3QN2A

Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (sv40) large t antigen dna binding domain
Total Genus 30
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
30
sequence length
127
structure length
126
Chain Sequence
KVEDPKDFPSELLSFLSHAVCSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLATFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLEHCF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure-based design of a disulfide-linked oligomeric form of the simian virus 40 (SV40) large T antigen DNA-binding domain.
pubmed doi rcsb
molecule keywords Large T antigen
molecule tags Hydrolase
source organism Simian virus 40
total genus 30
structure length 126
sequence length 127
ec nomenclature ec 3.6.4.-:
pdb deposition date 2011-02-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 3qn2A00
2ITLA 2NL8A 4ZO0A 1Z1DB 5BYGA 3QN2A 2HW0A 5D9IA 4ZQ9A 2IPRA 3QFQA 4NBPA 1L5IA 4FB3A 4FGNA 5DCXA 4LMDA 4LIFA 2FUFA 3QK2A 2TBDA 2IF9A 1L2MA 2ITJA 5CYNA 1UUTA 1TBDA 2NTCA 1M55A 4GDFA 1RZ9A
chains in the Genus database with same CATH superfamily
2ITLA 2NL8A 4ZO0A 1Z1DB 5BYGA 3DKXA 3QN2A 2HW0A 5D9IA 4ZQ9A 1KSYA 1F08A 2IPRA 1R9WA 3QFQA 4NBPA 1L5IA 4FB3A 4FGNA 5DCXA 3DKYA 4KW3A 4LMDA 4LIFA 2FUFA 3QK2A 2TBDA 4U87A 2IF9A 1L2MA 2ITJA 5CYNA 1UUTA 1TBDA 2NTCA 1M55A 4GDFA 1RZ9A 1KSXA
chains in the Genus database with same CATH topology
2ITLA 2NL8A 4ZO0A 1Z1DB 5BYGA 3DKXA 3QN2A 2HW0A 5D9IA 4ZQ9A 1KSYA 1F08A 2IPRA 1R9WA 3QFQA 4NBPA 1L5IA 4FB3A 4FGNA 5DCXA 3DKYA 4KW3A 4LMDA 4LIFA 2FUFA 3QK2A 2TBDA 4U87A 2IF9A 1L2MA 2ITJA 5CYNA 1UUTA 1TBDA 2NTCA 1M55A 4GDFA 1RZ9A 1KSXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ITL A;  2NL8 A;  4ZO0 A;  1Z1D B;  5BYG A;  3QN2 A;  2HW0 A;  5D9I A;  4ZQ9 A;  2IPR A;  3QFQ A;  4NBP A;  1L5I A;  4FB3 A;  4FGN A;  5DCX A;  4LMD A;  4LIF A;  2FUF A;  3QK2 A;  2TBD A;  2IF9 A;  1L2M A;  2ITJ A;  5CYN A;  1UUT A;  1TBD A;  2NTC A;  1M55 A;  4GDF A;  1RZ9 A; 
#chains in the Genus database with same CATH topology
 2ITL A;  2NL8 A;  4ZO0 A;  1Z1D B;  5BYG A;  3DKX A;  3QN2 A;  2HW0 A;  5D9I A;  4ZQ9 A;  1KSY A;  1F08 A;  2IPR A;  1R9W A;  3QFQ A;  4NBP A;  1L5I A;  4FB3 A;  4FGN A;  5DCX A;  3DKY A;  4KW3 A;  4LMD A;  4LIF A;  2FUF A;  3QK2 A;  2TBD A;  4U87 A;  2IF9 A;  1L2M A;  2ITJ A;  5CYN A;  1UUT A;  1TBD A;  2NTC A;  1M55 A;  4GDF A;  1RZ9 A;  1KSX A; 
#chains in the Genus database with same CATH homology
 2ITL A;  2NL8 A;  4ZO0 A;  1Z1D B;  5BYG A;  3DKX A;  3QN2 A;  2HW0 A;  5D9I A;  4ZQ9 A;  1KSY A;  1F08 A;  2IPR A;  1R9W A;  3QFQ A;  4NBP A;  1L5I A;  4FB3 A;  4FGN A;  5DCX A;  3DKY A;  4KW3 A;  4LMD A;  4LIF A;  2FUF A;  3QK2 A;  2TBD A;  4U87 A;  2IF9 A;  1L2M A;  2ITJ A;  5CYN A;  1UUT A;  1TBD A;  2NTC A;  1M55 A;  4GDF A;  1RZ9 A;  1KSX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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