3DXMF

Structure of bos taurus arp2/3 complex with bound inhibitor ck0993548
Total Genus 55
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
55
sequence length
167
structure length
167
Chain Sequence
TATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEKVLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITNFHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Characterization of two classes of small molecule inhibitors of Arp2/3 complex
pubmed doi rcsb
molecule tags Structural protein
molecule keywords Actin-related protein 3
total genus 55
structure length 167
sequence length 167
ec nomenclature
pdb deposition date 2008-07-24

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF05856 ARPC4 ARP2/3 complex 20 kDa subunit (ARPC4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.1460.20 Alpha Beta 2-Layer Sandwich Yope Regulator; Chain: A, Yope Regulator; Chain: A, 3dxmF00
2P9KF 2P9KD 3UKUF 4JD2F 3DXKF 3UKUD 4JD2D 1K8KF 3DXKD 2P9ND 2P9NF 3ULEF 1K8KD 3ULED 2P9PF 2P9UF 2P9UD 2P9PD 2P9SF 1TYQF 2P9SD 1TYQD 3DXMF 1U2VD 1U2VF 3DXMD 3RSEF 3UKRF 2P9LF 2P9LD 3UKRD 3RSED 4XEID 3DWLD 3DWLF 4XEIF 2P9IF 2P9ID
chains in the Genus database with same CATH superfamily
1JYAA 2P9KF 1TTWA 1XKPB 2P9KD 2BHOA 1XKPC 1JYOA 2FM8A 2OD0A 3UKUF 4H5BA 3CXJA 1L2WA 2XGAA 3DXKF 4JD2F 1K3EA 2MQDA 4JMFB 4GSLC 4JD2D 1K8KF 3DXKD 3UKUD 3VX8B 2P9ND 2P9NF 4G6TA 1K8KD 3KXYA 3ULEF 3ULED 2P9PF 2BSHA 2LPUA 2P9UF 2P9PD 2P9UD 2BSJA 2P9SF 1TYQF 2P9SD 1TYQD 1N5BA 3TU3A 2BSIA 3EPUA 4GF3A 3DXMF 3VX7B 4EBRA 1U2VF 1U2VD 2PLGA 3DXMD 3RSEF 1K6ZA 1K3SA 2P9LF 2P9LD 3UKRF 2KC5A 3RSED 3UKRD 2DYTA 1S28A 3DWLD 3DWLF 4XEID 4XEIF 4AKXA 2P9IF 1RY9A 2P9ID
chains in the Genus database with same CATH topology
1JYAA 2P9KF 1TTWA 1XKPB 2P9KD 2BHOA 1XKPC 1JYOA 2FM8A 3UKUF 4H5BA 3CXJA 1L2WA 2XGAA 3DXKF 4JD2F 1K3EA 2MQDA 4JMFB 4GSLC 4JD2D 1K8KF 3DXKD 3UKUD 3VX8B 2P9ND 2P9NF 4G6TA 1K8KD 3KXYA 3ULEF 3ULED 2P9PF 2BSHA 2LPUA 2P9UF 2P9PD 2P9UD 2BSJA 2P9SF 1TYQF 2P9SD 1TYQD 1N5BA 3TU3A 2BSIA 3EPUA 4GF3A 3DXMF 3VX7B 4EBRA 1U2VF 1U2VD 2PLGA 3DXMD 3RSEF 1K6ZA 1K3SA 2P9LF 2P9LD 3UKRF 2KC5A 3RSED 3UKRD 2DYTA 1S28A 3DWLD 3DWLF 4XEID 4XEIF 4AKXA 2P9IF 1RY9A 2P9ID
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P9K F;  2P9K D;  3UKU F;  4JD2 F;  3DXK F;  3UKU D;  4JD2 D;  1K8K F;  3DXK D;  2P9N D;  2P9N F;  3ULE F;  1K8K D;  3ULE D;  2P9P F;  2P9U F;  2P9U D;  2P9P D;  2P9S F;  1TYQ F;  2P9S D;  1TYQ D;  3DXM F;  1U2V D;  1U2V F;  3DXM D;  3RSE F;  3UKR F;  2P9L F;  2P9L D;  3UKR D;  3RSE D;  4XEI D;  3DWL D;  3DWL F;  4XEI F;  2P9I F;  2P9I D; 
#chains in the Genus database with same CATH topology
 1JYA A;  2P9K F;  1TTW A;  1XKP B;  2P9K D;  2BHO A;  1XKP C;  1JYO A;  2FM8 A;  2OD0 A;  3UKU F;  4H5B A;  3CXJ A;  1L2W A;  2XGA A;  3DXK F;  4JD2 F;  1K3E A;  2MQD A;  4JMF B;  4GSL C;  4JD2 D;  1K8K F;  3DXK D;  3UKU D;  3VX8 B;  2P9N D;  2P9N F;  4G6T A;  1K8K D;  3KXY A;  3ULE F;  3ULE D;  2P9P F;  2BSH A;  2LPU A;  2P9U F;  2P9P D;  2P9U D;  2BSJ A;  2P9S F;  1TYQ F;  2P9S D;  1TYQ D;  1N5B A;  3TU3 A;  2BSI A;  3EPU A;  4GF3 A;  3DXM F;  3VX7 B;  4EBR A;  1U2V F;  1U2V D;  2PLG A;  3DXM D;  3RSE F;  1K6Z A;  1K3S A;  2P9L F;  2P9L D;  3UKR F;  2KC5 A;  3RSE D;  3UKR D;  2DYT A;  1S28 A;  3DWL D;  3DWL F;  4XEI D;  4XEI F;  4AKX A;  2P9I F;  1RY9 A;  2P9I D; 
#chains in the Genus database with same CATH homology
 1JYA A;  2P9K F;  1TTW A;  1XKP B;  2P9K D;  2BHO A;  1XKP C;  1JYO A;  2FM8 A;  3UKU F;  4H5B A;  3CXJ A;  1L2W A;  2XGA A;  3DXK F;  4JD2 F;  1K3E A;  2MQD A;  4JMF B;  4GSL C;  4JD2 D;  1K8K F;  3DXK D;  3UKU D;  3VX8 B;  2P9N D;  2P9N F;  4G6T A;  1K8K D;  3KXY A;  3ULE F;  3ULE D;  2P9P F;  2BSH A;  2LPU A;  2P9U F;  2P9P D;  2P9U D;  2BSJ A;  2P9S F;  1TYQ F;  2P9S D;  1TYQ D;  1N5B A;  3TU3 A;  2BSI A;  3EPU A;  4GF3 A;  3DXM F;  3VX7 B;  4EBR A;  1U2V F;  1U2V D;  2PLG A;  3DXM D;  3RSE F;  1K6Z A;  1K3S A;  2P9L F;  2P9L D;  3UKR F;  2KC5 A;  3RSE D;  3UKR D;  2DYT A;  1S28 A;  3DWL D;  3DWL F;  4XEI D;  4XEI F;  4AKX A;  2P9I F;  1RY9 A;  2P9I D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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