3F6QB

Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with pinch1 lim1 domain
Total Genus 12
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
12
sequence length
72
structure length
72
Chain Sequence
SENLYFQGSASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The structural basis of integrin-linked kinase-PINCH interactions.
pubmed doi rcsb
molecule tags Signaling protein/signaling protein
source organism Homo sapiens
molecule keywords Integrin-linked protein kinase
total genus 12
structure length 72
sequence length 72
ec nomenclature
pdb deposition date 2008-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00412 LIM LIM domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.110.10 Mainly Beta Ribbon Cysteine Rich Protein Cysteine Rich Protein 3f6qB00
3MMKA 1V6GA 4HI9B 1B8TA 1X4LA 2L4ZA 2CU8A 2DLOA 2CUQA 1X68A 2DJ7A 1QLIA 4KFZA 2XJZA 1CTLA 2DARA 2KBXB 2O10A 4JCJA 1IBIA 2MBVA 4HI8B 1M3VA 1G47A 3F6QB 2YPAC 1X63A 1X64A 1NYPA 1X3HA 1J2OA 1CXXA 2D8ZA 2CURA 2L6ZC 2CORA 2XQNT 1RUTX 2EHEA 1IMLA 1WYHA 1X61A 2CO8A 3IXEB 2D8YA 2L6YB 1X6AA 1X62A 2JTNA 2O13A 2CUPA 2EGQA 2XJYA 1WIGA 1A7IA 2LXDA 2LZUA 2D8XA 2IYBE 2DFYC 1U5SB 2MIUA
chains in the Genus database with same CATH superfamily
1V6GA 2DLOA 5LKUA 2CUQA 2XJZA 5FXZA 2O10A 2KBXB 2MBVA 4EZ4A 1CXXA 2D8ZA 1IMLA 5LKXA 2XQNT 2EHEA 3NINA 1X61A 5LKTA 2D8YA 1X62A 2EGQA 3MMKA 5FXXA 1B8TA 2L4ZA 2CU8A 1X68A 5FY1A 1QLIA 3ZPOA 4EYUA 3NIKA 1X63A 1NYPA 4EZHA 2CURA 2L6ZC 1RUTX 2CO8A 2L6YB 1X6AA 2O13A 2XJYA 3NIMA 1A7IA 2LZUA 2D8XA 2DFYC 5FY0A 4HI9B 3AVSA 5A1LA 1CTLA 4JCJA 1IBIA 5LKZA 4BHWA 1G47A 3F6QB 1X64A 1J2OA 3NIJA 2CORA 1WYHA 3AVRA 4UF0A 2JTNA 2CUPA 5FXWA 5FYMA 3ZLIA 4UF0B 2IYBE 1X4LA 2DJ7A 4KFZA 2XUEA 5FY7A 2DARA 3NISA 3NILA 4HI8B 1M3VA 5FXVA 2YPAC 1X3HA 5FP3A 3NIHA 3IXEB 1WIGA 2LXDA 4ASKA 1U5SB 2MIUA
chains in the Genus database with same CATH topology
1V6GA 2DLOA 5LKUA 2CUQA 2XJZA 5FXZA 2O10A 2KBXB 2MBVA 4EZ4A 1CXXA 2D8ZA 1IMLA 5LKXA 2XQNT 2EHEA 3NINA 1X61A 5LKTA 2D8YA 1X62A 2EGQA 3MMKA 5FXXA 1B8TA 2L4ZA 2CU8A 1X68A 5FY1A 1QLIA 3ZPOA 4EYUA 3NIKA 1X63A 1NYPA 4EZHA 2CURA 2L6ZC 1RUTX 2CO8A 2L6YB 1X6AA 2O13A 2XJYA 3NIMA 1A7IA 2LZUA 2D8XA 2DFYC 5FY0A 4HI9B 3AVSA 5A1LA 1CTLA 4JCJA 1IBIA 5LKZA 4BHWA 1G47A 3F6QB 1X64A 1J2OA 3NIJA 2CORA 1WYHA 3AVRA 4UF0A 2JTNA 2CUPA 5FXWA 5FYMA 3ZLIA 4UF0B 2IYBE 1X4LA 2DJ7A 4KFZA 2XUEA 5FY7A 2DARA 3NISA 3NILA 4HI8B 1M3VA 5FXVA 2YPAC 1X3HA 5FP3A 3NIHA 3IXEB 1WIGA 2LXDA 4ASKA 1U5SB 2MIUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MMK A;  1V6G A;  4HI9 B;  1B8T A;  1X4L A;  2L4Z A;  2CU8 A;  2DLO A;  2CUQ A;  1X68 A;  2DJ7 A;  1QLI A;  4KFZ A;  2XJZ A;  1CTL A;  2DAR A;  2KBX B;  2O10 A;  4JCJ A;  1IBI A;  2MBV A;  4HI8 B;  1M3V A;  1G47 A;  3F6Q B;  2YPA C;  1X63 A;  1X64 A;  1NYP A;  1X3H A;  1J2O A;  1CXX A;  2D8Z A;  2CUR A;  2L6Z C;  2COR A;  2XQN T;  1RUT X;  2EHE A;  1IML A;  1WYH A;  1X61 A;  2CO8 A;  3IXE B;  2D8Y A;  2L6Y B;  1X6A A;  1X62 A;  2JTN A;  2O13 A;  2CUP A;  2EGQ A;  2XJY A;  1WIG A;  1A7I A;  2LXD A;  2LZU A;  2D8X A;  2IYB E;  2DFY C;  1U5S B;  2MIU A; 
#chains in the Genus database with same CATH topology
 1V6G A;  2DLO A;  5LKU A;  2CUQ A;  2XJZ A;  5FXZ A;  2O10 A;  2KBX B;  2MBV A;  4EZ4 A;  1CXX A;  2D8Z A;  1IML A;  5LKX A;  2XQN T;  2EHE A;  3NIN A;  1X61 A;  5LKT A;  2D8Y A;  1X62 A;  2EGQ A;  3MMK A;  5FXX A;  1B8T A;  2L4Z A;  2CU8 A;  1X68 A;  5FY1 A;  1QLI A;  3ZPO A;  4EYU A;  3NIK A;  1X63 A;  1NYP A;  4EZH A;  2CUR A;  2L6Z C;  1RUT X;  2CO8 A;  2L6Y B;  1X6A A;  2O13 A;  2XJY A;  3NIM A;  1A7I A;  2LZU A;  2D8X A;  2DFY C;  5FY0 A;  4HI9 B;  3AVS A;  5A1L A;  1CTL A;  4JCJ A;  1IBI A;  5LKZ A;  4BHW A;  1G47 A;  3F6Q B;  1X64 A;  1J2O A;  3NIJ A;  2COR A;  1WYH A;  3AVR A;  4UF0 A;  2JTN A;  2CUP A;  5FXW A;  5FYM A;  3ZLI A;  4UF0 B;  2IYB E;  1X4L A;  2DJ7 A;  4KFZ A;  2XUE A;  5FY7 A;  2DAR A;  3NIS A;  3NIL A;  4HI8 B;  1M3V A;  5FXV A;  2YPA C;  1X3H A;  5FP3 A;  3NIH A;  3IXE B;  1WIG A;  2LXD A;  4ASK A;  1U5S B;  2MIU A; 
#chains in the Genus database with same CATH homology
 1V6G A;  2DLO A;  5LKU A;  2CUQ A;  2XJZ A;  5FXZ A;  2O10 A;  2KBX B;  2MBV A;  4EZ4 A;  1CXX A;  2D8Z A;  1IML A;  5LKX A;  2XQN T;  2EHE A;  3NIN A;  1X61 A;  5LKT A;  2D8Y A;  1X62 A;  2EGQ A;  3MMK A;  5FXX A;  1B8T A;  2L4Z A;  2CU8 A;  1X68 A;  5FY1 A;  1QLI A;  3ZPO A;  4EYU A;  3NIK A;  1X63 A;  1NYP A;  4EZH A;  2CUR A;  2L6Z C;  1RUT X;  2CO8 A;  2L6Y B;  1X6A A;  2O13 A;  2XJY A;  3NIM A;  1A7I A;  2LZU A;  2D8X A;  2DFY C;  5FY0 A;  4HI9 B;  3AVS A;  5A1L A;  1CTL A;  4JCJ A;  1IBI A;  5LKZ A;  4BHW A;  1G47 A;  3F6Q B;  1X64 A;  1J2O A;  3NIJ A;  2COR A;  1WYH A;  3AVR A;  4UF0 A;  2JTN A;  2CUP A;  5FXW A;  5FYM A;  3ZLI A;  4UF0 B;  2IYB E;  1X4L A;  2DJ7 A;  4KFZ A;  2XUE A;  5FY7 A;  2DAR A;  3NIS A;  3NIL A;  4HI8 B;  1M3V A;  5FXV A;  2YPA C;  1X3H A;  5FP3 A;  3NIH A;  3IXE B;  1WIG A;  2LXD A;  4ASK A;  1U5S B;  2MIU A; 
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