3F6QB

Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
72
structure length
72
Chain Sequence
SENLYFQGSASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural basis of integrin-linked kinase-PINCH interactions.
pubmed doi rcsb
molecule tags Signaling protein/signaling protein
source organism Homo sapiens
molecule keywords Integrin-linked protein kinase
total genus 12
structure length 72
sequence length 72
ec nomenclature
pdb deposition date 2008-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 3f6qB00
1A7IA 1X3HA 1X68A 1U5SB 2CU8A 2DJ7A 1X62A 1X61A 1WYHA 3MMKA 3F6QB 2EGQA 2YPAC 4HI8B 1G47A 1B8TA 1X64A 2MIUA 1M3VA 2DFYC 2CURA 2L6ZC 2JTNA 4HI9B 2DLOA 2O10A 2KBXB 1X63A 2L6YB 3IXEB 1CTLA 2CORA 2XJZA 1NYPA 2O13A 2IYBE 1CXXA 1IBIA 2CUQA 2D8ZA 2D8XA 4JCJA 1V6GA 2MBVA 1X4LA 2EHEA 2XJYA 2D8YA 1QLIA 4KFZA 2L4ZA 1IMLA 2CO8A 2LXDA 1RUTX 1J2OA 1X6AA 2DARA 2XQNT 1WIGA 2LZUA 2CUPA
chains in the Genus database with same CATH superfamily
2CU8A 2XUEA 3AVSA 4EZ4A 2DFYC 2CURA 2L6ZC 2O10A 2KBXB 3IXEB 3ZPOA 2XJZA 2D8XA 2XJYA 2EHEA 1QLIA 5FP3A 5FXXA 2XQNT 3ZLIA 1A7IA 3NIJA 1X61A 2EGQA 4BHWA 1X64A 5LKXA 5FY1A 1M3VA 5FY0A 1CTLA 2CORA 1NYPA 2CUQA 3NIMA 2MBVA 3NIKA 1WIGA 4HI8B 2CUPA 3NILA 2DJ7A 1X3HA 3MMKA 1IMLA 1X62A 1G47A 5FXZA 4HI9B 4EZHA 2JTNA 2DLOA 5A1LA 1X63A 2IYBE 1CXXA 1IBIA 2D8ZA 4JCJA 1V6GA 1X4LA 2D8YA 2L4ZA 2CO8A 2LXDA 1RUTX 5LKZA 5FYMA 1X68A 1U5SB 4ASKA 3NISA 2YPAC 1WYHA 3F6QB 4UF0B 1B8TA 2MIUA 3NIHA 3AVRA 3NINA 2L6YB 5FXWA 5FXVA 2O13A 5LKUA 4KFZA 4UF0A 1J2OA 1X6AA 2DARA 5FY7A 2LZUA 5LKTA 4EYUA
chains in the Genus database with same CATH topology
2CU8A 2XUEA 3AVSA 4EZ4A 2DFYC 2CURA 2L6ZC 2O10A 2KBXB 3IXEB 3ZPOA 2XJZA 2D8XA 2XJYA 2EHEA 1QLIA 5FP3A 5FXXA 2XQNT 3ZLIA 1A7IA 3NIJA 1X61A 2EGQA 4BHWA 1X64A 5LKXA 5FY1A 1M3VA 5FY0A 1CTLA 2CORA 1NYPA 2CUQA 3NIMA 2MBVA 3NIKA 1WIGA 4HI8B 2CUPA 3NILA 2DJ7A 1X3HA 3MMKA 1IMLA 1X62A 1G47A 5FXZA 4HI9B 4EZHA 2JTNA 2DLOA 5A1LA 1X63A 2IYBE 1CXXA 1IBIA 2D8ZA 4JCJA 1V6GA 1X4LA 2D8YA 2L4ZA 2CO8A 2LXDA 1RUTX 5LKZA 5FYMA 1X68A 1U5SB 4ASKA 3NISA 2YPAC 1WYHA 3F6QB 4UF0B 1B8TA 2MIUA 3NIHA 3AVRA 3NINA 2L6YB 5FXWA 5FXVA 2O13A 5LKUA 4KFZA 4UF0A 1J2OA 1X6AA 2DARA 5FY7A 2LZUA 5LKTA 4EYUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1A7I A;  1X3H A;  1X68 A;  1U5S B;  2CU8 A;  2DJ7 A;  1X62 A;  1X61 A;  1WYH A;  3MMK A;  3F6Q B;  2EGQ A;  2YPA C;  