3AUEA

A simplified bpti variant with poly his amino acid tag (c5h) at the c-terminus
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
57
structure length
57
Chain Sequence
RPAFCLEPPYAGPGKARIIRYFYNAAAGAAQAFVYGGVRAKRNNFASAADALAACAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Effect of amino acid mutations on protein's solubility, function and structure characterized using short poly amino acid peptide tags
rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords Bovine pancreatic trypsin inhibitor
total genus 8
structure length 57
sequence length 57
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2011-02-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3aueA00
5JB7A 1FY8I 5JB6A 2DDJA 1T8OB 1BZ5A 3AUCA 1UUAA 3LDIA 3P95E 1BTIA 1G6XA 1DTKA 3P92E 1ADZA 3AUEA 5C67C 3BTGI 3AUBA 3BTTI 4U32X 3TPII 2ZVXA 1MTND 1JV9A 1YLCB 1TAWB 1QLQA 1ZR0B 1OA55 4NTXB 1KTHA 3UOUB 1P2MB 3TGII 2FTMB 4NTYB 2HEXA 1F7ZI 2R9PE 1FAKI 2TGPI 4BD9B 4DTGK 1DEMA 3T62D 3OFWA 2LFLA 1TFXC 2JOTA 4NTWB 1KNTA 3FP6I 4Y11I 1AALA 4WWYC 1P2KI 1YKTB 1BPTA 1DTXA 1EJMB 2UUXA 3BTQI 1BPIA 1K6UA 1P2QB 3FP8I 4ISLB 1BF0A 1TPAI 7PTIA 1IRHA 3BTDI 3AUHA 2PTCI 3BTEI 2KCRA 3UIRC 2FI3I 2ODYE 1P2II 1SHPA 2FI4I 1CA0D 1BZXI 1TOCR 3BTMI 1LD6A 1P2NB 3M7QB 2TPII 2CA7A 3LDJA 3BYBA 3TGJI 2ZJXA 1NAGA 1YC0I 2DDIA 1F5RI 1YLDB 1Y62A 1T8MB 1KIGI 1AAPA 4Y0YI 1BRCI 2KAII 1D0DA 2FI5I 2RA3C 1OA65 3FP7J 1CO7I 4WXVC 5PTIA 3L33E 1KUNA 2W8XA 1BIKA 4TPII 3GYMI 1TAPA 1BTHP 1FANA 1JC6A 1JV8A 3BTFI 4DG4C 1P2OB 1BHCA 1T8LB 8PTIA 4Y0ZI 1LD5A 4BQDA 3AUGA 3L3TE 4U30W 1ZJDB 1TCPA 1CBWD 2IJOI 1PITA 3D65I 4PTIA 2UUYB 1UUBA 4ISNB 1BRBI 2FTLI 2M01A 4BNRI 3BTWI 4ISOB 1EAWB 2KNTA 3AUDA 3OTJI 1P2JI 3U1JE 3LDMA 3TGKI 1D0DB 3BTKI 3AUIA 2J6DA 1BUNB 9PTIA 1T8NB 2M99A 3WNYA 2LFKA 4Y10I 5JB4A 1DENA 6PTIA 1T7CB 1B0CA 3CI7A 5JB5A 3BTHI
chains in the Genus database with same CATH superfamily
5JB7A 1FY8I 5JB6A 2DDJA 1T8OB 1BZ5A 3AUCA 1UUAA 3LDIA 3P95E 1BTIA 1G6XA 1DTKA 3P92E 1ADZA 3AUEA 5C67C 3BTGI 3AUBA 3BTTI 4U32X 3TPII 2ZVXA 1MTND 1JV9A 1YLCB 1TAWB 1QLQA 1ZR0B 1OA55 4NTXB 1KTHA 3UOUB 1P2MB 3TGII 2FTMB 4NTYB 2HEXA 1F7ZI 2R9PE 1FAKI 2TGPI 4BD9B 4DTGK 1DEMA 3T62D 3OFWA 2LFLA 1TFXC 2JOTA 4NTWB 1KNTA 3FP6I 4Y11I 1AALA 4WWYC 1P2KI 1YKTB 1BPTA 1DTXA 1EJMB 2UUXA 3BTQI 1BPIA 1K6UA 1P2QB 3FP8I 4ISLB 1BF0A 1TPAI 7PTIA 1IRHA 3BTDI 3AUHA 2PTCI 3BTEI 2KCRA 3UIRC 2FI3I 2ODYE 1P2II 1SHPA 2FI4I 1CA0D 1BZXI 1TOCR 3BTMI 1LD6A 1P2NB 3M7QB 2TPII 2CA7A 3LDJA 3BYBA 3TGJI 2ZJXA 1NAGA 1YC0I 2DDIA 1F5RI 1YLDB 1Y62A 1T8MB 1KIGI 1AAPA 4Y0YI 1BRCI 2KAII 1D0DA 2FI5I 2RA3C 1OA65 3FP7J 1CO7I 4WXVC 5PTIA 3L33E 1KUNA 2W8XA 1BIKA 4TPII 3GYMI 1TAPA 1BTHP 1FANA 1JC6A 1JV8A 3BTFI 4DG4C 1P2OB 1BHCA 1T8LB 8PTIA 4Y0ZI 1LD5A 4BQDA 3AUGA 3L3TE 4U30W 1ZJDB 1TCPA 1CBWD 2IJOI 1PITA 3D65I 4PTIA 2UUYB 1UUBA 4ISNB 1BRBI 2FTLI 2M01A 4BNRI 3BTWI 4ISOB 1EAWB 2KNTA 3AUDA 3OTJI 1P2JI 3U1JE 3LDMA 3TGKI 1D0DB 3BTKI 3AUIA 2J6DA 1BUNB 9PTIA 1T8NB 2M99A 3WNYA 2LFKA 4Y10I 5JB4A 1DENA 6PTIA 1T7CB 1B0CA 3CI7A 5JB5A 3BTHI
chains in the Genus database with same CATH topology
5JB7A 1FY8I 5JB6A 2DDJA 1T8OB 1BZ5A 3AUCA 1UUAA 3LDIA 3P95E 1BTIA 1G6XA 1DTKA 3P92E 1ADZA 3AUEA 5C67C 3BTGI 3AUBA 3BTTI 4U32X 3TPII 2ZVXA 1MTND 1JV9A 1YLCB 1TAWB 1QLQA 1ZR0B 1OA55 4NTXB 1KTHA 3UOUB 1P2MB 3TGII 2FTMB 4NTYB 2HEXA 1F7ZI 2R9PE 1FAKI 2TGPI 4BD9B 4DTGK 1DEMA 3T62D 3OFWA 2LFLA 1TFXC 2JOTA 4NTWB 1KNTA 3FP6I 4Y11I 1AALA 4WWYC 1P2KI 1YKTB 1BPTA 1DTXA 1EJMB 2UUXA 3BTQI 1BPIA 1K6UA 1P2QB 3FP8I 4ISLB 1BF0A 1TPAI 7PTIA 1IRHA 3BTDI 3AUHA 2PTCI 3BTEI 2KCRA 3UIRC 2FI3I 2ODYE 1P2II 1SHPA 2FI4I 1CA0D 1BZXI 1TOCR 3BTMI 1LD6A 1P2NB 3M7QB 2TPII 2CA7A 3LDJA 3BYBA 3TGJI 2ZJXA 1NAGA 1YC0I 2DDIA 1F5RI 1YLDB 1Y62A 1T8MB 1KIGI 1AAPA 4Y0YI 1BRCI 2KAII 1D0DA 2FI5I 2RA3C 1OA65 3FP7J 1CO7I 4WXVC 5PTIA 3L33E 1KUNA 2W8XA 1BIKA 4TPII 3GYMI 1TAPA 1BTHP 1FANA 1JC6A 1JV8A 3BTFI 4DG4C 1P2OB 1BHCA 1T8LB 8PTIA 4Y0ZI 1LD5A 4BQDA 3AUGA 3L3TE 4U30W 1ZJDB 1TCPA 1CBWD 2IJOI 1PITA 3D65I 4PTIA 2UUYB 1UUBA 4ISNB 1BRBI 2FTLI 2M01A 4BNRI 3BTWI 4ISOB 1EAWB 2KNTA 3AUDA 3OTJI 1P2JI 3U1JE 3LDMA 3TGKI 1D0DB 3BTKI 3AUIA 2J6DA 1BUNB 9PTIA 1T8NB 2M99A 3WNYA 2LFKA 4Y10I 5JB4A 1DENA 6PTIA 1T7CB 1B0CA 3CI7A 5JB5A 3BTHI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JB7 A;  1FY8 I;  5JB6 A;  2DDJ A;  1T8O B;  1BZ5 A;  3AUC A;  1UUA A;  3LDI A;  3P95 E;  1BTI A;  1G6X A;  1DTK A;  3P92 E;  1ADZ A;  3AUE A;  5C67 C;  3BTG I;  3AUB A;  3BTT I;  4U32 X;  3TPI I;  2ZVX A;  1MTN D;  1JV9 A;  1YLC B;  1TAW B;  1QLQ A;  1ZR0 B;  1OA5 5;  4NTX B;  1KTH A;  3UOU B;  1P2M B;  3TGI I;  2FTM B;  4NTY B;  2HEX A;  1F7Z I;  2R9P E;  1FAK I;  2TGP I;  4BD9 B;  4DTG K;  1DEM A;  3T62 D;  3OFW A;  2LFL A;  1TFX C;  2JOT A;  4NTW B;  1KNT A;  3FP6 I;  4Y11 I;  1AAL A;  4WWY C;  1P2K I;  1YKT B;  1BPT A;  1DTX A;  1EJM B;  2UUX A;  3BTQ I;  1BPI A;  1K6U A;  1P2Q B;  3FP8 I;  4ISL B;  1BF0 A;  1TPA I;  7PTI A;  1IRH A;  3BTD I;  3AUH A;  2PTC I;  3BTE I;  2KCR A;  3UIR C;  2FI3 I;  2ODY E;  1P2I I;  1SHP A;  2FI4 I;  1CA0 D;  1BZX I;  1TOC R;  3BTM I;  1LD6 A;  1P2N B;  3M7Q B;  2TPI I;  2CA7 A;  3LDJ A;  3BYB A;  3TGJ I;  2ZJX A;  1NAG A;  1YC0 I;  2DDI A;  1F5R I;  1YLD B;  1Y62 A;  1T8M B;  1KIG I;  1AAP A;  4Y0Y I;  1BRC I;  2KAI I;  1D0D A;  2FI5 I;  2RA3 C;  1OA6 5;  3FP7 J;  1CO7 I;  4WXV C;  5PTI A;  3L33 E;  1KUN A;  2W8X A;  1BIK A;  4TPI I;  3GYM I;  1TAP A;  1BTH P;  1FAN A;  1JC6 A;  1JV8 A;  3BTF I;  4DG4 C;  1P2O B;  1BHC A;  1T8L B;  8PTI A;  4Y0Z I;  1LD5 A;  4BQD A;  3AUG A;  3L3T E;  4U30 W;  1ZJD B;  1TCP A;  1CBW D;  2IJO I;  1PIT A;  3D65 I;  4PTI A;  2UUY B;  1UUB A;  4ISN B;  1BRB I;  2FTL I;  2M01 A;  4BNR I;  3BTW I;  4ISO B;  1EAW B;  2KNT A;  3AUD A;  3OTJ I;  1P2J I;  3U1J E;  3LDM A;  3TGK I;  1D0D B;  3BTK I;  3AUI A;  2J6D A;  1BUN B;  9PTI A;  1T8N B;  2M99 A;  3WNY A;  2LFK A;  4Y10 I;  5JB4 A;  1DEN A;  6PTI A;  1T7C B;  1B0C A;  3CI7 A;  5JB5 A;  3BTH I; 
#chains in the Genus database with same CATH topology
 5JB7 A;  1FY8 I;  5JB6 A;  2DDJ A;  1T8O B;  1BZ5 A;  3AUC A;  1UUA A;  3LDI A;  3P95 E;  1BTI A;  1G6X A;  1DTK A;  3P92 E;  1ADZ A;  3AUE A;  5C67 C;  3BTG I;  3AUB A;  3BTT I;  4U32 X;  3TPI I;  2ZVX A;  1MTN D;  1JV9 A;  1YLC B;  1TAW B;  1QLQ A;  1ZR0 B;  1OA5 5;  4NTX B;  1KTH A;  3UOU B;  1P2M B;  3TGI I;  2FTM B;  4NTY B;  2HEX A;  1F7Z I;  2R9P E;  1FAK I;  2TGP I;  4BD9 B;  4DTG K;  1DEM A;  3T62 D;  3OFW A;  2LFL A;  1TFX C;  2JOT A;  4NTW B;  1KNT A;  3FP6 I;  4Y11 I;  1AAL A;  4WWY C;  1P2K I;  1YKT B;  1BPT A;  1DTX A;  1EJM B;  2UUX A;  3BTQ I;  1BPI A;  1K6U A;  1P2Q B;  3FP8 I;  4ISL B;  1BF0 A;  1TPA I;  7PTI A;  1IRH A;  3BTD I;  3AUH A;  2PTC I;  3BTE I;  2KCR A;  3UIR C;  2FI3 I;  2ODY E;  1P2I I;  1SHP A;  2FI4 I;  1CA0 D;  1BZX I;  1TOC R;  3BTM I;  1LD6 A;  1P2N B;  3M7Q B;  2TPI I;  2CA7 A;  3LDJ A;  3BYB A;  3TGJ I;  2ZJX A;  1NAG A;  1YC0 I;  2DDI A;  1F5R I;  1YLD B;  1Y62 A;  1T8M B;  1KIG I;  1AAP A;  4Y0Y I;  1BRC I;  2KAI I;  1D0D A;  2FI5 I;  2RA3 C;  1OA6 5;  3FP7 J;  1CO7 I;  4WXV C;  5PTI A;  3L33 E;  1KUN A;  2W8X A;  1BIK A;  4TPI I;  3GYM I;  1TAP A;  1BTH P;  1FAN