3HOYE

Complete rna polymerase ii elongation complex vi
Total Genus 57
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
57
sequence length
213
structure length
213
Chain Sequence
QENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 57
structure length 213
sequence length 213
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3hoyE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3hoyE02
5IYDE 4C3JE 1I6HE 1SFOE 4BY1E 4A3JE 2WAQH 2JA8E 3PO3E 2E2IE 3K7AE 4A3KE 3GTQE 4Y7NE 4C3IE 4A3CE 4C3HE 5M5WE 2NVTE 2VUME 1Y1WE 3S14E 5C44E 3HOVE 1WCME 2R92E 3S1QE 2JA7E 2R93E 3S15E 4A3EE 2NVYE 1I3QE 3S1ME 5C4JE 3S2HE 3HOXE 3H3VF 4A3ME 4A3FE 2JA6E 3GTJE 1DZFA 1TWHE 5M3ME 3PO2E 3GTKE 1TWGE 3HOUE 4QIWH 3S1NE 5FJ8E 3FKIE 4A3BE 1K83E 5IP9E 2NVQE 1TWCE 3S16E 5M5YE 5C4XE 4A93E 3HOYE 3M3YE 3GTLE 2YU9E 5M3FE 3S1RE 1EIKA 3I4NE 2R7ZE 3GTGE 3HOWE 3HOZE 2Y0SH 3HKZH 3H0GE 5IYCE 4BBRE 3CQZE 1Y1VE 4BXXE 4A3IE 4BBSE 3GTME 5M5XE 4Y52E 5IP7E 1R9TE 1TWAE 4BY7E 1I50E 5C3EE 4A3DE 2E2JE 3M4OE 3S17E 3RZOE 3GTOE 2B63E 2E2HE 2PMZH 2JA5E 5IYBE 4A3GE 4X6AE 1TWFE 3RZDE 4AYBH 3S2DE 2WB1H 2NVXE 3I4ME 4C2ME 5FLME 3GTPE 4A3LE
chains in the Genus database with same CATH superfamily
5IYDE 3M4OF 4C3JE 1I6HE 3S17F 1SFOE 4BY1E 2KRXA 4A3JE 3GTOF 2BE5E 2WAQH 5BYHE 2CW0E 2E2HF 2JA8E 3PO3E 2B63F 2E2IE 3K7AE 4A3KE 3GTQE 4Y7NE 4C3IE 5IYBF 2JA5F 4A3GF 4X6AF 1TWFF 2WAQK 4A3CE 3RZDF 4C3HE 5M5WE 2NVTE 1ZYRE 3S2DF 2VUME 3I4MF 2Y0SI 1Y1WE 4Q5SE 1QKLA 3S14E 4C2MF 5FLMF 4OIQE 5C44E 2PPBE 3HOVE 4G7HE 4YFXE 1WCME 2R92E 2E2JF 3GTPF 4G7ZE 3S1QE 2JA7E 4A3LF 2R93E 1SMYE 4C3JF 3S15E 4A3EE 1I6HF 2NVYE 4BY1F 1SFOF 1I3QE 3S1ME 5C4JE 3S2HE 5C3EF 4A3JF 2A69E 3HOXE 3H3VF 4GZYE 1I6VE 4A3ME 2JA8F 4XSXE 3PO3F 3K7AF 4A3FE 2JA6E 4Y7NF 3GTJE 4KN4E 4C3IF 4A3KF 5E18E 4KN7E 4YG2E 3RZOF 3HKZK 4A3CF 4OIRE 5TMCE 4MEYE 1DZFA 1TWHE 4C3HF 5M3ME 3PO2E 5M5WF 2NVTF 2VUMF 3GTKE 1TWGE 3HOUE 4QIWH 3S1NE 1Y1WF 4MEXE 3S14F 5FJ8E 5C44F 3FKIE 4A3BE 1K83E 5IP9E 2NVQE 2NVXF 1TWCE 4ZH4E 2R92F 3S16E 3EQLE 5M5YE 4QIWK 3S1QF 5C4XE 2JA7F 2R93F 3WODE 3S15F 2NVYF 2A6HE 1I3QF 3S1MF 4A93E 3HOYE 3S2HF 5E17E 5IYDF 3M3YE 3HOXF 4G7OE 4A3MF 3GTLE 2YU9E 5M3FE 3S1RE 4XSZE 3I4NE 2R7ZE 3GTGE 3GTJF 4A3FF 2WB1I 3HOWE 4LJZE 3HOZE 4XLNE 3GTQF 2Y0SH 