3FHHA

Crystal structure of the heme/hemoglobin outer membrane transporter shua from shigella dysenteriae
Total Genus 163
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
163
sequence length
640
structure length
621
Chain Sequence
TETMTVTATGNARSSFEAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTGRTNGQDINMRGYDHRGVLVLVDGIRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQEGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPNDESINNMLAKGTWQIDSAQSLSGLVRYYNNDAREPKNPQTVEASESSNPMVDRSTIQRDAQLSYKLAPQGNDWLNADAKIYWSEVRINAQEYREQITKGARLENRSTLFADSFASHLLTYGGEYYRQEQGSHTTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRYDSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFSIGRFYTNYWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASYFDTKAKDYISTTVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEYISSINPDTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSKQPGYGVNDFYVSYQGQQALKGMTTTLVLGNAFDKEYWSPQGIPQDGRNGKIFVSYQW
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of the heme/hemoglobin outer membrane transporter ShuA from the human pathogen /Shigella dysenteriae /bound to divalent cations: heme binding by an extracellular induced fit mechanism
rcsb
molecule tags Membrane protein
source organism Shigella dysenteriae
molecule keywords Outer membrane heme receptor ShuA
total genus 163
structure length 621
sequence length 640
ec nomenclature
pdb deposition date 2008-12-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 3fhhA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 3fhhA01
2W75A 2HDIA 4RDRA 2W78A 2GRXA 1NQHA 2GSKA 2GUFA 3EFMA 3RGMA 4B7OA 1QKCA 2W77A 1UJWA 1PO3A 1KMPA 5FOKA 1FI1A 1XKHA 1QFFA 2W16A 1BY3A 3DDRA 2W76A 1FEPA 1QJQA 2HDFA 4CU4A 1KMOA 1XKWA 1QFGA 3M8BA 1NQEA 2YSUA 3V8XA 3M8DA 2FCPA 2W6TA 3CSNA 2W6UA 1FCPA 1NQGA 1PNZA 2O5PA 3V89A 1BY5A 4RDTA 2IAHA 1NQFA 3FHHA 4AIQA 3RGNA 3QLBA 4AIPA 4EPAA 3CSLA 1PO0A
chains in the Genus database with same CATH superfamily
1MPOA 2W75A 1OH2P 2HDIA 4RDRA 2W78A 2GRXA 1NQHA 2GSKA 2GUFA 3EFMA 3RGMA 4B7OA 1QKCA 2W77A 1UJWA 1PO3A 1KMPA 5FOKA 1MPQA 1FI1A 1XKHA 1MALA 1QFFA 2W16A 1BY3A 3DDRA 2W76A 1FEPA 1QJQA 2HDFA 4CU4A 1KMOA 1MPRA 1XKWA 1QFGA 3M8BA 1JBIA 1NQEA 1MPNA 1MPMA 2YSUA 3V8XA 2MPRA 3M8DA 2FCPA 1AF6A 2W6TA 3CSNA 1A0SP 2W6UA 1FCPA 1NQGA 1PNZA 2O5PA 3V89A 1OH2Q 1BY5A 4RDTA 2IAHA 1NQFA 3FHHA 4AIQA 3RGNA 3QLBA 4AIPA 1A0TP 4EPAA 3CSLA 1PO0A
chains in the Genus database with same CATH topology
2W75A 2HDIA 4RDRA 2W78A 2GRXA 1NQHA 2GSKA 2GUFA 3EFMA 3RGMA 4B7OA 1QKCA 2W77A 1UJWA 1PO3A 1KMPA 5FOKA 1FI1A 1XKHA 1QFFA 2W16A 1BY3A 3DDRA 2W76A 1FEPA 1QJQA 2HDFA 4CU4A 1KMOA 1XKWA 1QFGA 3M8BA 1NQEA 2YSUA 3V8XA 3M8DA 2FCPA 2W6TA 3CSNA 2W6UA 1FCPA 1NQGA 1PNZA 2O5PA 3V89A 1BY5A 4RDTA 2IAHA 1NQFA 3FHHA 4AIQA 3RGNA 3QLBA 4AIPA 4EPAA 3CSLA 1PO0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W75 A;  2HDI A;  4RDR A;  2W78 A;  2GRX A;  1NQH A;  2GSK A;  2GUF A;  3EFM A;  3RGM A;  4B7O A;  1QKC A;  2W77 A;  1UJW A;  1PO3 A;  1KMP A;  5FOK A;  1FI1 A;  1XKH A;  1QFF A;  2W16 A;  1BY3 A;  3DDR A;  2W76 A;  1FEP A;  1QJQ A;  2HDF A;  4CU4 A;  1KMO A;  1XKW A;  1QFG A;  3M8B A;  1NQE A;  2YSU A;  3V8X A;  3M8D A;  2FCP A;  2W6T A;  3CSN A;  2W6U A;  1FCP A;  1NQG A;  1PNZ A;  2O5P A;  3V89 A;  1BY5 A;  4RDT A;  2IAH A;  1NQF A;  3FHH A;  4AIQ A;  3RGN A;  3QLB A;  4AIP A;  4EPA A;  3CSL A;  1PO0 A; 
#chains in the Genus database with same CATH topology
 1MPO A;  2W75 A;  1OH2 P;  2HDI A;  4RDR A;  2W78 A;  2GRX A;  1NQH A;  2GSK A;  2GUF A;  3EFM A;  3RGM A;  4B7O A;  1QKC A;  2W77 A;  1UJW A;  1PO3 A;  1KMP A;  5FOK A;  1MPQ A;  1FI1 A;  1XKH A;  1MAL A;  1QFF A;  2W16 A;  1BY3 A;  3DDR A;  2W76 A;  1FEP A;  1QJQ A;  2HDF A;  4CU4 A;  1KMO A;  1MPR A;  1XKW A;  1QFG A;  3M8B A;  1JBI A;  1NQE A;  1MPN A;  1MPM A;  2YSU A;  3V8X A;  2MPR A;  3M8D A;  2FCP A;  1AF6 A;  2W6T A;  3CSN A;  1A0S P;  2W6U A;  1FCP A;  1NQG A;  1PNZ A;  2O5P A;  3V89 A;  1OH2 Q;  1BY5 A;  4RDT A;  2IAH A;  1NQF A;  3FHH A;  4AIQ A;  3RGN A;  3QLB A;  4AIP A;  1A0T P;  4EPA A;  3CSL A;  1PO0 A; 
#chains in the Genus database with same CATH homology
 2W75 A;  2HDI A;  4RDR A;  2W78 A;  2GRX A;  1NQH A;  2GSK A;  2GUF A;  3EFM A;  3RGM A;  4B7O A;  1QKC A;  2W77 A;  1UJW A;  1PO3 A;  1KMP A;  5FOK A;  1FI1 A;  1XKH A;  1QFF A;  2W16 A;  1BY3 A;  3DDR A;  2W76 A;  1FEP A;  1QJQ A;  2HDF A;  4CU4 A;  1KMO A;  1XKW A;  1QFG A;  3M8B A;  1NQE A;  2YSU A;  3V8X A;  3M8D A;  2FCP A;  2W6T A;  3CSN A;  2W6U A;  1FCP A;  1NQG A;  1PNZ A;  2O5P A;  3V89 A;  1BY5 A;  4RDT A;  2IAH A;  1NQF A;  3FHH A;  4AIQ A;  3RGN A;  3QLB A;  4AIP A;  4EPA A;  3CSL A;  1PO0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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