3OTJI

A crystal structure of trypsin complexed with bpti (bovine pancreatic trypsin inhibitor) by x-ray/neutron joint refinement
Total Genus 10
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
10
sequence length
58
structure length
58
Chain Sequence
RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray and neutron protein crystallographic analysis of the trypsin-BPTI complex.
pubmed doi rcsb
molecule tags Hydrolase/hydrolase inhibitor
source organism Bos taurus
molecule keywords Cationic trypsin
total genus 10
structure length 58
sequence length 58
ec nomenclature
pdb deposition date 2010-09-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
I PF00014 Kunitz_BPTI Kunitz/Bovine pancreatic trypsin inhibitor domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3otjI00
2FTLI 4Y10I 1B0CA 1CBWD 1T7CB 1JV9A 3U1JE 2LFKA 1BTIA 1AAPA 1SHPA 1KIGI 1T8LB 1BTHP 2UUYB 3AUCA 3BTFI 3BTEI 1BRCI 1OA55 2M01A 1Y62A 2TGPI 2FI5I 1TOCR 1YLDB 1BPIA 1K6UA 1P2MB 1EAWB 1DENA 1F5RI 2IJOI 1BF0A 1P2OB 3AUEA 3BTHI 3BTGI 1DEMA 2DDJA 2RA3C 3AUDA 3AUHA 4WWYC 4Y11I 2LFLA 2FTMB 4Y0YI 3T62D 1IRHA 1QLQA 2PTCI 3D65I 1BUNB 2J6DA 3BYBA 3M7QB 1DTXA 1DTKA 1D0DB 4U30W 3AUGA 5JB5A 1BZ5A 1P2QB 2FI4I 5JB7A 3UOUB 4NTXB 7PTIA 2UUXA 1LD5A 1MTND 1F7ZI 1JC6A 1KUNA 2DDIA 2R9PE 4BNRI 3P92E 2ODYE 2FI3I 1ADZA 3GYMI 3UIRC 1CO7I 1EJMB 2JOTA 1OA65 5C67C 1PITA 3TPII 9PTIA 2KAII 5JB6A 1T8OB 2KCRA 1FANA 4Y0ZI 3TGII 2TPII 1BIKA 4PTIA 3L33E 8PTIA 1BRBI 1YC0I 1T8MB 4U32X 1ZR0B 4DG4C 1D0DA 3BTMI 3OTJI 2ZVXA 2KNTA 1T8NB 3FP8I 3BTWI 1P2JI 1KNTA 1P2NB 3BTQI 4ISLB 1CA0D 1KTHA 3AUBA 3L3TE 5JB4A 1BZXI 3BTDI 1TFXC 1P2II 3OFWA 3AUIA 5PTIA 1G6XA 4BD9B 2CA7A 3FP7J 4ISNB 2ZJXA 1UUAA 3TGKI 4BQDA 4ISOB 1JV8A 1UUBA 1YLCB 1NAGA 3WNYA 1P2KI 1BPTA 4WXVC 1BHCA 3TGJI 1YKTB 3P95E 1AALA 3BTTI 1FY8I 3LDIA 6PTIA 3CI7A 1FAKI 4NTYB 1LD6A 1TAWB 1TAPA 3BTKI 2M99A 1TCPA 4DTGK 1TPAI 3LDMA 3LDJA 2HEXA 2W8XA 4NTWB 4TPII 1ZJDB 3FP6I
chains in the Genus database with same CATH superfamily
2FTLI 4Y10I 1B0CA 1CBWD 1T7CB 1JV9A 3U1JE 2LFKA 1BTIA 1AAPA 1SHPA 1KIGI 1T8LB 1BTHP 2UUYB 3AUCA 3BTFI 3BTEI 1BRCI 1OA55 2M01A 1Y62A 2TGPI 2FI5I 1TOCR 1YLDB 1BPIA 1K6UA 1P2MB 1EAWB 1DENA 1F5RI 2IJOI 1BF0A 1P2OB 3AUEA 3BTHI 3BTGI 1DEMA 2DDJA 2RA3C 3AUDA 3AUHA 4WWYC 4Y11I 2LFLA 2FTMB 4Y0YI 3T62D 1IRHA 1QLQA 2PTCI 3D65I 1BUNB 2J6DA 3BYBA 3M7QB 1DTXA 1DTKA 1D0DB 4U30W 3AUGA 5JB5A 1BZ5A 1P2QB 2FI4I 5JB7A 3UOUB 4NTXB 7PTIA 2UUXA 1LD5A 1MTND 1F7ZI 1JC6A 1KUNA 2DDIA 2R9PE 4BNRI 3P92E 2ODYE 2FI3I 1ADZA 3GYMI 3UIRC 1CO7I 1EJMB 2JOTA 1OA65 5C67C 1PITA 3TPII 9PTIA 2KAII 5JB6A 1T8OB 2KCRA 1FANA 4Y0ZI 3TGII 2TPII 1BIKA 4PTIA 3L33E 8PTIA 1BRBI 1YC0I 1T8MB 4U32X 1ZR0B 4DG4C 1D0DA 3BTMI 3OTJI 2ZVXA 2KNTA 1T8NB 3FP8I 3BTWI 1P2JI 1KNTA 1P2NB 3BTQI 4ISLB 1CA0D 1KTHA 3AUBA 3L3TE 5JB4A 1BZXI 3BTDI 1TFXC 1P2II 3OFWA 3AUIA 5PTIA 1G6XA 4BD9B 2CA7A 3FP7J 4ISNB 2ZJXA 1UUAA 3TGKI 4BQDA 4ISOB 1JV8A 1UUBA 1YLCB 1NAGA 3WNYA 1P2KI 1BPTA 4WXVC 1BHCA 3TGJI 1YKTB 3P95E 1AALA 3BTTI 1FY8I 3LDIA 6PTIA 3CI7A 1FAKI 4NTYB 1LD6A 1TAWB 1TAPA 3BTKI 2M99A 1TCPA 4DTGK 1TPAI 3LDMA 3LDJA 2HEXA 2W8XA 4NTWB 4TPII 1ZJDB 3FP6I
chains in the Genus database with same CATH topology
2FTLI 4Y10I 1B0CA 1CBWD 1T7CB 1JV9A 3U1JE 2LFKA 1BTIA 1AAPA 1SHPA 1KIGI 1T8LB 1BTHP 2UUYB 3AUCA 3BTFI 3BTEI 1BRCI 1OA55 2M01A 1Y62A 2TGPI 2FI5I 1TOCR 1YLDB 1BPIA 1K6UA 1P2MB 1EAWB 1DENA 1F5RI 2IJOI 1BF0A 1P2OB 3AUEA 3BTHI 3BTGI 1DEMA 2DDJA 2RA3C 3AUDA 3AUHA 4WWYC 4Y11I 2LFLA 2FTMB 4Y0YI 3T62D 1IRHA 1QLQA 2PTCI 3D65I 1BUNB 2J6DA 3BYBA 3M7QB 1DTXA 1DTKA 1D0DB 4U30W 3AUGA 5JB5A 1BZ5A 1P2QB 2FI4I 5JB7A 3UOUB 4NTXB 7PTIA 2UUXA 1LD5A 1MTND 1F7ZI 1JC6A 1KUNA 2DDIA 2R9PE 4BNRI 3P92E 2ODYE 2FI3I 1ADZA 3GYMI 3UIRC 1CO7I 1EJMB 2JOTA 1OA65 5C67C 1PITA 3TPII 9PTIA 2KAII 5JB6A 1T8OB 2KCRA 1FANA 4Y0ZI 3TGII 2TPII 1BIKA 4PTIA 3L33E 8PTIA 1BRBI 1YC0I 1T8MB 4U32X 1ZR0B 4DG4C 1D0DA 3BTMI 3OTJI 2ZVXA 2KNTA 1T8NB 3FP8I 3BTWI 1P2JI 1KNTA 1P2NB 3BTQI 4ISLB 1CA0D 1KTHA 3AUBA 3L3TE 5JB4A 1BZXI 3BTDI 1TFXC 1P2II 3OFWA 3AUIA 5PTIA 1G6XA 4BD9B 2CA7A 3FP7J 4ISNB 2ZJXA 1UUAA 3TGKI 4BQDA 4ISOB 1JV8A 1UUBA 1YLCB 1NAGA 3WNYA 1P2KI 1BPTA 4WXVC 1BHCA 3TGJI 1YKTB 3P95E 1AALA 3BTTI 1FY8I 3LDIA 6PTIA 3CI7A 1FAKI 4NTYB 1LD6A 1TAWB 1TAPA 3BTKI 2M99A 1TCPA 4DTGK 1TPAI 3LDMA 3LDJA 2HEXA 2W8XA 4NTWB 4TPII 1ZJDB 3FP6I
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2FTL I;  4Y10 I;  1B0C A;  1CBW D;  1T7C B;  1JV9 A;  3U1J E;  2LFK A;  1BTI A;  1AAP A;  1SHP A;  1KIG I;  1T8L B;  1BTH P;  2UUY B;  3AUC A;  3BTF I;  3BTE I;  1BRC I;  1OA5 5;  2M01 A;  1Y62 A;  2TGP I;  2FI5 I;  1TOC R;  1YLD B;  1BPI A;  1K6U A;  1P2M B;  1EAW B;  1DEN A;  1F5R I;  2IJO I;  1BF0 A;  1P2O B;  3AUE A;  3BTH I;  3BTG I;  1DEM A;  2DDJ A;  2RA3 C;  3AUD A;  3AUH A;  4WWY C;  4Y11 I;  2LFL A;  2FTM B;  4Y0Y I;  3T62 D;  1IRH A;  1QLQ A;  2PTC I;  3D65 I;  1BUN B;  2J6D A;  3BYB A;  3M7Q B;  1DTX A;  1DTK A;  1D0D B;  4U30 W;  3AUG A;  5JB5 A;  1BZ5 A;  1P2Q B;  2FI4 I;  5JB7 A;  3UOU B;  4NTX B;  7PTI A;  2UUX A;  1LD5 A;  1MTN D;  1F7Z I;  1JC6 A;  1KUN A;  2DDI A;  2R9P E;  4BNR I;  3P92 E;  2ODY E;  2FI3 I;  1ADZ A;  3GYM I;  3UIR C;  1CO7 I;  1EJM B;  2JOT A;  1OA6 5;  5C67 C;  1PIT A;  3TPI I;  9PTI A;  2KAI I;  5JB6 A;  1T8O B;  2KCR A;  1FAN A;  4Y0Z I;  3TGI I;  2TPI I;  1BIK A;  4PTI A;  3L33 E;  8PTI A;  1BRB I;  1YC0 I;  1T8M B;  4U32 X;  1ZR0 B;  4DG4 C;  1D0D A;  3BTM I;  3OTJ I;  2ZVX A;  2KNT A;  1T8N B;  3FP8 I;  3BTW I;  1P2J I;  1KNT A;  1P2N B;  3BTQ I;  4ISL B;  1CA0 D;  1KTH A;  3AUB A;  3L3T E;  5JB4 A;  1BZX I;  3BTD I;  1TFX C;  1P2I I;  3OFW A;  3AUI A;  5PTI A;  1G6X A;  4BD9 B;  2CA7 A;  3FP7 J;  4ISN B;  2ZJX A;  1UUA A;  3TGK I;  4BQD A;  4ISO B;  1JV8 A;  1UUB A;  1YLC B;  1NAG A;  3WNY A;  1P2K I;  1BPT A;  4WXV C;  1BHC A;  3TGJ I;  1YKT B;  3P95 E;  1AAL A;  3BTT I;  1FY8 I;  3LDI A;  6PTI A;  3CI7 A;  1FAK I;  4NTY B;  1LD6 A;  1TAW B;  1TAP A;  3BTK I;  2M99 A;  1TCP A;  4DTG K;  1TPA I;  3LDM A;  3LDJ A;  2HEX A;  2W8X A;  4NTW B;  4TPI I;  1ZJD B;  3FP6 I; 
#chains in the Genus database with same CATH topology
 2FTL I;  4Y10 I;  1B0C A;  1CBW D;  1T7C B;  1JV9 A;  3U1J E;  2LFK A;  1BTI A;  1AAP A;  1SHP A;  1KIG I;  1T8L B;  1BTH P;  2UUY B;  3AUC A;  3BTF I;  3BTE I;  1BRC I;  1OA5 5;  2M01 A;  1Y62 A;  2TGP I;  2FI5 I;  1TOC R;  1YLD B;  1BPI A;  1K6U A;  1P2M B;  1EAW B;  1DEN A;  1F5R I;  2IJO I;  1BF0 A;  1P2O B;  3AUE A;  3BTH I;  3BTG I;  1DEM A;  2DDJ A;  2RA3 C;  3AUD A;  3AUH A;  4WWY C;  4Y11 I;  2LFL A;  2FTM B;  4Y0Y I;  3T62 D;  1IRH A;  1QLQ A;  2PTC I;  3D65 I;  1BUN B;  2J6D A;  3BYB A;  3M7Q B;  1DTX A;  1DTK A;  1D0D B;  4U30 W;  3AUG A;  5JB5 A;  1BZ5 A;  1P2Q B;  2FI4 I;  5JB7 A;  3UOU B;  4NTX B;  7PTI A;  2UUX A;  1LD5 A;  1MTN D;  1F7Z I;  1JC6 A;  1KUN A;  2DDI A;  2R9P E;  4BNR I;  3P92 E;  2ODY E;  2FI3 I;  1ADZ A;  3GYM I;  3UIR C;  1CO7 I;  1EJM B;  2JOT A;  1OA6 5;  5C67 C;  1PIT A;  3TPI I;  9PTI A;  2KAI I;  5JB6 A;  1T8O B;  2KCR A;  1FAN A;  4Y0Z I;  3TGI I;  2TPI I;  1BIK A;  4PTI A;  3L33 E;  8PTI A;  1BRB I;  1YC0 I;  1T8M B;  4U32 X;  1ZR0 B;  4DG4 C;  1D0D A;  3BTM I;  3OTJ I;  2ZVX A;  2KNT A;  1T8N B;  3FP8 I;  3BTW I;  1P2J I;  1KNT A;  1P2N B;  3BTQ I;  4ISL B;  1CA0 D;  1KTH A;  3AUB A;  3L3T E;  5JB4 A;  1BZX I;  3BTD I;  1TFX C;  1P2I I;  3OFW A;  3AUI A;  5PTI A;  1G6X A;  4BD9 B;  2CA7 A;  3FP7 J;  4ISN B;  2ZJX A;  1UUA A;  3TGK I;  4BQD A;  4ISO B;  1JV8 A;  1UUB A;  1YLC B;  1NAG A;  3WNY A;  1P2K I;  1BPT A;  4WXV C;  1BHC A;  3TGJ I;  1YKT B;  3P95 E;  1AAL A;  3BTT I;  1FY8 I;  3LDI A;  6PTI A;  3CI7 A;  1FAK I;  4NTY B;  1LD6 A;  1TAW B;  1TAP A;  3BTK I;  2M99 A;  1TCP A;  4DTG K;  1TPA I;  3LDM A;  3LDJ A;  2HEX A;  2W8X A;  4NTW B;  4TPI I;  1ZJD B;  3FP6 I; 
#chains in the Genus database with same CATH homology
 2FTL I;  4Y10 I;  1B0C A;  1CBW D;  1T7C B;  1JV9 A;  3U1J E;  2LFK A;  1BTI A;  1AAP A;  1SHP A;  1KIG I;  1T8L B;  1BTH P;  2UUY B;  3AUC A;  3BTF I;  3BTE I;  1BRC I;  1OA5 5;  2M01 A;  1Y62 A;  2TGP I;  2FI5 I;  1TOC R;  1YLD B;  1BPI A;  1K6U A;  1P2M B;  1EAW B;  1DEN A;  1F5R I;  2IJO I;  1BF0 A;  1P2O B;  3AUE A;  3BTH I;  3BTG I;  1DEM A;  2DDJ A;  2RA3 C;  3AUD A;  3AUH A;  4WWY C;  4Y11 I;  2LFL A;  2FTM B;  4Y0Y I;  3T62 D;  1IRH A;  1QLQ A;  2PTC I;  3D65 I;  1BUN B;  2J6D A;  3BYB A;  3M7Q B;  1DTX A;  1DTK A;  1D0D B;  4U30 W;  3AUG A;  5JB5 A;  1BZ5 A;  1P2Q B;  2FI4 I;  5JB7 A;  3UOU B;  4NTX B;  7PTI A;  2UUX A;  1LD5 A;  1MTN D;  1F7Z I;  1JC6 A;  1KUN A;  2DDI A;  2R9P E;  4BNR I;  3P92 E;  2ODY E;  2FI3 I;  1ADZ A;  3GYM I;  3UIR C;  1CO7 I;  1EJM B;  2JOT A;  1OA6 5;  5C67 C;  1PIT A;  3TPI I;  9PTI A;  2KAI I;  5JB6 A;  1T8O B;  2KCR A;  1FAN A;  4Y0Z I;  3TGI I;  2TPI I;  1BIK A;  4PTI A;  3L33 E;  8PTI A;  1BRB I;  1YC0 I;  1T8M B;  4U32 X;  1ZR0 B;  4DG4 C;  1D0D A;  3BTM I;  3OTJ I;  2ZVX A;  2KNT A;  1T8N B;  3FP8 I;  3BTW I;  1P2J I;  1KNT A;  1P2N B;  3BTQ I;  4ISL B;  1CA0 D;  1KTH A;  3AUB A;  3L3T E;  5JB4 A;  1BZX I;  3BTD I;  1TFX C;  1P2I I;  3OFW A;  3AUI A;  5PTI A;  1G6X A;  4BD9 B;  2CA7 A;  3FP7 J;  4ISN B;  2ZJX A;  1UUA A;  3TGK I;  4BQD A;  4ISO B;  1JV8 A;  1UUB A;  1YLC B;  1NAG A;  3WNY A;  1P2K I;  1BPT A;  4WXV C;  1BHC A;  3TGJ I;  1YKT B;  3P95 E;  1AAL A;  3BTT I;  1FY8 I;  3LDI A;  6PTI A;  3CI7 A;  1FAK I;  4NTY B;  1LD6 A;  1TAW B;  1TAP A;  3BTK I;  2M99 A;  1TCP A;  4DTG K;  1TPA I;  3LDM A;  3LDJ A;  2HEX A;  2W8X A;  4NTW B;  4TPI I;  1ZJD B;  3FP6 I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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