3CI7A

Crystal structure of a simplified bpti containing 20 alanines
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
58
structure length
58
Chain Sequence
RPAFCLEPPYAGPGKARIIRYFYNAAAGAAQAFVYGGARAKRNNFASAADALAACAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines
pubmed doi rcsb
molecule tags Hydrolase inhibitor
molecule keywords bovine pancreatic trypsin inhibitor
total genus 8
structure length 58
sequence length 58
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-03-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3ci7A00
1CBWD 4BQDA 1EAWB 1KNTA 1DENA 1P2KI 3FP8I 5PTIA 5JB4A 1DTXA 1T8OB 2TPII 3L3TE 1BUNB 3BTMI 1OA65 2HEXA 2KCRA 2LFKA 4Y11I 1BTIA 2UUXA 3AUCA 1ADZA 4TPII 4Y10I 4WXVC 4Y0YI 1P2NB 2FI4I 4DG4C 1B0CA 4Y0ZI 4WWYC 3LDJA 1KUNA 2FTMB 1OA55 1T8LB 1CO7I 3TGII 1Y62A 1FAKI 3AUGA 2ZJXA 3UIRC 1AALA 1MTND 1CA0D 4U30W 3WNYA 1BRBI 3FP6I 1TAWB 1IRHA 1UUBA 1D0DA 5C67C 4ISOB 2ODYE 3FP7J 5JB5A 3TGKI 2M01A 1YC0I 3AUDA 3OFWA 3U1JE 1DTKA 1UUAA 3BTDI 1TFXC 1KTHA 1ZR0B 2CA7A 1BIKA 1YKTB 3BTEI 7PTIA 1FY8I 1BHCA 1P2OB 3BTHI 4BD9B 1TPAI 1BRCI 2ZVXA 4NTWB 3BTWI 5JB6A 1KIGI 4U32X 1P2QB 3L33E 3LDIA 2FTLI 3D65I 2TGPI 2R9PE 3AUIA 3P92E 1YLCB 1JV9A 1TAPA 1T8NB 2FI5I 3GYMI 4PTIA 2DDJA 3BTFI 2W8XA 4DTGK 4ISLB 1YLDB 1PITA 3AUHA 1QLQA 1BZ5A 3BTKI 3TGJI 2KAII 1BTHP 1BPIA 1JC6A 6PTIA 4NTXB 2KNTA 3BYBA 2UUYB 2PTCI 1LD5A 1T8MB 3M7QB 3CI7A 1AAPA 1D0DB 1LD6A 2FI3I 1P2JI 1T7CB 3T62D 2DDIA 3TPII 1BPTA 1P2II 2RA3C 1G6XA 1BZXI 4NTYB 1SHPA 3AUBA 1EJMB 1F5RI 1FANA 1JV8A 1NAGA 3UOUB 2J6DA 3LDMA 1P2MB 3AUEA 3OTJI 3P95E 1TCPA 2IJOI 2JOTA 4ISNB 2M99A 2LFLA 1K6UA 1TOCR 4BNRI 1F7ZI 3BTTI 1ZJDB 3BTQI 3BTGI 9PTIA 5JB7A 1DEMA 1BF0A 8PTIA
chains in the Genus database with same CATH superfamily
1CBWD 4BQDA 1EAWB 1KNTA 1DENA 1P2KI 3FP8I 5PTIA 5JB4A 1DTXA 1T8OB 2TPII 3L3TE 1BUNB 3BTMI 1OA65 2HEXA 2KCRA 2LFKA 4Y11I 1BTIA 2UUXA 3AUCA 1ADZA 4TPII 4Y10I 4WXVC 4Y0YI 1P2NB 2FI4I 4DG4C 1B0CA 4Y0ZI 4WWYC 3LDJA 1KUNA 2FTMB 1OA55 1T8LB 1CO7I 3TGII 1Y62A 1FAKI 3AUGA 2ZJXA 3UIRC 1AALA 1MTND 1CA0D 4U30W 3WNYA 1BRBI 3FP6I 1TAWB 1IRHA 1UUBA 1D0DA 5C67C 4ISOB 2ODYE 3FP7J 5JB5A 3TGKI 2M01A 1YC0I 3AUDA 3OFWA 3U1JE 1DTKA 1UUAA 3BTDI 1TFXC 1KTHA 1ZR0B 2CA7A 1BIKA 1YKTB 3BTEI 7PTIA 1FY8I 1BHCA 1P2OB 3BTHI 4BD9B 1TPAI 1BRCI 2ZVXA 4NTWB 3BTWI 5JB6A 1KIGI 4U32X 1P2QB 3L33E 3LDIA 2FTLI 3D65I 2TGPI 2R9PE 3AUIA 3P92E 1YLCB 1JV9A 1TAPA 1T8NB 2FI5I 3GYMI 4PTIA 2DDJA 3BTFI 2W8XA 4DTGK 4ISLB 1YLDB 1PITA 3AUHA 1QLQA 1BZ5A 3BTKI 3TGJI 2KAII 1BTHP 1BPIA 1JC6A 6PTIA 4NTXB 2KNTA 3BYBA 2UUYB 2PTCI 1LD5A 1T8MB 3M7QB 3CI7A 1AAPA 1D0DB 1LD6A 2FI3I 1P2JI 1T7CB 3T62D 2DDIA 3TPII 1BPTA 1P2II 2RA3C 1G6XA 1BZXI 4NTYB 1SHPA 3AUBA 1EJMB 1F5RI 1FANA 1JV8A 1NAGA 3UOUB 2J6DA 3LDMA 1P2MB 3AUEA 3OTJI 3P95E 1TCPA 2IJOI 2JOTA 4ISNB 2M99A 2LFLA 1K6UA 1TOCR 4BNRI 1F7ZI 3BTTI 1ZJDB 3BTQI 3BTGI 9PTIA 5JB7A 1DEMA 1BF0A 8PTIA
chains in the Genus database with same CATH topology
1CBWD 4BQDA 1EAWB 1KNTA 1DENA 1P2KI 3FP8I 5PTIA 5JB4A 1DTXA 1T8OB 2TPII 3L3TE 1BUNB 3BTMI 1OA65 2HEXA 2KCRA 2LFKA 4Y11I 1BTIA 2UUXA 3AUCA 1ADZA 4TPII 4Y10I 4WXVC 4Y0YI 1P2NB 2FI4I 4DG4C 1B0CA 4Y0ZI 4WWYC 3LDJA 1KUNA 2FTMB 1OA55 1T8LB 1CO7I 3TGII 1Y62A 1FAKI 3AUGA 2ZJXA 3UIRC 1AALA 1MTND 1CA0D 4U30W 3WNYA 1BRBI 3FP6I 1TAWB 1IRHA 1UUBA 1D0DA 5C67C 4ISOB 2ODYE 3FP7J 5JB5A 3TGKI 2M01A 1YC0I 3AUDA 3OFWA 3U1JE 1DTKA 1UUAA 3BTDI 1TFXC 1KTHA 1ZR0B 2CA7A 1BIKA 1YKTB 3BTEI 7PTIA 1FY8I 1BHCA 1P2OB 3BTHI 4BD9B 1TPAI 1BRCI 2ZVXA 4NTWB 3BTWI 5JB6A 1KIGI 4U32X 1P2QB 3L33E 3LDIA 2FTLI 3D65I 2TGPI 2R9PE 3AUIA 3P92E 1YLCB 1JV9A 1TAPA 1T8NB 2FI5I 3GYMI 4PTIA 2DDJA 3BTFI 2W8XA 4DTGK 4ISLB 1YLDB 1PITA 3AUHA 1QLQA 1BZ5A 3BTKI 3TGJI 2KAII 1BTHP 1BPIA 1JC6A 6PTIA 4NTXB 2KNTA 3BYBA 2UUYB 2PTCI 1LD5A 1T8MB 3M7QB 3CI7A 1AAPA 1D0DB 1LD6A 2FI3I 1P2JI 1T7CB 3T62D 2DDIA 3TPII 1BPTA 1P2II 2RA3C 1G6XA 1BZXI 4NTYB 1SHPA 3AUBA 1EJMB 1F5RI 1FANA 1JV8A 1NAGA 3UOUB 2J6DA 3LDMA 1P2MB 3AUEA 3OTJI 3P95E 1TCPA 2IJOI 2JOTA 4ISNB 2M99A 2LFLA 1K6UA 1TOCR 4BNRI 1F7ZI 3BTTI 1ZJDB 3BTQI 3BTGI 9PTIA 5JB7A 1DEMA 1BF0A 8PTIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1CBW D;  4BQD A;  1EAW B;  1KNT A;  1DEN A;  1P2K I;  3FP8 I;  5PTI A;  5JB4 A;  1DTX A;  1T8O B;  2TPI I;  3L3T E;  1BUN B;  3BTM I;  1OA6 5;  2HEX A;  2KCR A;  2LFK A;  4Y11 I;  1BTI A;  2UUX A;  3AUC A;  1ADZ A;  4TPI I;  4Y10 I;  4WXV C;  4Y0Y I;  1P2N B;  2FI4 I;  4DG4 C;  1B0C A;  4Y0Z I;  4WWY C;  3LDJ A;  1KUN A;  2FTM B;  1OA5 5;  1T8L B;  1CO7 I;  3TGI I;  1Y62 A;  1FAK I;  3AUG A;  2ZJX A;  3UIR C;  1AAL A;  1MTN D;  1CA0 D;  4U30 W;  3WNY A;  1BRB I;  3FP6 I;  1TAW B;  1IRH A;  1UUB A;  1D0D A;  5C67 C;  4ISO B;  2ODY E;  3FP7 J;  5JB5 A;  3TGK I;  