3I4ME

8-oxoguanine containing rna polymerase ii elongation complex d
Total Genus 50
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Transcription,transferase/dna-rna hybrid
publication title Molecular basis of transcriptional mutagenesis at 8-oxoguanine
pubmed doi rcsb
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 50
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2009-07-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3i4mE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3i4mE02
3PO3E 4BXXE 5FJ8E 2NVTE 5M3FE 5FLME 2WB1H 3S2DE 5M3ME 4BY1E 3S14E 2R7ZE 1WCME 4BBSE 3S2HE 1I50E 1TWCE 3S16E 2NVXE 3GTQE 3I4NE 3M3YE 4C2ME 2JA6E 3GTPE 4A3FE 4QIWH 5M5XE 1DZFA 4BY7E 4AYBH 1I3QE 3I4ME 5C4XE 3S1ME 3FKIE 4Y52E 2NVYE 3M4OE 2B63E 2PMZH 3HKZH 4A3GE 4X6AE 1TWAE 5IYCE 5IP7E 5C3EE 4C3IE 5M5YE 3S1QE 2JA7E 3CQZE 2JA8E 5C4JE 3HOUE 2VUME 5M5WE 5C44E 1TWHE 2E2JE 1I6HE 3S15E 3HOZE 4A3KE 2NVQE 1TWGE 2JA5E 4C3JE 1SFOE 3S1RE 1R9TE 1K83E 3PO2E 3GTOE 4A3BE 3GTGE 3HOYE 3H0GE 5IYDE 2R92E 2E2HE 4C3HE 3GTJE 4A3EE 3RZOE 4A3ME 1Y1VE 4A3IE 4A3JE 3GTME 2R93E 3HOWE 4A93E 5IP9E 3HOVE 3S17E 3H3VF 2WAQH 2E2IE 4BBRE 4A3DE 1EIKA 4A3CE 2Y0SH 3HOXE 4A3LE 2YU9E 3S1NE 3K7AE 3RZDE 3GTKE 1Y1WE 5IYBE 4Y7NE 1TWFE 3GTLE
chains in the Genus database with same CATH superfamily
3PO3E 3GTOF 4A3BF 3GTKF 1Y1WF 5IYBF 4OIPE 4BXXE 4Y7NF 4GZYE 1TWFF 4OIQE 2WAQK 3DXJE 5FJ8E 2NVTE 2R92F 4C3HF 4BXXF 5M3FE 4A3EF 3RZOF 4MEXE 5FLME 4LK0E 4A3MF 2WB1H 4XSZE 4A3JF 3S2DE 3GTMF 5M3ME 4BY1E 5M3FF 2R93F 3S14E 2R7ZE 3HOWF 1WCME 4QIWK 4A93F 3HOVF 4BY1F 4BBSE 3S2HE 1I50E 5E18E 2R7ZF 1TWCE 3S16E 1QKLA 1WCMF 2NVXE 3GTQE 4G7OE 4JK1E 3I4NE 3M3YE 4OINE 2O5JE 4C2ME 2JA6E 3GTPE 4BBRF 4A3DF 4A3FE 4QIWH 5M5XE 4A3LF 2YU9F 3S1NF 4MEYE 3K7AF 2JA6F 1DZFA 3RZDF 4BY7E 4XSXE 4AYBH 4KN7E 4YG2E 1I3QE 3GTLF 3PO3F 3I4ME 5C4XE 3S1ME 2PPBE 4LLGE 3FKIE 5FJ8F 2NVTF 4Y52E 2NVYE 3M4OE 2B63E 2PMZH 3HKZH 5D4CE 5FLMF 4A3GE 4X6AE 3S2DF 1TWAE 5IYCE 5IP7E 5M3MF 4AYBK 3S14F 5C3EE 5IPLE 4C3IE 5M5YE 4A3GF 3S1QE 2JA7E 3CQZE 2JA8E 5C4JE 3S2HF 1I50F 3HOUE 4BBSF 1TWCF 3S16F 1IW7E 4C3IF 2NVXF 3GTQF 2VUME 3I4NF 1YNNK 3M3YF 2A68E 4C2MF 3HOUF 3GTPF 2PMZK 4A3FF 4XLPE 3HKZK 5M5WE 2KRXA 5M5XF 5C44E 1TWHE 4BY7F 4ZH4E 2E2JE 4Q5SE 5M5WF 5C44F 1HQME 1I6HE 3S15E 1TWHF 4MQ9E 1I3QF 4OIRE 2E2JF 3HOZE 4XLNE 3I4MF 4Q4ZE 4A3KE 5C4XF 2NVQE 1ZYRE 1TWGE 3S1MF 2JA5E 3S15F 5TMFE 4C3JE 3FKIF 1SFOE 3S1RE 1R9TE 1K83E 2A69E 2NVYF 4Y52F 4A3KF 2A6EE 4KMUE 3M4OF 2B63F 3PO2E 1TWGF 1YNJK 3GTOE 4A3BE 4C3JF 4YFKE 1SMYE 1SFOF 2JA8F 4X6AF 3GTGE 1TWAF 5TMCE 5IP7F 5IYCF 4YFXE 5E17E 3HOYE 3H0GE 2A6HE 5IYDE 2R92E 5C3EF 2E2HE 4C3HE 5M5YF 3S1QF 3GTGF 3GTJE 4A3EE 4LK1E 3RZOE 2WB1I 3CQZF 5C4JF 4A3ME 2JA7F 1Y1VE 4A3IE 4A3JE 3H0GF 5BYHE 5IYDF 3GTME 5D4DE 2E2HF 2BE5E 2VUMF 2R93E 3GTJF 3H3VG 3HOWE 4A93E 1Y1VF 5IP9E 3HOVE 4G7ZE 4A3IF 4OIOE 3S17E 3H3VF 1I6VE 3EQLE 2Y0SI 5IP9F 3S17F 4KN4E 2WAQH 2E2IE 3WODE 1I6HF 4BBRE 4A3DE 2CW0E 4A3CE 4YFNE 2Y0SH 5D4EE 3HOZF 3HOYF 1EIKA 3HOXE 4A3LE 2YU9E 3S1NE 2E2IF 3K7AE 2NVQF 3RZDE 2JA5F 4A3CF 3GTKE 1Y1WE 5IYBE 1K83F 4LJZE 3HOXF 3S1RF 4Y7NE 1R9TF 2O5IE 4G7HE 3PO2F 1TWFE 3GTLE
chains in the Genus database with same CATH topology
3PO3E 4BXXE 5FJ8E 2NVTE 5M3FE 5FLME 2WB1H 3S2DE 5M3ME 4BY1E 3S14E 2R7ZE 1WCME 4BBSE 3S2HE 1I50E 1TWCE 3S16E 2NVXE 3GTQE 3I4NE 3M3YE 4C2ME 2JA6E 3GTPE 4A3FE 4QIWH 5M5XE 1DZFA 4BY7E 4AYBH 1I3QE 3I4ME 5C4XE 3S1ME 3FKIE 4Y52E 2NVYE 3M4OE 2B63E 2PMZH 3HKZH 4A3GE 4X6AE 1TWAE 5IYCE 5IP7E 5C3EE 4C3IE 5M5YE 3S1QE 2JA7E 3CQZE 2JA8E 5C4JE 3HOUE 2VUME 5M5WE 5C44E 1TWHE 2E2JE 1I6HE 3S15E 3HOZE 4A3KE 2NVQE 1TWGE 2JA5E 4C3JE 1SFOE 3S1RE 1R9TE 1K83E 3PO2E 3GTOE 4A3BE 3GTGE 3HOYE 3H0GE 5IYDE 2R92E 2E2HE 4C3HE 3GTJE 4A3EE 3RZOE 4A3ME 1Y1VE 4A3IE 4A3JE 3GTME 2R93E 3HOWE 4A93E 5IP9E 3HOVE 3S17E 3H3VF 2WAQH 2E2IE 4BBRE 4A3DE 1EIKA 4A3CE 2Y0SH 3HOXE 4A3LE 2YU9E 3S1NE 3K7AE 3RZDE 3GTKE 1Y1WE 5IYBE 4Y7NE 1TWFE 3GTLE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PO3 E;  4BXX E;  5FJ8 E;  2NVT E;  5M3F E;  5FLM E;  2WB1 H;  3S2D E;  5M3M E;  4BY1 E;  3S14 E;  2R7Z E;  1WCM E;  4BBS E;  3S2H E;  1I50 E;  1TWC E;  3S16 E;  2NVX E;  3GTQ E;  3I4N E;  3M3Y E;  4C2M E;  2JA6 E;  3GTP E;  4A3F E;  4QIW H;  5M5X E;  1DZF A;  4BY7 E;  4AYB H;  1I3Q E;  3I4M E;  5C4X E;  3S1M E;  3FKI E;  4Y52 E;  2NVY E;  3M4O E;  2B63 E;  2PMZ H;  3HKZ H;  4A3G E;  4X6A E;  1TWA E;  5IYC E;  5IP7 E;  5C3E E;  4C3I E;  5M5Y E;  3S1Q E;  2JA7 E;  3CQZ E;  2JA8 E;  5C4J E;  3HOU E;  2VUM E;  5M5W E;  5C44 E;  1TWH E;  2E2J E;  1I6H E;  3S15 E;  3HOZ E;  4A3K E;  2NVQ E;  1TWG E;  2JA5 E;  4C3J E;  1SFO E;  3S1R E;  1R9T E;  1K83 E;  3PO2 E;  3GTO E;  4A3B E;  3GTG E;  3HOY E;  3H0G E;  5IYD E;  2R92 E;  2E2H E;  4C3H E;  3GTJ E;  4A3E E;  3RZO E;  4A3M E;  1Y1V E;  4A3I E;  4A3J E;  3GTM E;  2R93 E;  3HOW E;  4A93 E;  5IP9 E;  3HOV E;  3S17 E;  3H3V F;  2WAQ H;  2E2I E;  4BBR E;  4A3D E;  1EIK A;  4A3C E;  2Y0S H;  3HOX E;  4A3L E;  2YU9 E;  3S1N E;  3K7A E;  3RZD E;  3GTK E;  1Y1W E;  5IYB E;  4Y7N E;  1TWF E;  3GTL E; 
#chains in the Genus database with same CATH topology
 3PO3 E;  3GTO F;  4A3B F;  3GTK F;  1Y1W F;  5IYB F;  4OIP E;  4BXX E;  4Y7N F;  4GZY E;  1TWF F;  4OIQ E;  2WAQ K;  3DXJ E;  5FJ8 E;  2NVT E;  2R92 F;  4C3H F;  4BXX F;  5M3F E;  4A3E F;  3RZO F;  4MEX E;  5FLM E;  4LK0 E;  4A3M F;  2WB1 H;  4XSZ E;  4A3J F;  3S2D E;  3GTM F;  5M3M E;  4BY1 E;  5M3F F;  2R93 F;  3S14 E;  2R7Z E;  3HOW F;  1WCM E;  4QIW K;  4A93 F;  3HOV F;  4BY1 F;  4BBS E;  3S2H E;  1I50 E;  5E18 E;  2R7Z F;  1TWC E;  3S16 E;  1QKL A;  1WCM F;  2NVX E;  3GTQ E;  4G7O E;  4JK1 E;  3I4N E;  3M3Y E;  4OIN E;  2O5J E;  4C2M E;  2JA6 E;  3GTP E;  4BBR F;  4A3D F;  4A3F E;  4QIW H;  5M5X E;  4A3L F;  2YU9 F;  3S1N F;  4MEY E;  3K7A F;  2JA6 F;  1DZF A;  3RZD F;  4BY7 E;  4XSX E;  4AYB H;  4KN7 E;  4YG2 E;  1I3Q E;  3GTL F;  3PO3 F;  3I4M E;  5C4X E;  3S1M E;  2PPB E;  4LLG E;  3FKI E;  5FJ8 F;  2NVT F;  4Y52 E;  2NVY E;  3M4O E;  2B63 E;  2PMZ H;  3HKZ H;  5D4C E;  5FLM F;  4A3G E;  4X6A E;  3S2D F;  1TWA E;  5IYC E;  5IP7 E;  5M3M F;  4AYB K;  3S14 F;  5C3E E;  5IPL E;  4C3I E;  5M5Y E;  4A3G F;  3S1Q E;  2JA7 E;  3CQZ E;  2JA8 E;  5C4J E;  3S2H F;  1I50 F;  3HOU E;  4BBS F;  1TWC F;  3S16 F;  1IW7 E;  4C3I F;  2NVX F;  3GTQ F;  2VUM E;  3I4N F;  1YNN K;  3M3Y F;  2A68 E;  4C2M F;  3HOU F;  3GTP F;  2PMZ K;  4A3F F;  4XLP E;  3HKZ K;  5M5W E;  2KRX A;  5M5X F;  5C44 E;  1TWH E;  4BY7 F;  4ZH4 E;  2E2J E;  4Q5S E;  5M5W F;  5C44 F;  1HQM E;  1I6H E;  3S15 E;  1TWH F;  4MQ9 E;  1I3Q F;  4OIR E;  2E2J F;  3HOZ E;  4XLN E;  3I4M F;  4Q4Z E;  4A3K E;  5C4X F;  2NVQ E;  1ZYR E;  1TWG E;  3S1M F;  2JA5 E;  3S15 F;  5TMF E;  4C3J E;  3FKI F;  1SFO E;  3S1R E;  1R9T E;  1K83 E;  2A69 E;  2NVY F;  4Y52 F;  4A3K F;  2A6E E;  4KMU E;  3M4O F;  2B63 F;  3PO2 E;  1TWG F;  1YNJ K;  3GTO E;  4A3B E;  4C3J F;  4YFK E;  1SMY E;  1SFO F;  2JA8 F;  4X6A F;  3GTG E;  1TWA F;  5TMC E;  5IP7 F;  5IYC F;  4YFX E;  5E17 E;  3HOY E;  3H0G E;  2A6H E;  5IYD E;  2R92 E;  5C3E F;  2E2H E;  4C3H E;  5M5Y F;  3S1Q F;  3GTG F;  3GTJ E;  4A3E E;  4LK1 E;  3RZO E;  2WB1 I;  3CQZ F;  5C4J F;  4A3M E;  2JA7 F;  1Y1V E;  4A3I E;  4A3J E;  3H0G F;  5BYH E;  5IYD F;  3GTM E;  5D4D E;  2E2H F;  2BE5 E;  2VUM F;  2R93 E;  3GTJ F;  3H3V G;  3HOW E;  4A93 E;  1Y1V F;  5IP9 E;  3HOV E;  4G7Z E;  4A3I F;  4OIO E;  3S17 E;  3H3V F;  1I6V E;  3EQL E;  2Y0S I;  5IP9 F;  3S17 F;  4KN4 E;  2WAQ H;  2E2I E;  3WOD E;  1I6H F;  4BBR E;  4A3D E;  2CW0 E;  4A3C E;  4YFN E;  2Y0S H;  5D4E E;  3HOZ F;  3HOY F;  1EIK A;  3HOX E;  4A3L E;  2YU9 E;  3S1N E;  2E2I F;  3K7A E;  2NVQ F;  3RZD E;  2JA5 F;  4A3C F;  3GTK E;  1Y1W E;  5IYB E;  1K83 F;  4LJZ E;  3HOX F;  3S1R F;  4Y7N E;  1R9T F;  2O5I E;  4G7H E;  3PO2 F;  1TWF E;  3GTL E; 
#chains in the Genus database with same CATH homology
 3PO3 E;  4BXX E;  5FJ8 E;  2NVT E;  5M3F E;  5FLM E;  2WB1 H;  3S2D E;  5M3M E;  4BY1 E;  3S14 E;  2R7Z E;  1WCM E;  4BBS E;  3S2H E;  1I50 E;  1TWC E;  3S16 E;  2NVX E;  3GTQ E;  3I4N E;  3M3Y E;  4C2M E;  2JA6 E;  3GTP E;  4A3F E;  4QIW H;  5M5X E;  1DZF A;  4BY7 E;  4AYB H;  1I3Q E;  3I4M E;  5C4X E;  3S1M E;  3FKI E;  4Y52 E;  2NVY E;  3M4O E;  2B63 E;  2PMZ H;  3HKZ H;  4A3G E;  4X6A E;  1TWA E;  5IYC E;  5IP7 E;  5C3E E;  4C3I E;  5M5Y E;  3S1Q E;  2JA7 E;  3CQZ E;  2JA8 E;  5C4J E;  3HOU E;  2VUM E;  5M5W E;  5C44 E;  1TWH E;  2E2J E;  1I6H E;  3S15 E;  3HOZ E;  4A3K E;  2NVQ E;  1TWG E;  2JA5 E;  4C3J E;  1SFO E;  3S1R E;  1R9T E;  1K83 E;  3PO2 E;  3GTO E;  4A3B E;  3GTG E;  3HOY E;  3H0G E;  5IYD E;  2R92 E;  2E2H E;  4C3H E;  3GTJ E;  4A3E E;  3RZO E;  4A3M E;  1Y1V E;  4A3I E;  4A3J E;  3GTM E;  2R93 E;  3HOW E;  4A93 E;  5IP9 E;  3HOV E;  3S17 E;  3H3V F;  2WAQ H;  2E2I E;  4BBR E;  4A3D E;  1EIK A;  4A3C E;  2Y0S H;  3HOX E;  4A3L E;  2YU9 E;  3S1N E;  3K7A E;  3RZD E;  3GTK E;  1Y1W E;  5IYB E;  4Y7N E;  1TWF E;  3GTL E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...