3M4OE

Rna polymerase ii elongation complex b
Total Genus 42
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
42
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct.
pubmed doi rcsb
molecule tags Transferase/dna-rna hybrid
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 42
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2010-03-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3m4oE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3m4oE02
3S17E 1R9TE 3S1NE 4A3LE 4A93E 2E2JE 3S14E 4Y7NE 2E2HE 2JA5E 3GTJE 2NVYE 3M3YE 2NVQE 1TWAE 2JA8E 3GTGE 5M5WE 4A3FE 4A3EE 3HOVE 4AYBH 1TWHE 4A3JE 5M5XE 3I4NE 5IYDE 4C2ME 3S1RE 3GTME 4QIWH 5IP9E 3GTLE 5M3FE 1TWGE 4Y52E 1SFOE 3I4ME 5FJ8E 1I6HE 2NVXE 4BXXE 2B63E 4A3BE 3FKIE 3PO3E 3S15E 1Y1VE 2VUME 4A3DE 1I3QE 1K83E 1WCME 2E2IE 4A3GE 4X6AE 5FLME 3S2DE 5C4XE 1EIKA 4A3IE 3HOXE 5C3EE 3CQZE 1TWFE 3K7AE 3HKZH 4C3HE 3HOUE 5M5YE 2PMZH 4C3IE 4BBRE 4A3ME 1DZFA 3RZDE 3HOZE 2WB1H 4BY7E 4BY1E 3H0GE 2JA6E 2NVTE 3H3VF 3HOYE 3HOWE 4BBSE 4A3KE 3GTQE 3RZOE 4A3CE 3GTOE 5IYCE 5M3ME 3PO2E 2Y0SH 3GTPE 1I50E 3S16E 1Y1WE 5C44E 3S1ME 2WAQH 5IYBE 3GTKE 2R92E 1TWCE 2JA7E 3S1QE 5C4JE 3S2HE 5IP7E 2R93E 2YU9E 4C3JE 3M4OE 2R7ZE
chains in the Genus database with same CATH superfamily
3S17E 1R9TE 3S1NE 2B63F 4A3LE 4A3BF 4A93E 3FKIF 4BXXF 3PO3F 3S15F 4BBRF 1Y1VF 2BE5E 2E2JE 3S14E 4KMUE 4Y7NE 2E2HE 2JA5E 4YG2E 3GTJE 2VUMF 2NVYE 4A3DF 3M3YE 1I3QF 2NVQE 1TWAE 2JA8E 1HQME 1K83F 1WCMF 3GTGE 4LJZE 1SMYE 2WB1I 2E2IF 5M5WE 4A3GF 4X6AF 4A3FE 2KRXA 4A3EE 3HOVE 5FLMF 4OIQE 3S2DF 5C4XF 4AYBH 1TWHE 4A3JE 5M5XE 3I4NE 5IYDE 4C2ME 4A3IF 3S1RE 3GTME 4QIWH 3HOXF 5IP9E 3EQLE 3GTLE 5C3EF 2WAQK 5M3FE 1TWGE 3CQZF 4Y52E 1TWFF 1SFOE 5TMFE 3I4ME 1YNNK 2A6EE 5FJ8E 3K7AF 4XLNE 4C3HF 1I6HE 3HOUF 2NVXE 4XSXE 5M5YF 4BXXE 2B63E 4A3BE 4C3IF 3FKIE 4A3MF 4G7OE 1I50F 5E17E 3PO3E 3RZDF 3HOZF 3S15E 4BY7F 4BY1F 1Y1VE 3H0GF 1I6VE 2JA6F 2NVTF 2VUME 4A3DE 2Y0SI 4YFKE 4Q5SE 1I3QE 2R92F 1K83E 1WCME 3S1QF 3HOYF 3HOWF 2E2IE 4BBSF 4A3GE 4X6AE 3DXJE 5FLME 3S2DE 5C4XE 4A3KF 3GTQF 4KN7E 3RZOF 2A69E 4A3CF 1EIKA 1R9TF 3GTOF 5IYCF 4A3IE 5M3MF 3PO2F 4A3LF 3HOXE 4OIOE 4OIRE 2CW0E 4AYBK 5C3EE 3CQZE 5D4DE 1YNJK 4LK1E 1TWFE 4MEYE 2NVYF 4QIWK 3K7AE 3HKZH 4C3HE 2A68E 4KN4E 3HOUE 3GTPF 