2M01 A;  1YC0 I;  3AUD A;  3OFW A;  3U1J E;  1DTK A;  1UUA A;  3BTD I;  1TFX C;  1KTH A;  1ZR0 B;  2CA7 A;  1BIK A;  1YKT B;  3BTE I;  7PTI A;  1FY8 I;  1BHC A;  1P2O B;  3BTH I;  4BD9 B;  1TPA I;  1BRC I;  2ZVX A;  4NTW B;  3BTW I;  5JB6 A;  1KIG I;  4U32 X;  1P2Q B;  3L33 E;  3LDI A;  2FTL I;  3D65 I;  2TGP I;  2R9P E;  3AUI A;  3P92 E;  1YLC B;  1JV9 A;  1TAP A;  1T8N B;  2FI5 I;  3GYM I;  4PTI A;  2DDJ A;  3BTF I;  2W8X A;  4DTG K;  4ISL B;  1YLD B;  1PIT A;  3AUH A;  1QLQ A;  1BZ5 A;  3BTK I;  3TGJ I;  2KAI I;  1BTH P;  1BPI A;  1JC6 A;  6PTI A;  4NTX B;  2KNT A;  3BYB A;  2UUY B;  2PTC I;  1LD5 A;  1T8M B;  3M7Q B;  3CI7 A;  1AAP A;  1D0D B;  1LD6 A;  2FI3 I;  1P2J I;  1T7C B;  3T62 D;  2DDI A;  3TPI I;  1BPT A;  1P2I I;  2RA3 C;  1G6X A;  1BZX I;  4NTY B;  1SHP A;  3AUB A;  1EJM B;  1F5R I;  1FAN A;  1JV8 A;  1NAG A;  3UOU B;  2J6D A;  3LDM A;  1P2M B;  3AUE A;  3OTJ I;  3P95 E;  1TCP A;  2IJO I;  2JOT A;  4ISN B;  2M99 A;  2LFL A;  1K6U A;  1TOC R;  4BNR I;  1F7Z I;  3BTT I;  1ZJD B;  3BTQ I;  3BTG I;  9PTI A;  5JB7 A;  1DEM A;  1BF0 A;  8PTI A; 
#chains in the Genus database with same CATH topology
 1CBW D;  4BQD A;  1EAW B;  1KNT A;  1DEN A;  1P2K I;  3FP8 I;  5PTI A;  5JB4 A;  1DTX A;  1T8O B;  2TPI I;  3L3T E;  1BUN B;  3BTM I;  1OA6 5;  2HEX A;  2KCR A;  2LFK A;  4Y11 I;  1BTI A;  2UUX A;  3AUC A;  1ADZ A;  4TPI I;  4Y10 I;  4WXV C;  4Y0Y I;  1P2N B;  2FI4 I;  4DG4 C;  1B0C A;  4Y0Z I;  4WWY C;  3LDJ A;  1KUN A;  2FTM B;  1OA5 5;  1T8L B;  1CO7 I;  3TGI I;  1Y62 A;  1FAK I;  3AUG A;  2ZJX A;  3UIR C;  1AAL A;  1MTN D;  1CA0 D;  4U30 W;  3WNY A;  1BRB I;  3FP6 I;  1TAW B;  1IRH A;  1UUB A;  1D0D A;  5C67 C;  4ISO B;  2ODY E;  3FP7 J;  5JB5 A;  3TGK I;  2M01 A;  1YC0 I;  3AUD A;  3OFW A;  3U1J E;  1DTK A;  1UUA A;  3BTD I;  1TFX C;  1KTH A;  1ZR0 B;  2CA7 A;  1BIK A;  1YKT B;  3BTE I;  7PTI A;  1FY8 I;  1BHC A;  1P2O B;  3BTH I;  4BD9 B;  1TPA I;  1BRC I;  2ZVX A;  4NTW B;  3BTW I;  5JB6 A;  1KIG I;  4U32 X;  1P2Q B;  3L33 E;  3LDI A;  2FTL I;  3D65 I;  2TGP I;  2R9P E;  3AUI A;  3P92 E;  1YLC B;  1JV9 A;  1TAP A;  1T8N B;  2FI5 I;  3GYM I;  4PTI A;  2DDJ A;  3BTF I;  2W8X A;  4DTG K;  4ISL B;  1YLD B;  1PIT A;  3AUH A;  1QLQ A;  1BZ5 A;  3BTK I;  3TGJ I;  2KAI I;  1BTH P;  1BPI A;  1JC6 A;  6PTI A;  4NTX B;  2KNT A;  3BYB A;  