3GTOE

Backtracked rna polymerase ii complex with 15mer rna
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription, transferase/dna-rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 39
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3gtoE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3gtoE02
4A93E 4BXXE 1EIKA 4A3ME 5IP7E 3S1RE 1TWCE 3M3YE 3H0GE 4C3HE 2Y0SH 4A3GE 5C3EE 5C4JE 3M4OE 4A3CE 1SFOE 2YU9E 1Y1WE 3HOZE 5C4XE 5FLME 5IP9E 3GTOE 2B63E 2WB1H 1I50E 3K7AE 3HOYE 3RZOE 3I4ME 3GTJE 4A3DE 5IYDE 1R9TE 3S14E 4C2ME 3S2HE 5IYCE 4A3FE 4BBSE 1TWAE 5FJ8E 3PO3E 3S1NE 2JA8E 1TWGE 3HOVE 4A3IE 2JA7E 2R7ZE 2JA6E 3HOUE 4A3BE 2NVYE 1K83E 5M5XE 3CQZE 1TWHE 3GTGE 4Y52E 3I4NE 3S2DE 3HOXE 3PO2E 4X6AE 5M3ME 4A3JE 4C3IE 2WAQH 4A3EE 1I3QE 4Y7NE 3GTME 3GTPE 3HOWE 2R92E 2E2IE 2E2HE 3RZDE 3S1QE 3S15E 2PMZH 2NVXE 5C44E 4QIWH 4A3KE 5IYBE 2E2JE 3GTQE 2JA5E 1TWFE 3S1ME 1Y1VE 3H3VF 4C3JE 5M5YE 4A3LE 3S17E 3S16E 3GTKE 1DZFA 4AYBH 5M5WE 1WCME 2NVTE 2NVQE 4BBRE 3FKIE 4BY1E 2VUME 2R93E 4BY7E 3GTLE 5M3FE 1I6HE 3HKZH
chains in the Genus database with same CATH superfamily
4A93E 3I4MF 4BXXE 4A3DF 1EIKA 4A3ME 4YG2E 1R9TF 5IP7E 3S1RE 1TWCE 3M3YE 3H0GE 2YU9F 3S2HF 4KMUE 4ZH4E 5IYCF 4A3FF 4C3HE 4BBSF 1TWAF 2Y0SH 4A3GE 1YNJK 5C3EE 5C4JE 5FJ8F 3PO3F 3S1NF 4A93F 3M4OE 4A3CE 1TWGF 4MQ9E 4A3MF 1SFOE 2YU9E 3HOVF 4G7OE 5IP7F 1TWCF 1Y1WE 3HOZE 2JA6F 5C4XE 5FLME 1I6VE 5IP9E 3GTOE 3HOUF 2O5JE 4C3HF 4A3BF 2B63E 1IW7E 5C3EF 2WB1H 5C4JF 5IPLE 1I50E 3K7AE 3HOYE 3RZOE 3I4ME 2NVYF 3GTJE 3CQZF 5M5XF 4A3DE 1TWHF 4MEXE 4OIRE 3HOZF 5IYDE 1R9TE 3S14E 1YNNK 4Y52F 5FLMF 3GTGF 3GTOF 3I4NF 3HOXF 3PO2F 4JK1E 4C2ME 3S2HE 5M3MF 4X6AF 5IYCE 4A3FE 4BBSE 4A3JF 4GZYE 1TWAE 5FJ8E 4A3EF 3PO3E 3S1NE 2JA8E 4AYBK 3GTJF 3RZOF 2PMZK 1TWGE 3HOVE 5IYDF 3S14F 4A3IE 5TMCE 3GTMF 3GTPF 3HOWF 2JA7E 2R92F 5D4EE 2R7ZE 2JA6E 4C2MF 2E2HF 3HOUE 4A3BE 4QIWK 3K7AF 2JA8F 4YFNE 4KN7E 2PPBE 2NVYE 1K83E 5M5XE 3CQZE 4A3IF 1TWHE 2JA7F 5C44F 3GTGE 2R7ZF 4Y52E 3I4NE 3S2DE 3HOXE 3PO2E 4A3KF 4X6AE 1SMYE 5M3ME 2BE5E 2CW0E 4LJZE 4A3JE 5TMFE 4C3IE 5E18E 2E2JF 3GTQF 2WAQH 4A3EE 1K83F 3WODE 1I3QE 4Y7NE 2Y0SI 3GTME 3GTPE 3HOWE 2R92E 4YFXE 2E2IE 5D4CE 3S1MF 2E2HE 3S2DF 1Y1VF 3HKZK 4LK1E 3RZDE 3S1QE 2A69E 3S15E 2PMZH 1QKLA 4C3IF 4YFKE 5M5YF 3S17F 4A3LF 4XSZE 1I3QF 3S16F 4Y7NF 2NVXE 2A68E 3GTKF 2WB1I 5C44E 1ZYRE 4QIWH 2E2IF 3RZDF 3S1QF 4A3KE 4G7HE 3S15F 5M5WF 3DXJE 5IYBE 2E2JE 4MEYE 3GTQE 2NVXF 1WCMF 4XSXE 4Q5SE 3H3VG 2O5IE 2JA5E 4LLGE 1TWFE 3S1ME 2A6HE 1Y1VE 2A6EE 4BBRF 5IYBF 4OINE 4OIQE 3H3VF 4C3JE 5M5YE 3FKIF 4A3LE 3S17E 4KN4E 3S16E 4BY1F 2VUMF 3GTKE 2JA5F 1TWFF 1DZFA 5BYHE 2R93F 4G7ZE 4BY7F 4AYBH 5M5WE 4C3JF 3GTLF 5M3FF 4OIPE 5D4DE 1I6HF 1WCME 4LK0E 4BXXF 2KRXA 2NVTE 4OIOE 3S1RF 3M3YF 3H0GF 2NVQE 4BBRE 3FKIE 4A3GF 5E17E 4BY1E 2VUME 1HQME 3M4OF 4A3CF 1SFOF 2NVTF 4XLNE 2R93E 1Y1WF 4BY7E 2WAQK 5C4XF 5IP9F 2NVQF 3GTLE 3EQLE 4XLPE 2B63F 4Q4ZE 5M3FE 1I50F 1I6HE 3HOYF 3HKZH
chains in the Genus database with same CATH topology
4A93E 4BXXE 1EIKA 4A3ME 5IP7E 3S1RE 1TWCE 3M3YE 3H0GE 4C3HE 2Y0SH 4A3GE 5C3EE 5C4JE 3M4OE 4A3CE 1SFOE 2YU9E 1Y1WE 3HOZE 5C4XE 5FLME 5IP9E 3GTOE 2B63E 2WB1H 1I50E 3K7AE 3HOYE 3RZOE 3I4ME 3GTJE 4A3DE 5IYDE 1R9TE 3S14E 4C2ME 3S2HE 5IYCE 4A3FE 4BBSE 1TWAE 5FJ8E 3PO3E 3S1NE 2JA8E 1TWGE 3HOVE 4A3IE 2JA7E 2R7ZE 2JA6E 3HOUE 4A3BE 2NVYE 1K83E 5M5XE 3CQZE 1TWHE 3GTGE 4Y52E 3I4NE 3S2DE 3HOXE 3PO2E 4X6AE 5M3ME 4A3JE 4C3IE 2WAQH 4A3EE 1I3QE 4Y7NE 3GTME 3GTPE 3HOWE 2R92E 2E2IE 2E2HE 3RZDE 3S1QE 3S15E 2PMZH 2NVXE 5C44E 4QIWH 4A3KE 5IYBE 2E2JE 3GTQE 2JA5E 1TWFE 3S1ME 1Y1VE 3H3VF 4C3JE 5M5YE 4A3LE 3S17E 3S16E 3GTKE 1DZFA 4AYBH 5M5WE 1WCME 2NVTE 2NVQE 4BBRE 3FKIE 4BY1E 2VUME 2R93E 4BY7E 3GTLE 5M3FE 1I6HE 3HKZH
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A93 E;  4BXX E;  1EIK A;  4A3M E;  5IP7 E;  3S1R E;  1TWC E;  3M3Y E;  3H0G E;  4C3H E;  2Y0S H;  4A3G E;  5C3E E;  5C4J E;  3M4O E;  4A3C E;  1SFO E;  2YU9 E;  1Y1W E;  3HOZ E;  5C4X E;  5FLM E;  5IP9 E;  3GTO E;  2B63 E;  2WB1 H;  1I50 E;  3K7A E;  3HOY E;  3RZO E;  3I4M E;  3GTJ E;  4A3D E;  5IYD E;  1R9T E;  3S14 E;  4C2M E;  3S2H E;  5IYC E;  4A3F E;  4BBS E;  1TWA E;  5FJ8 E;  3PO3 E;  3S1N E;  2JA8 E;  1TWG E;  3HOV E;  4A3I E;  2JA7 E;  2R7Z E;  2JA6 E;  3HOU E;  4A3B E;  2NVY E;  1K83 E;  5M5X E;  3CQZ E;  1TWH E;  3GTG E;  4Y52 E;  3I4N E;  3S2D E;  3HOX E;  3PO2 E;  4X6A E;  5M3M E;  4A3J E;  4C3I E;  2WAQ H;  4A3E E;  1I3Q E;  4Y7N E;  