2YU9F

Rna polymerase ii elongation complex in 150 mm mg+2 with utp
Total Genus 20
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
20
sequence length
85
structure length
85
Chain Sequence
EKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
pubmed doi rcsb
molecule tags Transcription,transferase/dna-rna hybrid
molecule keywords 5'-R(*AP*UP*CP*GP*AP*GP*AP*GP*GP*A)-3'
total genus 20
structure length 85
sequence length 85
ec nomenclature
pdb deposition date 2007-04-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 2yu9F00
2Y0SI 4ZH4E 5M5WF 1I6HF 1TWHF 5IP7F 2NVYF 3CQZF 1Y1VF 4LJZE 5BYHE 5C3EF 4YFKE 5D4CE 2WAQK 4KN4E 3EQLE 5E18E 4A3MF 4XSZE 3GTLF 4C3HF 2PPBE 2E2JF 4BY7F 4C3IF 4G7HE 5D4DE 3HOUF 4A3JF 4A3FF 3H0GF 1ZYRE 2A69E 4KMUE 1Y1WF 1K83F 2O5JE 1TWFF 2B63F 3RZOF 4OINE 3S16F 3HOXF 2BE5E 2A6EE 4BY1F 3DXJE 4MEXE 1QKLA 4Q4ZE 2E2IF 2A6HE 4A3DF 2R93F 5IPLE 4G7ZE 1HQME 4LLGE 2A68E 4A3KF 5C4XF 3M3YF 4G7OE 3M4OF 3HOZF 4AYBK 3WODE 3GTGF 4MEYE 3I4NF 3K7AF 5IP9F 3I4MF 1TWCF 4A3LF 1SFOF 4C3JF 4Q5SE 4Y7NF 3HOWF 5TMFE 5IYDF 3S14F 3GTOF 2R92F 2CW0E 4A3CF 1IW7E 3S1RF 2R7ZF 1I3QF 4X6AF 4BBRF 2JA8F 3HKZK 4Y52F 4A93F 3FKIF 3S1QF 4MQ9E 2JA6F 3S1MF 3S2HF 3HOYF 2E2HF 1YNNK 2PMZK 1WCMF 5M3MF 4JK1E 3S17F 4BBSF 2WB1I 4GZYE 4C2MF 4A3BF 3GTQF 4A3EF 4YFXE 4BXXF 3H3VG 2JA5F 3GTPF 1SMYE 5M5YF 5C44F 3HOVF 4OIPE 3PO3F 5E17E 5FLMF 3S1NF 1YNJK 2O5IE 3RZDF 4A3IF 4KN7E 3S2DF 5TMCE 4XSXE 5M5XF 4YFNE 5IYCF 2JA7F 3GTKF 4A3GF 2NVXF 5M3FF 1TWAF 4OIOE 4XLPE 4OIRE 4LK0E 3S15F 2NVTF 5FJ8F 1I6VE 4OIQE 5C4JF 1I50F 5IYBF 4LK1E 4YG2E 2YU9F 3PO2F 3GTMF 2NVQF 4XLNE 2VUMF 3GTJF 1R9TF 5D4EE 1TWGF
chains in the Genus database with same CATH superfamily
1K83E 2Y0SI 4ZH4E 5M5WF 2B63E 3RZOE 1I6HF 3HOXE 1TWHF 4BY1E 5IP7F 3GTJE 2NVYF 3CQZF 1Y1VF 4LJZE 5BYHE 1TWGE 4YFKE 5C3EF 5D4CE 3H3VF 1EIKA 4A3DE 2WAQK 4KN4E 3EQLE 5E18E 4A3MF 4XSZE 3GTLF 4C3HF 2PPBE 2E2JF 4BY7F 4A3KE 4C3IF 4G7HE 5C3EE 5D4DE 3HOUF 3M3YE 5C4XE 4A3JF 4A3FF 3M4OE 3HOZE 3H0GF 1ZYRE 2A69E 3I4NE 4KMUE 1Y1WF 1K83F 3I4ME 5IP9E 1TWFF 1TWCE 2B63F 1SFOE 3RZOF 4C3JE 4OINE 3S16F 4A3LE 3HOXF 4AYBH 2BE5E 4Y7NE 2A6EE 4BY1F 3DXJE 5IYDE 4A3JE 4MEXE 3HOUE 3HOWE 1QKLA 4Q4ZE 