3HKZH 3H0GE 4LK0E 4YFNE 1TWHF 5IYCE 1YNJK 4OIPE 5M3MF 2E2IF 3PO2F 3GTKF 1TWGF 3HOUF 4Q4ZE 3S1NF 5FJ8F 4BBRE 1YNNK 4MQ9E 1HQME 3CQZE 3FKIF 4A3BF 5IP9F 1Y1VE 2NVQF 1TWCF 4BXXE 3DXJE 5M5YF 5C4XF 3HOVF 5D4DE 1WCMF 4A93F 3HOYF 4LLGE 4A3IE 4BBSE 3M3YF 4A3EF 4OINE 2A68E 5D4EE 3GTME 3GTLF 2YU9F 5M3FF 5C4JF 5M5XE 3S1RF 3I4NF 4Y52E 3GTGF 2R7ZF 5IP7E 4OIOE 1R9TE 3HOZF 1TWAE 4BY7E 3H0GF 1I50E 5C3EE 4A3DE 5IYCF 2O5IE 2E2JE 1IW7E 2A6EE 3M4OE 2O5JE 4KMUE 3S17E 4BBRF 2JA6F 3CQZF 1Y1VF 5D4CE 4BXXF 4YFKE 3RZOE 3GTOE 2B63E 2E2HE 2PMZH 4JK1E 1K83F 2JA5E 5IYBE 4A3GE 4X6AE 5IPLE 3S16F 4A3IF 1TWFE 2PMZK 3RZDE 4BBSF 4AYBH 3S2DE 2WB1H 2NVXE 5TMFE 3GTMF 3I4ME 4LK1E 5M5XF 4Y52F 4C2ME 5IP7F 5FLME 1R9TF 3H3VG 1TWAF 4AYBK 4BY7F 1I50F 4XLPE 4A3DF 1EIKA 3GTPE 4A3LE 3HOWF
chains in the Genus database with same CATH topology
5IYDE 4C3JE 1I6HE 1SFOE 4BY1E 4A3JE 2WAQH 2JA8E 3PO3E 2E2IE 3K7AE 4A3KE 3GTQE 4Y7NE 4C3IE 4A3CE 4C3HE 5M5WE 2NVTE 2VUME 1Y1WE 3S14E 5C44E 3HOVE 1WCME 2R92E 3S1QE 2JA7E 2R93E 3S15E 4A3EE 2NVYE 1I3QE 3S1ME 5C4JE 3S2HE 3HOXE 3H3VF 4A3ME 4A3FE 2JA6E 3GTJE 1DZFA 1TWHE 5M3ME 3PO2E 3GTKE 1TWGE 3HOUE 4QIWH 3S1NE 5FJ8E 3FKIE 4A3BE 1K83E 5IP9E 2NVQE 1TWCE 3S16E 5M5YE 5C4XE 4A93E 3HOYE 3M3YE 3GTLE 2YU9E 5M3FE 3S1RE 1EIKA 3I4NE 2R7ZE 3GTGE 3HOWE 3HOZE 2Y0SH 3HKZH 3H0GE 5IYCE 4BBRE 3CQZE 1Y1VE 4BXXE 4A3IE 4BBSE 3GTME 5M5XE 4Y52E 5IP7E 1R9TE 1TWAE 4BY7E 1I50E 5C3EE 4A3DE 2E2JE 3M4OE 3S17E 3RZOE 3GTOE 2B63E 2E2HE 2PMZH 2JA5E 5IYBE 4A3GE 4X6AE 1TWFE 3RZDE 4AYBH 3S2DE 2WB1H 2NVXE 3I4ME 4C2ME 5FLME 3GTPE 4A3LE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5IYD E;  4C3J E;  1I6H E;  1SFO E;  4BY1 E;  4A3J E;  2WAQ H;  2JA8 E;  3PO3 E;  2E2I E;  3K7A E;  4A3K E;  3GTQ E;  4Y7N E;  4C3I E;  4A3C E;  4C3H E;  5M5W E;  2NVT E;  2VUM E;  1Y1W E;  3S14 E;  5C44 E;  3HOV E;  1WCM E;  2R92 E;  3S1Q E;  2JA7 E;  2R93 E;  3S15 E;  4A3E E;  2NVY E;  1I3Q E;  3S1M E;  5C4J E;  3S2H E;  3HOX E;  3H3V F;  4A3M E;  4A3F E;  2JA6 E;  3GTJ E;  1DZF A;  1TWH E;  5M3M E;  3PO2 E;  3GTK E;  1TWG E;  3HOU E;  4QIW H;  3S1N E;  5FJ8 E;  3FKI E;  4A3B E;  1K83 E;  5IP9 E;  2NVQ E;  1TWC E;  3S16 E;  5M5Y E;  5C4X E;  4A93 E;  3HOY E;  3M3Y E;  3GTL E;  2YU9 E;  5M3F E;  3S1R E;  1EIK A;  3I4N E;  2R7Z E;  3GTG E;  3HOW E;  3HOZ E;  2Y0S H;  3HKZ H;  3H0G E;  5IYC E;  4BBR E;  3CQZ E;  1Y1V E;  4BXX E;  4A3I E;  4BBS E;  3GTM E;  5M5X E;  4Y52 E;  5IP7 E;  1R9T E;  1TWA E;  4BY7 E;  1I50 E;  5C3E E;  4A3D E;  2E2J E;  3M4O E;  3S17 E;  3RZO E;  3GTO E;  2B63 E;  2E2H E;  2PMZ H;  2JA5 E;  5IYB E;  4A3G E;  4X6A E;  1TWF E;  3RZD E;  4AYB H;  3S2D E;  2WB1 H;  2NVX E;  3I4M E;  4C2M E;  5FLM E;  3GTP E;  4A3L E; 
#chains in the Genus database with same CATH topology
 5IYD E;  3M4O F;  4C3J E;  1I6H E;  3S17 F;  1SFO E;  4BY1 E;  2KRX A;  4A3J E;  3GTO F;  2BE5 E;  2WAQ H;  5BYH E;  2CW0 E;  2E2H F;  2JA8 E;  3PO3 E;  2B63 F;  2E2I E;  3K7A E;  4A3K E;  3GTQ E;  4Y7N E;  4C3I E;  5IYB F;  2JA5 F;  4A3G F;  4X6A F;  1TWF F;  2WAQ K;  4A3C E;  3RZD F;  4C3H E;  5M5W E;  2NVT E;  1ZYR E;  3S2D F;  2VUM E;  3I4M F;  2Y0S I;  1Y1W E;  4Q5S E;  1QKL A;  3S14 E;  4C2M F;  5FLM F;  4OIQ E;  5C44 E;  2PPB E;  3HOV E;  4G7H E;  4YFX E;  1WCM E;  2R92 E;  2E2J F;  3GTP F;  4G7Z E;  3S1Q E;  2JA7 E;  4A3L F;  2R93 E;  1SMY E;  4C3J F;  3S15 E;  4A3E E;  1I6H F;  2NVY E;  4BY1 F;  1SFO F;  1I3Q E;  3S1M E;  5C4J E;  3S2H E;  5C3E F;  4A3J F;  2A69 E;  3HOX E;  3H3V F;  4GZY E;  1I6V E;  4A3M E;  2JA8 F;  4XSX E;  3PO3 F;  3K7A F;  4A3F E;  2JA6 E;  4Y7N F;  3GTJ E;  4KN4 E;  4C3I F;  4A3K F;  5E18 E;  4KN7 E;  4YG2 E;  3RZO F;  3HKZ K;  4A3C F;  4OIR E;  5TMC E;  4MEY E;  1DZF A;  1TWH E;  4C3H F;  5M3M E;  3PO2 E;  5M5W F;  2NVT F;  2VUM F;  3GTK E;  1TWG E;  3HOU E;  4QIW H;  3S1N E;  1Y1W F;  4MEX E;  3S14 F;  5FJ8 E;  5C44 F;  3FKI E;  4A3B E;  1K83 E;  5IP9 E;  2NVQ E;  2NVX F;  1TWC E;  4ZH4 E;  2R92 F;  3S16 E;  3EQL E;  5M5Y E;  4QIW K;  3S1Q F;  5C4X E;  2JA7 F;  2R93 F;  3WOD E;  3S15 F;  2NVY F;  2A6H E;  1I3Q F;  3S1M F;  4A93 E;  3HOY E;  3S2H F;  5E17 E;  5IYD F;  3M3Y E;  3HOX F;  4G7O E;  4A3M F;  3GTL E;  2YU9 E;  5M3F E;  3S1R E;  4XSZ E;  3I4N E;  2R7Z E;  3GTG E;  3GTJ F;  4A3F F;  2WB1 I;  3HOW E;  4LJZ E;  3HOZ E;  4XLN E;  3GTQ F;  2Y0S H;  3HKZ H;  3H0G E;  4LK0 E;  4YFN E;  1TWH F;  5IYC E;  1YNJ K;  4OIP E;  5M3M F;  2E2I F;  3PO2 F;  3GTK F;  1TWG F;  3HOU F;  4Q4Z E;  3S1N F;  5FJ8 F;  4BBR E;  1YNN