3KLCA

Crystal structure of hyperthermophilic nitrilase
Total Genus 92
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
92
sequence length
261
structure length
260
Chain Sequence
VKVAYVQMNPQILEPDKNYSKAEKLIKEASKQGAQLVVLPELFDTGYNFETREEVFEIAQKIPEGETTTFLMDVARDTGVYIVAGTAEKDGDVLYNSAVVVGPRGFIGKYRKIHLFYREKFFFEPGDLGFRVFDLGFMKVGVMIFDWFFPESARTLALKGADVIAHPANLVMPYAPRAMPIRALENKVYTVTADRVGEERGLKFIGKSLIASPKAEVLSMASETEEEVGVAEIDLSLVRNKRINDLNDIFKDRREEYYFR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystallographic analysis of a thermoactive nitrilase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Pyrococcus abyssi
molecule keywords Beta ureidopropionase (Beta-alanine synthase)
total genus 92
structure length 260
sequence length 261
chains with identical sequence B
ec nomenclature ec 3.5.5.1: Nitrilase.
pdb deposition date 2009-11-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00795 CN_hydrolase Carbon-nitrogen hydrolase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.110.10 Alpha Beta 4-Layer Sandwich Nitrilase/N-carbamoyl-D-aminoacid amidohydrolase Carbon-nitrogen hydrolase 3klcA00
4LF0A 4IZUA 4IZSA 5JQNA 3KI8A 2GGKA 2E11A 5H8IA 1UF4A 3SYTA 2VHHA 4CYYA 4IZVA 2W1VA 3ILVA 1ERZA 4F4HA 4GYNA 4CYGA 3IVZA 3SEQA 3P8KA 3SEZA 1EMSA 2VHIA 4KZFA 3IW3A 2UXYA 4GYLA 1UF8A 4HGDA 5H8LA 4HG5A 3DLAA 4HG3A 3SZGA 5KHAA 3HKXA 4IZWA 2E2KA 2E2LA 1UF5A 2GGLA 3SDBA 1J31A 1UF7A 2DYUA 3N05A 4IZTA 4H5UA 1F89A 2PLQA 3KLCA 3WUYA 5H8JA 1FO6A 4CYFA 2DYVA 5H8KA
chains in the Genus database with same CATH superfamily
4LF0A 4IZUA 4IZSA 5JQNA 3KI8A 2GGKA 2E11A 5H8IA 1UF4A 3SYTA 2VHHA 4CYYA 4IZVA 2W1VA 3ILVA 1ERZA 4F4HA 4GYNA 4CYGA 3IVZA 3SEQA 3P8KA 3SEZA 1EMSA 2VHIA 4KZFA 3IW3A 2UXYA 4GYLA 1UF8A 4HGDA 5H8LA 4HG5A 3DLAA 4HG3A 3SZGA 5KHAA 3HKXA 4IZWA 2E2KA 2E2LA 1UF5A 2GGLA 3SDBA 1J31A 1UF7A 2DYUA 3N05A 4IZTA 4H5UA 1F89A 2PLQA 3KLCA 3WUYA 5H8JA 1FO6A 4CYFA 2DYVA 5H8KA
chains in the Genus database with same CATH topology
4LF0A 4IZUA 4IZSA 5JQNA 3KI8A 2GGKA 2E11A 5H8IA 1UF4A 3SYTA 2VHHA 4CYYA 4IZVA 2W1VA 3ILVA 1ERZA 4F4HA 4GYNA 4CYGA 3IVZA 3SEQA 3P8KA 3SEZA 1EMSA 2VHIA 4KZFA 3IW3A 2UXYA 4GYLA 1UF8A 4HGDA 5H8LA 4HG5A 3DLAA 4HG3A 3SZGA 5KHAA 3HKXA 4IZWA 2E2KA 2E2LA 1UF5A 2GGLA 3SDBA 1J31A 1UF7A 2DYUA 3N05A 4IZTA 4H5UA 1F89A 2PLQA 3KLCA 3WUYA 5H8JA 1FO6A 4CYFA 2DYVA 5H8KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LF0 A;  4IZU A;  4IZS A;  5JQN A;  3KI8 A;  2GGK A;  2E11 A;  5H8I A;  1UF4 A;  3SYT A;  2VHH A;  4CYY A;  4IZV A;  2W1V A;  3ILV A;  1ERZ A;  4F4H A;  4GYN A;  4CYG A;  3IVZ A;  3SEQ A;  3P8K A;  3SEZ A;  1EMS A;  2VHI A;  4KZF A;  3IW3 A;  2UXY A;  4GYL A;  1UF8 A;  4HGD A;  5H8L A;  4HG5 A;  3DLA A;  4HG3 A;  3SZG A;  5KHA A;  3HKX A;  4IZW A;  2E2K A;  2E2L A;  1UF5 A;  2GGL A;  3SDB A;  1J31 A;  1UF7 A;  2DYU A;  3N05 A;  4IZT A;  4H5U A;  1F89 A;  2PLQ A;  3KLC A;  3WUY A;  5H8J A;  1FO6 A;  4CYF A;  2DYV A;  5H8K A; 
#chains in the Genus database with same CATH topology
 4LF0 A;  4IZU A;  4IZS A;  5JQN A;  3KI8 A;  2GGK A;  2E11 A;  5H8I A;  1UF4 A;  3SYT A;  2VHH A;  4CYY A;  4IZV A;  2W1V A;  3ILV A;  1ERZ A;  4F4H A;  4GYN A;  4CYG A;  3IVZ A;  3SEQ A;  3P8K A;  3SEZ A;  1EMS A;  2VHI A;  4KZF A;  3IW3 A;  2UXY A;  4GYL A;  1UF8 A;  4HGD A;  5H8L A;  4HG5 A;  3DLA A;  4HG3 A;  3SZG A;  5KHA A;  3HKX A;  4IZW A;  2E2K A;  2E2L A;  1UF5 A;  2GGL A;  3SDB A;  1J31 A;  1UF7 A;  2DYU A;  3N05 A;  4IZT A;  4H5U A;  1F89 A;  2PLQ A;  3KLC A;  3WUY A;  5H8J A;  1FO6 A;  4CYF A;  2DYV A;  5H8K A; 
#chains in the Genus database with same CATH homology
 4LF0 A;  4IZU A;  4IZS A;  5JQN A;  3KI8 A;  2GGK A;  2E11 A;  5H8I A;  1UF4 A;  3SYT A;  2VHH A;  4CYY A;  4IZV A;  2W1V A;  3ILV A;  1ERZ A;  4F4H A;  4GYN A;  4CYG A;  3IVZ A;  3SEQ A;  3P8K A;  3SEZ A;  1EMS A;  2VHI A;  4KZF A;  3IW3 A;  2UXY A;  4GYL A;  1UF8 A;  4HGD A;  5H8L A;  4HG5 A;  3DLA A;  4HG3 A;  3SZG A;  5KHA A;  3HKX A;  4IZW A;  2E2K A;  2E2L A;  1UF5 A;  2GGL A;  3SDB A;  1J31 A;  1UF7 A;  2DYU A;  3N05 A;  4IZT A;  4H5U A;  1F89 A;  2PLQ A;  3KLC A;  3WUY A;  5H8J A;  1FO6 A;  4CYF A;  2DYV A;  5H8K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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