2UUYB

Structure of a tick tryptase inhibitor in complex with bovine trypsin
Total Genus 7
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
7
sequence length
52
structure length
52
Chain Sequence
CTVPIGWSEPVKGLCKARFTRYYCMGNCCKVYEGCYTGGYSRMGECARNCPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title A Tick Protein with a Modified Kunitz Fold Inhibits Human Tryptase.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords CATIONIC TRYPSIN
total genus 7
structure length 52
sequence length 52
ec nomenclature
pdb deposition date 2007-03-08
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 2uuyB01
4WXVC 4BD9B 1CBWD 3BTFI 3M7QB 3D65I 3LDJA 2FI4I 3P92E 2KAII 1YLCB 1D0DA 1QLQA 1BTIA 2FTMB 4Y0ZI 1BZ5A 2LFKA 5JB6A 2RA3C 3UOUB 2ZVXA 1T8LB 3TPII 1ZJDB 2TGPI 3CI7A 2J6DA 2DDIA 1BIKA 5JB4A 1P2NB 3U1JE 4BNRI 3P95E 1KIGI 4NTWB 1FY8I 1YLDB 1BRBI 1P2OB 1ZR0B 4BQDA 2LFLA 2ZJXA 1BRCI 4ISLB 3L3TE 1BTHP 1UUBA 2FI3I 4WWYC 3BTTI 2M01A 4NTYB 3FP6I 4ISNB 4TPII 3BTDI 1BF0A 1AALA 3AUBA 1BZXI 3TGJI 3T62D 8PTIA 1SHPA 1P2II 2KNTA 3BTQI 1P2QB 3FP7J 2FI5I 1DEMA 1JV8A 1NAGA 5JB7A 1T7CB 3WNYA 1KTHA 1EJMB 1Y62A 2PTCI 3BYBA 1JV9A 1MTND 2IJOI 2ODYE 3LDIA 5JB5A 2DDJA 3AUCA 3LDMA 1B0CA 1P2JI 1F7ZI 5PTIA 2JOTA 1DENA 3OTJI 1TAWB 1P2KI 2CA7A 2HEXA 1TFXC 1BUNB 1P2MB 1G6XA 1YKTB 4DG4C 1PITA 1UUAA 2UUXA 4NTXB 7PTIA 1FANA 1OA65 1CA0D 1K6UA 2UUYB 3OFWA 3AUDA 3BTEI 3L33E 2TPII 3FP8I 1F5RI 1BPIA 1YC0I 4U30W 1T8NB 3BTKI 1EAWB 1FAKI 2KCRA 4U32X 1BPTA 2M99A 2W8XA 1T8OB 1KNTA 1T8MB 1AAPA 3AUIA 6PTIA 5C67C 1OA55 1JC6A 1D0DB 3TGII 2R9PE 3UIRC 3TGKI 1ADZA 3BTWI 3BTMI 3AUEA 1TCPA 1LD5A 4ISOB 3AUGA 3AUHA 1CO7I 4Y0YI 1IRHA 4PTIA 1BHCA 1TAPA 4DTGK 1DTXA 3GYMI 3BTHI 3BTGI 1DTKA 4Y11I 1TOCR 1LD6A 2FTLI 1TPAI 9PTIA 4Y10I 1KUNA
chains in the Genus database with same CATH superfamily
4WXVC 4BD9B 1CBWD 3BTFI 3M7QB 3D65I 3LDJA 2FI4I 3P92E 2KAII 1YLCB 1D0DA 1QLQA 1BTIA 2FTMB 4Y0ZI 1BZ5A 2LFKA 5JB6A 2RA3C 3UOUB 2ZVXA 1T8LB 3TPII 1ZJDB 2TGPI 3CI7A 2J6DA 2DDIA 1BIKA 5JB4A 1P2NB 3U1JE 4BNRI 3P95E 1KIGI 4NTWB 1FY8I 1YLDB 1BRBI 1P2OB 1ZR0B 4BQDA 2LFLA 2ZJXA 1BRCI 4ISLB 3L3TE 1BTHP 1UUBA 2FI3I 4WWYC 3BTTI 2M01A 4NTYB 3FP6I 4ISNB 4TPII 3BTDI 1BF0A 1AALA 3AUBA 1BZXI 3TGJI 3T62D 8PTIA 1SHPA 1P2II 2KNTA 3BTQI 1P2QB 3FP7J 2FI5I 1DEMA 1JV8A 1NAGA 5JB7A 1T7CB 3WNYA 1KTHA 1EJMB 1Y62A 2PTCI 3BYBA 1JV9A 1MTND 2IJOI 2ODYE 