2R92E 2Y0SH 4A3CE 2E2IF 1TWFE 2A6HE 2R7ZE 1I3QE 4A3DF 3S16E 4X6AE 2R93F 5IPLE 4G7ZE 1HQME 4LLGE 4A93E 2A68E 3FKIE 3S1QE 2JA6E 3S1ME 4A3KF 3S2HE 3HOYE 2E2HE 3M3YF 3HKZH 2E2IE 3M4OF 4G7OE 5C4XF 3HOZF 4AYBK 2R93E 3WODE 3GTGF 4MEYE 3I4NF 3K7AF 5IP9F 3I4MF 1TWCF 4A3LF 1SFOF 1WCME 4C3JF 5M3ME 4Q5SE 4Y7NF 4BBSE 3HOWF 5TMFE 5IYDF 4C2ME 2PMZH 3GTQE 4A3BE 3S14F 3GTOF 3GTGE 2R92F 2CW0E 4A3CF 1IW7E 3K7AE 3S1RF 2R7ZF 1I3QF 4X6AF 4BBRF 2JA8F 4BXXE 3HKZK 2JA5E 3GTPE 4Y52F 4A93F 3FKIF 5M5YE 5C44E 3S1QF 4MQ9E 2JA6F 3S14E 3S1MF 3S2HF 3GTOE 3PO3E 3HOYF 2E2HF 5FLME 3S1RE 3S1NE 1YNNK 4BBRE 2JA8E 2PMZK 4Y52E 4A3IE 1WCMF 2KRXA 5M3MF 4JK1E 3S17F 4BBSF 2WB1I 3S2DE 4GZYE 4C2MF 4A3BF 3GTQF 2O5JE 5M5XE 5IYCE 3GTKE 2JA7E 4A3GE 2NVXE 4A3EF 1TWAE 4YFXE 4BXXF 3S15E 3S17E 3H3VG 2NVTE 2JA5F 5FJ8E 3GTPF 1SMYE 5M5YF 5C44F 3HOVF 1DZFA 5C4JE 1I50E 4OIPE 5IYBE 3PO3F 4A3EE 5E17E 5FLMF 3S1NF 3PO2E 1YNJK 3GTME 2O5IE 2NVQE 3RZDF 4A3IF 2VUME 3HOVE 4KN7E 1R9TE 3S2DF 5TMCE 4XSXE 4QIWH 5M5XF 4YFNE 5M5WE 5IYCF 2JA7F 3GTKF 2NVXF 5M3FF 4A3GF 1I6HE 1TWAF 3RZDE 4XLPE 4OIOE 4OIRE 1TWHE 4LK0E 5IP7E 3S15F 2NVTF 2WB1H 2NVYE 5FJ8F 3CQZE 1Y1VE 1I6VE 4OIQE 5C4JF 1I50F 5IYBF 5M3FE 4LK1E 4YG2E 4A3ME 2YU9F 3GTLE 3PO2F 4C3HE 2E2JE 3GTMF 4QIWK 4BY7E 2NVQF 4XLNE 4C3IE 2WAQH 2VUMF 4A3FE 3GTJF 1R9TF 5D4EE 3H0GE 2YU9E 1Y1WE 1TWGF
chains in the Genus database with same CATH topology
2Y0SI 4ZH4E 5M5WF 1I6HF 1TWHF 5IP7F 2NVYF 3CQZF 1Y1VF 4LJZE 5BYHE 5C3EF 4YFKE 5D4CE 2WAQK 4KN4E 3EQLE 5E18E 4A3MF 4XSZE 3GTLF 4C3HF 2PPBE 2E2JF 4BY7F 4C3IF 4G7HE 5D4DE 3HOUF 4A3JF 4A3FF 3H0GF 1ZYRE 2A69E 4KMUE 1Y1WF 1K83F 2O5JE 1TWFF 2B63F 3RZOF 4OINE 3S16F 3HOXF 2BE5E 2A6EE 4BY1F 3DXJE 4MEXE 1QKLA 4Q4ZE 2E2IF 2A6HE 4A3DF 2R93F 5IPLE 4G7ZE 1HQME 4LLGE 2A68E 4A3KF 5C4XF 3M3YF 4G7OE 3M4OF 3HOZF 4AYBK 3WODE 3GTGF 4MEYE 3I4NF 3K7AF 5IP9F 3I4MF 1TWCF 4A3LF 1SFOF 4C3JF 4Q5SE 4Y7NF 3HOWF 5TMFE 5IYDF 3S14F 3GTOF 2R92F 2CW0E 4A3CF 1IW7E 3S1RF 2R7ZF 1I3QF 4X6AF 4BBRF 2JA8F 3HKZK 4Y52F 4A93F 3FKIF 3S1QF 4MQ9E 2JA6F 3S1MF 3S2HF 3HOYF 2E2HF 1YNNK 2PMZK 1WCMF 2KRXA 5M3MF 4JK1E 3S17F 4BBSF 2WB1I 4GZYE 4C2MF 4A3BF 3GTQF 4A3EF 4YFXE 4BXXF 3H3VG 2JA5F 3GTPF 1SMYE 5M5YF 5C44F 3HOVF 4OIPE 3PO3F 5E17E 5FLMF 3S1NF 1YNJK 2O5IE 3RZDF 4A3IF 4KN7E 3S2DF 5TMCE 4XSXE 5M5XF 4YFNE 5IYCF 2JA7F 3GTKF 4A3GF 2NVXF 5M3FF 1TWAF 4OIOE 4XLPE 4OIRE 4LK0E 3S15F 2NVTF 5FJ8F 1I6VE 4OIQE 5C4JF 1I50F 5IYBF 4LK1E 4YG2E 2YU9F 3PO2F 3GTMF 4QIWK 2NVQF 4XLNE 2VUMF 3GTJF 1R9TF 5D4EE 1TWGF