5M5YE 2PMZH 3S16F 4C3IE 1Y1WF 4BBRE 4A3ME 5C44F 1DZFA 2PPBE 3RZDE 3HOZE 2WB1H 4BY7E 3S1MF 5D4CE 4BY1E 5IYBF 4Q4ZE 3H0GE 3GTKF 3H3VG 2JA6E 2NVTE 4C2MF 1TWCF 2JA7F 5C4JF 4OINE 5IP7F 3S2HF 2R93F 2YU9F 3H3VF 4LLGE 3HOYE 4XSZE 4C3JF 3M4OF 3HOWE 5E18E 4G7HE 4BBSE 2O5IE 2A6HE 3I4MF 2R7ZF 1ZYRE 4JK1E 4A3KE 1I6HF 3S17F 3GTQE 3RZOE 4A3CE 3S1NF 4A93F 3GTOE 1IW7E 5IYCE 5M3ME 3PO2E 5IPLE 5D4EE 5BYHE 2E2JF 3S14F 4Y7NF 4LK0E 2E2HF 2JA5F 3GTJF 4OIPE 3M3YF 2NVQF 1TWAF 4YFXE 2JA8F 3GTGF 2Y0SH 3GTPE 4MEXE 2O5JE 5M5WF 1I50E 3S16E 4G7ZE 4A3FF 1Y1WE 5C44E 3S1ME 4XLPE 4A3EF 3HOVF 4MQ9E 1TWHF 4A3JF 2WAQH 1QKLA 3HKZK 5M5XF 3I4NF 5IYDF 5IYBE 3S1RF 3GTKE 3GTMF 2PMZK 4YFNE 2R92E 1TWCE 2JA7E 3S1QE 5IP9F 5C4JE 3S2HE 5IP7E 3WODE 2R93E 3GTLF 2YU9E 5M3FF 1TWGF 4Y52F 4C3JE 3M4OE 1SFOF 5FJ8F 4GZYE 2R7ZE 5TMCE 4ZH4E 2NVXF
chains in the Genus database with same CATH topology
3S17E 1R9TE 3S1NE 4A3LE 4A93E 2E2JE 3S14E 4Y7NE 2E2HE 2JA5E 3GTJE 2NVYE 3M3YE 2NVQE 1TWAE 2JA8E 3GTGE 5M5WE 4A3FE 4A3EE 3HOVE 4AYBH 1TWHE 4A3JE 5M5XE 3I4NE 5IYDE 4C2ME 3S1RE 3GTME 4QIWH 5IP9E 3GTLE 5M3FE 1TWGE 4Y52E 1SFOE 3I4ME 5FJ8E 1I6HE 2NVXE 4BXXE 2B63E 4A3BE 3FKIE 3PO3E 3S15E 1Y1VE 2VUME 4A3DE 1I3QE 1K83E 1WCME 2E2IE 4A3GE 4X6AE 5FLME 3S2DE 5C4XE 1EIKA 4A3IE 3HOXE 5C3EE 3CQZE 1TWFE 3K7AE 3HKZH 4C3HE 3HOUE 5M5YE 2PMZH 4C3IE 4BBRE 4A3ME 1DZFA 3RZDE 3HOZE 2WB1H 4BY7E 4BY1E 3H0GE 2JA6E 2NVTE 3H3VF 3HOYE 3HOWE 4BBSE 4A3KE 3GTQE 3RZOE 4A3CE 3GTOE 5IYCE 5M3ME 3PO2E 2Y0SH 3GTPE 1I50E 3S16E 1Y1WE 5C44E 3S1ME 2WAQH 5IYBE 3GTKE 2R92E 1TWCE 2JA7E 3S1QE 5C4JE 3S2HE 5IP7E 2R93E 2YU9E 4C3JE 3M4OE 2R7ZE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S17 E;  1R9T E;  3S1N E;  4A3L E;  4A93 E;  2E2J E;  3S14 E;  4Y7N E;  2E2H E;  2JA5 E;  3GTJ E;  2NVY E;  3M3Y E;  2NVQ E;  1TWA E;  2JA8 E;  3GTG E;  5M5W E;  4A3F E;  4A3E E;  3HOV E;  4AYB H;  1TWH E;  4A3J E;  5M5X E;  3I4N E;  5IYD E;  4C2M E;  3S1R E;  3GTM E;  4QIW H;  5IP9 E;  3GTL E;  5M3F E;  1TWG E;  4Y52 E;  1SFO E;  3I4M E;  5FJ8 E;  1I6H E;  2NVX E;  4BXX E;  2B63 E;  4A3B E;  3FKI E;  3PO3 E;  3S15 E;  1Y1V E;  2VUM E;  4A3D E;  1I3Q E;  1K83 E;  1WCM E;  2E2I E;  4A3G E;  4X6A E;  5FLM E;  3S2D E;  5C4X E;  1EIK A;  4A3I E;  3HOX E;  5C3E E;  3CQZ E;  1TWF