K;  4MQ9 E;  1HQM E;  3CQZ E;  3FKI F;  4A3B F;  5IP9 F;  1Y1V E;  2NVQ F;  1TWC F;  4BXX E;  3DXJ E;  5M5Y F;  5C4X F;  3HOV F;  5D4D E;  1WCM F;  4A93 F;  3HOY F;  4LLG E;  4A3I E;  4BBS E;  3M3Y F;  4A3E F;  4OIN E;  2A68 E;  5D4E E;  3GTM E;  3GTL F;  2YU9 F;  5M3F F;  5C4J F;  5M5X E;  3S1R F;  3I4N F;  4Y52 E;  3GTG F;  2R7Z F;  5IP7 E;  4OIO E;  1R9T E;  3HOZ F;  1TWA E;  4BY7 E;  3H0G F;  1I50 E;  5C3E E;  4A3D E;  5IYC F;  2O5I E;  2E2J E;  1IW7 E;  2A6E E;  3M4O E;  2O5J E;  4KMU E;  3S17 E;  4BBR F;  2JA6 F;  3CQZ F;  1Y1V F;  5D4C E;  4BXX F;  4YFK E;  3RZO E;  3GTO E;  2B63 E;  2E2H E;  2PMZ H;  4JK1 E;  1K83 F;  2JA5 E;  5IYB E;  4A3G E;  4X6A E;  5IPL E;  3S16 F;  4A3I F;  1TWF E;  2PMZ K;  3RZD E;  4BBS F;  4AYB H;  3S2D E;  2WB1 H;  2NVX E;  5TMF E;  3GTM F;  3I4M E;  4LK1 E;  5M5X F;  4Y52 F;  4C2M E;  5IP7 F;  5FLM E;  1R9T F;  3H3V G;  1TWA F;  4AYB K;  4BY7 F;  1I50 F;  4XLP E;  4A3D F;  1EIK A;  3GTP E;  4A3L E;  3HOW F; 
#chains in the Genus database with same CATH homology
 5IYD E;  4C3J E;  1I6H E;  1SFO E;  4BY1 E;  4A3J E;  2WAQ H;  2JA8 E;  3PO3 E;  2E2I E;  3K7A E;  4A3K E;  3GTQ E;  4Y7N E;  4C3I E;  4A3C E;  4C3H E;  5M5W E;  2NVT E;  2VUM E;  1Y1W E;  3S14 E;  5C44 E;  3HOV E;  1WCM E;  2R92 E;  3S1Q E;  2JA7 E;  2R93 E;  3S15 E;  4A3E E;  2NVY E;  1I3Q E;  3S1M E;  5C4J E;  3S2H E;  3HOX E;  3H3V F;  4A3M E;  4A3F E;  2JA6 E;  3GTJ E;  1DZF A;  1TWH E;  5M3M E;  3PO2 E;  3GTK E;  1TWG E;  3HOU E;  4QIW H;  3S1N E;  5FJ8 E;  3FKI E;  4A3B E;  1K83 E;  5IP9 E;  2NVQ E;  1TWC E;  3S16 E;  5M5Y E;  5C4X E;  4A93 E;  3HOY E;  3M3Y E;  3GTL E;  2YU9 E;  5M3F E;  3S1R E;  1EIK A;  3I4N E;  2R7Z E;  3GTG E;  3HOW E;  3HOZ E;  2Y0S H;  3HKZ H;  3H0G E;  5IYC E;  4BBR E;  3CQZ E;  1Y1V E;  4BXX E;  4A3I E;  4BBS E;  3GTM E;  5M5X E;  4Y52 E;  5IP7 E;  1R9T E;  1TWA E;  4BY7 E;  1I50 E;  5C3E E;  4A3D E;  2E2J E;  3M4O E;  3S17 E;  3RZO E;  3GTO E;  2B63 E;  2E2H E;  2PMZ H;  2JA5 E;  5IYB E;  4A3G E;  4X6A E;  1TWF E;  3RZD E;  4AYB H;  3S2D E;  2WB1 H;  2NVX E;  3I4M E;  4C2M E;  5FLM E;  3GTP E;  4A3L E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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