3HOZE

Complete rna polymerase ii elongation complex iv with a t-u mismatch and a frayed rna 3'-guanine
Total Genus 56
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
56
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural basis of transcription: mismatch-specific fidelity mechanisms and paused RNA polymerase II with frayed RNA.
pubmed doi rcsb
molecule tags Transcription,transferase/dna/rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 56
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-06-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3hozE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3hozE02
3HOWE 5M3FE 2JA6E 3I4ME 3GTGE 1EIKA 1SFOE 1TWFE 3S1RE 4X6AE 4BY1E 4A3DE 2NVYE 2R92E 4Y52E 4A3GE 3GTLE 4QIWH 2E2IE 3HOXE 2YU9E 4A3EE 2E2HE 3RZOE 5C4XE 5FLME 2PMZH 3PO2E 1I6HE 4C3IE 4A3ME 5IYBE 2WAQH 4A3IE 2JA5E 3S2DE 3S17E 3S1QE 4A3LE 3HOZE 3S2HE 4AYBH 1WCME 5C4JE 2E2JE 5IYCE 5M3ME 3H0GE 3HKZH 3S16E 4BBSE 2NVTE 2NVXE 1I50E 3GTOE 1Y1WE 3S14E 4A93E 1TWGE 3S1NE 3M4OE 3HOYE 1DZFA 4Y7NE 2B63E 4A3CE 3S1ME 5IYDE 5M5YE 3GTJE 3RZDE 3GTME 5IP7E 1TWAE 5M5WE 4C3JE 4A3KE 3GTKE 3FKIE 5M5XE 4BY7E 1I3QE 1R9TE 3S15E 4C3HE 4BXXE 1K83E 4A3JE 3M3YE 5FJ8E 5IP9E 2WB1H 3I4NE 4A3FE 2NVQE 2R7ZE 4BBRE 3GTQE 1TWCE 2R93E 1Y1VE 3K7AE 5C3EE 2VUME 4C2ME 3PO3E 1TWHE 2JA8E 5C44E 3GTPE 2Y0SH 2JA7E 3HOUE 3H3VF 3HOVE 4A3BE 3CQZE
chains in the Genus database with same CATH superfamily
3HOWE 5M3FE 1ZYRE 2JA6E 3I4ME 3GTGE 3WODE 5M5WF 1SFOE 1TWFE 5D4DE 2JA8F 1EIKA 5C44F 3S1RE 4X6AE 4BY1E 4A3DE 4BY7F 2NVYE 2R92E 2JA7F 4Y52E 4QIWK 4A3GE 1I6VE 1HQME 1R9TF 3HOUF 3HOVF 1K83F 3GTLE 4QIWH 4A3BF 5TMCE 3HOWF 5M3FF 4Q4ZE 2JA6F 3I4MF 1TWFF 2E2IE 3HOXE 2PMZK 2YU9E 4A3EE 2E2HE 3S1RF 3RZOE 4LK0E 5C4XE 5FLME 4BY1F 2PMZH 2NVYF 4MEXE 4G7OE 3PO2E 2R92F 3DXJE 2BE5E 2R93F 1Y1VF 1I6HE 4C3IE 2WAQK 4Q5SE 4A3ME 5C3EF 3M3YF 4JK1E 5IYBE 4C2MF 2WAQH 4A3IE 2JA5E 3S2DE 2E2IF 4AYBK 4YFNE 3S17E 3S1QE 4A3LE 1YNNK 4OINE 3HOZE 3S2HE 2YU9F 4AYBH 2E2HF 1WCME 5C4JE 5FLMF 5C4XF 2E2JE 3PO2F 2O5IE 4LK1E 3HKZK 5IYCE 3GTPF 5D4CE 1I6HF 5M3ME 4C3IF 3H0GE 3HKZH 4KMUE 4KN7E 5IYBF 3S16E 4BBSE 4A3IF 3CQZF 2JA5F 4A3DF 3S2DF 2NVTE 5D4EE 2NVXE 3GTGF 4A3LF 1I50E 3GTOE 2A6HE 2KRXA 1SFOF 3S2HF 1Y1WE 1WCMF 5C4JF 3S14E 4A93E 2E2JF 2O5JE 5E17E 5IPLE 1TWGE 4Y52F 