3LDIA 5JB5A 2DDJA 3AUCA 3LDMA 1B0CA 1P2JI 1F7ZI 5PTIA 2JOTA 1DENA 3OTJI 1TAWB 1P2KI 2CA7A 2HEXA 1TFXC 1BUNB 1P2MB 1G6XA 1YKTB 4DG4C 1PITA 1UUAA 2UUXA 4NTXB 7PTIA 1FANA 1OA65 1CA0D 1K6UA 2UUYB 3OFWA 3AUDA 3BTEI 3L33E 2TPII 3FP8I 1F5RI 1BPIA 1YC0I 4U30W 1T8NB 3BTKI 1EAWB 1FAKI 2KCRA 4U32X 1BPTA 2M99A 2W8XA 1T8OB 1KNTA 1T8MB 1AAPA 3AUIA 6PTIA 5C67C 1OA55 1JC6A 1D0DB 3TGII 2R9PE 3UIRC 3TGKI 1ADZA 3BTWI 3BTMI 3AUEA 1TCPA 1LD5A 4ISOB 3AUGA 3AUHA 1CO7I 4Y0YI 1IRHA 4PTIA 1BHCA 1TAPA 4DTGK 1DTXA 3GYMI 3BTHI 3BTGI 1DTKA 4Y11I 1TOCR 1LD6A 2FTLI 1TPAI 9PTIA 4Y10I 1KUNA
chains in the Genus database with same CATH topology
4WXVC 4BD9B 1CBWD 3BTFI 3M7QB 3D65I 3LDJA 2FI4I 3P92E 2KAII 1YLCB 1D0DA 1QLQA 1BTIA 2FTMB 4Y0ZI 1BZ5A 2LFKA 5JB6A 2RA3C 3UOUB 2ZVXA 1T8LB 3TPII 1ZJDB 2TGPI 3CI7A 2J6DA 2DDIA 1BIKA 5JB4A 1P2NB 3U1JE 4BNRI 3P95E 1KIGI 4NTWB 1FY8I 1YLDB 1BRBI 1P2OB 1ZR0B 4BQDA 2LFLA 2ZJXA 1BRCI 4ISLB 3L3TE 1BTHP 1UUBA 2FI3I 4WWYC 3BTTI 2M01A 4NTYB 3FP6I 4ISNB 4TPII 3BTDI 1BF0A 1AALA 3AUBA 1BZXI 3TGJI 3T62D 8PTIA 1SHPA 1P2II 2KNTA 3BTQI 1P2QB 3FP7J 2FI5I 1DEMA 1JV8A 1NAGA 5JB7A 1T7CB 3WNYA 1KTHA 1EJMB 1Y62A 2PTCI 3BYBA 1JV9A 1MTND 2IJOI 2ODYE 3LDIA 5JB5A 2DDJA 3AUCA 3LDMA 1B0CA 1P2JI 1F7ZI 5PTIA 2JOTA 1DENA 3OTJI 1TAWB 1P2KI 2CA7A 2HEXA 1TFXC 1BUNB 1P2MB 1G6XA 1YKTB 4DG4C 1PITA 1UUAA 2UUXA 4NTXB 7PTIA 1FANA 1OA65 1CA0D 1K6UA 2UUYB 3OFWA 3AUDA 3BTEI 3L33E 2TPII 3FP8I 1F5RI 1BPIA 1YC0I 4U30W 1T8NB 3BTKI 1EAWB 1FAKI 2KCRA 4U32X 1BPTA 2M99A 2W8XA 1T8OB 1KNTA 1T8MB 1AAPA 3AUIA 6PTIA 5C67C 1OA55 1JC6A 1D0DB 3TGII 2R9PE 3UIRC 3TGKI 1ADZA 3BTWI 3BTMI 3AUEA 1TCPA 1LD5A 4ISOB 3AUGA 3AUHA 1CO7I 4Y0YI 1IRHA 4PTIA 1BHCA 1TAPA 4DTGK 1DTXA 3GYMI 3BTHI 3BTGI 1DTKA 4Y11I 1TOCR 1LD6A 2FTLI 1TPAI 9PTIA 4Y10I 1KUNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WXV C;  4BD9 B;  1CBW D;  3BTF I;  3M7Q B;  3D65 I;  3LDJ A;  2FI4 I;  3P92 E;  2KAI I;  1YLC B;  1D0D A;  1QLQ A;  1BTI A;  2FTM B;  4Y0Z I;  1BZ5 A;  2LFK A;  5JB6 A;  2RA3 C;  3UOU B;  2ZVX A;  1T8L B;  3TPI I;  1ZJD B;  2TGP I;  3CI7 A;  2J6D A;  2DDI A;  1BIK A;  5JB4 A;  1P2N B;  3U1J E;  4BNR I;  3P95 E;  1KIG I;  4NTW B;  1FY8 I;  1YLD B;  1BRB I;  1P2O B;  1ZR0 B;  4BQD A;  2LFL A;  2ZJX A;  1BRC I;  4ISL B;  3L3T E;  1BTH P;  1UUB A;  2FI3 I;  4WWY C;  3BTT I;  2M01 A;  4NTY B;  3FP6 I;  4ISN B;  4TPI I;  3BTD I;  1BF0 