4HI8 B;  1G47 A;  1B8T A;  1X64 A;  2MIU A;  1M3V A;  2DFY C;  2CUR A;  2L6Z C;  2JTN A;  4HI9 B;  2DLO A;  2O10 A;  2KBX B;  1X63 A;  2L6Y B;  3IXE B;  1CTL A;  2COR A;  2XJZ A;  1NYP A;  2O13 A;  2IYB E;  1CXX A;  1IBI A;  2CUQ A;  2D8Z A;  2D8X A;  4JCJ A;  1V6G A;  2MBV A;  1X4L A;  2EHE A;  2XJY A;  2D8Y A;  1QLI A;  4KFZ A;  2L4Z A;  1IML A;  2CO8 A;  2LXD A;  1RUT X;  1J2O A;  1X6A A;  2DAR A;  2XQN T;  1WIG A;  2LZU A;  2CUP A; 
#chains in the Genus database with same CATH topology
 2CU8 A;  2XUE A;  3AVS A;  4EZ4 A;  2DFY C;  2CUR A;  2L6Z C;  2O10 A;  2KBX B;  3IXE B;  3ZPO A;  2XJZ A;  2D8X A;  2XJY A;  2EHE A;  1QLI A;  5FP3 A;  5FXX A;  2XQN T;  3ZLI A;  1A7I A;  3NIJ A;  1X61 A;  2EGQ A;  4BHW A;  1X64 A;  5LKX A;  5FY1 A;  1M3V A;  5FY0 A;  1CTL A;  2COR A;  1NYP A;  2CUQ A;  3NIM A;  2MBV A;  3NIK A;  1WIG A;  4HI8 B;  2CUP A;  3NIL A;  2DJ7 A;  1X3H A;  3MMK A;  1IML A;  1X62 A;  1G47 A;  5FXZ A;  4HI9 B;  4EZH A;  2JTN A;  2DLO A;  5A1L A;  1X63 A;  2IYB E;  1CXX A;  1IBI A;  2D8Z A;  4JCJ A;  1V6G A;  1X4L A;  2D8Y A;  2L4Z A;  2CO8 A;  2LXD A;  1RUT X;  5LKZ A;  5FYM A;  1X68 A;  1U5S B;  4ASK A;  3NIS A;  2YPA C;  1WYH A;  3F6Q B;  4UF0 B;  1B8T A;  2MIU A;  3NIH A;  3AVR A;  3NIN A;  2L6Y B;  5FXW A;  5FXV A;  2O13 A;  5LKU A;  4KFZ A;  4UF0 A;  1J2O A;  1X6A A;  2DAR A;  5FY7 A;  2LZU A;  5LKT A;  4EYU A; 
#chains in the Genus database with same CATH homology
 2CU8 A;  2XUE A;  3AVS A;  4EZ4 A;  2DFY C;  2CUR A;  2L6Z C;  2O10 A;  2KBX B;  3IXE B;  3ZPO A;  2XJZ A;  2D8X A;  2XJY A;  2EHE A;  1QLI A;  5FP3 A;  5FXX A;  2XQN T;  3ZLI A;  1A7I A;  3NIJ A;  1X61 A;  2EGQ A;  4BHW A;  1X64 A;  5LKX A;  5FY1 A;  1M3V A;  5FY0 A;  1CTL A;  2COR A;  1NYP A;  2CUQ A;  3NIM A;  2MBV A;  3NIK A;  1WIG A;  4HI8 B;  2CUP A;  3NIL A;  2DJ7 A;  1X3H A;  3MMK A;  1IML A;  1X62 A;  1G47 A;  5FXZ A;  4HI9 B;  4EZH A;  2JTN A;  2DLO A;  5A1L A;  1X63 A;  2IYB E;  1CXX A;  1IBI A;  2D8Z A;  4JCJ A;  1V6G A;  1X4L A;  2D8Y A;  2L4Z A;  2CO8 A;  2LXD A;  1RUT X;  5LKZ A;  5FYM A;  1X68 A;  1U5S B;  4ASK A;  3NIS A;  2YPA C;  1WYH A;  3F6Q B;  4UF0 B;  1B8T A;  2MIU A;  3NIH A;  3AVR A;  3NIN A;  2L6Y B;  5FXW A;  5FXV A;  2O13 A;  5LKU A;  4KFZ A;  4UF0 A;  1J2O A;  1X6A A;  2DAR A;  5FY7 A;  2LZU A;  5LKT A;  4EYU A; 
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