3GTQE

Backtracked rna polymerase ii complex induced by damage
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: backtracked RNA polymerase II at 3.4 angstrom resolution.
pubmed doi rcsb
molecule tags Transcription, transferase/dna-rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 42
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3gtqE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3gtqE02
3FKIE 3RZDE 3I4NE 3I4ME 5M3FE 3GTPE 3H3VF 1TWCE 5IYBE 2E2JE 4A3EE 3S16E 4BY7E 5C4JE 3HOXE 1TWGE 2JA5E 3RZOE 2NVTE 4A3JE 2JA8E 4A3LE 3S2DE 2E2IE 4A3GE 4C3JE 2E2HE 2JA6E 1TWFE 3PO3E 4A3IE 3K7AE 4A3DE 3H0GE 4A3BE 2NVYE 4A3CE 3S17E 4A3FE 1DZFA 1I3QE 1SFOE 4BBRE 4X6AE 5IP7E 1I50E 3S1QE 5M3ME 3HOZE 1Y1VE 3GTLE 3GTJE 2WAQH 3S1RE 2B63E 3HOUE 2VUME 3CQZE 4Y7NE 2Y0SH 2YU9E 4C3IE 2NVQE 1I6HE 3HOWE 4Y52E 5C4XE 3S15E 2NVXE 1EIKA 1WCME 5FLME 1TWHE 2JA7E 1Y1WE 3S1NE 1K83E 3GTOE 3S14E 4AYBH 3GTGE 5C3EE 3M3YE 5IYCE 2R7ZE 3GTKE 4BBSE 4A93E 4A3ME 4BY1E 3GTME 4A3KE 3HOVE 3S1ME 2WB1H 5IYDE 2R92E 4C2ME 3M4OE 3S2HE 5IP9E 3HKZH 3PO2E 5M5YE 5M5XE 5C44E 5FJ8E 3HOYE 4QIWH 4BXXE 2PMZH 5M5WE 4C3HE 2R93E 1R9TE 3GTQE 1TWAE
chains in the Genus database with same CATH superfamily
3FKIE 3RZDE 3I4NE 3I4ME 5FJ8F 3HOYF 5M3FE 3GTPE 3H3VF 1TWCE 3K7AF 5IYBE 2E2JE 4A3EE 3S16E 4BY7E 5C4JE 3HOXE 1TWGE 1I6VE 4YFNE 2JA5E 3RZOE 4C3HF 5E18E 2NVTE 4A3JE 2R93F 1R9TF 2JA8E 4A3LE 4A3CF 3S2DE 3GTQF 2E2IE 4A3GE 1YNJK 4C3JE 1TWAF 5TMFE 2E2HE 2JA6E 1TWFE 3RZDF 3I4MF 5M3FF 3GTPF 4JK1E 3PO3E 4YG2E 5IYBF 4A3IE 4A3EF 3K7AE 1TWFF 4BY7F 4BBRF 4Q4ZE 5C4JF 1TWGF 4LLGE 2JA5F 4ZH4E 1I50F 4YFKE 4OINE 4A3JF 4A3DE 3RZOF 1Y1VF 2WAQK 3H0GE 3S1QF 4A3BE 2NVYE 3S2DF 4A3LF 2O5JE 4MQ9E 4A3GF 4A3CE 4C3JF 3S17E 2E2HF 2JA6F 4KN4E 4A3FE 1DZFA 1I3QE 3PO3F 3DXJE 1SFOE 2VUMF 4A3IF 4YFXE 4BBRE 4X6AE 5IP7E 4A3DF 1I50E 3S1QE 3H0GF 4A3BF 5M3ME 3HOZE 1Y1VE 3GTLE 2NVYF 4Y52F 4MEXE 4XLNE 3S17F 5E17E 3GTJE 1HQME 4A3FF 2WAQH 3S1RE 4KMUE 1I3QF 2B63E 2A68E 1WCMF 1SFOF 3HOUE 2VUME 5D4EE 3CQZE 4Y7NE 2Y0SH 4AYBK 1TWHF 4X6AF 5IP7F 2YU9E 4G7ZE 1Y1WF 4OIRE 4C3IE 2NVQE 1ZYRE 5M3MF 3GTLF 1I6HE 3HOWE 3GTOF 3HOZF 3S14F 2PPBE 4Y52E 2A69E 3GTJF 2CW0E 1YNNK 3S1RF 2A6EE 5C4XE 4XSZE 3S15E 5IYCF 2B63F 2NVXE 3GTKF 1EIKA 1WCME 3HOUF 1SMYE 