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Y0S I;  4ZH4 E;  5M5W F;  1I6H F;  1TWH F;  5IP7 F;  2NVY F;  3CQZ F;  1Y1V F;  4LJZ E;  5BYH E;  5C3E F;  4YFK E;  5D4C E;  2WAQ K;  4KN4 E;  3EQL E;  5E18 E;  4A3M F;  4XSZ E;  3GTL F;  4C3H F;  2PPB E;  2E2J F;  4BY7 F;  4C3I F;  4G7H E;  5D4D E;  3HOU F;  4A3J F;  4A3F F;  3H0G F;  1ZYR E;  2A69 E;  4KMU E;  1Y1W F;  1K83 F;  2O5J E;  1TWF F;  2B63 F;  3RZO F;  4OIN E;  3S16 F;  3HOX F;  2BE5 E;  2A6E E;  4BY1 F;  3DXJ E;  4MEX E;  1QKL A;  4Q4Z E;  2E2I F;  2A6H E;  4A3D F;  2R93 F;  5IPL E;  4G7Z E;  1HQM E;  4LLG E;  2A68 E;  4A3K F;  5C4X F;  3M3Y F;  4G7O E;  3M4O F;  3HOZ F;  4AYB K;  3WOD E;  3GTG F;  4MEY E;  3I4N F;  3K7A F;  5IP9 F;  3I4M F;  1TWC F;  4A3L F;  1SFO F;  4C3J F;  4Q5S E;  4Y7N F;  3HOW F;  5TMF E;  5IYD F;  3S14 F;  3GTO F;  2R92 F;  2CW0 E;  4A3C F;  1IW7 E;  3S1R F;  2R7Z F;  1I3Q F;  4X6A F;  4BBR F;  2JA8 F;  3HKZ K;  4Y52 F;  4A93 F;  3FKI F;  3S1Q F;  4MQ9 E;  2JA6 F;  3S1M F;  3S2H F;  3HOY F;  2E2H F;  1YNN K;  2PMZ K;  1WCM F;  5M3M F;  4JK1 E;  3S17 F;  4BBS F;  2WB1 I;  4GZY E;  4C2M F;  4A3B F;  3GTQ F;  4A3E F;  4YFX E;  4BXX F;  3H3V G;  2JA5 F;  3GTP F;  1SMY E;  5M5Y F;  5C44 F;  3HOV F;  4OIP E;  3PO3 F;  5E17 E;  5FLM F;  3S1N F;  1YNJ K;  2O5I E;  3RZD F;  4A3I F;  4KN7 E;  3S2D F;  5TMC E;  4XSX E;  5M5X F;  4YFN E;  5IYC F;  2JA7 F;  3GTK F;  4A3G F;  2NVX F;  5M3F F;  1TWA F;  4OIO E;  4XLP E;  4OIR E;  4LK0 E;  3S15 F;  2NVT F;  5FJ8 F;  1I6V E;  4OIQ E;  5C4J F;  1I50 F;  5IYB F;  4LK1 E;  4YG2 E;  2YU9 F;  3PO2 F;  3GTM F;  2NVQ F;  4XLN E;  2VUM F;  3GTJ F;  1R9T F;  5D4E E;  1TWG F; 
#chains in the Genus database with same CATH topology
 1K83 E;  2Y0S I;  4ZH4 E;  5M5W F;  2B63 E;  3RZO E;  1I6H F;  3HOX E;  1TWH F;  4BY1 E;  5IP7 F;  3GTJ E;  2NVY F;  3CQZ F;  1Y1V F;  4LJZ E;  5BYH E;  1TWG E;  4YFK E;  5C3E F;  5D4C E;  3H3V F;  1EIK A;  4A3D E;  2WAQ K;  4KN4 E;  3EQL E;  5E18 E;  4A3M F;  4XSZ E;  3GTL F;  4C3H F;  2PPB E;  2E2J F;  4BY7 F;  4A3K E;  4C3I F;  4G7H E;  5C3E E;  5D4D E;  3HOU F;  3M3Y E;  5C4X E;  4A3J F;  4A3F F;  3M4O E;  3HOZ E;  3H0G F;  1ZYR E;  2A69 E;  3I4N E;  4KMU E;  1Y1W F;  1K83 F;  3I4M E;  5IP9 E;  1TWF F;  1TWC E;  2B63 F;  1SFO E;  3RZO F;  4C3J E;  4OIN E;  3S16 F;  4A3L E;  3HOX F;  4AYB H;  2BE5 E;  4Y7N E;  2A6E E;  4BY1 F;  3DXJ E;  5IYD E;  4A3J E;  4MEX E;  3HOU E;  3HOW E;  1QKL A;  4Q4Z E;  2R92 E;  2Y0S H;  4A3C E;  2E2I F;  1TWF E;  2A6H E;  2R7Z E;  1I3Q E;  4A3D F;  3S16 E;  4X6A E;  2R93 F;  5IPL E;  4G7Z E;  1HQM E;  4LLG E;  4A93 E;  2A68 E;  3FKI E;  3S1Q E;  2JA6 E;  3S1M E;  4A3K F;  3S2H E;  3HOY E;  2E2H E;  3M3Y F;  3HKZ H;  2E2I E;  3M4O F;  4G7O E;  5C4X F;  3HOZ F;  4AYB K;  2R93 E;  3WOD E;  3GTG F;  4MEY E;  3I4N F;  3K7A F;  5IP9 F;  3I4M F;  1TWC F;  4A3L F;  1SFO F;  1WCM E;  4C3J F;  5M3M E;  4Q5S E;  4Y7N F;  4BBS E;  3HOW F;  5TMF E;  5IYD F;  4C2M E;  2PMZ H;  3GTQ E;  4A3B E;  3S14 F;  3GTO F;  3GTG E;  2R92 F;  2CW0 E;  4A3C F;  1IW7 E;  3K7A E;  3S1R F;  2R7Z F;  1I3Q F;  4X6A F;  4BBR F;  2JA8 F;  4BXX E;  3HKZ K;  2JA5 E;  3GTP E;  4Y52 F;  4A93 F;  3FKI F;  5M5Y E;  5C44 E;  3S1Q F;  4MQ9 E;  2JA6 F;  3S14 E;  3S1M F;  3S2H F;  3GTO E;  3PO3 E;  3HOY F;  2E2H F;  5FLM E;  3S1R E;  3S1N E;  1YNN K;  4BBR E;  2JA8 E;  2PMZ K;  4Y52 E;  4A3I E;  1WCM F;  2KRX A;  5M3M F;  4JK1 E;  3S17 F;  4BBS F;  2WB1 I;  3S2D E;  4GZY E;  4C2M F;  4A3B F;  3GTQ F;  2O5J E;  5M5X E;  5IYC E;  3GTK E;  2JA7 E;  4A3G E;  2NVX E;  4A3E F;  1TWA E;  4YFX E;  4BXX F;  3S15 E;  3S17 E;  3H3V G;  2NVT E;  2JA5 F;  5FJ8 E;  3GTP F;  1SMY E;  5M5Y F;  5C44 F;  3HOV F;  1DZF A;  5C4J E;  1I50 E;  4OIP E;  5IYB E;  3PO3 F;  4A3E E;  5E17 E;  5FLM F;  3S1N F;  3PO2 E;  1YNJ K;  3GTM E;  2O5I E;  2NVQ E;  3RZD F;  4A3I F;  2VUM E;  3HOV E;  4KN7 E;  1R9T E;  3S2D F;  5TMC E;  4XSX E;  4QIW H;  5M5X F;  4YFN E;  5M5W E;  5IYC F;  2JA7 F;  3GTK F;  2NVX F;  5M3F F;  4A3G F;  1I6H E;  1TWA F;  3RZD E;  4XLP E;  4OIO E;  