3S1ME

Rna polymerase ii initiation complex with a 5-nt rna (variant 1)
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 64
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s1mE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s1mE02
1SFOE 4A3GE 5M5YE 3GTOE 3GTME 4A3EE 4C3JE 5IP9E 3PO3E 1R9TE 3HOWE 5M5WE 3GTGE 3S1NE 3K7AE 2E2JE 4C2ME 2R93E 4A3FE 3H3VF 2B63E 5M5XE 4BY7E 3RZOE 5IYCE 3PO2E 2NVQE 3GTJE 3S15E 1TWGE 4A3KE 3S16E 5IYDE 3HOUE 4BBRE 5C4JE 4X6AE 2Y0SH 3CQZE 1I3QE 5IYBE 5M3ME 3GTKE 2JA5E 3I4ME 3FKIE 3S2HE 4BBSE 2JA7E 3S1ME 4A3ME 4A3BE 2WB1H 4A3DE 3S1RE 4C3HE 4A3CE 4AYBH 1TWHE 3HOVE 1DZFA 3S1QE 5FLME 3H0GE 2JA8E 4A93E 4Y52E 2YU9E 1I6HE 2NVTE 1WCME 2E2HE 1EIKA 4A3LE 2WAQH 3GTLE 1TWFE 3I4NE 1K83E 5FJ8E 3S2DE 2NVYE 3GTQE 3S17E 5M3FE 2JA6E 5C4XE 4A3IE 4QIWH 2E2IE 2PMZH 5C44E 3RZDE 3M3YE 5C3EE 1TWCE 3HKZH 3GTPE 4C3IE 4BXXE 4BY1E 2VUME 3M4OE 1Y1WE 4A3JE 5IP7E 1Y1VE 3HOXE 2NVXE 3HOYE 3HOZE 4Y7NE 2R92E 2R7ZE 3S14E 1TWAE 1I50E
chains in the Genus database with same CATH superfamily
4A3BF 1SFOE 1YNNK 4A3GE 2A6HE 5M5YE 4XLNE 3GTOE 3GTME 2A6EE 4YFKE 4A3EE 4C3JE 5IP9E 3PO3E 1R9TE 3HOWE 5M5WE 3GTGE 3S1NE 3K7AE 2E2JE 4LK1E 4KN4E 4QIWK 4MEXE 4A3DF 4C2ME 5FJ8F 2O5JE 2R93E 4A3FE 4C3HF 4A3CF 3H3VF 1ZYRE 2B63E 3DXJE 5D4DE 5M5XE 1TWHF 3HOVF 4BY7E 3RZOE 5IYCE 3PO2E 1I6VE 4OIRE 5FLMF 2NVQE 3H0GF 2Y0SI 3S1QF 4Q4ZE 3GTJE 3S15E 4A3MF 2JA8F 1TWGE 4A93F 4Y52F 4A3KE 3S16E 5IYDE 4MEYE 2YU9F 4OINE 4OIOE 3HOUE 4YFXE 4BBRE 3HOWF 5C4JE 5BYHE 2CW0E 3EQLE 1I6HF 2NVTF 1WCMF 1Y1WF 2E2HF 4X6AE 1HQME 2Y0SH 4A3LF 3CQZE 3HOXF 4YG2E 1I3QE 5IYBE 4XLPE 3GTLF 5M3ME 4GZYE 1TWFF 3GTKE 2JA5E 3I4ME 2KRXA 3FKIE 3S2HE 4BBSE 2JA7E 3S1ME 4A3ME 1K83F 4A3BE 4YFNE 3I4NF 3S14F 3S2DF 5E17E 4JK1E 2NVYF 4Q5SE 3GTQF 3S17F 5M3FF 1SFOF 2JA6F 5C4XF 5E18E 4A3IF 2WB1H 2E2IF 4A3DE 5C44F 3S1RE 3RZDF 5M5WF 3M3YF 4C3HE 4A3CE 5C3EF 4G7ZE 1TWCF 4AYBH 4C2MF 1TWHE 3HOVE 3GTPF 1DZFA 4C3IF 4BXXF 3S1QE 5FLME 3H0GE 4G7HE 2JA8E 4BY1F 2VUMF 4A93E 2WB1I 3M4OF 4Y52E 4A3JF 4G7OE 2YU9E 5TMFE 1Y1VF 5IP7F 2NVXF 5D4EE 3HOYF 3I4MF 3HOZF 4Y7NF 2R92F 3H3VG 3WODE 1I6HE 2BE5E 4OIQE 1TWAF 1YNJK 2R7ZF 2NVTE 1IW7E 1WCME 1I50F 2E2HE 2PPBE 1EIKA 5TMCE 4A3GF 5M5YF 4A3LE 1QKLA 3GTOF 2WAQH 3GTMF 3GTLE 4A3EF 1TWFE 4C3JF 5IP9F 3I4NE 3PO3F 1R9TF 2WAQK 1K83E 5FJ8E 3S2DE 2JA5F 3GTGF 3K7AF 2A69E 4LK0E 2E2JF 3S1NF 2NVYE 3GTQE 3S17E 5M3FE 2R93F 4A3FF 2JA6E 4LJZE 5C4XE 2B63F 4AYBK 4A3IE 5M5XF 2O5IE 4QIWH 4KN7E 4BY7F 3RZOF 5IYCF 2E2IE 2PMZH 5C44E 2A68E 3RZDE 3PO2F 2NVQF 3M3YE 5C3EE 3GTJF 1TWCE 4XSXE 3S1RF 2PMZK 5D4CE 1TWGF 3HKZH 3S15F 3GTPE 4C3IE 4A3KF 3S16F 5IYDF 4ZH4E 4BXXE 4MQ9E 4OIPE 3HKZK 3HOUF 4XSZE 4BBRF 4LLGE 5C4JF 4BY1E 2VUME 3M4OE 1Y1WE 5IPLE 4A3JE 4KMUE 5IP7E 1Y1VE 1SMYE 3HOXE 2NVXE 4X6AF 3HOYE 3HOZE 3CQZF 1I3QF 5IYBF 4Y7NE 2R92E 5M3MF 2R7ZE 3GTKF 3S14E 1TWAE 3FKIF 3S2HF 4BBSF 2JA7F 3S1MF 1I50E
