3HOXE

Complete rna polymerase ii elongation complex v
Total Genus 53
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
53
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 53
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3hoxE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3hoxE02
4A3KE 2WAQH 5C3EE 4A93E 2NVTE 1TWAE 4Y52E 4A3CE 2NVYE 5C44E 3S1NE 3K7AE 4QIWH 1TWFE 4BBSE 3H3VF 4A3ME 4BY7E 5IYDE 2YU9E 3I4NE 3S16E 3GTOE 2NVQE 5M5XE 3CQZE 2R92E 3FKIE 1DZFA 3GTJE 4AYBH 3S1RE 2NVXE 3S14E 4A3FE 5FJ8E 4X6AE 3GTME 1I6HE 1TWGE 3GTPE 3GTQE 3HOYE 2B63E 4A3LE 5M5WE 4Y7NE 2E2HE 4C3JE 2E2JE 3S1QE 5FLME 1I3QE 2Y0SH 5IYCE 1SFOE 4A3DE 3S1ME 4A3IE 3HOXE 5C4XE 5M5YE 2JA8E 5IP9E 3S2HE 3PO2E 4A3JE 4C3IE 4C3HE 1WCME 3PO3E 2E2IE 3S15E 2PMZH 4BBRE 2JA5E 1Y1VE 1TWCE 4A3GE 1R9TE 2VUME 3GTGE 3S2DE 4C2ME 1K83E 3HOUE 1I50E 2JA7E 4A3EE 3M4OE 5C4JE 3H0GE 4BY1E 3M3YE 4A3BE 1TWHE 5IP7E 3S17E 3HOVE 3HKZH 1EIKA 5IYBE 3HOZE 3GTKE 2R7ZE 1Y1WE 3GTLE 3HOWE 3RZDE 5M3FE 2WB1H 3I4ME 5M3ME 2JA6E 4BXXE 3RZOE 2R93E
chains in the Genus database with same CATH superfamily
4G7OE 2E2HF 4A3KE 5E18E 4LK0E 2WAQH 4Q5SE 4MQ9E 3S1QF 5C3EE 4A93E 5IYCF 1HQME 1SFOF 3GTGF 2NVTE 1TWAE 4A3IF 3S2DF 4A3DF 5BYHE 4Y52E 4G7ZE 5C4XF 4A3EF 4A3CE 5TMFE 1SMYE 2NVYE 5C44E 3S1NE 3K7AE 4QIWH 1TWFE 4OIPE 4BBSE 4BY1F 5M5YF 2O5JE 3H3VF 4A3ME 2A6HE 4YFXE 3WODE 3S17F 3HOVF 3S2HF 3PO2F 4BY7E 4A3JF 5IYDE 3HOZF 3DXJE 2WB1I 2YU9E 3I4NE 3S16E 1ZYRE 4C3HF 3GTOE 1WCMF 2NVQE 5M5XE 3PO3F 3CQZE 2R92E 2PPBE 3FKIE 3S15F 5IPLE 4BBRF 4GZYE 2JA5F 3I4MF 1DZFA 1Y1VF 3GTJE 3HKZK 2JA6F 3S16F 4AYBH 3S1RE 2NVXE 3S14E 4A3FE 4OIQE 1TWCF 4A3GF 5FJ8E 1I6VE 1R9TF 2VUMF 2PMZK 4X6AE 3GTME 4C2MF 1I6HE 1TWGE 1K83F 5D4EE 3GTPE 3HOUF 3GTQE 1I50F 5C3EF 5D4DE 2JA7F 3M4OF 3HOYE 4A93F 2B63E 5C4JF 4A3LE 3H0GF 3M3YF 4Y52F 5M5WE 4YFKE 4A3BF 4Y7NE 1TWHF 3H3VG 5IP7F 4XSXE 4OIRE 4A3CF 3K7AF 4JK1E 2E2HE 5IYBF 4BBSF 3GTKF 4C3JE 2R7ZF 1Y1WF 2E2JE 3S1QE 3GTLF 3HOWF 5FLME 1I3QE 2Y0SH 5IYCE 2BE5E 1SFOE 4A3DE 4XSZE 3S1ME 4A3IE 5M3FF 4QIWK 3HOXE 5M3MF 3RZDF 4LLGE 3GTOF 2R92F 4BXXF 5C4XE 1YNNK 3FKIF 2A68E 4MEXE 3RZOF 5M5YE 2R93F 5E17E 2JA8E 5IP9E 4KN4E 4A3KF 4A3FF 3S2HE 3PO2E 4A3JE 2A6EE 4XLNE 4C3IE 4C3HE 5TMCE 1WCME 3PO3E 2E2IE 1TWAF 2NVTF 4OINE 3S15E 2PMZH 4AYBK 4BBRE 2A69E 2CW0E 2JA5E 1IW7E 4KMUE 3GTPF 3GTQF 3HOYF 2NVYF 1Y1VE 2WAQK 5C44F 2O5IE 1TWFF 3S1NF 4A3LF 4KN7E 4ZH4E 1YNJK 4A3MF 1TWCE 4A3GE 4Q4ZE 2Y0SI 4BY7F 1R9TE 2VUME 5IYDF 2YU9F 3GTGE 4C3JF 3S2DE 4C2ME 4OIOE 1K83E 4LJZE 2E2JF 2NVQF 5M5XF 3CQZF 3HOUE 1I50E 1I3QF 2JA7E 4A3EE 3M4OE 4LK1E 1QKLA 4MEYE 5FLMF 5C4JE 3H0GE 3S1MF 4BY1E 4Y7NF 3M3YE 3HOXF 3GTJF 4A3BE 1TWHE 3S1RF 5IP7E 3S17E 3EQLE 3HOVE 2NVXF 3S14F 3HKZH 1EIKA 5IYBE 3HOZE 2KRXA 5FJ8F 3GTKE 2JA8F 2R7ZE 5IP9F 4X6AF 1Y1WE 3GTMF 3I4NF 3GTLE 3HOWE 1TWGF 1I6HF 4C3IF 4YFNE 5D4CE 3RZDE 5M3FE 2WB1H 3I4ME 5M3ME 2B63F 2E2IF 2JA6E 4BXXE 4G7HE 5M5WF 3RZOE 4YG2E 2R93E 4XLPE
chains in the Genus database with same CATH topology
4A3KE 2WAQH 5C3EE 4A93E 2NVTE 1TWAE 4Y52E 4A3CE 2NVYE 5C44E 3S1NE 3K7AE 4QIWH 1TWFE 4BBSE 3H3VF 4A3ME 4BY7E 5IYDE 2YU9E 3I4NE 3S16E 3GTOE 2NVQE 5M5XE 3CQZE 2R92E 3FKIE 1DZFA 3GTJE 4AYBH 3S1RE 2NVXE 3S14E 4A3FE 5FJ8E 4X6AE 3GTME 1I6HE 1TWGE 3GTPE 3GTQE 3HOYE 2B63E 4A3LE 5M5WE 4Y7NE 2E2HE 4C3JE 2E2JE 3S1QE 5FLME 1I3QE 2Y0SH 5IYCE 1SFOE 4A3DE 3S1ME 4A3IE 3HOXE 5C4XE 5M5YE 2JA8E 5IP9E 3S2HE 3PO2E 4A3JE 4C3IE 4C3HE 1WCME 3PO3E 2E2IE 3S15E 2PMZH 4BBRE 2JA5E 1Y1VE 1TWCE 4A3GE 1R9TE 2VUME 3GTGE 3S2DE 4C2ME 1K83E 3HOUE 1I50E 2JA7E 4A3EE 3M4OE 5C4JE 3H0GE 4BY1E 3M3YE 4A3BE 1TWHE 5IP7E 3S17E 3HOVE 3HKZH 1EIKA 5IYBE 3HOZE 3GTKE 2R7ZE 1Y1WE 3GTLE 3HOWE 3RZDE 5M3FE 2WB1H 3I4ME 5M3ME 2JA6E 4BXXE 3RZOE 2R93E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3K E;  2WAQ H;  5C3E E;  4A93 E;  2NVT E;  1TWA E;  4Y52 E;  4A3C E;  2NVY E;  5C44 E;  3S1N E;  3K7A E;  4QIW H;  1TWF E;  4BBS E;  3H3V F;  4A3M E;  4BY7 E;  5IYD E;  2YU9 E;  3I4N E;  3S16 E;  3GTO E;  2NVQ E;  5M5X E;  3CQZ E;  2R92 E;  3FKI E;  1DZF A;  3GTJ E;  4AYB H;  3S1R E;  2NVX E;  3S14 E;  4A3F E;  5FJ8 E;  4X6A E;  3GTM E;  1I6H E;  1TWG E;  3GTP E;  3GTQ E;  3HOY E;  2B63 E;  4A3L E;  5M5W E;  4Y7N E;  2E2H E;  4C3J E;  2E2J E;  3S1Q E;  5FLM E;  1I3Q E;  2Y0S H;  5IYC E;  1SFO E;  4A3D E;  3S1M E;  4A3I E;  3HOX E;  5C4X E;  5M5Y E;  2JA8 E;  5IP9 E;  3S2H E;  3PO2 E;  4A3J E;  4C3I E;  4C3H E;  1WCM E;  3PO3 E;  2E2I E;  3S15 E;  2PMZ H;  4BBR E;  2JA5 E;  1Y1V E;  1TWC E;  4A3G E;  1R9T E;  2VUM E;  3GTG E;  3S2D E;  4C2M E;  1K83 E;  3HOU E;  1I50 E;  2JA7 E;  4A3E E;  3M4O E;  5C4J E;  3H0G E;  4BY1 E;  3M3Y E;  4A3B E;  1TWH E;  5IP7 E;  3S17 E;  3HOV E;  3HKZ H;  1EIK A;  5IYB E;  3HOZ E;  3GTK E;  2R7Z E;  1Y1W E;  3GTL E;  3HOW E;  3RZD E;  5M3F E;  2WB1 H;  3I4M E;  5M3M E;  2JA6 E;  4BXX E;  3RZO E;  2R93 E; 
#chains in the Genus database with same CATH topology
 4G7O E;  2E2H F;  4A3K E;  5E18 E;  4LK0 E;  2WAQ H;  4Q5S E;  4MQ9 E;  3S1Q F;  5C3E E;  4A93 E;  5IYC F;  1HQM E;  1SFO F;  3GTG F;  2NVT E;  1TWA E;  4A3I F;  3S2D F;  4A3D F;  5BYH E;  4Y52 E;  4G7Z E;  5C4X F;  4A3E F;  4A3C E;  5TMF E;  1SMY E;  2NVY E;  5C44 E;  3S1N E;  3K7A E;  4QIW H;  1TWF E;  4OIP E;  4BBS E;  4BY1 F;  5M5Y F;  2O5J E;  3H3V F;  4A3M E;  2A6H E;  4YFX E;  3WOD E;  3S17 F;  3HOV F;  3S2H F;  3PO2 F;  4BY7 E;  4A3J F;  5IYD E;  3HOZ F;  3DXJ E;  2WB1 I;  2YU9 E;  3I4N E;  3S16 E;  1ZYR E;  4C3H F;  3GTO E;  1WCM F;  2NVQ E;  5M5X E;  3PO3 F;  3CQZ E;  2R92 E;  2PPB E;  3FKI E;  3S15 F;  5IPL E;  4BBR F;  4GZY E;  2JA5 F;  3I4M F;  1DZF A;  1Y1V F;  3GTJ E;  3HKZ K;  2JA6 F;  3S16 F;  4AYB H;  3S1R E;  2NVX E;  3S14 E;  4A3F E;  4OIQ E;  1TWC F;  4A3G F;  5FJ8 E;  1I6V E;  1R9T F;  2VUM F;  2PMZ K;  4X6A E;  3GTM E;  4C2M F;  1I6H E;  1TWG E;  1K83 F;  5D4E E;  3GTP E;  3HOU F;  3GTQ E;  1I50 F;  5C3E F;  5D4D E;  2JA7 F;  3M4O F;  3HOY E;  4A93 F;  2B63 E;  5C4J F;  4A3L E;  3H0G F;  3M3Y F;  4Y52 F;  5M5W E;  4YFK E;  4A3B F;  4Y7N E;  1TWH F;  3H3V G;  5IP7 F;  4XSX E;  4OIR E;  4A3C F;  3K7A F;  4JK1 E;  2E2H E;  5IYB F;  4BBS F;  3GTK F;  4C3J E;  2R7Z F;  1Y1W F;  2E2J E;  3S1Q E;  3GTL F;  3HOW F;  5FLM E;  1I3Q E;  2Y0S H;  5IYC E;  2BE5 E;  1SFO E;  4A3D E;  4XSZ E;  3S1M E;  4A3I E;  5M3F F;  4QIW K;  3HOX E;  5M3M F;  3RZD F;  4LLG E;  3GTO F;  2R92 F;  4BXX F;  5C4X E;  1YNN K;  3FKI F;  2A68 E;  4MEX E;  3RZO F;  5M5Y E;  2R93 F;  5E17 E;  2JA8 E;  5IP9 E;  4KN4 E;  4A3K F;  4A3F F;  3S2H E;  3PO2 E;  4A3J E;  2A6E E;  4XLN E;  4C3I E;  4C3H E;  5TMC E;  1WCM E;  3PO3 E;  2E2I E;  1TWA F;  2NVT F;  4OIN E;  3S15 E;  2PMZ H;  4AYB K;  4BBR E;  2A69 E;  2CW0 E;  2JA5 E;  1IW7 E;  4KMU E;  3GTP F;  3GTQ F;  3HOY F;  2NVY F;  1Y1V E;  2WAQ K;  5C44 F;  2O5I E;  1TWF F;  3S1N F;  4A3L F;  4KN7 E;  4ZH4 E;  1YNJ K;  4A3M F;  1TWC E;  4A3G E;  4Q4Z E;  2Y0S I;  4BY7 F;  1R9T E;  2VUM E;  5IYD F;  2YU9 F;  3GTG E;  4C3J F;  3S2D E;  4C2M E;  4OIO E;  1K83 E;  4LJZ E;  2E2J F;  2NVQ F;  5M5X F;  3CQZ F;  3HOU E;  1I50 E;  1I3Q F;  2JA7 E;  4A3E E;  3M4O E;  4LK1 E;  1QKL A;  4MEY E;  5FLM F;  5C4J E;  3H0G E;  3S1M F;  4BY1 E;  4Y7N F;  3M3Y E;  3HOX F;  3GTJ F;  4A3B E;  1TWH E;  3S1R F;  5IP7 E;  3S17 E;  3EQL E;  3HOV E;  2NVX F;  3S14 F;  3HKZ H;  1EIK A;  5IYB E;  3HOZ E;  2KRX A;  5FJ8 F;  3GTK E;  2JA8 F;  2R7Z E;  5IP9 F;  4X6A F;  1Y1W E;  3GTM F;  3I4N F;  3GTL E;  3HOW E;  1TWG F;  1I6H F;  4C3I F;  4YFN E;  5D4C E;  3RZD E;  5M3F E;  2WB1 H;  3I4M E;  5M3M E;  2B63 F;  2E2I F;  2JA6 E;  4BXX E;  4G7H E;  5M5W F;  3RZO E;  4YG2 E;  2R93 E;  4XLP E; 
#chains in the Genus database with same CATH homology
 4A3K E;  2WAQ H;  5C3E E;  4A93 E;  2NVT E;  1TWA E;  4Y52 E;  4A3C E;  2NVY E;  5C44 E;  3S1N E;  3K7A E;  4QIW H;  1TWF E;  4BBS E;  3H3V F;  4A3M E;  4BY7 E;  5IYD E;  2YU9 E;  3I4N E;  3S16 E;  3GTO E;  2NVQ E;  5M5X E;  3CQZ E;  2R92 E;  3FKI E;  1DZF A;  3GTJ E;  4AYB H;  3S1R E;  2NVX E;  3S14 E;  4A3F E;  5FJ8 E;  4X6A E;  3GTM E;  1I6H E;  1TWG E;  3GTP E;  3GTQ E;  3HOY E;  2B63 E;  4A3L E;  5M5W E;  4Y7N E;  2E2H E;  4C3J E;  2E2J E;  3S1Q E;  5FLM E;  1I3Q E;  2Y0S H;  5IYC E;  1SFO E;  4A3D E;  3S1M E;  4A3I E;  3HOX E;  5C4X E;  5M5Y E;  2JA8 E;  5IP9 E;  3S2H E;  3PO2 E;  4A3J E;  4C3I E;  4C3H E;  1WCM E;  3PO3 E;  2E2I E;  3S15 E;  2PMZ H;  4BBR E;  2JA5 E;  1Y1V E;  1TWC E;  4A3G E;  1R9T E;  2VUM E;  3GTG E;  3S2D E;  4C2M E;  1K83 E;  3HOU E;  1I50 E;  2JA7 E;  4A3E E;  3M4O E;  5C4J E;  3H0G E;  4BY1 E;  3M3Y E;  4A3B E;  1TWH E;  5IP7 E;  3S17 E;  3HOV E;  3HKZ H;  1EIK A;  5IYB E;  3HOZ E;  3GTK E;  2R7Z E;  1Y1W E;  3GTL E;  3HOW E;  3RZD E;  5M3F E;  2WB1 H;  3I4M E;  5M3M E;  2JA6 E;  4BXX E;  3RZO E;  2R93 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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