3S1NE 3H0GF 5M3MF 3M4OE 3HOYE 4A3GF 3S16F 4YFXE 3GTLF 4BBSF 1DZFA 4Y7NE 2NVTF 1YNJK 2A69E 2B63E 1I50F 3GTOF 4A3CE 3S1ME 1QKLA 3HOXF 5IYDE 1Y1WF 5M5YE 3S14F 4A93F 3GTJE 4YFKE 4A3EF 3RZDE 3RZOF 4OIOE 3GTME 3EQLE 4X6AF 4MEYE 5IP7E 3M4OF 4YG2E 4XSZE 3HOYF 2CW0E 3H3VG 1IW7E 4A3MF 1TWAE 5M5WE 4C3JE 4A3KE 4Y7NF 4XSXE 3GTKE 2B63F 2WB1I 3FKIE 4A3CF 2A6EE 5M5XE 5IYDF 4OIRE 5M5YF 3S17F 3HOZF 3GTJF 4BY7E 3S1QF 1I3QE 5TMFE 4XLNE 3GTMF 1R9TE 3S15E 5E18E 4C3HE 5IYCF 4BXXE 1K83E 1SMYE 4A3JE 3M3YE 5IP7F 5FJ8E 5IP9E 2A68E 1TWHF 4KN4E 1TWAF 2WB1H 3I4NE 4A3FE 4C3JF 4A3KF 2PPBE 3PO3F 2NVQE 3GTKF 4LLGE 3FKIF 2R7ZE 4BBRE 5M5XF 2NVXF 3GTQE 4MQ9E 4XLPE 1TWCE 1I3QF 2R93E 1Y1VE 3S15F 4C3HF 3K7AE 4BXXF 5C3EE 2VUME 1TWGF 4A3JF 2Y0SI 5IP9F 5FJ8F 4C2ME 3PO3E 1TWHE 3S1NF 5BYHE 3I4NF 4A3FF 2NVQF 2JA8E 2R7ZF 4BBRF 3GTQF 5C44E 1TWCF 3S1MF 4ZH4E 3GTPE 3RZDF 2Y0SH 4GZYE 2JA7E 3K7AF 3HOUE 4LJZE 2VUMF 4G7ZE 3H3VF 4G7HE 3HOVE 4A3BE 4OIPE 4OIQE 3CQZE
chains in the Genus database with same CATH topology
3HOWE 5M3FE 2JA6E 3I4ME 3GTGE 1EIKA 1SFOE 1TWFE 3S1RE 4X6AE 4BY1E 4A3DE 2NVYE 2R92E 4Y52E 4A3GE 3GTLE 4QIWH 2E2IE 3HOXE 2YU9E 4A3EE 2E2HE 3RZOE 5C4XE 5FLME 2PMZH 3PO2E 1I6HE 4C3IE 4A3ME 5IYBE 2WAQH 4A3IE 2JA5E 3S2DE 3S17E 3S1QE 4A3LE 3HOZE 3S2HE 4AYBH 1WCME 5C4JE 2E2JE 5IYCE 5M3ME 3H0GE 3HKZH 3S16E 4BBSE 2NVTE 2NVXE 1I50E 3GTOE 1Y1WE 3S14E 4A93E 1TWGE 3S1NE 3M4OE 3HOYE 1DZFA 4Y7NE 2B63E 4A3CE 3S1ME 5IYDE 5M5YE 3GTJE 3RZDE 3GTME 5IP7E 1TWAE 5M5WE 4C3JE 4A3KE 3GTKE 3FKIE 5M5XE 4BY7E 1I3QE 1R9TE 3S15E 4C3HE 4BXXE 1K83E 4A3JE 3M3YE 5FJ8E 5IP9E 2WB1H 3I4NE 4A3FE 2NVQE 2R7ZE 4BBRE 3GTQE 1TWCE 2R93E 1Y1VE 3K7AE 5C3EE 2VUME 4C2ME 3PO3E 1TWHE 2JA8E 5C44E 3GTPE 2Y0SH 2JA7E 3HOUE 3H3VF 3HOVE 4A3BE 3CQZE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HOW E;  5M3F E;  2JA6 E;  3I4M E;  3GTG E;  1EIK A;  1SFO E;  1TWF E;  3S1R E;  4X6A E;  4BY1 E;  4A3D E;  2NVY E;  2R92 E;  4Y52 E;  4A3G E;  3GTL E;  4QIW H;  2E2I E;  3HOX E;  2YU9 E;  4A3E E;  2E2H E;  3RZO E;  5C4X E;  5FLM E;  2PMZ H;  3PO2 E;  1I6H E;  4C3I E;  4A3M E;  5IYB E;  2WAQ H;  4A3I E;  2JA5 E;  3S2D E;  3S17 E;  3S1Q E;  4A3L E;  3HOZ E;  3S2H E;  4AYB H;  1WCM E;  5C4J E;  2E2J E;  5IYC E;  5M3M E;  3H0G E;  3HKZ H;  3S16 E;  4BBS E;  2NVT E;  2NVX E;  1I50 E;  3GTO E;  1Y1W E;  3S14 E;  4A93 E;  1TWG E;  3S1N E;  3M4O E;  3HOY E;  1DZF A;  4Y7N E;  2B63 E;  4A3C E;  3S1M E;  5IYD E;  5M5Y E;  3GTJ E;  3RZD E;  3GTM E;  5IP7 E;  1TWA E;  5M5W E;  4C3J E;  4A3K E;  3GTK E;  3FKI E;  5M5X E;  4BY7 E;  1I3Q E;  1R9T E;  3S15 E;  4C3H E;  4BXX E;  1K83 E;  4A3J E;  3M3Y E;  5FJ8 E;  5IP9 E;  2WB1 H;  3I4N E;  4A3F E;  2NVQ E;  2R7Z E;  4BBR E;  3GTQ E;  1TWC E;  2R93 E;  1Y1V E;  3K7A E;  5C3E E;  2VUM E;  4C2M E;  3PO3 E;  1TWH E;  2JA8 E;  5C44 E;  3GTP E;  2Y0S H;  2JA7 E;  3HOU E;  3H3V F;  3HOV E;  4A3B E;  3CQZ E; 
#chains in the Genus database with same CATH topology
 3HOW E;  5M3F E;  1ZYR E;  2JA6 E;  3I4M E;  3GTG E;  3WOD E;  5M5W F;  1SFO E;  1TWF E;  5D4D E;  2JA8 F;  1EIK A;  5C44 F;  3S1R E;  4X6A E;  4BY1 E;  4A3D E;  4BY7 F;  2NVY E;  2R92 E;  2JA7 F;  4Y52 E;  4QIW K;  4A3G E;  1I6V E;  1HQM E;  1R9T F;  3HOU F;  3HOV F;  1K83 F;  3GTL E;  4QIW H;  4A3B F;  5TMC E;  3HOW F;  5M3F F;  4Q4Z E;  2JA6 F;  3I4M F;  1TWF F;  2E2I E;  3HOX E;  2PMZ K;  2YU9 E;  4A3E E;  2E2H E;  3S1R F;  3RZO E;  4LK0 E;  5C4X E;  5FLM E;  4BY1 F;  2PMZ H;  2NVY F;  4MEX E;  4G7O E;  3PO2 E;  2R92 F;  3DXJ E;  2BE5 E;  2R93 F;  1Y1V F;  1I6H E;  4C3I E;  2WAQ K;  4Q5S E;  4A3M E;  5C3E F;  3M3Y F;  4JK1 E;  5IYB E;  4C2M F;  2WAQ H;  4A3I E;  2JA5 E;  3S2D E;  2E2I F;  4AYB K;  4YFN E;  3S17 E;  3S1Q E;  4A3L E;  1YNN K;  4OIN E;  3HOZ E;  3S2H E;  2YU9 F;  4AYB H;  2E2H F;  1WCM E;  5C4J E;  5FLM F;  5C4X F;  2E2J E;  3PO2 F;  2O5I E;  4LK1 E;  3HKZ K;  5IYC E;  3GTP F;  5D4C E;  1I6H F;  5M3M E;  4C3I F;  3H0G E;  3HKZ H;  4KMU E;  4KN7 E;  5IYB F;  3S16 E;  4BBS E;  4A3I F;  3CQZ F;  2JA5 F;  4A3D F;  3S2D F;  2NVT E;  5D4E E;  2NVX E;  3GTG F;  4A3L F;  1I50 E;  3GTO E;  2A6H E;  2KRX A;  1SFO F;  3S2H F;  1Y1W E;  1WCM F;  5C4J F;  3S14 E;  4A93 E;  2E2J F;  2O5J E;  5E17 E;  5IPL E;  1TWG E;  4Y52 F;  3S1N E;  3H0G F;  5M3M F;  3M4O E;  3HOY E;  4A3G F;  3S16 F;  4YFX E;  3GTL F;  4BBS F;  1DZF A;  4Y7N E;  2NVT F;  1YNJ K;  2A69 E;  2B63 E;  1I50 F;  3GTO F;  4A3C E;  3S1M E;  1QKL A;  3HOX F;  5IYD E;  1Y1W F;  5M5Y E;  3S14 F;  4A93 F;  3GTJ E;  4YFK E;  4A3E F;  3RZD E;  3RZO F;  4OIO E;  3GTM E;  3EQL E;  4X6A F;  4MEY E;  5IP7 E;  3M4O F;  4YG2 E;  4XSZ E;  3HOY F;  2CW0 E;  3H3V G;  1IW7 E;  4A3M F;  1TWA E;  5M5W E;  4C3J E;  4A3K E;  4Y7N F;  4XSX E;  3GTK E;  2B63 F;  2WB1 I;  3FKI E;  4A3C F;  2A6E E;  5M5X E;  5IYD F;  4OIR E;  5M5Y F;  3S17 F;  3HOZ F;  3GTJ F;  4BY7 E;  3S1Q F;  1I3Q E;  5TMF E;  4XLN E;  3GTM F;  1R9T E;  3S15 E;  5E18 E;  4C3H E;  5IYC F;  4BXX E;  1K83 E;  1SMY E;  4A3J E;  3M3Y E;  5IP7 F;  5FJ8 E;  5IP9 E;  2A68 E;  1TWH F;  4KN4 E;  1TWA F;  2WB1 H;  3I4N E;  4A3F E;  4C3J F;  4A3K F;  2PPB E;  3PO3 F;  2NVQ E;  3GTK F;  4LLG E;  3FKI F;  2R7Z E;  4BBR E;  5M5X F;  2NVX F;  3GTQ E;  4MQ9 E;  4XLP E;  1TWC E;  1I3Q F;  2R93 E;  1Y1V E;  3S15 F;  4C3H F;  3K7A E;  4BXX F;  5C3E E;  2VUM E;  1TWG F;  4A3J F;  2Y0S I;  5IP9 F;  5FJ8 F;  4C2M E;  3PO3 E;  1TWH E;  3S1N F;  5BYH E;  3I4N F;  4A3F F;  2NVQ F;  2JA8 E;  2R7Z F;  4BBR F;  3GTQ F;  5C44 E;  1TWC F;  3S1M F;  4ZH4 E;  3GTP E;  3RZD F;  2Y0S H;  4GZY E;  2JA7 E;  3K7A F;  3HOU E;  4LJZ E;  2VUM F;  4G7Z E;  3H3V F;  4G7H E;  3HOV E;  4A3B E;  4OIP E;  4OIQ E;  3CQZ E; 
#chains in the Genus database with same CATH homology
 3HOW E;  5M3F E;  2JA6 E;  3I4M E;  3GTG E;  1EIK A;  1SFO E;  1TWF E;  3S1R E;  4X6A E;  4BY1 E;  4A3D E;  2NVY E;  2R92 E;  4Y52 E;  4A3G E;  3GTL E;  4QIW H;  2E2I E;  3HOX E;  2YU9 E;  4A3E E;  2E2H E;  3RZO E;  5C4X E;  5FLM E;  2PMZ H;  3PO2 E;  1I6H E;  4C3I E;  4A3M E;  5IYB E;  2WAQ H;  4A3I E;  2JA5 E;  3S2D E;  3S17 E;  3S1Q E;  4A3L E;  3HOZ E;  3S2H E;  4AYB H;  1WCM E;  5C4J E;  2E2J E;  5IYC E;  5M3M E;  3H0G E;  3HKZ H;  3S16 E;  4BBS E;  2NVT E;  2NVX E;  1I50 E;  3GTO E;  1Y1W E;  3S14 E;  4A93 E;  1TWG E;  3S1N E;  3M4O E;  3HOY E;  1DZF A;  4Y7N E;  2B63 E;  4A3C E;  3S1M E;  5IYD E;  5M5Y E;  3GTJ E;  3RZD E;  3GTM E;  5IP7 E;  1TWA E;  5M5W E;  4C3J E;  4A3K E;  3GTK E;  3FKI E;  5M5X E;  4BY7 E;  1I3Q E;  1R9T E;  3S15 E;  4C3H E;  4BXX E;  1K83 E;  4A3J E;  3M3Y E;  5FJ8 E;  5IP9 E;  2WB1 H;  3I4N E;  4A3F E;  2NVQ E;  2R7Z E;  4BBR E;  3GTQ E;  1TWC E;  2R93 E;  1Y1V E;  3K7A E;  5C3E E;  2VUM E;  4C2M E;  3PO3 E;  1TWH E;  2JA8 E;  5C44 E;  3GTP E;  2Y0S H;  2JA7 E;  3HOU E;  3H3V F;  3HOV E;  4A3B E;  3CQZ E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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