A;  1AAL A;  3AUB A;  1BZX I;  3TGJ I;  3T62 D;  8PTI A;  1SHP A;  1P2I I;  2KNT A;  3BTQ I;  1P2Q B;  3FP7 J;  2FI5 I;  1DEM A;  1JV8 A;  1NAG A;  5JB7 A;  1T7C B;  3WNY A;  1KTH A;  1EJM B;  1Y62 A;  2PTC I;  3BYB A;  1JV9 A;  1MTN D;  2IJO I;  2ODY E;  3LDI A;  5JB5 A;  2DDJ A;  3AUC A;  3LDM A;  1B0C A;  1P2J I;  1F7Z I;  5PTI A;  2JOT A;  1DEN A;  3OTJ I;  1TAW B;  1P2K I;  2CA7 A;  2HEX A;  1TFX C;  1BUN B;  1P2M B;  1G6X A;  1YKT B;  4DG4 C;  1PIT A;  1UUA A;  2UUX A;  4NTX B;  7PTI A;  1FAN A;  1OA6 5;  1CA0 D;  1K6U A;  2UUY B;  3OFW A;  3AUD A;  3BTE I;  3L33 E;  2TPI I;  3FP8 I;  1F5R I;  1BPI A;  1YC0 I;  4U30 W;  1T8N B;  3BTK I;  1EAW B;  1FAK I;  2KCR A;  4U32 X;  1BPT A;  2M99 A;  2W8X A;  1T8O B;  1KNT A;  1T8M B;  1AAP A;  3AUI A;  6PTI A;  5C67 C;  1OA5 5;  1JC6 A;  1D0D B;  3TGI I;  2R9P E;  3UIR C;  3TGK I;  1ADZ A;  3BTW I;  3BTM I;  3AUE A;  1TCP A;  1LD5 A;  4ISO B;  3AUG A;  3AUH A;  1CO7 I;  4Y0Y I;  1IRH A;  4PTI A;  1BHC A;  1TAP A;  4DTG K;  1DTX A;  3GYM I;  3BTH I;  3BTG I;  1DTK A;  4Y11 I;  1TOC R;  1LD6 A;  2FTL I;  1TPA I;  9PTI A;  4Y10 I;  1KUN A; 
#chains in the Genus database with same CATH topology
 4WXV C;  4BD9 B;  1CBW D;  3BTF I;  3M7Q B;  3D65 I;  3LDJ A;  2FI4 I;  3P92 E;  2KAI I;  1YLC B;  1D0D A;  1QLQ A;  1BTI A;  2FTM B;  4Y0Z I;  1BZ5 A;  2LFK A;  5JB6 A;  2RA3 C;  3UOU B;  2ZVX A;  1T8L B;  3TPI I;  1ZJD B;  2TGP I;  3CI7 A;  2J6D A;  2DDI A;  1BIK A;  5JB4 A;  1P2N B;  3U1J E;  4BNR I;  3P95 E;  1KIG I;  4NTW B;  1FY8 I;  1YLD B;  1BRB I;  1P2O B;  1ZR0 B;  4BQD A;  2LFL A;  2ZJX A;  1BRC I;  4ISL B;  3L3T E;  1BTH P;  1UUB A;  2FI3 I;  4WWY C;  3BTT I;  2M01 A;  4NTY B;  3FP6 I;  4ISN B;  4TPI I;  3BTD I;  1BF0 A;  1AAL A;  3AUB A;  1BZX I;  3TGJ I;  3T62 D;  8PTI A;  1SHP A;  1P2I I;  2KNT A;  3BTQ I;  1P2Q B;  3FP7 J;  2FI5 I;  1DEM A;  1JV8 A;  1NAG A;  5JB7 A;  1T7C B;  3WNY A;  1KTH A;  1EJM B;  1Y62 A;  2PTC I;  3BYB A;  1JV9 A;  1MTN D;  2IJO I;  2ODY E;  3LDI A;  5JB5 A;  2DDJ A;  3AUC A;  3LDM A;  1B0C A;  1P2J I;  1F7Z I;  5PTI A;  2JOT A;  1DEN A;  3OTJ I;  1TAW B;  1P2K I;  2CA7 A;  2HEX A;  1TFX C;  1BUN B;  1P2M B;  1G6X A;  1YKT B;  4DG4 C;  1PIT A;  1UUA A;  2UUX A;  4NTX B;  7PTI A;  1FAN A;  1OA6 5;  1CA0 D;  1K6U A;  2UUY B;  3OFW A;  3AUD A;  3BTE I;  3L33 E;  2TPI I;  3FP8 I;  1F5R I;  1BPI A;  1YC0 I;  4U30 W;  1T8N B;  3BTK I;  1EAW B;  1FAK I;  2KCR A;  4U32 X;  1BPT A;  2M99 A;  2W8X A;  1T8O B;  1KNT A;  1T8M B;  1AAP A;  3AUI A;  6PTI A;  5C67 C;  1OA5 5;  1JC6 A;  1D0D B;  3TGI I;  2R9P E;  3UIR C;  3TGK I;  1ADZ A;  3BTW I;  3BTM I;  3AUE A;  1TCP A;  1LD5 A;  4ISO B;  3AUG A;  3AUH A;  1CO7 I;  4Y0Y I;  1IRH A;  4PTI A;  1BHC A;  1TAP A;  4DTG K;  1DTX A;  3GYM I;  3BTH I;  3BTG I;  1DTK A;  4Y11 I;  1TOC R;  1LD6 A;  2FTL I;  1TPA I;  9PTI A;  4Y10 I;  1KUN A; 
#chains in the Genus database with same CATH homology
 4WXV C;  4BD9 B;  1CBW D;  3BTF I;  3M7Q B;  3D65 I;  3LDJ A;  2FI4 I;  3P92 E;  2KAI I;  1YLC B;  1D0D A;  1QLQ A;  1BTI A;  2FTM B;  4Y0Z I;  1BZ5 A;  2LFK A;  5JB6 A;  2RA3 C;  3UOU B;  2ZVX A;  1T8L B;  3TPI I;  1ZJD B;  2TGP I;  3CI7 A;  2J6D A;  2DDI A;  1BIK A;  5JB4 A;  1P2N B;  3U1J E;  4BNR I;  3P95 E;  1KIG I;  4NTW B;  1FY8 I;  1YLD B;  1BRB I;  1P2O B;  1ZR0 B;  4BQD A;  2LFL A;  2ZJX A;  1BRC I;  4ISL B;  3L3T E;  1BTH P;  1UUB A;  2FI3 I;  4WWY C;  3BTT I;  2M01 A;  4NTY B;  3FP6 I;  4ISN B;  4TPI I;  3BTD I;  1BF0 A;  1AAL A;  3AUB A;  1BZX I;  3TGJ I;  3T62 D;  8PTI A;  1SHP A;  1P2I I;  2KNT A;  3BTQ I;  1P2Q B;  3FP7 J;  2FI5 I;  1DEM A;  1JV8 A;  1NAG A;  5JB7 A;  1T7C B;  3WNY A;  1KTH A;  1EJM B;  1Y62 A;  2PTC I;  3BYB A;  1JV9 A;  1MTN D;  2IJO I;  2ODY E;  3LDI A;  5JB5 A;  2DDJ A;  3AUC A;  3LDM A;  1B0C A;  1P2J I;  1F7Z I;  5PTI A;  2JOT A;  1DEN A;  3OTJ I;  1TAW B;  1P2K I;  2CA7 A;  2HEX A;  1TFX C;  1BUN B;  1P2M B;  1G6X A;  1YKT B;  4DG4 C;  1PIT A;  1UUA A;  2UUX A;  4NTX B;  7PTI A;  1FAN A;  1OA6 5;  1CA0 D;  1K6U A;  2UUY B;  3OFW A;  3AUD A;  3BTE I;  3L33 E;  2TPI I;  3FP8 I;  1F5R I;  1BPI A;  1YC0 I;  4U30 W;  1T8N B;  3BTK I;  1EAW B;  1FAK I;  2KCR A;  4U32 X;  1BPT A;  2M99 A;  2W8X A;  1T8O B;  1KNT A;  1T8M B;  1AAP A;  3AUI A;  6PTI A;  5C67 C;  1OA5 5;  1JC6 A;  1D0D B;  3TGI I;  2R9P E;  3UIR C;  3TGK I;  1ADZ A;  3BTW I;  3BTM I;  3AUE A;  1TCP A;  1LD5 A;  4ISO B;  3AUG A;  3AUH A;  1CO7 I;  4Y0Y I;  1IRH A;  4PTI A;  1BHC A;  1TAP A;  4DTG K;  1DTX A;  3GYM I;  3BTH I;  3BTG I;  1DTK A;  4Y11 I;  1TOC R;  1LD6 A;  2FTL I;  1TPA I;  9PTI A;  4Y10 I;  1KUN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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