A;  1JC6 A;  1JV8 A;  3BTF I;  4DG4 C;  1P2O B;  1BHC A;  1T8L B;  8PTI A;  4Y0Z I;  1LD5 A;  4BQD A;  3AUG A;  3L3T E;  4U30 W;  1ZJD B;  1TCP A;  1CBW D;  2IJO I;  1PIT A;  3D65 I;  4PTI A;  2UUY B;  1UUB A;  4ISN B;  1BRB I;  2FTL I;  2M01 A;  4BNR I;  3BTW I;  4ISO B;  1EAW B;  2KNT A;  3AUD A;  3OTJ I;  1P2J I;  3U1J E;  3LDM A;  3TGK I;  1D0D B;  3BTK I;  3AUI A;  2J6D A;  1BUN B;  9PTI A;  1T8N B;  2M99 A;  3WNY A;  2LFK A;  4Y10 I;  5JB4 A;  1DEN A;  6PTI A;  1T7C B;  1B0C A;  3CI7 A;  5JB5 A;  3BTH I; 
#chains in the Genus database with same CATH homology
 5JB7 A;  1FY8 I;  5JB6 A;  2DDJ A;  1T8O B;  1BZ5 A;  3AUC A;  1UUA A;  3LDI A;  3P95 E;  1BTI A;  1G6X A;  1DTK A;  3P92 E;  1ADZ A;  3AUE A;  5C67 C;  3BTG I;  3AUB A;  3BTT I;  4U32 X;  3TPI I;  2ZVX A;  1MTN D;  1JV9 A;  1YLC B;  1TAW B;  1QLQ A;  1ZR0 B;  1OA5 5;  4NTX B;  1KTH A;  3UOU B;  1P2M B;  3TGI I;  2FTM B;  4NTY B;  2HEX A;  1F7Z I;  2R9P E;  1FAK I;  2TGP I;  4BD9 B;  4DTG K;  1DEM A;  3T62 D;  3OFW A;  2LFL A;  1TFX C;  2JOT A;  4NTW B;  1KNT A;  3FP6 I;  4Y11 I;  1AAL A;  4WWY C;  1P2K I;  1YKT B;  1BPT A;  1DTX A;  1EJM B;  2UUX A;  3BTQ I;  1BPI A;  1K6U A;  1P2Q B;  3FP8 I;  4ISL B;  1BF0 A;  1TPA I;  7PTI A;  1IRH A;  3BTD I;  3AUH A;  2PTC I;  3BTE I;  2KCR A;  3UIR C;  2FI3 I;  2ODY E;  1P2I I;  1SHP A;  2FI4 I;  1CA0 D;  1BZX I;  1TOC R;  3BTM I;  1LD6 A;  1P2N B;  3M7Q B;  2TPI I;  2CA7 A;  3LDJ A;  3BYB A;  3TGJ I;  2ZJX A;  1NAG A;  1YC0 I;  2DDI A;  1F5R I;  1YLD B;  1Y62 A;  1T8M B;  1KIG I;  1AAP A;  4Y0Y I;  1BRC I;  2KAI I;  1D0D A;  2FI5 I;  2RA3 C;  1OA6 5;  3FP7 J;  1CO7 I;  4WXV C;  5PTI A;  3L33 E;  1KUN A;  2W8X A;  1BIK A;  4TPI I;  3GYM I;  1TAP A;  1BTH P;  1FAN A;  1JC6 A;  1JV8 A;  3BTF I;  4DG4 C;  1P2O B;  1BHC A;  1T8L B;  8PTI A;  4Y0Z I;  1LD5 A;  4BQD A;  3AUG A;  3L3T E;  4U30 W;  1ZJD B;  1TCP A;  1CBW D;  2IJO I;  1PIT A;  3D65 I;  4PTI A;  2UUY B;  1UUB A;  4ISN B;  1BRB I;  2FTL I;  2M01 A;  4BNR I;  3BTW I;  4ISO B;  1EAW B;  2KNT A;  3AUD A;  3OTJ I;  1P2J I;  3U1J E;  3LDM A;  3TGK I;  1D0D B;  3BTK I;  3AUI A;  2J6D A;  1BUN B;  9PTI A;  1T8N B;  2M99 A;  3WNY A;  2LFK A;  4Y10 I;  5JB4 A;  1DEN A;  6PTI A;  1T7C B;  1B0C A;  3CI7 A;  5JB5 A;  3BTH I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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