2UUY B;  2PTC I;  1LD5 A;  1T8M B;  3M7Q B;  3CI7 A;  1AAP A;  1D0D B;  1LD6 A;  2FI3 I;  1P2J I;  1T7C B;  3T62 D;  2DDI A;  3TPI I;  1BPT A;  1P2I I;  2RA3 C;  1G6X A;  1BZX I;  4NTY B;  1SHP A;  3AUB A;  1EJM B;  1F5R I;  1FAN A;  1JV8 A;  1NAG A;  3UOU B;  2J6D A;  3LDM A;  1P2M B;  3AUE A;  3OTJ I;  3P95 E;  1TCP A;  2IJO I;  2JOT A;  4ISN B;  2M99 A;  2LFL A;  1K6U A;  1TOC R;  4BNR I;  1F7Z I;  3BTT I;  1ZJD B;  3BTQ I;  3BTG I;  9PTI A;  5JB7 A;  1DEM A;  1BF0 A;  8PTI A; 
#chains in the Genus database with same CATH homology
 1CBW D;  4BQD A;  1EAW B;  1KNT A;  1DEN A;  1P2K I;  3FP8 I;  5PTI A;  5JB4 A;  1DTX A;  1T8O B;  2TPI I;  3L3T E;  1BUN B;  3BTM I;  1OA6 5;  2HEX A;  2KCR A;  2LFK A;  4Y11 I;  1BTI A;  2UUX A;  3AUC A;  1ADZ A;  4TPI I;  4Y10 I;  4WXV C;  4Y0Y I;  1P2N B;  2FI4 I;  4DG4 C;  1B0C A;  4Y0Z I;  4WWY C;  3LDJ A;  1KUN A;  2FTM B;  1OA5 5;  1T8L B;  1CO7 I;  3TGI I;  1Y62 A;  1FAK I;  3AUG A;  2ZJX A;  3UIR C;  1AAL A;  1MTN D;  1CA0 D;  4U30 W;  3WNY A;  1BRB I;  3FP6 I;  1TAW B;  1IRH A;  1UUB A;  1D0D A;  5C67 C;  4ISO B;  2ODY E;  3FP7 J;  5JB5 A;  3TGK I;  2M01 A;  1YC0 I;  3AUD A;  3OFW A;  3U1J E;  1DTK A;  1UUA A;  3BTD I;  1TFX C;  1KTH A;  1ZR0 B;  2CA7 A;  1BIK A;  1YKT B;  3BTE I;  7PTI A;  1FY8 I;  1BHC A;  1P2O B;  3BTH I;  4BD9 B;  1TPA I;  1BRC I;  2ZVX A;  4NTW B;  3BTW I;  5JB6 A;  1KIG I;  4U32 X;  1P2Q B;  3L33 E;  3LDI A;  2FTL I;  3D65 I;  2TGP I;  2R9P E;  3AUI A;  3P92 E;  1YLC B;  1JV9 A;  1TAP A;  1T8N B;  2FI5 I;  3GYM I;  4PTI A;  2DDJ A;  3BTF I;  2W8X A;  4DTG K;  4ISL B;  1YLD B;  1PIT A;  3AUH A;  1QLQ A;  1BZ5 A;  3BTK I;  3TGJ I;  2KAI I;  1BTH P;  1BPI A;  1JC6 A;  6PTI A;  4NTX B;  2KNT A;  3BYB A;  2UUY B;  2PTC I;  1LD5 A;  1T8M B;  3M7Q B;  3CI7 A;  1AAP A;  1D0D B;  1LD6 A;  2FI3 I;  1P2J I;  1T7C B;  3T62 D;  2DDI A;  3TPI I;  1BPT A;  1P2I I;  2RA3 C;  1G6X A;  1BZX I;  4NTY B;  1SHP A;  3AUB A;  1EJM B;  1F5R I;  1FAN A;  1JV8 A;  1NAG A;  3UOU B;  2J6D A;  3LDM A;  1P2M B;  3AUE A;  3OTJ I;  3P95 E;  1TCP A;  2IJO I;  2JOT A;  4ISN B;  2M99 A;  2LFL A;  1K6U A;  1TOC R;  4BNR I;  1F7Z I;  3BTT I;  1ZJD B;  3BTQ I;  3BTG I;  9PTI A;  5JB7 A;  1DEM A;  1BF0 A;  8PTI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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