E;  3K7A E;  3HKZ H;  4C3H E;  3HOU E;  5M5Y E;  2PMZ H;  4C3I E;  4BBR E;  4A3M E;  1DZF A;  3RZD E;  3HOZ E;  2WB1 H;  4BY7 E;  4BY1 E;  3H0G E;  2JA6 E;  2NVT E;  3H3V F;  3HOY E;  3HOW E;  4BBS E;  4A3K E;  3GTQ E;  3RZO E;  4A3C E;  3GTO E;  5IYC E;  5M3M E;  3PO2 E;  2Y0S H;  3GTP E;  1I50 E;  3S16 E;  1Y1W E;  5C44 E;  3S1M E;  2WAQ H;  5IYB E;  3GTK E;  2R92 E;  1TWC E;  2JA7 E;  3S1Q E;  5C4J E;  3S2H E;  5IP7 E;  2R93 E;  2YU9 E;  4C3J E;  3M4O E;  2R7Z E; 
#chains in the Genus database with same CATH topology
 3S17 E;  1R9T E;  3S1N E;  2B63 F;  4A3L E;  4A3B F;  4A93 E;  3FKI F;  4BXX F;  3PO3 F;  3S15 F;  4BBR F;  1Y1V F;  2BE5 E;  2E2J E;  3S14 E;  4KMU E;  4Y7N E;  2E2H E;  2JA5 E;  4YG2 E;  3GTJ E;  2VUM F;  2NVY E;  4A3D F;  3M3Y E;  1I3Q F;  2NVQ E;  1TWA E;  2JA8 E;  1HQM E;  1K83 F;  1WCM F;  3GTG E;  4LJZ E;  1SMY E;  2WB1 I;  2E2I F;  5M5W E;  4A3G F;  4X6A F;  4A3F E;  2KRX A;  4A3E E;  3HOV E;  5FLM F;  4OIQ E;  3S2D F;  5C4X F;  4AYB H;  1TWH E;  4A3J E;  5M5X E;  3I4N E;  5IYD E;  4C2M E;  4A3I F;  3S1R E;  3GTM E;  4QIW H;  3HOX F;  5IP9 E;  3EQL E;  3GTL E;  5C3E F;  2WAQ K;  5M3F E;  1TWG E;  3CQZ F;  4Y52 E;  1TWF F;  1SFO E;  5TMF E;  3I4M E;  1YNN K;  2A6E E;  5FJ8 E;  3K7A F;  4XLN E;  4C3H F;  1I6H E;  3HOU F;  2NVX E;  4XSX E;  5M5Y F;  4BXX E;  2B63 E;  4A3B E;  4C3I F;  3FKI E;  4A3M F;  4G7O E;  1I50 F;  5E17 E;  3PO3 E;  3RZD F;  3HOZ F;  3S15 E;  4BY7 F;  4BY1 F;  1Y1V E;  3H0G F;  1I6V E;  2JA6 F;  2NVT F;  2VUM E;  4A3D E;  2Y0S I;  4YFK E;  4Q5S E;  1I3Q E;  2R92 F;  1K83 E;  1WCM E;  3S1Q F;  3HOY F;  3HOW F;  2E2I E;  4BBS F;  4A3G E;  4X6A E;  3DXJ E;  5FLM E;  3S2D E;  5C4X E;  4A3K F;  3GTQ F;  4KN7 E;  3RZO F;  2A69 E;  4A3C F;  1EIK A;  1R9T F;  3GTO F;  5IYC F;  4A3I E;  5M3M F;  3PO2 F;  4A3L F;  3HOX E;  4OIO E;  4OIR E;  2CW0 E;  4AYB K;  5C3E E;  3CQZ E;  5D4D E;  1YNJ K;  4LK1 E;  1TWF E;  4MEY E;  2NVY F;  4QIW K;  3K7A E;  3HKZ H;  4C3H E;  2A68 E;  4KN4 E;  3HOU E;  3GTP F;  5M5Y E;  2PMZ H;  3S16 F;  4C3I E;  1Y1W F;  4BBR E;  4A3M E;  5C44 F;  1DZF A;  2PPB E;  3RZD E;  3HOZ E;  2WB1 H;  4BY7 E;  3S1M F;  5D4C E;  4BY1 E;  5IYB F;  4Q4Z E;  3H0G E;  3GTK F;  3H3V G;  2JA6 E;  2NVT E;  4C2M