3IW3A

Crystal structure of hyperthermophilic nitrilase
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
261
structure length
260
Chain Sequence
VKVAYVQMNPQILEPDKNYSKAEKLIKEASKQGAQLVVLPELFDTGYNFETREEVFEIAQKIPEGETTTFLMDVARDTGVYIVAGTAEKDGDVLYNSAVVVGPRGFIGKYRKIHLFYREKFFFEPGDLGFRVFDLGFMKVGVMIFDWFFPESARTLALKGADVIAHPANLVMPYAPRAMPIRALENKVYTVTADRVGEERGLKFIGKSLIASPKAEVLSMASETEEEVGVAEIDLSLVRNKRINDLNDIFKDRREEYYFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic analysis of a thermoactive nitrilase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pyrococcus abyssi
molecule keywords Nitrilase
total genus 88
structure length 260
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.5.5.1: Nitrilase.
pdb deposition date 2009-09-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 3iw3A00
2DYVA 4KZFA 1UF8A 5H8IA 3P8KA 1UF7A 3KLCA 2W1VA 2GGKA 4HGDA 2DYUA 4CYYA 5JQNA 1FO6A 3ILVA 4IZSA 2E2KA 2E2LA 4IZVA 4IZUA 3SDBA 3SEQA 1F89A 1J31A 4HG3A 3HKXA 1UF4A 3KI8A 1UF5A 4IZWA 2VHHA 4LF0A 4GYNA 3SZGA 2E11A 2VHIA 4H5UA 2PLQA 4CYFA 2UXYA 3IVZA 3IW3A 4F4HA 5KHAA 4IZTA 1ERZA 4CYGA 3DLAA 5H8LA 4GYLA 5H8JA 5H8KA 3N05A 4HG5A 3SEZA 1EMSA 3WUYA 3SYTA 2GGLA
chains in the Genus database with same CATH superfamily
2DYVA 4KZFA 1UF8A 5H8IA 3P8KA 1UF7A 3KLCA 2W1VA 2GGKA 4HGDA 2DYUA 4CYYA 5JQNA 1FO6A 3ILVA 4IZSA 2E2KA 2E2LA 4IZVA 4IZUA 3SDBA 3SEQA 1F89A 1J31A 4HG3A 3HKXA 1UF4A 3KI8A 1UF5A 4IZWA 2VHHA 4LF0A 4GYNA 3SZGA 2E11A 2VHIA 4H5UA 2PLQA 4CYFA 2UXYA 3IVZA 3IW3A 4F4HA 5KHAA 4IZTA 1ERZA 4CYGA 3DLAA 5H8LA 4GYLA 5H8JA 5H8KA 3N05A 4HG5A 3SEZA 1EMSA 3WUYA 3SYTA 2GGLA
chains in the Genus database with same CATH topology
2DYVA 4KZFA 1UF8A 5H8IA 3P8KA 1UF7A 3KLCA 2W1VA 2GGKA 4HGDA 2DYUA 4CYYA 5JQNA 1FO6A 3ILVA 4IZSA 2E2KA 2E2LA 4IZVA 4IZUA 3SDBA 3SEQA 1F89A 1J31A 4HG3A 3HKXA 1UF4A 3KI8A 1UF5A 4IZWA 2VHHA 4LF0A 4GYNA 3SZGA 2E11A 2VHIA 4H5UA 2PLQA 4CYFA 2UXYA 3IVZA 3IW3A 4F4HA 5KHAA 4IZTA 1ERZA 4CYGA 3DLAA 5H8LA 4GYLA 5H8JA 5H8KA 3N05A 4HG5A 3SEZA 1EMSA 3WUYA 3SYTA 2GGLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DYV A;  4KZF A;  1UF8 A;  5H8I A;  3P8K A;  1UF7 A;  3KLC A;  2W1V A;  2GGK A;  4HGD A;  2DYU A;  4CYY A;  5JQN A;  1FO6 A;  3ILV A;  4IZS A;  2E2K A;  2E2L A;  4IZV A;  4IZU A;  3SDB A;  3SEQ A;  1F89 A;  1J31 A;  4HG3 A;  3HKX A;  1UF4 A;  3KI8 A;  1UF5 A;  4IZW A;  2VHH A;  4LF0 A;  4GYN A;  3SZG A;  2E11 A;  2VHI A;  4H5U A;  2PLQ A;  4CYF A;  2UXY A;  3IVZ A;  3IW3 A;  4F4H A;  5KHA A;  4IZT A;  1ERZ A;  4CYG A;  3DLA A;  5H8L A;  4GYL A;  5H8J A;  5H8K A;  3N05 A;  4HG5 A;  3SEZ A;  1EMS A;  3WUY A;  3SYT A;  2GGL A; 
#chains in the Genus database with same CATH topology
 2DYV A;  4KZF A;  1UF8 A;  5H8I A;  3P8K A;  1UF7 A;  3KLC A;  2W1V A;  2GGK A;  4HGD A;  2DYU A;  4CYY A;  5JQN A;  1FO6 A;  3ILV A;  4IZS A;  2E2K A;  2E2L A;  4IZV A;  4IZU A;  3SDB A;  3SEQ A;  1F89 A;  1J31 A;  4HG3 A;  3HKX A;  1UF4 A;  3KI8 A;  1UF5 A;  4IZW A;  2VHH A;  4LF0 A;  4GYN A;  3SZG A;  2E11 A;  2VHI A;  4H5U A;  2PLQ A;  4CYF A;  2UXY A;  3IVZ A;  3IW3 A;  4F4H A;  5KHA A;  4IZT A;  1ERZ A;  4CYG A;  3DLA A;  5H8L A;  4GYL A;  5H8J A;  5H8K A;  3N05 A;  4HG5 A;  3SEZ A;  1EMS A;  3WUY A;  3SYT A;  2GGL A; 
#chains in the Genus database with same CATH homology
 2DYV A;  4KZF A;  1UF8 A;  5H8I A;  3P8K A;  1UF7 A;  3KLC A;  2W1V A;  2GGK A;  4HGD A;  2DYU A;  4CYY A;  5JQN A;  1FO6 A;  3ILV A;  4IZS A;  2E2K A;  2E2L A;  4IZV A;  4IZU A;  3SDB A;  3SEQ A;  1F89 A;  1J31 A;  4HG3 A;  3HKX A;  1UF4 A;  3KI8 A;  1UF5 A;  4IZW A;  2VHH A;  4LF0 A;  4GYN A;  3SZG A;  2E11 A;  2VHI A;  4H5U A;  2PLQ A;  4CYF A;  2UXY A;  3IVZ A;  3IW3 A;  4F4H A;  5KHA A;  4IZT A;  1ERZ A;  4CYG A;  3DLA A;  5H8L A;  4GYL A;  5H8J A;  5H8K A;  3N05 A;  4HG5 A;  3SEZ A;  1EMS A;  3WUY A;  3SYT A;  2GGL A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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