3NIS | Genus

Total Genus 15

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	15
sequence length	82
structure length	82
Chain Sequence	GSVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases pubmed doi rcsb
molecule keywords	E3 ubiquitin-protein ligase UBR1
molecule tags	Metal binding protein
source organism	Saccharomyces cerevisiae
total genus	15
structure length	82
sequence length	82
chains with identical sequence	B, D, F
ec nomenclature	ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date	2010-06-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02207	zf-UBR	Putative zinc finger in N-recognin (UBR box)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.110.30	Mainly Beta	Ribbon	Cysteine Rich Protein	Cysteine Rich Protein	3nisA01

3NIMA 3NILA 3NINA 3NISA 3NIHA 3NIKA 3NIJA
chains in the Genus database with same CATH superfamily

2L4ZA 2O10A 2DFYC 2IYBE 2XQNT 2DARA 1X6AA 1IBIA 3NINA 2LXDA 3ZPOA 4HI8B 2CU8A 5FXXA 4EZHA 1X63A 3AVSA 1QLIA 1CXXA 3NIHA 2CUPA 3NIKA 2YPAC 5FY0A 4EZ4A 1X4LA 1X68A 1WIGA 4UF0B 2O13A 2MBVA 1RUTX 4KFZA 3ZLIA 3MMKA 2EHEA 2LZUA 3AVRA 1NYPA 1X3HA 2L6ZC 4UF0A 2XJZA 1V6GA 1IMLA 2CO8A 2XJYA 5FY7A 5FYMA 4HI9B 5LKXA 4ASKA 2D8XA 2D8ZA 1U5SB 2MIUA 5LKZA 5FP3A 5FXZA 4BHWA 3F6QB 1J2OA 4EYUA 2L6YB 1X64A 2CUQA 2JTNA 2CORA 1WYHA 2CURA 2DJ7A 5LKTA 5A1LA 3NIJA 1M3VA 1A7IA 5FXVA 2KBXB 5LKUA 3NILA 1CTLA 3NIMA 3IXEB 2EGQA 1B8TA 5FXWA 2D8YA 5FY1A 1X62A 2DLOA 1X61A 1G47A 3NISA 4JCJA 2XUEA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3NIM A;  3NIL A;  3NIN A;  3NIS A;  3NIH A;  3NIK A;  3NIJ A; 
#chains in the Genus database with same CATH topology
 2L4Z A;  2O10 A;  2DFY C;  2IYB E;  2XQN T;  2DAR A;  1X6A A;  1IBI A;  3NIN A;  2LXD A;  3ZPO A;  4HI8 B;  2CU8 A;  5FXX A;  4EZH A;  1X63 A;  3AVS A;  1QLI A;  1CXX A;  3NIH A;  2CUP A;  3NIK A;  2YPA C;  5FY0 A;  4EZ4 A;  1X4L A;  1X68 A;  1WIG A;  4UF0 B;  2O13 A;  2MBV A;  1RUT X;  4KFZ A;  3ZLI A;  3MMK A;  2EHE A;  2LZU A;  3AVR A;  1NYP A;  1X3H A;  2L6Z C;  4UF0 A;  2XJZ A;  1V6G A;  1IML A;  2CO8 A;  2XJY A;  5FY7 A;  5FYM A;  4HI9 B;  5LKX A;  4ASK A;  2D8X A;  2D8Z A;  1U5S B;  2MIU A;  5LKZ A;  5FP3 A;  5FXZ A;  4BHW A;  3F6Q B;  1J2O A;  4EYU A;  2L6Y B;  1X64 A;  2CUQ A;  2JTN A;  2COR A;  1WYH A;  2CUR A;  2DJ7 A;  5LKT A;  5A1L A;  3NIJ A;  1M3V A;  1A7I A;  5FXV A;  2KBX B;  5LKU A;  3NIL A;  1CTL A;  3NIM A;  3IXE B;  2EGQ A;  1B8T A;  5FXW A;  2D8Y A;  5FY1 A;  1X62 A;  2DLO A;  1X61 A;  1G47 A;  3NIS A;  4JCJ A;  2XUE A; 
#chains in the Genus database with same CATH homology
 2L4Z A;  2O10 A;  2DFY C;  2IYB E;  2XQN T;  2DAR A;  1X6A A;  1IBI A;  3NIN A;  2LXD A;  3ZPO A;  4HI8 B;  2CU8 A;  5FXX A;  4EZH A;  1X63 A;  3AVS A;  1QLI A;  1CXX A;  3NIH A;  2CUP A;  3NIK A;  2YPA C;  5FY0 A;  4EZ4 A;  1X4L A;  1X68 A;  1WIG A;  4UF0 B;  2O13 A;  2MBV A;  1RUT X;  4KFZ A;  3ZLI A;  3MMK A;  2EHE A;  2LZU A;  3AVR A;  1NYP A;  1X3H A;  2L6Z C;  4UF0 A;  2XJZ A;  1V6G A;  1IML A;  2CO8 A;  2XJY A;  5FY7 A;  5FYM A;  4HI9 B;  5LKX A;  4ASK A;  2D8X A;  2D8Z A;  1U5S B;  2MIU A;  5LKZ A;  5FP3 A;  5FXZ A;  4BHW A;  3F6Q B;  1J2O A;  4EYU A;  2L6Y B;  1X64 A;  2CUQ A;  2JTN A;  2COR A;  1WYH A;  2CUR A;  2DJ7 A;  5LKT A;  5A1L A;  3NIJ A;  1M3V A;  1A7I A;  5FXV A;  2KBX B;  5LKU A;  3NIL A;  1CTL A;  3NIM A;  3IXE B;  2EGQ A;  1B8T A;  5FXW A;  2D8Y A;  5FY1 A;  1X62 A;  2DLO A;  1X61 A;  1G47 A;  3NIS A;  4JCJ A;  2XUE A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3NISA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations