3NIS | Genus

Total Genus 15

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	15
sequence length	82
structure length	82
Chain Sequence	GSVHKHTGRNCGRKFKIGEPLYRCHECGCDDTCVLCIHCFNPKDHVNHHVCTDICTEFTSGICDCGDEEAWNSPLHCKAEEQ

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

publication title	Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases pubmed doi rcsb
molecule keywords	E3 ubiquitin-protein ligase UBR1
molecule tags	Metal binding protein
source organism	Saccharomyces cerevisiae
total genus	15
structure length	82
sequence length	82
chains with identical sequence	B, D, F
ec nomenclature	ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date	2010-06-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02207	zf-UBR	Putative zinc finger in N-recognin (UBR box)

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.10.110.30	Mainly Beta	Ribbon	Cysteine Rich Protein	Cysteine Rich Protein	3nisA01

3NIJA 3NISA 3NIMA 3NIHA 3NINA 3NIKA 3NILA
chains in the Genus database with same CATH superfamily

5FYMA 2YPAC 4HI9B 2EHEA 4UF0A 3NIHA 3NIKA 2XJZA 2D8XA 1NYPA 5FXXA 1X6AA 5FXZA 2CORA 1X64A 2IYBE 1X61A 5FXWA 1X63A 3AVRA 1X4LA 1X68A 2MIUA 5FP3A 2O13A 1M3VA 3NISA 5LKZA 2LXDA 2CU8A 1IBIA 2CURA 5LKTA 1WYHA 1RUTX 1CTLA 3ZLIA 5FY1A 2O10A 2DJ7A 1G47A 3NIJA 3F6QB 1IMLA 3IXEB 3ZPOA 1X3HA 2KBXB 4ASKA 1X62A 5A1LA 5FY0A 4HI8B 2CO8A 3NILA 4UF0B 1B8TA 2CUQA 2DFYC 5FXVA 1A7IA 3NINA 2L6YB 2JTNA 4KFZA 2LZUA 5FY7A 2D8YA 1V6GA 1J2OA 2DLOA 2XQNT 4BHWA 2EGQA 5LKUA 2L6ZC 1WIGA 3AVSA 4JCJA 2XJYA 4EZHA 2D8ZA 1U5SB 2CUPA 3MMKA 3NIMA 2MBVA 1QLIA 5LKXA 2L4ZA 2XUEA 4EZ4A 4EYUA 1CXXA 2DARA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 3NIJ A;  3NIS A;  3NIM A;  3NIH A;  3NIN A;  3NIK A;  3NIL A; 
#chains in the Genus database with same CATH topology
 5FYM A;  2YPA C;  4HI9 B;  2EHE A;  4UF0 A;  3NIH A;  3NIK A;  2XJZ A;  2D8X A;  1NYP A;  5FXX A;  1X6A A;  5FXZ A;  2COR A;  1X64 A;  2IYB E;  1X61 A;  5FXW A;  1X63 A;  3AVR A;  1X4L A;  1X68 A;  2MIU A;  5FP3 A;  2O13 A;  1M3V A;  3NIS A;  5LKZ A;  2LXD A;  2CU8 A;  1IBI A;  2CUR A;  5LKT A;  1WYH A;  1RUT X;  1CTL A;  3ZLI A;  5FY1 A;  2O10 A;  2DJ7 A;  1G47 A;  3NIJ A;  3F6Q B;  1IML A;  3IXE B;  3ZPO A;  1X3H A;  2KBX B;  4ASK A;  1X62 A;  5A1L A;  5FY0 A;  4HI8 B;  2CO8 A;  3NIL A;  4UF0 B;  1B8T A;  2CUQ A;  2DFY C;  5FXV A;  1A7I A;  3NIN A;  2L6Y B;  2JTN A;  4KFZ A;  2LZU A;  5FY7 A;  2D8Y A;  1V6G A;  1J2O A;  2DLO A;  2XQN T;  4BHW A;  2EGQ A;  5LKU A;  2L6Z C;  1WIG A;  3AVS A;  4JCJ A;  2XJY A;  4EZH A;  2D8Z A;  1U5S B;  2CUP A;  3MMK A;  3NIM A;  2MBV A;  1QLI A;  5LKX A;  2L4Z A;  2XUE A;  4EZ4 A;  4EYU A;  1CXX A;  2DAR A; 
#chains in the Genus database with same CATH homology
 5FYM A;  2YPA C;  4HI9 B;  2EHE A;  4UF0 A;  3NIH A;  3NIK A;  2XJZ A;  2D8X A;  1NYP A;  5FXX A;  1X6A A;  5FXZ A;  2COR A;  1X64 A;  2IYB E;  1X61 A;  5FXW A;  1X63 A;  3AVR A;  1X4L A;  1X68 A;  2MIU A;  5FP3 A;  2O13 A;  1M3V A;  3NIS A;  5LKZ A;  2LXD A;  2CU8 A;  1IBI A;  2CUR A;  5LKT A;  1WYH A;  1RUT X;  1CTL A;  3ZLI A;  5FY1 A;  2O10 A;  2DJ7 A;  1G47 A;  3NIJ A;  3F6Q B;  1IML A;  3IXE B;  3ZPO A;  1X3H A;  2KBX B;  4ASK A;  1X62 A;  5A1L A;  5FY0 A;  4HI8 B;  2CO8 A;  3NIL A;  4UF0 B;  1B8T A;  2CUQ A;  2DFY C;  5FXV A;  1A7I A;  3NIN A;  2L6Y B;  2JTN A;  4KFZ A;  2LZU A;  5FY7 A;  2D8Y A;  1V6G A;  1J2O A;  2DLO A;  2XQN T;  4BHW A;  2EGQ A;  5LKU A;  2L6Z C;  1WIG A;  3AVS A;  4JCJ A;  2XJY A;  4EZH A;  2D8Z A;  1U5S B;  2CUP A;  3MMK A;  3NIM A;  2MBV A;  1QLI A;  5LKX A;  2L4Z A;  2XUE A;  4EZ4 A;  4EYU A;  1CXX A;  2DAR A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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3NISA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations