3NIK | Genus

Total Genus 18

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	18
sequence length	82
structure length	82
Chain Sequence	GSVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases pubmed doi rcsb
molecule keywords	E3 ubiquitin-protein ligase UBR1
molecule tags	Metal binding protein
source organism	Saccharomyces cerevisiae
total genus	18
structure length	82
sequence length	82
chains with identical sequence	B, D, F
ec nomenclature	ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date	2010-06-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02207	zf-UBR	Putative zinc finger in N-recognin (UBR box)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.110.30	Mainly Beta	Ribbon	Cysteine Rich Protein	Cysteine Rich Protein	3nikA01

3NILA 3NIHA 3NIKA 3NIMA 3NISA 3NIJA 3NINA
chains in the Genus database with same CATH superfamily

2XUEA 1IBIA 1X4LA 3AVSA 1B8TA 1IMLA 2CURA 4UF0A 2D8XA 4UF0B 1QLIA 2XQNT 1V6GA 5FP3A 3NISA 2L6YB 2LZUA 5FXZA 4JCJA 1U5SB 2DJ7A 2CUQA 2JTNA 5A1LA 1J2OA 2D8ZA 5FXVA 2DFYC 3ZPOA 3NILA 2MBVA 3NIHA 1X61A 2IYBE 1X68A 5FY7A 2DLOA 3IXEB 4ASKA 1X62A 2O13A 4HI9B 1CTLA 2LXDA 3MMKA 4EZ4A 2O10A 2D8YA 3ZLIA 5LKTA 2CU8A 1WYHA 1RUTX 3AVRA 2XJYA 4EZHA 5LKXA 4BHWA 2MIUA 1G47A 1A7IA 2CORA 1CXXA 3NINA 5FY0A 2KBXB 2L6ZC 2EHEA 3NIJA 2DARA 1X63A 5FXWA 3NIMA 4KFZA 4HI8B 1NYPA 1X64A 1M3VA 2YPAC 1X6AA 5FXXA 5LKZA 5FY1A 1WIGA 2XJZA 2CO8A 3F6QB 5LKUA 5FYMA 2CUPA 2L4ZA 1X3HA 3NIKA 4EYUA 2EGQA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3NIL A;  3NIH A;  3NIK A;  3NIM A;  3NIS A;  3NIJ A;  3NIN A; 
#chains in the Genus database with same CATH topology
 2XUE A;  1IBI A;  1X4L A;  3AVS A;  1B8T A;  1IML A;  2CUR A;  4UF0 A;  2D8X A;  4UF0 B;  1QLI A;  2XQN T;  1V6G A;  5FP3 A;  3NIS A;  2L6Y B;  2LZU A;  5FXZ A;  4JCJ A;  1U5S B;  2DJ7 A;  2CUQ A;  2JTN A;  5A1L A;  1J2O A;  2D8Z A;  5FXV A;  2DFY C;  3ZPO A;  3NIL A;  2MBV A;  3NIH A;  1X61 A;  2IYB E;  1X68 A;  5FY7 A;  2DLO A;  3IXE B;  4ASK A;  1X62 A;  2O13 A;  4HI9 B;  1CTL A;  2LXD A;  3MMK A;  4EZ4 A;  2O10 A;  2D8Y A;  3ZLI A;  5LKT A;  2CU8 A;  1WYH A;  1RUT X;  3AVR A;  2XJY A;  4EZH A;  5LKX A;  4BHW A;  2MIU A;  1G47 A;  1A7I A;  2COR A;  1CXX A;  3NIN A;  5FY0 A;  2KBX B;  2L6Z C;  2EHE A;  3NIJ A;  2DAR A;  1X63 A;  5FXW A;  3NIM A;  4KFZ A;  4HI8 B;  1NYP A;  1X64 A;  1M3V A;  2YPA C;  1X6A A;  5FXX A;  5LKZ A;  5FY1 A;  1WIG A;  2XJZ A;  2CO8 A;  3F6Q B;  5LKU A;  5FYM A;  2CUP A;  2L4Z A;  1X3H A;  3NIK A;  4EYU A;  2EGQ A; 
#chains in the Genus database with same CATH homology
 2XUE A;  1IBI A;  1X4L A;  3AVS A;  1B8T A;  1IML A;  2CUR A;  4UF0 A;  2D8X A;  4UF0 B;  1QLI A;  2XQN T;  1V6G A;  5FP3 A;  3NIS A;  2L6Y B;  2LZU A;  5FXZ A;  4JCJ A;  1U5S B;  2DJ7 A;  2CUQ A;  2JTN A;  5A1L A;  1J2O A;  2D8Z A;  5FXV A;  2DFY C;  3ZPO A;  3NIL A;  2MBV A;  3NIH A;  1X61 A;  2IYB E;  1X68 A;  5FY7 A;  2DLO A;  3IXE B;  4ASK A;  1X62 A;  2O13 A;  4HI9 B;  1CTL A;  2LXD A;  3MMK A;  4EZ4 A;  2O10 A;  2D8Y A;  3ZLI A;  5LKT A;  2CU8 A;  1WYH A;  1RUT X;  3AVR A;  2XJY A;  4EZH A;  5LKX A;  4BHW A;  2MIU A;  1G47 A;  1A7I A;  2COR A;  1CXX A;  3NIN A;  5FY0 A;  2KBX B;  2L6Z C;  2EHE A;  3NIJ A;  2DAR A;  1X63 A;  5FXW A;  3NIM A;  4KFZ A;  4HI8 B;  1NYP A;  1X64 A;  1M3V A;  2YPA C;  1X6A A;  5FXX A;  5LKZ A;  5FY1 A;  1WIG A;  2XJZ A;  2CO8 A;  3F6Q B;  5LKU A;  5FYM A;  2CUP A;  2L4Z A;  1X3H A;  3NIK A;  4EYU A;  2EGQ A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3NIKA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations