2R92E

Elongation complex of rna polymerase ii with artificial rdrp scaffold
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular basis of RNA-dependent RNA polymerase II activity.
pubmed doi rcsb
molecule tags Transferase/rna
molecule keywords RNA (5'-R(*UP*GP*CP*AP*UP*AP*AP*AP*GP*AP*CP*CP*AP*GP*GP*C)-3
total genus 50
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2007-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 2r92E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 2r92E02
3S1NE 3HOXE 1EIKA 4A3EE 1K83E 4A3JE 1TWAE 4C3JE 4A3FE 4A3IE 2E2JE 1TWFE 3HOWE 4A3BE 4A3LE 5M5XE 2NVYE 3K7AE 3HOUE 2R93E 3HKZH 2R92E 2VUME 3GTKE 3GTME 1TWCE 3S16E 3I4ME 1WCME 1Y1VE 3HOVE 5IYCE 4QIWH 5IYBE 3S17E 4A3KE 5C3EE 4BY7E 3GTPE 5C4XE 1DZFA 4C2ME 3CQZE 3PO2E 2JA5E 3HOYE 4BBSE 3H0GE 4C3HE 2Y0SH 4X6AE 4BBRE 5C44E 5FJ8E 2E2HE 2YU9E 5IYDE 3GTJE 1SFOE 1I6HE 4AYBH 1I50E 5M5YE 3RZOE 2E2IE 4Y7NE 5M5WE 5M3FE 2JA6E 2NVXE 2WB1H 3HOZE 2B63E 3S2HE 3RZDE 1TWGE 3S15E 2JA8E 5IP9E 2NVQE 3S1RE 3I4NE 3GTQE 4C3IE 1I3QE 2JA7E 3H3VF 4A3ME 1R9TE 5M3ME 3PO3E 3GTGE 2NVTE 3S1ME 3S2DE 4Y52E 2R7ZE 1Y1WE 3GTLE 4A93E 5C4JE 4BXXE 3S1QE 2WAQH 1TWHE 5IP7E 3S14E 4A3CE 3M3YE 3M4OE 3GTOE 4BY1E 2PMZH 4A3DE 5FLME 3FKIE 4A3GE
chains in the Genus database with same CATH superfamily
2KRXA 4LK0E 4Q4ZE 5M5WF 3S1NE 1YNJK 3HOXE 5M3FF 4A3EE 4Y52F 1K83E 2JA6F 1EIKA 4A3JE 1TWAE 4C3JE 4A3FE 4A3IE 2E2JE 1QKLA 2NVXF 1TWFE 2R7ZF 2B63F 3HOWE 4A3BE 4A3LE 5M5XE 2NVYE 3RZDF 3GTLF 1TWGF 3S2HF 3S15F 3K7AE 2JA8F 3S14F 4AYBK 3HOUE 2R93E 5IP9F 2NVQF 3GTOF 3S1RF 4G7HE 3I4NF 3HKZH 4BY1F 2R92E 4C3IF 2VUME 3GTKE 1I3QF 4A3DF 4XLNE 4YG2E 2O5JE 3GTME 4OIRE 1TWCE 3S16E 2JA7F 5IPLE 4MEXE 3I4ME 1WCME 2A69E 1Y1VE 2A6EE 3HOVE 5IYCE 4A3MF 3HOXF 4QIWH 5IYBE 3S17E 5M3MF 4A3IF 4A3KE 4C3JF 4A3FF 1R9TF 3PO3F 5C3EE 4GZYE 2NVTF 4BY7E 5M5XF 3GTPE 5C4XE 1DZFA 4C2ME 4XSZE 4G7ZE 3S1MF 3S2DF 4YFNE 2R93F 3CQZE 1SMYE 4OIPE 3PO2E 2VUMF 2JA5E 5E18E 3HOYE 4BBSE 1Y1WF 4A93F 3DXJE 5C4JF 2Y0SI 1Y1VF 4BXXF 3H0GE 4LK1E 2BE5E 5IYCF 3S1QF 1TWHF 4C3HE 5IP7F 4A3CF 3M4OF 2Y0SH 3M3YF 3S17F 2A68E 4A3KF 4X6AE 4BBRE 4YFKE 5TMFE 4BY7F 5FLMF 3FKIF 4A3GF 3HKZK 5C44E 4ZH4E 5FJ8E 2E2HE 2YU9E 5IYDE 3S1NF 4A3EF 1K83F 5E17E 3GTJE 1TWAF 4A3JF 2E2JF 2JA5F 1SFOE 1TWFF 1I6HE 2WAQK 3HOWF 4A3BF 4A3LF 2NVYF 3K7AF 4OIQE 4OIOE 4AYBH 4C3HF 2PMZK 1I50E 5BYHE 3HOUF 5M5YE 4MQ9E 3RZOE 2R92F 2E2IE 3GTKF 4Y7NE 2WB1I 5M5WE 5M3FE 1TWCF 3GTMF 3S16F 2JA6E 3I4MF 1WCMF 2YU9F 2NVXE 2WB1H 3HOVF 5D4EE 3HOZE 2B63E 3S2HE 3EQLE 3RZDE 5IYBF 1TWGE 3S15E 2JA8E 5C3EF 1I6HF 5IP9E 3GTPF 2NVQE 5C4XF 3S1RE 3I4NE 2O5IE 3GTQE 4C2MF 4C3IE 1I3QE 4YFXE 5M5YF 2JA7E 3CQZF 3PO2F 4KMUE 3H3VF 5TMCE 4A3ME 3HOYF 1HQME 4BBSF 2A6HE 1R9TE 4QIWK 5M3ME 4G7OE 3PO3E 3H0GF 3GTGE 2NVTE 4JK1E 4KN7E 4KN4E 3HOZF 4Q5SE 3H3VG 4XSXE 4BBRF 3S1ME 3S2DE 4X6AF 1IW7E 3WODE 3GTQF 4Y52E 2CW0E 5C44F 5FJ8F 2E2HF 2R7ZE 1I6VE 5IYDF 4LLGE 1Y1WE 3GTLE 4A93E 1ZYRE 5C4JE 3GTJF 2PPBE 1YNNK 4BXXE 5D4DE 1SFOF 3S1QE 2WAQH 1TWHE 5IP7E 3S14E 4A3CE 4XLPE 4OINE 3M3YE 3M4OE 3GTOE 4BY1E 2PMZH 4LJZE 5D4CE 3GTGF 4A3DE 1I50F 5FLME 3FKIE 3RZOF 4MEYE 4A3GE 2E2IF 4Y7NF
chains in the Genus database with same CATH topology
3S1NE 3HOXE 1EIKA 4A3EE 1K83E 4A3JE 1TWAE 4C3JE 4A3FE 4A3IE 2E2JE 1TWFE 3HOWE 4A3BE 4A3LE 5M5XE 2NVYE 3K7AE 3HOUE 2R93E 3HKZH 2R92E 2VUME 3GTKE 3GTME 1TWCE 3S16E 3I4ME 1WCME 1Y1VE 3HOVE 5IYCE 4QIWH 5IYBE 3S17E 4A3KE 5C3EE 4BY7E 3GTPE 5C4XE 1DZFA 4C2ME 3CQZE 3PO2E 2JA5E 3HOYE 4BBSE 3H0GE 4C3HE 2Y0SH 4X6AE 4BBRE 5C44E 5FJ8E 2E2HE 2YU9E 5IYDE 3GTJE 1SFOE 1I6HE 4AYBH 1I50E 5M5YE 3RZOE 2E2IE 4Y7NE 5M5WE 5M3FE 2JA6E 2NVXE 2WB1H 3HOZE 2B63E 3S2HE 3RZDE 1TWGE 3S15E 2JA8E 5IP9E 2NVQE 3S1RE 3I4NE 3GTQE 4C3IE 1I3QE 2JA7E 3H3VF 4A3ME 1R9TE 5M3ME 3PO3E 3GTGE 2NVTE 3S1ME 3S2DE 4Y52E 2R7ZE 1Y1WE 3GTLE 4A93E 5C4JE 4BXXE 3S1QE 2WAQH 1TWHE 5IP7E 3S14E 4A3CE 3M3YE 3M4OE 3GTOE 4BY1E 2PMZH 4A3DE 5FLME 3FKIE 4A3GE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S1N E;  3HOX E;  1EIK A;  4A3E E;  1K83 E;  4A3J E;  1TWA E;  4C3J E;  4A3F E;  4A3I E;  2E2J E;  1TWF E;  3HOW E;  4A3B E;  4A3L E;  5M5X E;  2NVY E;  3K7A E;  3HOU E;  2R93 E;  3HKZ H;  2R92 E;  2VUM E;  3GTK E;  3GTM E;  1TWC E;  3S16 E;  3I4M E;  1WCM E;  1Y1V E;  3HOV E;  5IYC E;  4QIW H;  5IYB E;  3S17 E;  4A3K E;  5C3E E;  4BY7 E;  3GTP E;  5C4X E;  1DZF A;  4C2M E;  3CQZ E;  3PO2 E;  2JA5 E;  3HOY E;  4BBS E;  3H0G E;  4C3H E;  2Y0S H;  4X6A E;  4BBR E;  5C44 E;  5FJ8 E;  2E2H E;  2YU9 E;  5IYD E;  3GTJ E;  1SFO E;  1I6H E;  4AYB H;  1I50 E;  5M5Y E;  3RZO E;  2E2I E;  4Y7N E;  5M5W E;  5M3F E;  2JA6 E;  2NVX E;  2WB1 H;  3HOZ E;  2B63 E;  3S2H E;  3RZD E;  1TWG E;  3S15 E;  2JA8 E;  5IP9 E;  2NVQ E;  3S1R E;  3I4N E;  3GTQ E;  4C3I E;  1I3Q E;  2JA7 E;  3H3V F;  4A3M E;  1R9T E;  5M3M E;  3PO3 E;  3GTG E;  2NVT E;  3S1M E;  3S2D E;  4Y52 E;  2R7Z E;  1Y1W E;  3GTL E;  4A93 E;  5C4J E;  4BXX E;  3S1Q E;  2WAQ H;  1TWH E;  5IP7 E;  3S14 E;  4A3C E;  3M3Y E;  3M4O E;  3GTO E;  4BY1 E;  2PMZ H;  4A3D E;  5FLM E;  3FKI E;  4A3G E; 
#chains in the Genus database with same CATH topology
 2KRX A;  4LK0 E;  4Q4Z E;  5M5W F;  3S1N E;  1YNJ K;  3HOX E;  5M3F F;  4A3E E;  4Y52 F;  1K83 E;  2JA6 F;  1EIK A;  4A3J E;  1TWA E;  4C3J E;  4A3F E;  4A3I E;  2E2J E;  1QKL A;  2NVX F;  1TWF E;  2R7Z F;  2B63 F;  3HOW E;  4A3B E;  4A3L E;  5M5X E;  2NVY E;  3RZD F;  3GTL F;  1TWG F;  3S2H F;  3S15 F;  3K7A E;  2JA8 F;  3S14 F;  4AYB K;  3HOU E;  2R93 E;  5IP9 F;  2NVQ F;  3GTO F;  3S1R F;  4G7H E;  3I4N F;  3HKZ H;  4BY1 F;  2R92 E;  4C3I F;  2VUM E;  3GTK E;  1I3Q F;  4A3D F;  4XLN E;  4YG2 E;  2O5J E;  3GTM E;  4OIR E;  1TWC E;  3S16 E;  2JA7 F;  5IPL E;  4MEX E;  3I4M E;  1WCM E;  2A69 E;  1Y1V E;  2A6E E;  3HOV E;  5IYC E;  4A3M F;  3HOX F;  4QIW H;  5IYB E;  3S17 E;  5M3M F;  4A3I F;  4A3K E;  4C3J F;  4A3F F;  1R9T F;  3PO3 F;  5C3E E;  4GZY E;  2NVT F;  4BY7 E;  5M5X F;  3GTP E;  5C4X E;  1DZF A;  4C2M E;  4XSZ E;  4G7Z E;  3S1M F;  3S2D F;  4YFN E;  2R93 F;  3CQZ E;  1SMY E;  4OIP E;  3PO2 E;  2VUM F;  2JA5 E;  5E18 E;  3HOY E;  4BBS E;  1Y1W F;  4A93 F;  3DXJ E;  5C4J F;  2Y0S I;  1Y1V F;  4BXX F;  3H0G E;  4LK1 E;  2BE5 E;  5IYC F;  3S1Q F;  1TWH F;  4C3H E;  5IP7 F;  4A3C F;  3M4O F;  2Y0S H;  3M3Y F;  3S17 F;  2A68 E;  4A3K F;  4X6A E;  4BBR E;  4YFK E;  5TMF E;  4BY7 F;  5FLM F;  3FKI F;  4A3G F;  3HKZ K;  5C44 E;  4ZH4 E;  5FJ8 E;  2E2H E;  2YU9 E;  5IYD E;  3S1N F;  4A3E F;  1K83 F;  5E17 E;  3GTJ E;  1TWA F;  4A3J F;  2E2J F;  2JA5 F;  1SFO E;  1TWF F;  1I6H E;  2WAQ K;  3HOW F;  4A3B F;  4A3L F;  2NVY F;  3K7A F;  4OIQ E;  4OIO E;  4AYB H;  4C3H F;  2PMZ K;  1I50 E;  5BYH E;  3HOU F;  5M5Y E;  4MQ9 E;  3RZO E;  2R92 F;  2E2I E;  3GTK F;  4Y7N E;  2WB1 I;  5M5W E;  5M3F E;  1TWC F;  3GTM F;  3S16 F;  2JA6 E;  3I4M F;  1WCM F;  2YU9 F;  2NVX E;  2WB1 H;  3HOV F;  5D4E E;  3HOZ E;  2B63 E;  3S2H E;  3EQL E;  3RZD E;  5IYB F;  1TWG E;  3S15 E;  2JA8 E;  5C3E F;  1I6H F;  5IP9 E;  3GTP F;  2NVQ E;  5C4X F;  3S1R E;  3I4N E;  2O5I E;  3GTQ E;  4C2M F;  4C3I E;  1I3Q E;  4YFX E;  5M5Y F;  2JA7 E;  3CQZ F;  3PO2 F;  4KMU E;  3H3V F;  5TMC E;  4A3M E;  3HOY F;  1HQM E;  4BBS F;  2A6H E;  1R9T E;  4QIW K;  5M3M E;  4G7O E;  3PO3 E;  3H0G F;  3GTG E;  2NVT E;  4JK1 E;  4KN7 E;  4KN4 E;  3HOZ F;  4Q5S E;  3H3V G;  4XSX E;  4BBR F;  3S1M E;  3S2D E;  4X6A F;  1IW7 E;  3WOD E;  3GTQ F;  4Y52 E;  2CW0 E;  5C44 F;  5FJ8 F;  2E2H F;  2R7Z E;  1I6V E;  5IYD F;  4LLG E;  1Y1W E;  3GTL E;  4A93 E;  1ZYR E;  5C4J E;  3GTJ F;  2PPB E;  1YNN K;  4BXX E;  5D4D E;  1SFO F;  3S1Q E;  2WAQ H;  1TWH E;  5IP7 E;  3S14 E;  4A3C E;  4XLP E;  4OIN E;  3M3Y E;  3M4O E;  3GTO E;  4BY1 E;  2PMZ H;  4LJZ E;  5D4C E;  3GTG F;  4A3D E;  1I50 F;  5FLM E;  3FKI E;  3RZO F;  4MEY E;  4A3G E;  2E2I F;  4Y7N F; 
#chains in the Genus database with same CATH homology
 3S1N E;  3HOX E;  1EIK A;  4A3E E;  1K83 E;  4A3J E;  1TWA E;  4C3J E;  4A3F E;  4A3I E;  2E2J E;  1TWF E;  3HOW E;  4A3B E;  4A3L E;  5M5X E;  2NVY E;  3K7A E;  3HOU E;  2R93 E;  3HKZ H;  2R92 E;  2VUM E;  3GTK E;  3GTM E;  1TWC E;  3S16 E;  3I4M E;  1WCM E;  1Y1V E;  3HOV E;  5IYC E;  4QIW H;  5IYB E;  3S17 E;  4A3K E;  5C3E E;  4BY7 E;  3GTP E;  5C4X E;  1DZF A;  4C2M E;  3CQZ E;  3PO2 E;  2JA5 E;  3HOY E;  4BBS E;  3H0G E;  4C3H E;  2Y0S H;  4X6A E;  4BBR E;  5C44 E;  5FJ8 E;  2E2H E;  2YU9 E;  5IYD E;  3GTJ E;  1SFO E;  1I6H E;  4AYB H;  1I50 E;  5M5Y E;  3RZO E;  2E2I E;  4Y7N E;  5M5W E;  5M3F E;  2JA6 E;  2NVX E;  2WB1 H;  3HOZ E;  2B63 E;  3S2H E;  3RZD E;  1TWG E;  3S15 E;  2JA8 E;  5IP9 E;  2NVQ E;  3S1R E;  3I4N E;  3GTQ E;  4C3I E;  1I3Q E;  2JA7 E;  3H3V F;  4A3M E;  1R9T E;  5M3M E;  3PO3 E;  3GTG E;  2NVT E;  3S1M E;  3S2D E;  4Y52 E;  2R7Z E;  1Y1W E;  3GTL E;  4A93 E;  5C4J E;  4BXX E;  3S1Q E;  2WAQ H;  1TWH E;  5IP7 E;  3S14 E;  4A3C E;  3M3Y E;  3M4O E;  3GTO E;  4BY1 E;  2PMZ H;  4A3D E;  5FLM E;  3FKI E;  4A3G E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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