3GTM E;  3GTP E;  3HOW E;  2R92 E;  2E2I E;  2E2H E;  3RZD E;  3S1Q E;  3S15 E;  2PMZ H;  2NVX E;  5C44 E;  4QIW H;  4A3K E;  5IYB E;  2E2J E;  3GTQ E;  2JA5 E;  1TWF E;  3S1M E;  1Y1V E;  3H3V F;  4C3J E;  5M5Y E;  4A3L E;  3S17 E;  3S16 E;  3GTK E;  1DZF A;  4AYB H;  5M5W E;  1WCM E;  2NVT E;  2NVQ E;  4BBR E;  3FKI E;  4BY1 E;  2VUM E;  2R93 E;  4BY7 E;  3GTL E;  5M3F E;  1I6H E;  3HKZ H; 
#chains in the Genus database with same CATH topology
 4A93 E;  3I4M F;  4BXX E;  4A3D F;  1EIK A;  4A3M E;  4YG2 E;  1R9T F;  5IP7 E;  3S1R E;  1TWC E;  3M3Y E;  3H0G E;  2YU9 F;  3S2H F;  4KMU E;  4ZH4 E;  5IYC F;  4A3F F;  4C3H E;  4BBS F;  1TWA F;  2Y0S H;  4A3G E;  1YNJ K;  5C3E E;  5C4J E;  5FJ8 F;  3PO3 F;  3S1N F;  4A93 F;  3M4O E;  4A3C E;  1TWG F;  4MQ9 E;  4A3M F;  1SFO E;  2YU9 E;  3HOV F;  4G7O E;  5IP7 F;  1TWC F;  1Y1W E;  3HOZ E;  2JA6 F;  5C4X E;  5FLM E;  1I6V E;  5IP9 E;  3GTO E;  3HOU F;  2O5J E;  4C3H F;  4A3B F;  2B63 E;  1IW7 E;  5C3E F;  2WB1 H;  5C4J F;  5IPL E;  1I50 E;  3K7A E;  3HOY E;  3RZO E;  3I4M E;  2NVY F;  3GTJ E;  3CQZ F;  5M5X F;  4A3D E;  1TWH F;  4MEX E;  4OIR E;  3HOZ F;  5IYD E;  1R9T E;  3S14 E;  1YNN K;  4Y52 F;  5FLM F;  3GTG F;  3GTO F;  3I4N F;  3HOX F;  3PO2 F;  4JK1 E;  4C2M E;  3S2H E;  5M3M F;  4X6A F;  5IYC E;  4A3F E;  4BBS E;  4A3J F;  4GZY E;  1TWA E;  5FJ8 E;  4A3E F;  3PO3 E;  3S1N E;  2JA8 E;  4AYB K;  3GTJ F;  3RZO F;  2PMZ K;  1TWG E;  3HOV E;  5IYD F;  3S14 F;  4A3I E;  5TMC E;  3GTM F;  3GTP F;  3HOW F;  2JA7 E;  2R92 F;  5D4E E;  2R7Z E;  2JA6 E;  4C2M F;  2E2H F;  3HOU E;  4A3B E;  4QIW K;  3K7A F;  2JA8 F;  4YFN E;  4KN7 E;  2PPB E;  2NVY E;  1K83 E;  5M5X E;  3CQZ E;  4A3I F;  1TWH E;  2JA7 F;  5C44 F;  3GTG E;  2R7Z F;  4Y52 E;  3I4N E;  3S2D E;  3HOX E;  3PO2 E;  4A3K F;  4X6A E;  1SMY E;  5M3M E;  2BE5 E;  2CW0 E;  4LJZ E;  4A3J E;  5TMF E;  4C3I E;  5E18 E;  2E2J F;  3GTQ F;  2WAQ H;  4A3E E;  1K83 F;  3WOD E;  1I3Q E;  4Y7N E;  2Y0S I;  3GTM E;  3GTP E;  3HOW E;  2R92 E;  4YFX E;  2E2I E;  5D4C E;  3S1M F;  2E2H E;  3S2D F;  1Y1V F;  3HKZ K;  4LK1 E;  3RZD E;  3S1Q E;  2A69 E;  3S15 E;  2PMZ H;  1QKL A;  4C3I F;  4YFK E;  5M5Y F;  3S17 F;  4A3L F;  4XSZ E;  