3DXK | Genus

Total Genus 89

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	89
sequence length	282
structure length	282
Chain Sequence	MILLEVNNRIIEETLALKFENAAAGNKPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADELLKRVYGSYLVNPESGYNVSLLYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVFSTVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIGYITFVLFPRHTNASARDNTINLIHTFRDYLHYHIKCSKAYIHTRMRAKTSDFLKVLNRARP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

publication title	Characterization of two classes of small molecule inhibitors of Arp2/3 complex pubmed doi rcsb
molecule keywords	Actin-related protein 3
molecule tags	Structural protein
total genus	89
structure length	282
sequence length	282
ec nomenclature
pdb deposition date	2008-07-24

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
D	PF04045	P34-Arc	Arp2/3 complex, 34 kD subunit p34-Arc

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.30.1460.20	Alpha Beta	2-Layer Sandwich	Yope Regulator; Chain: A,	Yope Regulator; Chain: A,	3dxkD02
3.30.1460.20	Alpha Beta	2-Layer Sandwich	Yope Regulator; Chain: A,	Yope Regulator; Chain: A,	3dxkD01

1U2VD 3DXKF 2P9IF 2P9UF 3DWLF 2P9KF 2P9ID 2P9UD 3DWLD 3DXKD 4JD2F 2P9LF 2P9KD 2P9PF 4XEIF 4JD2D 3ULEF 3DXMF 2P9LD 2P9PD 1K8KF 3UKRF 4XEID 3RSEF 3UKUF 2P9NF 3DXMD 1TYQF 3ULED 1K8KD 3UKRD 3RSED 3UKUD 2P9ND 1TYQD 2P9SF 1U2VF 2P9SD
chains in the Genus database with same CATH superfamily

1JYOA 1K3EA 1U2VD 2BSHA 1K3SA 1K6ZA 2P9IF 2P9UF 3DWLF 3DXKF 2DYTA 4H5BA 3TU3A 3VX8B 1XKPB 1XKPC 2KC5A 2BSJA 2P9KF 2P9ID 2P9UD 3DWLD 1JYAA 3DXKD 4JD2F 2BSIA 2P9LF 1L2WA 2P9KD 2P9PF 2XGAA 3CXJA 4XEIF 4JD2D 3ULEF 3DXMF 2P9LD 4GSLC 1RY9A 2P9PD 4GF3A 1K8KF 3EPUA 4XEID 3RSEF 3UKRF 2P9NF 1S28A 3UKUF 3VX7B 3DXMD 4G6TA 1TYQF 4AKXA 2BHOA 3ULED 1K8KD 3UKRD 1TTWA 4JMFB 1N5BA 2P9ND 3RSED 3UKUD 4EBRA 1TYQD 2P9SF 2LPUA 2OD0A 2PLGA 3KXYA 1U2VF 2P9SD 2MQDA 2FM8A
chains in the Genus database with same CATH topology

1JYOA 1K3EA 1U2VD 2BSHA 1K3SA 1K6ZA 2P9IF 2P9UF 3DWLF 3DXKF 2DYTA 4H5BA 3TU3A 3VX8B 1XKPB 1XKPC 2KC5A 2BSJA 2P9KF 2P9ID 2P9UD 3DWLD 1JYAA 3DXKD 4JD2F 2BSIA 2P9LF 1L2WA 2P9KD 2P9PF 2XGAA 3CXJA 4XEIF 4JD2D 3ULEF 3DXMF 2P9LD 4GSLC 1RY9A 2P9PD 4GF3A 1K8KF 3EPUA 4XEID 3RSEF 3UKRF 2P9NF 1S28A 3UKUF 3VX7B 3DXMD 4G6TA 1TYQF 4AKXA 2BHOA 3ULED 1K8KD 3UKRD 1TTWA 4JMFB 1N5BA 2P9ND 3RSED 3UKUD 4EBRA 1TYQD 2P9SF 2LPUA 2PLGA 3KXYA 1U2VF 2P9SD 2MQDA 2FM8A
chains in the Genus database with same CATH homology

#chains in the Genus database with same CATH superfamily
 1U2V D;  3DXK F;  2P9I F;  2P9U F;  3DWL F;  2P9K F;  2P9I D;  2P9U D;  3DWL D;  3DXK D;  4JD2 F;  2P9L F;  2P9K D;  2P9P F;  4XEI F;  4JD2 D;  3ULE F;  3DXM F;  2P9L D;  2P9P D;  1K8K F;  3UKR F;  4XEI D;  3RSE F;  3UKU F;  2P9N F;  3DXM D;  1TYQ F;  3ULE D;  1K8K D;  3UKR D;  3RSE D;  3UKU D;  2P9N D;  1TYQ D;  2P9S F;  1U2V F;  2P9S D; 
#chains in the Genus database with same CATH topology
 1JYO A;  1K3E A;  1U2V D;  2BSH A;  1K3S A;  1K6Z A;  2P9I F;  2P9U F;  3DWL F;  3DXK F;  2DYT A;  4H5B A;  3TU3 A;  3VX8 B;  1XKP B;  1XKP C;  2KC5 A;  2BSJ A;  2P9K F;  2P9I D;  2P9U D;  3DWL D;  1JYA A;  3DXK D;  4JD2 F;  2BSI A;  2P9L F;  1L2W A;  2P9K D;  2P9P F;  2XGA A;  3CXJ A;  4XEI F;  4JD2 D;  3ULE F;  3DXM F;  2P9L D;  4GSL C;  1RY9 A;  2P9P D;  4GF3 A;  1K8K F;  3EPU A;  4XEI D;  3RSE F;  3UKR F;  2P9N F;  1S28 A;  3UKU F;  3VX7 B;  3DXM D;  4G6T A;  1TYQ F;  4AKX A;  2BHO A;  3ULE D;  1K8K D;  3UKR D;  1TTW A;  4JMF B;  1N5B A;  2P9N D;  3RSE D;  3UKU D;  4EBR A;  1TYQ D;  2P9S F;  2LPU A;  2OD0 A;  2PLG A;  3KXY A;  1U2V F;  2P9S D;  2MQD A;  2FM8 A; 
#chains in the Genus database with same CATH homology
 1JYO A;  1K3E A;  1U2V D;  2BSH A;  1K3S A;  1K6Z A;  2P9I F;  2P9U F;  3DWL F;  3DXK F;  2DYT A;  4H5B A;  3TU3 A;  3VX8 B;  1XKP B;  1XKP C;  2KC5 A;  2BSJ A;  2P9K F;  2P9I D;  2P9U D;  3DWL D;  1JYA A;  3DXK D;  4JD2 F;  2BSI A;  2P9L F;  1L2W A;  2P9K D;  2P9P F;  2XGA A;  3CXJ A;  4XEI F;  4JD2 D;  3ULE F;  3DXM F;  2P9L D;  4GSL C;  1RY9 A;  2P9P D;  4GF3 A;  1K8K F;  3EPU A;  4XEI D;  3RSE F;  3UKR F;  2P9N F;  1S28 A;  3UKU F;  3VX7 B;  3DXM D;  4G6T A;  1TYQ F;  4AKX A;  2BHO A;  3ULE D;  1K8K D;  3UKR D;  1TTW A;  4JMF B;  1N5B A;  2P9N D;  3RSE D;  3UKU D;  4EBR A;  1TYQ D;  2P9S F;  2LPU A;  2PLG A;  3KXY A;  1U2V F;  2P9S D;  2MQD A;  2FM8 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3DXKD

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations