3S15E

Rna polymerase ii initiation complex with a 7-nt rna
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 64
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s15E01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s15E02
2NVTE 5M5YE 4A3CE 4BBSE 5M3FE 3GTKE 1I6HE 1Y1VE 4A3EE 4QIWH 1EIKA 2Y0SH 3GTOE 5C3EE 5FLME 4AYBH 4BXXE 5IP9E 3S1NE 2PMZH 3S2DE 3I4ME 4BBRE 4A3IE 3PO2E 3HKZH 2E2HE 1TWGE 3RZOE 2B63E 3HOYE 3S1RE 1I3QE 2E2JE 1DZFA 3H3VF 3HOVE 5IYDE 4C2ME 5IYCE 1TWHE 2NVQE 1I50E 2JA8E 2NVXE 4A3LE 5M5WE 4A3KE 2YU9E 1K83E 2JA7E 2R92E 4Y7NE 3K7AE 3I4NE 3HOZE 4BY7E 4C3IE 2JA6E 5C4XE 3GTLE 3S15E 3GTQE 2JA5E 3M4OE 5FJ8E 3CQZE 4A3JE 2NVYE 4A3ME 3GTPE 3RZDE 4C3JE 3S17E 2E2IE 3GTME 3HOUE 4A3DE 5IP7E 1TWAE 4X6AE 3GTJE 3GTGE 2WAQH 1TWFE 4A3FE 1R9TE 3S1QE 4Y52E 3H0GE 5C44E 4A3GE 3S14E 1TWCE 1SFOE 5M5XE 3PO3E 4C3HE 4BY1E 2VUME 5IYBE 2R7ZE 4A93E 5C4JE 3S1ME 1WCME 3HOWE 3M3YE 3HOXE 4A3BE 2R93E 3S2HE 5M3ME 2WB1H 1Y1WE 3FKIE 3S16E
chains in the Genus database with same CATH superfamily
2NVTE 5BYHE 5M5YE 5M5XF 1SFOF 4A3CE 3PO3F 4C3HF 4BY1F 3EQLE 2VUMF 4BBSE 5C3EF 5IYBF 3DXJE 4A93F 5M3FE 5C4JF 2Y0SI 4Q4ZE 3GTKE 1I6HE 3S2DF 1Y1VE 4A3EE 1WCMF 4QIWH 3S1MF 1QKLA 3M3YF 2A6EE 3HOXF 2Y0SH 4A3BF 3GTOE 1EIKA 1SMYE 5D4CE 4A3IF 5C3EE 2R93F 5TMCE 5M3MF 3S2HF 3PO2F 5FLME 4AYBH 4G7HE 4BXXE 1Y1WF 3S1QF 1YNNK 2NVTF 3S16F 5IP9E 3S1NE 1ZYRE 3S2DE 2PMZH 4A3CF 4KN7E 3S1RF 4XSZE 2E2JF 3HOYF 3I4ME 5IYDF 5M3FF 4AYBK 4BBRE 4A3IE 4YG2E 3PO2E 3HKZH 2E2HE 1Y1VF 5D4EE 1TWGE 3RZOE 2B63E 3GTOF 3HOYE 3S1RE 2JA8F 1I3QE 2E2JE 5FLMF 1DZFA 3H3VF 2NVXF 3HOVE 2BE5E 5IYDE 3HKZK 4C2ME 4XSXE 4YFKE 5IYCE 5IP9F 4G7ZE 3S1NF 1K83F 2JA7F 1TWHE 5IPLE 4Y7NF 3I4MF 2NVQE 3K7AF 3I4NF 1I50E 3H3VG 3HOZF 2JA8E 4BBRF 2E2HF 4BXXF 2NVXE 4A3LE 5M5WE 4A3KE 2YU9E 1TWGF 5TMFE 4QIWK 3RZOF 1K83E 1YNJK 2B63F 2JA7E 5C4XF 1I3QF 2R92E 4JK1E 4Y7NE 3GTQF 3HOVF 3K7AE 3I4NE 3HOZE 4C2MF 5IYCF 4BY7E 3M4OF 2PMZK 4C3IE 1TWHF 2JA6E 2NVYF 4KMUE 4LLGE 5D4DE 2PPBE 5C4XE 1I50F 2NVQF 2O5JE 4KN4E 3GTLE 4C3JF 3S15E 3S17F 4A3LF 3GTQE 5M5WF 4A3KF 2YU9F 4A3DF 2JA5E 4OIPE 3M4OE 5FJ8E 3CQZE 4Q5SE 2R92F 2O5IE 4MQ9E 4A3JE 2NVYE 3GTJF 4LK1E 3GTGF 4ZH4E 1TWFF 4A3ME 1R9TF 3GTPE 3RZDE 4C3JE 3S17E 2E2IE 3GTME 3HOUE 4YFXE 4BY7F 4XLPE 4C3IF 4A3DE 5IP7E 2JA6F 2CW0E 1TWAE 3S14F 4LK0E 4OIRE 4X6AE 1I6VE 3GTLF 3S15F 5E17E 3GTJE 3GTGE 4MEXE 2WAQH 1HQME 1TWFE 2JA5F 4A3FE 1R9TE 4OIQE 3S1QE 4Y52E 5FJ8F 3H0GE 5C44E 4A3GE 3CQZF 2A68E 2R7ZF 4A3JF 4GZYE 3S14E 4A3MF 3GTPF 3HOWF 1TWCE 2WAQK 4YFNE 3RZDF 2E2IF 1SFOE 3GTMF 3HOUF 5M5XE 4G7OE 3PO3E 4C3HE 4BY1E 5IP7F 2VUME 2A6HE 1TWAF 5IYBE 3FKIF 2R7ZE 4A93E 5E18E 4OIOE 4X6AF 5C4JE 5M5YF 4LJZE 2KRXA 3S1ME 1WCME 4A3FF 3HOWE 4BBSF 2WB1I 3M3YE 2A69E 4Y52F 3H0GF 5C44F 4A3GF 3HOXE 4A3BE 1IW7E 4MEYE 2R93E 4XLNE 3S2HE 5M3ME 2WB1H 1I6HF 1Y1WE 3WODE 3FKIE 4A3EF 4OINE 1TWCF 3GTKF 3S16E
chains in the Genus database with same CATH topology
2NVTE 5M5YE 4A3CE 4BBSE 5M3FE 3GTKE 1I6HE 1Y1VE 4A3EE 4QIWH 1EIKA 2Y0SH 3GTOE 5C3EE 5FLME 4AYBH 4BXXE 5IP9E 3S1NE 2PMZH 3S2DE 3I4ME 4BBRE 4A3IE 3PO2E 3HKZH 2E2HE 1TWGE 3RZOE 2B63E 3HOYE 3S1RE 1I3QE 2E2JE 1DZFA 3H3VF 3HOVE 5IYDE 4C2ME 5IYCE 1TWHE 2NVQE 1I50E 2JA8E 2NVXE 4A3LE 5M5WE 4A3KE 2YU9E 1K83E 2JA7E 2R92E 4Y7NE 3K7AE 3I4NE 3HOZE 4BY7E 4C3IE 2JA6E 5C4XE 3GTLE 3S15E 3GTQE 2JA5E 3M4OE 5FJ8E 3CQZE 4A3JE 2NVYE 4A3ME 3GTPE 3RZDE 4C3JE 3S17E 2E2IE 3GTME 3HOUE 4A3DE 5IP7E 1TWAE 4X6AE 3GTJE 3GTGE 2WAQH 1TWFE 4A3FE 1R9TE 3S1QE 4Y52E 3H0GE 5C44E 4A3GE 3S14E 1TWCE 1SFOE 5M5XE 3PO3E 4C3HE 4BY1E 2VUME 5IYBE 2R7ZE 4A93E 5C4JE 3S1ME 1WCME 3HOWE 3M3YE 3HOXE 4A3BE 2R93E 3S2HE 5M3ME 2WB1H 1Y1WE 3FKIE 3S16E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2NVT E;  5M5Y E;  4A3C E;  4BBS E;  5M3F E;  3GTK E;  1I6H E;  1Y1V E;  4A3E E;  4QIW H;  1EIK A;  2Y0S H;  3GTO E;  5C3E E;  5FLM E;  4AYB H;  4BXX E;  5IP9 E;  3S1N E;  2PMZ H;  3S2D E;  3I4M E;  4BBR E;  4A3I E;  3PO2 E;  3HKZ H;  2E2H E;  1TWG E;  3RZO E;  2B63 E;  3HOY E;  3S1R E;  1I3Q E;  2E2J E;  1DZF A;  3H3V F;  3HOV E;  5IYD E;  4C2M E;  5IYC E;  1TWH E;  2NVQ E;  1I50 E;  2JA8 E;  2NVX E;  4A3L E;  5M5W E;  4A3K E;  2YU9 E;  1K83 E;  2JA7 E;  2R92 E;  4Y7N E;  3K7A E;  3I4N E;  3HOZ E;  4BY7 E;  4C3I E;  2JA6 E;  5C4X E;  3GTL E;  3S15 E;  3GTQ E;  2JA5 E;  3M4O E;  5FJ8 E;  3CQZ E;  4A3J E;  2NVY E;  4A3M E;  3GTP E;  3RZD E;  4C3J E;  3S17 E;  2E2I E;  3GTM E;  3HOU E;  4A3D E;  5IP7 E;  1TWA E;  4X6A E;  3GTJ E;  3GTG E;  2WAQ H;  1TWF E;  4A3F E;  1R9T E;  3S1Q E;  4Y52 E;  3H0G E;  5C44 E;  4A3G E;  3S14 E;  1TWC E;  1SFO E;  5M5X E;  3PO3 E;  4C3H E;  4BY1 E;  2VUM E;  5IYB E;  2R7Z E;  4A93 E;  5C4J E;  3S1M E;  1WCM E;  3HOW E;  3M3Y E;  3HOX E;  4A3B E;  2R93 E;  3S2H E;  5M3M E;  2WB1 H;  1Y1W E;  3FKI E;  3S16 E; 
#chains in the Genus database with same CATH topology
 2NVT E;  5BYH E;  5M5Y E;  5M5X F;  1SFO F;  4A3C E;  3PO3 F;  4C3H F;  4BY1 F;  3EQL E;  2VUM F;  4BBS E;  5C3E F;  5IYB F;  3DXJ E;  4A93 F;  5M3F E;  5C4J F;  2Y0S I;  4Q4Z E;  3GTK E;  1I6H E;  3S2D F;  1Y1V E;  4A3E E;  1WCM F;  4QIW H;  3S1M F;  1QKL A;  3M3Y F;  2A6E E;  3HOX F;  2Y0S H;  4A3B F;  3GTO E;  1EIK A;  1SMY E;  5D4C E;  4A3I F;  5C3E E;  2R93 F;  5TMC E;  5M3M F;  3S2H F;  3PO2 F;  5FLM E;  4AYB H;  4G7H E;  4BXX E;  1Y1W F;  3S1Q F;  1YNN K;  2NVT F;  3S16 F;  5IP9 E;  3S1N E;  1ZYR E;  3S2D E;  2PMZ H;  4A3C F;  4KN7 E;  3S1R F;  4XSZ E;  2E2J F;  3HOY F;  3I4M E;  5IYD F;  5M3F F;  4AYB K;  4BBR E;  4A3I E;  4YG2 E;  3PO2 E;  3HKZ H;  2E2H E;  1Y1V F;  5D4E E;  1TWG E;  3RZO E;  2B63 E;  3GTO F;  3HOY E;  3S1R E;  2JA8 F;  1I3Q E;  2E2J E;  5FLM F;  1DZF A;  3H3V F;  2NVX F;  3HOV E;  2BE5 E;  5IYD E;  3HKZ K;  4C2M E;  4XSX E;  4YFK E;  5IYC E;  5IP9 F;  4G7Z E;  3S1N F;  1K83 F;  2JA7 F;  1TWH E;  5IPL E;  4Y7N F;  3I4M F;  2NVQ E;  3K7A F;  3I4N F;  1I50 E;  3H3V G;  3HOZ F;  2JA8 E;  4BBR F;  2E2H F;  4BXX F;  2NVX E;  4A3L E;  5M5W E;  4A3K E;  2YU9 E;  1TWG F;  5TMF E;  4QIW K;  3RZO F;  1K83 E;  1YNJ K;  2B63 F;  2JA7 E;  5C4X F;  1I3Q F;  2R92 E;  4JK1 E;  4Y7N E;  3GTQ F;  3HOV F;  3K7A E;  3I4N E;  3HOZ E;  4C2M F;  5IYC F;  4BY7 E;  3M4O F;  2PMZ K;  4C3I E;  1TWH F;  2JA6 E;  2NVY F;  4KMU E;  4LLG E;  5D4D E;  2PPB E;  5C4X E;  1I50 F;  2NVQ F;  2O5J E;  4KN4 E;  3GTL E;  4C3J F;  3S15 E;  3S17 F;  4A3L F;  3GTQ E;  5M5W F;  4A3K F;  2YU9 F;  4A3D F;  2JA5 E;  4OIP E;  3M4O E;  5FJ8 E;  3CQZ E;  4Q5S E;  2R92 F;  2O5I E;  4MQ9 E;  4A3J E;  2NVY E;  3GTJ F;  4LK1 E;  3GTG F;  4ZH4 E;  1TWF F;  4A3M E;  1R9T F;  3GTP E;  3RZD E;  4C3J E;  3S17 E;  2E2I E;  3GTM E;  3HOU E;  4YFX E;  4BY7 F;  4XLP E;  4C3I F;  4A3D E;  5IP7 E;  2JA6 F;  2CW0 E;  1TWA E;  3S14 F;  4LK0 E;  4OIR E;  4X6A E;  1I6V E;  3GTL F;  3S15 F;  5E17 E;  3GTJ E;  3GTG E;  4MEX E;  2WAQ H;  1HQM E;  1TWF E;  2JA5 F;  4A3F E;  1R9T E;  4OIQ E;  3S1Q E;  4Y52 E;  5FJ8 F;  3H0G E;  5C44 E;  4A3G E;  3CQZ F;  2A68 E;  2R7Z F;  4A3J F;  4GZY E;  3S14 E;  4A3M F;  3GTP F;  3HOW F;  1TWC E;  2WAQ K;  4YFN E;  3RZD F;  2E2I F;  1SFO E;  3GTM F;  3HOU F;  5M5X E;  4G7O E;  3PO3 E;  4C3H E;  4BY1 E;  5IP7 F;  2VUM E;  2A6H E;  1TWA F;  5IYB E;  3FKI F;  2R7Z E;  4A93 E;  5E18 E;  4OIO E;  4X6A F;  5C4J E;  5M5Y F;  4LJZ E;  2KRX A;  3S1M E;  1WCM E;  4A3F F;  3HOW E;  4BBS F;  2WB1 I;  3M3Y E;  2A69 E;  4Y52 F;  3H0G F;  5C44 F;  4A3G F;  3HOX E;  4A3B E;  1IW7 E;  4MEY E;  2R93 E;  4XLN E;  3S2H E;  5M3M E;  2WB1 H;  1I6H F;  1Y1W E;  3WOD E;  3FKI E;  4A3E F;  4OIN E;  1TWC F;  3GTK F;  3S16 E; 
#chains in the Genus database with same CATH homology
 2NVT E;  5M5Y E;  4A3C E;  4BBS E;  5M3F E;  3GTK E;  1I6H E;  1Y1V E;  4A3E E;  4QIW H;  1EIK A;  2Y0S H;  3GTO E;  5C3E E;  5FLM E;  4AYB H;  4BXX E;  5IP9 E;  3S1N E;  2PMZ H;  3S2D E;  3I4M E;  4BBR E;  4A3I E;  3PO2 E;  3HKZ H;  2E2H E;  1TWG E;  3RZO E;  2B63 E;  3HOY E;  3S1R E;  1I3Q E;  2E2J E;  1DZF A;  3H3V F;  3HOV E;  5IYD E;  4C2M E;  5IYC E;  1TWH E;  2NVQ E;  1I50 E;  2JA8 E;  2NVX E;  4A3L E;  5M5W E;  4A3K E;  2YU9 E;  1K83 E;  2JA7 E;  2R92 E;  4Y7N E;  3K7A E;  3I4N E;  3HOZ E;  4BY7 E;  4C3I E;  2JA6 E;  5C4X E;  3GTL E;  3S15 E;  3GTQ E;  2JA5 E;  3M4O E;  5FJ8 E;  3CQZ E;  4A3J E;  2NVY E;  4A3M E;  3GTP E;  3RZD E;  4C3J E;  3S17 E;  2E2I E;  3GTM E;  3HOU E;  4A3D E;  5IP7 E;  1TWA E;  4X6A E;  3GTJ E;  3GTG E;  2WAQ H;  1TWF E;  4A3F E;  1R9T E;  3S1Q E;  4Y52 E;  3H0G E;  5C44 E;  4A3G E;  3S14 E;  1TWC E;  1SFO E;  5M5X E;  3PO3 E;  4C3H E;  4BY1 E;  2VUM E;  5IYB E;  2R7Z E;  4A93 E;  5C4J E;  3S1M E;  1WCM E;  3HOW E;  3M3Y E;  3HOX E;  4A3B E;  2R93 E;  3S2H E;  5M3M E;  2WB1 H;  1Y1W E;  3FKI E;  3S16 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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