3NIK | Genus

Total Genus 18

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	18
sequence length	82
structure length	82
Chain Sequence	GSVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases pubmed doi rcsb
molecule keywords	E3 ubiquitin-protein ligase UBR1
molecule tags	Metal binding protein
source organism	Saccharomyces cerevisiae
total genus	18
structure length	82
sequence length	82
chains with identical sequence	B, D, F
ec nomenclature	ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date	2010-06-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02207	zf-UBR	Putative zinc finger in N-recognin (UBR box)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.110.30	Mainly Beta	Ribbon	Cysteine Rich Protein	Cysteine Rich Protein	3nikA01

3NIMA 3NIJA 3NILA 3NISA 3NIHA 3NINA 3NIKA
chains in the Genus database with same CATH superfamily

5LKTA 2XUEA 1RUTX 2DARA 1X61A 4HI8B 4ASKA 5FXXA 2EHEA 2O13A 2MBVA 2CURA 2L6ZC 3NINA 5FP3A 2XQNT 2L6YB 4UF0A 4JCJA 5A1LA 3NIMA 2D8XA 1X4LA 1X64A 5FXVA 4EZHA 2CU8A 3NIKA 2CORA 3NIJA 2LXDA 3NISA 1J2OA 2DJ7A 2MIUA 1B8TA 1V6GA 2JTNA 4EZ4A 1WIGA 2CUQA 2D8YA 1CTLA 4UF0B 3ZLIA 2L4ZA 1CXXA 2LZUA 3NIHA 3F6QB 5FY1A 1IMLA 3AVRA 3IXEB 5FYMA 2EGQA 2CUPA 1M3VA 2KBXB 4KFZA 5LKUA 5LKXA 2IYBE 4BHWA 2D8ZA 1G47A 5FXZA 5FY7A 1X68A 3AVSA 3MMKA 2DLOA 1QLIA 3NILA 5FXWA 2CO8A 5LKZA 2YPAC 1X62A 3ZPOA 1A7IA 4EYUA 1WYHA 1X6AA 2DFYC 2O10A 2XJZA 1IBIA 1X3HA 4HI9B 1X63A 2XJYA 1NYPA 5FY0A 1U5SB
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3NIM A;  3NIJ A;  3NIL A;  3NIS A;  3NIH A;  3NIN A;  3NIK A; 
#chains in the Genus database with same CATH topology
 5LKT A;  2XUE A;  1RUT X;  2DAR A;  1X61 A;  4HI8 B;  4ASK A;  5FXX A;  2EHE A;  2O13 A;  2MBV A;  2CUR A;  2L6Z C;  3NIN A;  5FP3 A;  2XQN T;  2L6Y B;  4UF0 A;  4JCJ A;  5A1L A;  3NIM A;  2D8X A;  1X4L A;  1X64 A;  5FXV A;  4EZH A;  2CU8 A;  3NIK A;  2COR A;  3NIJ A;  2LXD A;  3NIS A;  1J2O A;  2DJ7 A;  2MIU A;  1B8T A;  1V6G A;  2JTN A;  4EZ4 A;  1WIG A;  2CUQ A;  2D8Y A;  1CTL A;  4UF0 B;  3ZLI A;  2L4Z A;  1CXX A;  2LZU A;  3NIH A;  3F6Q B;  5FY1 A;  1IML A;  3AVR A;  3IXE B;  5FYM A;  2EGQ A;  2CUP A;  1M3V A;  2KBX B;  4KFZ A;  5LKU A;  5LKX A;  2IYB E;  4BHW A;  2D8Z A;  1G47 A;  5FXZ A;  5FY7 A;  1X68 A;  3AVS A;  3MMK A;  2DLO A;  1QLI A;  3NIL A;  5FXW A;  2CO8 A;  5LKZ A;  2YPA C;  1X62 A;  3ZPO A;  1A7I A;  4EYU A;  1WYH A;  1X6A A;  2DFY C;  2O10 A;  2XJZ A;  1IBI A;  1X3H A;  4HI9 B;  1X63 A;  2XJY A;  1NYP A;  5FY0 A;  1U5S B; 
#chains in the Genus database with same CATH homology
 5LKT A;  2XUE A;  1RUT X;  2DAR A;  1X61 A;  4HI8 B;  4ASK A;  5FXX A;  2EHE A;  2O13 A;  2MBV A;  2CUR A;  2L6Z C;  3NIN A;  5FP3 A;  2XQN T;  2L6Y B;  4UF0 A;  4JCJ A;  5A1L A;  3NIM A;  2D8X A;  1X4L A;  1X64 A;  5FXV A;  4EZH A;  2CU8 A;  3NIK A;  2COR A;  3NIJ A;  2LXD A;  3NIS A;  1J2O A;  2DJ7 A;  2MIU A;  1B8T A;  1V6G A;  2JTN A;  4EZ4 A;  1WIG A;  2CUQ A;  2D8Y A;  1CTL A;  4UF0 B;  3ZLI A;  2L4Z A;  1CXX A;  2LZU A;  3NIH A;  3F6Q B;  5FY1 A;  1IML A;  3AVR A;  3IXE B;  5FYM A;  2EGQ A;  2CUP A;  1M3V A;  2KBX B;  4KFZ A;  5LKU A;  5LKX A;  2IYB E;  4BHW A;  2D8Z A;  1G47 A;  5FXZ A;  5FY7 A;  1X68 A;  3AVS A;  3MMK A;  2DLO A;  1QLI A;  3NIL A;  5FXW A;  2CO8 A;  5LKZ A;  2YPA C;  1X62 A;  3ZPO A;  1A7I A;  4EYU A;  1WYH A;  1X6A A;  2DFY C;  2O10 A;  2XJZ A;  1IBI A;  1X3H A;  4HI9 B;  1X63 A;  2XJY A;  1NYP A;  5FY0 A;  1U5S B;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3NIKA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations