KMU E;  4Q4Z E;  1IW7 E;  2R93 F;  1TWF F;  1K83 F;  2B63 F;  2A68 E;  3M4O F;  5M3F F;  3I4N F;  2PMZ K;  3M3Y F;  5E17 E;  3S14 F;  4A3D F;  1YNN K;  4A3K F;  2PPB E;  4KN4 E;  4AYB K;  4BY1 F;  4A93 F;  4KN7 E;  3H0G F;  4G7Z E;  3S1Q F;  3GTJ F;  4MQ9 E;  4A3G F;  4G7O E;  1YNJ K;  5IP9 F;  4BBR F;  4A3L F;  4A3E F;  2VUM F;  5IYD F;  3RZO F;  5TMF E;  2E2H F;  5C4J F;  3GTM F;  3S2D F;  4C3H F;  2NVY F;  5D4D E;  3CQZ F;  4OIO E;  3S1R F;  4QIW K;  4A3C F;  3S17 F;  1QKL A;  3K7A F;  1TWG F;  4MEY E;  5IYB F;  2WAQ K;  4LLG E;  1I6V E;  4XLP E;  5M5Y F;  3WOD E;  2JA8 F;  4A3B F;  5IYC F;  4YFX E;  5TMC E;  3HOU F;  1I50 F;  4Y7N F;  1Y1W F;  5FLM F;  5FJ8 F;  3GTP F;  3HOW F;  3S15 F;  5D4C E;  3S1N F;  4C2M F;  3HOX F;  2A6H E;  3HOZ F;  3HKZ K;  2JA6 F;  2A69 E;  2NVT F;  5D4E E;  5C3E F;  2R7Z F;  4A3F F;  4BBS F;  4OIQ E;  2JA7 F;  3S1M F;  3I4M F;  2O5I E;  2YU9 F;  3PO3 F;  1TWH F;  1ZYR E;  3PO2 F;  2KRX A;  4YFK E;  4C3I F;  3HOV F;  3S16 F;  4OIP E;  4LK1 E;  3H3V G;  3RZD F;  4A3M F;  1R9T F;  3DXJ E;  5BYH E;  3HOY F;  4A3J F;  3EQL E;  1WCM F;  2JA5 F;  4YG2 E;  1Y1V F;  4G7H E;  5C4X F;  3GTQ F;  3S2H F;  4OIR E;  2A6E E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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