4OIR E;  1TWH E;  4LK0 E;  5IP7 E;  3S15 F;  2NVT F;  2WB1 H;  2NVY E;  5FJ8 F;  3CQZ E;  1Y1V E;  1I6V E;  4OIQ E;  5C4J F;  1I50 F;  5IYB F;  5M3F E;  4LK1 E;  4YG2 E;  4A3M E;  2YU9 F;  3GTL E;  3PO2 F;  4C3H E;  2E2J E;  3GTM F;  4QIW K;  4BY7 E;  2NVQ F;  4XLN E;  4C3I E;  2WAQ H;  2VUM F;  4A3F E;  3GTJ F;  1R9T F;  5D4E E;  3H0G E;  2YU9 E;  1Y1W E;  1TWG F; 
#chains in the Genus database with same CATH homology
 2Y0S I;  4ZH4 E;  5M5W F;  1I6H F;  1TWH F;  5IP7 F;  2NVY F;  3CQZ F;  1Y1V F;  4LJZ E;  5BYH E;  5C3E F;  4YFK E;  5D4C E;  2WAQ K;  4KN4 E;  3EQL E;  5E18 E;  4A3M F;  4XSZ E;  3GTL F;  4C3H F;  2PPB E;  2E2J F;  4BY7 F;  4C3I F;  4G7H E;  5D4D E;  3HOU F;  4A3J F;  4A3F F;  3H0G F;  1ZYR E;  2A69 E;  4KMU E;  1Y1W F;  1K83 F;  2O5J E;  1TWF F;  2B63 F;  3RZO F;  4OIN E;  3S16 F;  3HOX F;  2BE5 E;  2A6E E;  4BY1 F;  3DXJ E;  4MEX E;  1QKL A;  4Q4Z E;  2E2I F;  2A6H E;  4A3D F;  2R93 F;  5IPL E;  4G7Z E;  1HQM E;  4LLG E;  2A68 E;  4A3K F;  5C4X F;  3M3Y F;  4G7O E;  3M4O F;  3HOZ F;  4AYB K;  3WOD E;  3GTG F;  4MEY E;  3I4N F;  3K7A F;  5IP9 F;  3I4M F;  1TWC F;  4A3L F;  1SFO F;  4C3J F;  4Q5S E;  4Y7N F;  3HOW F;  5TMF E;  5IYD F;  3S14 F;  3GTO F;  2R92 F;  2CW0 E;  4A3C F;  1IW7 E;  3S1R F;  2R7Z F;  1I3Q F;  4X6A F;  4BBR F;  2JA8 F;  3HKZ K;  4Y52 F;  4A93 F;  3FKI F;  3S1Q F;  4MQ9 E;  2JA6 F;  3S1M F;  3S2H F;  3HOY F;  2E2H F;  1YNN K;  2PMZ K;  1WCM F;  2KRX A;  5M3M F;  4JK1 E;  3S17 F;  4BBS F;  2WB1 I;  4GZY E;  4C2M F;  4A3B F;  3GTQ F;  4A3E F;  4YFX E;  4BXX F;  3H3V G;  2JA5 F;  3GTP F;  1SMY E;  5M5Y F;  5C44 F;  3HOV F;  4OIP E;  3PO3 F;  5E17 E;  5FLM F;  3S1N F;  1YNJ K;  2O5I E;  3RZD F;  4A3I F;  4KN7 E;  3S2D F;  5TMC E;  4XSX E;  5M5X F;  4YFN E;  5IYC F;  2JA7 F;  3GTK F;  4A3G F;  2NVX F;  5M3F F;  1TWA F;  4OIO E;  4XLP E;  4OIR E;  4LK0 E;  3S15 F;  2NVT F;  5FJ8 F;  1I6V E;  4OIQ E;  5C4J F;  1I50 F;  5IYB F;  4LK1 E;  4YG2 E;  2YU9 F;  3PO2 F;  3GTM F;  4QIW K;  2NVQ F;  4XLN E;  2VUM F;  3GTJ F;  1R9T F;  5D4E E;  1TWG F; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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