1I3Q F;  3S16 F;  4Y7N F;  2NVX E;  2A68 E;  3GTK F;  2WB1 I;  5C44 E;  1ZYR E;  4QIW H;  2E2I F;  3RZD F;  3S1Q F;  4A3K E;  4G7H E;  3S15 F;  5M5W F;  3DXJ E;  5IYB E;  2E2J E;  4MEY E;  3GTQ E;  2NVX F;  1WCM F;  4XSX E;  4Q5S E;  3H3V G;  2O5I E;  2JA5 E;  4LLG E;  1TWF E;  3S1M E;  2A6H E;  1Y1V E;  2A6E E;  4BBR F;  5IYB F;  4OIN E;  4OIQ E;  3H3V F;  4C3J E;  5M5Y E;  3FKI F;  4A3L E;  3S17 E;  4KN4 E;  3S16 E;  4BY1 F;  2VUM F;  3GTK E;  2JA5 F;  1TWF F;  1DZF A;  5BYH E;  2R93 F;  4G7Z E;  4BY7 F;  4AYB H;  5M5W E;  4C3J F;  3GTL F;  5M3F F;  4OIP E;  5D4D E;  1I6H F;  1WCM E;  4LK0 E;  4BXX F;  2KRX A;  2NVT E;  4OIO E;  3S1R F;  3M3Y F;  3H0G F;  2NVQ E;  4BBR E;  3FKI E;  4A3G F;  5E17 E;  4BY1 E;  2VUM E;  1HQM E;  3M4O F;  4A3C F;  1SFO F;  2NVT F;  4XLN E;  2R93 E;  1Y1W F;  4BY7 E;  2WAQ K;  5C4X F;  5IP9 F;  2NVQ F;  3GTL E;  3EQL E;  4XLP E;  2B63 F;  4Q4Z E;  5M3F E;  1I50 F;  1I6H E;  3HOY F;  3HKZ H; 
#chains in the Genus database with same CATH homology
 4A93 E;  4BXX E;  1EIK A;  4A3M E;  5IP7 E;  3S1R E;  1TWC E;  3M3Y E;  3H0G E;  4C3H E;  2Y0S H;  4A3G E;  5C3E E;  5C4J E;  3M4O E;  4A3C E;  1SFO E;  2YU9 E;  1Y1W E;  3HOZ E;  5C4X E;  5FLM E;  5IP9 E;  3GTO E;  2B63 E;  2WB1 H;  1I50 E;  3K7A E;  3HOY E;  3RZO E;  3I4M E;  3GTJ E;  4A3D E;  5IYD E;  1R9T E;  3S14 E;  4C2M E;  3S2H E;  5IYC E;  4A3F E;  4BBS E;  1TWA E;  5FJ8 E;  3PO3 E;  3S1N E;  2JA8 E;  1TWG E;  3HOV E;  4A3I E;  2JA7 E;  2R7Z E;  2JA6 E;  3HOU E;  4A3B E;  2NVY E;  1K83 E;  5M5X E;  3CQZ E;  1TWH E;  3GTG E;  4Y52 E;  3I4N E;  3S2D E;  3HOX E;  3PO2 E;  4X6A E;  5M3M E;  4A3J E;  4C3I E;  2WAQ H;  4A3E E;  1I3Q E;  4Y7N E;  3GTM E;  3GTP E;  3HOW E;  2R92 E;  2E2I E;  2E2H E;  3RZD E;  3S1Q E;  3S15 E;  2PMZ H;  2NVX E;  5C44 E;  4QIW H;  4A3K E;  5IYB E;  2E2J E;  3GTQ E;  2JA5 E;  1TWF E;  3S1M E;  1Y1V E;  3H3V F;  4C3J E;  5M5Y E;  4A3L E;  3S17 E;  3S16 E;  3GTK E;  1DZF A;  4AYB H;  5M5W E;  1WCM E;  2NVT E;  2NVQ E;  4BBR E;  3FKI E;  4BY1 E;  2VUM E;  2R93 E;  4BY7 E;  3GTL E;  5M3F E;  1I6H E;  3HKZ H; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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