2Y0SI 3CQZF 4Y7NF 5FLME 2YU9F 1TWHE 2JA7E 4OIPE 4BY1F 4C3IF 5BYHE 2NVQF 1Y1WE 1I6HF 3HOWF 3S1NE 1K83E 3GTOE 3S14E 2BE5E 4KN7E 3GTGE 4AYBH 5IPLE 5C3EE 3GTMF 5IYDF 5C4XF 3S15F 3M3YE 5IYCE 2R7ZE 3HKZK 4G7HE 2NVXF 3GTKE 5TMCE 4BBSE 4C2MF 3S2HF 5FLMF 4OIOE 4A93E 3PO2F 2JA7F 4QIWK 4A3ME 4BY1E 2PMZK 3S1NF 1K83F 3GTGF 1QKLA 4MEYE 5C3EF 4BXXF 3GTME 4A3KE 3HOVE 3S1ME 2WB1H 5IYDE 2R7ZF 5M5WF 3H3VG 3M3YF 4LJZE 4BBSF 2R92E 2A6HE 5D4CE 4C2ME 3M4OE 3EQLE 4A93F 3S2HE 5IP9E 2KRXA 4GZYE 3HKZH 3PO2E 4A3MF 5M5YE 5M5XE 3FKIF 3I4NF 4G7OE 5C44E 4LK0E 5FJ8E 3HOYE 2O5IE 1TWCF 2WB1I 4QIWH 4Q5SE 4BXXE 2E2JF 4A3KF 2PMZH 3HOVF 4LK1E 3S16F 3S1MF 3HOXF 4XLPE 1IW7E 5M5WE 4XSXE 2NVTF 4C3HE 2R92F 2JA8F 2R93E 3M4OF 1R9TE 5IP9F 4OIQE 2E2IF 3GTQE 5M5YF 5D4DE 5M5XF 1TWAE 3WODE 5C44F
chains in the Genus database with same CATH topology
3FKIE 3RZDE 3I4NE 3I4ME 5M3FE 3GTPE 3H3VF 1TWCE 5IYBE 2E2JE 4A3EE 3S16E 4BY7E 5C4JE 3HOXE 1TWGE 2JA5E 3RZOE 2NVTE 4A3JE 2JA8E 4A3LE 3S2DE 2E2IE 4A3GE 4C3JE 2E2HE 2JA6E 1TWFE 3PO3E 4A3IE 3K7AE 4A3DE 3H0GE 4A3BE 2NVYE 4A3CE 3S17E 4A3FE 1DZFA 1I3QE 1SFOE 4BBRE 4X6AE 5IP7E 1I50E 3S1QE 5M3ME 3HOZE 1Y1VE 3GTLE 3GTJE 2WAQH 3S1RE 2B63E 3HOUE 2VUME 3CQZE 4Y7NE 2Y0SH 2YU9E 4C3IE 2NVQE 1I6HE 3HOWE 4Y52E 5C4XE 3S15E 2NVXE 1EIKA 1WCME 5FLME 1TWHE 2JA7E 1Y1WE 3S1NE 1K83E 3GTOE 3S14E 4AYBH 3GTGE 5C3EE 3M3YE 5IYCE 2R7ZE 3GTKE 4BBSE 4A93E 4A3ME 4BY1E 3GTME 4A3KE 3HOVE 3S1ME 2WB1H 5IYDE 2R92E 4C2ME 3M4OE 3S2HE 5IP9E 3HKZH 3PO2E 5M5YE 5M5XE 5C44E 5FJ8E 3HOYE 4QIWH 4BXXE 2PMZH 5M5WE 4C3HE 2R93E 1R9TE 3GTQE 1TWAE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3FKI E;  3RZD E;  3I4N E;  3I4M E;  5M3F E;  3GTP E;  3H3V F;  1TWC E;  5IYB E;  2E2J E;  4A3E E;  3S16 E;  4BY7 E;  5C4J E;  3HOX E;  1TWG E;  2JA5 E;  3RZO E;  2NVT E;  4A3J E;  2JA8 E;  4A3L E;  3S2D E;  2E2I E;  4A3G E;  4C3J E;  2E2H E;  2JA6 E;  1TWF E;  3PO3 E;  4A3I E;  3K7A E;  4A3D E;  3H0G E;  4A3B E;  2NVY E;  4A3C E;  3S17 E;  4A3F E;  1DZF A;  1I3Q E;  1SFO E;  4BBR E;  4X6A E;  5IP7 E;  1I50 E;  3S1Q E;  5M3M E;  3HOZ E;  1Y1V E;  3GTL E;  3GTJ E;  2WAQ H;  3S1R E;  2B63 E;  3HOU E;  2VUM E;  3CQZ E;  4Y7N E;  2Y0S H;  2YU9 E;  4C3I E;  2NVQ E;  1I6H E;  3HOW E;  4Y52 E;  5C4X E;  3S15 