F;  1TWC F;  2JA7 F;  5C4J F;  4OIN E;  5IP7 F;  3S2H F;  2R93 F;  2YU9 F;  3H3V F;  4LLG E;  3HOY E;  4XSZ E;  4C3J F;  3M4O F;  3HOW E;  5E18 E;  4G7H E;  4BBS E;  2O5I E;  2A6H E;  3I4M F;  2R7Z F;  1ZYR E;  4JK1 E;  4A3K E;  1I6H F;  3S17 F;  3GTQ E;  3RZO E;  4A3C E;  3S1N F;  4A93 F;  3GTO E;  1IW7 E;  5IYC E;  5M3M E;  3PO2 E;  5IPL E;  5D4E E;  5BYH E;  2E2J F;  3S14 F;  4Y7N F;  4LK0 E;  2E2H F;  2JA5 F;  3GTJ F;  4OIP E;  3M3Y F;  2NVQ F;  1TWA F;  4YFX E;  2JA8 F;  3GTG F;  2Y0S H;  3GTP E;  4MEX E;  2O5J E;  5M5W F;  1I50 E;  3S16 E;  4G7Z E;  4A3F F;  1Y1W E;  5C44 E;  3S1M E;  4XLP E;  4A3E F;  3HOV F;  4MQ9 E;  1TWH F;  4A3J F;  2WAQ H;  1QKL A;  3HKZ K;  5M5X F;  3I4N F;  5IYD F;  5IYB E;  3S1R F;  3GTK E;  3GTM F;  2PMZ K;  4YFN E;  2R92 E;  1TWC E;  2JA7 E;  3S1Q E;  5IP9 F;  5C4J E;  3S2H E;  5IP7 E;  3WOD E;  2R93 E;  3GTL F;  2YU9 E;  5M3F F;  1TWG F;  4Y52 F;  4C3J E;  3M4O E;  1SFO F;  5FJ8 F;  4GZY E;  2R7Z E;  5TMC E;  4ZH4 E;  2NVX F; 
#chains in the Genus database with same CATH homology
 3S17 E;  1R9T E;  3S1N E;  4A3L E;  4A93 E;  2E2J E;  3S14 E;  4Y7N E;  2E2H E;  2JA5 E;  3GTJ E;  2NVY E;  3M3Y E;  2NVQ E;  1TWA E;  2JA8 E;  3GTG E;  5M5W E;  4A3F E;  4A3E E;  3HOV E;  4AYB H;  1TWH E;  4A3J E;  5M5X E;  3I4N E;  5IYD E;  4C2M E;  3S1R E;  3GTM E;  4QIW H;  5IP9 E;  3GTL E;  5M3F E;  1TWG E;  4Y52 E;  1SFO E;  3I4M E;  5FJ8 E;  1I6H E;  2NVX E;  4BXX E;  2B63 E;  4A3B E;  3FKI E;  3PO3 E;  3S15 E;  1Y1V E;  2VUM E;  4A3D E;  1I3Q E;  1K83 E;  1WCM E;  2E2I E;  4A3G E;  4X6A E;  5FLM E;  3S2D E;  5C4X E;  1EIK A;  4A3I E;  3HOX E;  5C3E E;  3CQZ E;  1TWF E;  3K7A E;  3HKZ H;  4C3H E;  3HOU E;  5M5Y E;  2PMZ H;  4C3I E;  4BBR E;  4A3M E;  1DZF A;  3RZD E;  3HOZ E;  2WB1 H;  4BY7 E;  4BY1 E;  3H0G E;  2JA6 E;  2NVT E;  3H3V F;  3HOY E;  3HOW E;  4BBS E;  4A3K E;  3GTQ E;  3RZO E;  4A3C E;  3GTO E;  5IYC E;  5M3M E;  3PO2 E;  2Y0S H;  3GTP E;  1I50 E;  3S16 E;  1Y1W E;  5C44 E;  3S1M E;  2WAQ H;  5IYB E;  3GTK E;  2R92 E;  1TWC E;  2JA7 E;  3S1Q E;  5C4J E;  3S2H E;  5IP7 E;  2R93 E;  2YU9 E;  4C3J E;  3M4O E;  2R7Z E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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