E;  2NVX E;  1EIK A;  1WCM E;  5FLM E;  1TWH E;  2JA7 E;  1Y1W E;  3S1N E;  1K83 E;  3GTO E;  3S14 E;  4AYB H;  3GTG E;  5C3E E;  3M3Y E;  5IYC E;  2R7Z E;  3GTK E;  4BBS E;  4A93 E;  4A3M E;  4BY1 E;  3GTM E;  4A3K E;  3HOV E;  3S1M E;  2WB1 H;  5IYD E;  2R92 E;  4C2M E;  3M4O E;  3S2H E;  5IP9 E;  3HKZ H;  3PO2 E;  5M5Y E;  5M5X E;  5C44 E;  5FJ8 E;  3HOY E;  4QIW H;  4BXX E;  2PMZ H;  5M5W E;  4C3H E;  2R93 E;  1R9T E;  3GTQ E;  1TWA E; 
#chains in the Genus database with same CATH topology
 3FKI E;  3RZD E;  3I4N E;  3I4M E;  5FJ8 F;  3HOY F;  5M3F E;  3GTP E;  3H3V F;  1TWC E;  3K7A F;  5IYB E;  2E2J E;  4A3E E;  3S16 E;  4BY7 E;  5C4J E;  3HOX E;  1TWG E;  1I6V E;  4YFN E;  2JA5 E;  3RZO E;  4C3H F;  5E18 E;  2NVT E;  4A3J E;  2R93 F;  1R9T F;  2JA8 E;  4A3L E;  4A3C F;  3S2D E;  3GTQ F;  2E2I E;  4A3G E;  1YNJ K;  4C3J E;  1TWA F;  5TMF E;  2E2H E;  2JA6 E;  1TWF E;  3RZD F;  3I4M F;  5M3F F;  3GTP F;  4JK1 E;  3PO3 E;  4YG2 E;  5IYB F;  4A3I E;  4A3E F;  3K7A E;  1TWF F;  4BY7 F;  4BBR F;  4Q4Z E;  5C4J F;  1TWG F;  4LLG E;  2JA5 F;  4ZH4 E;  1I50 F;  4YFK E;  4OIN E;  4A3J F;  4A3D E;  3RZO F;  1Y1V F;  2WAQ K;  3H0G E;  3S1Q F;  4A3B E;  2NVY E;  3S2D F;  4A3L F;  2O5J E;  4MQ9 E;  4A3G F;  4A3C E;  4C3J F;  3S17 E;  2E2H F;  2JA6 F;  4KN4 E;  4A3F E;  1DZF A;  1I3Q E;  3PO3 F;  3DXJ E;  1SFO E;  2VUM F;  4A3I F;  4YFX E;  4BBR E;  4X6A E;  5IP7 E;  4A3D F;  1I50 E;  3S1Q E;  3H0G F;  4A3B F;  5M3M E;  3HOZ E;  1Y1V E;  3GTL E;  2NVY F;  4Y52 F;  4MEX E;  4XLN E;  3S17 F;  5E17 E;  3GTJ E;  1HQM E;  4A3F F;  2WAQ H;  3S1R E;  4KMU E;  1I3Q F;  2B63 E;  2A68 E;  1WCM F;  1SFO F;  3HOU E;  2VUM E;  5D4E E;  3CQZ E;  4Y7N E;  2Y0S H;  4AYB K;  1TWH F;  4X6A F;  5IP7 F;  2YU9 E;  4G7Z E;  1Y1W F;  4OIR E;  4C3I E;  2NVQ E;  1ZYR E;  5M3M F;  3GTL F;  1I6H E;  3HOW E;  3GTO F;  3HOZ F;  3S14 F;  2PPB E;  4Y52 E;  2A69 E;  3GTJ F;  2CW0 E;  1YNN K;  3S1R F;  2A6E E;  5C4X E;  4XSZ E;  3S15 E;  5IYC F;  2B63 F;  2NVX E;  3GTK F;  1EIK A;  1WCM E;  3HOU F;  1SMY E;  2Y0S I;  3CQZ F;  4Y7N F;  5FLM E;  2YU9 F;  1TWH E;  2JA7 E;  4OIP E;  4BY1 F;  4C3I F;  5BYH E;  2NVQ F;  1Y1W E;  1I6H F;  3HOW F;  3S1N E;  1K83 E;  3GTO E;  3S14 E;  2BE5 E;  4KN7 E;  3GTG E;  4AYB H;  5IPL E;  5C3E E;  3GTM F;  5IYD F;  5C4X F;  3S15 F;  3M3Y E;  5IYC E;  2R7Z E;  3HKZ K;  4G7H E;  2NVX F;  3GTK E;  5TMC E;  4BBS E;  4C2M F;  3S2H F;  5FLM F;  4OIO E;  4A93 E;  3PO2 F;  2JA7 F;  4QIW K;  4A3M E;  4BY1 E;  2PMZ K;  3S1N F;  1K83 F;  3GTG F;  1QKL A;  4MEY E;  5C3E F;  4BXX F;  3GTM E;  4A3K E;  3HOV E;  3S1M E;  2WB1 H;  5IYD E;  2R7Z F;  5M5W F;  3H3V G;  3M3Y F;  4LJZ E;  4BBS F;  2R92 E;  2A6H E;  5D4C E;  4C2M E;  3M4O E;  3EQL E;  4A93 F;  3S2H E;  5IP9 E;  2KRX A;  4GZY E;  3HKZ H;  3PO2 E;  4A3M F;  5M5Y E;  5M5X E;  3FKI F;  3I4N F;  4G7O E;  5C44 E;  4LK0 E;  5FJ8 E;  3HOY E;  2O5I E;  1TWC F;  2WB1 I;  4QIW H;  4Q5S E;  4BXX E;  2E2J F;  4A3K F;  2PMZ H;  3HOV F;  4LK1 E;  3S16 F;  3S1M F;  3HOX F;  4XLP E;  1IW7 E;  5M5W E;  4XSX E;  2NVT F;  4C3H E;  2R92 F;  2JA8 F;  2R93 E;  3M4O F;  1R9T E;  5IP9 F;  4OIQ E;  2E2I F;  3GTQ E;  5M5Y F;  5D4D E;  5M5X F;  1TWA E;  3WOD E;  5C44 F; 
#chains in the Genus database with same CATH homology
 3FKI E;  3RZD E;  3I4N E;  3I4M E;  5M3F E;  3GTP E;  3H3V F;  1TWC E;  5IYB E;  2E2J E;  4A3E E;  3S16 E;  4BY7 E;  5C4J E;  3HOX E;  1TWG E;  2JA5 E;  3RZO E;  2NVT E;  4A3J E;  2JA8 E;  4A3L E;  3S2D E;  2E2I E;  4A3G E;  4C3J E;  2E2H E;  2JA6 E;  1TWF E;  3PO3 E;  4A3I E;  3K7A E;  4A3D E;  3H0G E;  4A3B E;  2NVY E;  4A3C E;  3S17 E;  4A3F E;  1DZF A;  1I3Q E;  1SFO E;  4BBR E;  4X6A E;  5IP7 E;  1I50 E;  3S1Q E;  5M3M E;  3HOZ E;  1Y1V E;  3GTL E;  3GTJ E;  2WAQ H;  3S1R E;  2B63 E;  3HOU E;  2VUM E;  3CQZ E;  4Y7N E;  2Y0S H;  2YU9 E;  4C3I E;  2NVQ E;  1I6H E;  3HOW E;  4Y52 E;  5C4X E;  3S15 E;  2NVX E;  1EIK A;  1WCM E;  5FLM E;  1TWH E;  2JA7 E;  1Y1W E;  3S1N E;  1K83 E;  3GTO E;  3S14 E;  4AYB H;  3GTG E;  5C3E E;  3M3Y E;  5IYC E;  2R7Z E;  3GTK E;  4BBS E;  4A93 E;  4A3M E;  4BY1 E;  3GTM E;  4A3K E;  3HOV E;  3S1M E;  2WB1 H;  5IYD E;  2R92 E;  4C2M E;  3M4O E;  3S2H E;  5IP9 E;  3HKZ H;  3PO2 E;  5M5Y E;  5M5X E;  5C44 E;  5FJ8 E;  3HOY E;  4QIW H;  4BXX E;  2PMZ H;  5M5W E;  4C3H E;  2R93 E;  1R9T E;  3GTQ E;  1TWA E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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