chains in the Genus database with same CATH topology
1SFOE 4A3GE 5M5YE 3GTOE 3GTME 4A3EE 4C3JE 5IP9E 3PO3E 1R9TE 3HOWE 5M5WE 3GTGE 3S1NE 3K7AE 2E2JE 4C2ME 2R93E 4A3FE 3H3VF 2B63E 5M5XE 4BY7E 3RZOE 5IYCE 3PO2E 2NVQE 3GTJE 3S15E 1TWGE 4A3KE 3S16E 5IYDE 3HOUE 4BBRE 5C4JE 4X6AE 2Y0SH 3CQZE 1I3QE 5IYBE 5M3ME 3GTKE 2JA5E 3I4ME 3FKIE 3S2HE 4BBSE 2JA7E 3S1ME 4A3ME 4A3BE 2WB1H 4A3DE 3S1RE 4C3HE 4A3CE 4AYBH 1TWHE 3HOVE 1DZFA 3S1QE 5FLME 3H0GE 2JA8E 4A93E 4Y52E 2YU9E 1I6HE 2NVTE 1WCME 2E2HE 1EIKA 4A3LE 2WAQH 3GTLE 1TWFE 3I4NE 1K83E 5FJ8E 3S2DE 2NVYE 3GTQE 3S17E 5M3FE 2JA6E 5C4XE 4A3IE 4QIWH 2E2IE 2PMZH 5C44E 3RZDE 3M3YE 5C3EE 1TWCE 3HKZH 3GTPE 4C3IE 4BXXE 4BY1E 2VUME 3M4OE 1Y1WE 4A3JE 5IP7E 1Y1VE 3HOXE 2NVXE 3HOYE 3HOZE 4Y7NE 2R92E 2R7ZE 3S14E 1TWAE 1I50E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1SFO E;  4A3G E;  5M5Y E;  3GTO E;  3GTM E;  4A3E E;  4C3J E;  5IP9 E;  3PO3 E;  1R9T E;  3HOW E;  5M5W E;  3GTG E;  3S1N E;  3K7A E;  2E2J E;  4C2M E;  2R93 E;  4A3F E;  3H3V F;  2B63 E;  5M5X E;  4BY7 E;  3RZO E;  5IYC E;  3PO2 E;  2NVQ E;  3GTJ E;  3S15 E;  1TWG E;  4A3K E;  3S16 E;  5IYD E;  3HOU E;  4BBR E;  5C4J E;  4X6A E;  2Y0S H;  3CQZ E;  1I3Q E;  5IYB E;  5M3M E;  3GTK E;  2JA5 E;  3I4M E;  3FKI E;  3S2H E;  4BBS E;  2JA7 E;  3S1M E;  4A3M E;  4A3B E;  2WB1 H;  4A3D E;  3S1R E;  4C3H E;  4A3C E;  4AYB H;  1TWH E;  3HOV E;  1DZF A;  3S1Q E;  5FLM E;  3H0G E;  2JA8 E;  4A93 E;  4Y52 E;  2YU9 E;  1I6H E;  2NVT E;  1WCM E;  2E2H E;  1EIK A;  4A3L E;  2WAQ H;  3GTL E;  1TWF E;  3I4N E;  1K83 E;  5FJ8 E;  3S2D E;  2NVY E;  3GTQ E;  3S17 E;  5M3F E;  2JA6 E;  5C4X E;  4A3I E;  4QIW H;  2E2I E;  2PMZ H;  5C44 E;  3RZD E;  3M3Y E;  5C3E E;  1TWC E;  3HKZ H;  3GTP E;  4C3I E;  4BXX E;  4BY1 E;  2VUM E;  3M4O E;  1Y1W E;  4A3J E;  5IP7 E;  1Y1V E;  3HOX E;  2NVX E;  3HOY E;  3HOZ E;  4Y7N E;  2R92 E;  2R7Z E;  3S14 E;  1TWA E;  1I50 E; 
#chains in the Genus database with same CATH topology
 4A3B F;  1SFO E;  1YNN K;  4A3G E;  2A6H E;  5M5Y E;  4XLN E;  3GTO E;  3GTM E;  2A6E E;  4YFK E;  4A3E E;  4C3J E;  5IP9 E;  3PO3 E;  1R9T E;  3HOW E;  5M5W E;  3GTG E;  3S1N E;  3K7A E;  2E2J E;  4LK1 E;  4KN4 E;  4QIW K;  4MEX E;  4A3D F;  4C2M E;  5FJ8 F;  2O5J E;  2R93 E;  4A3F E;  4C3H F;  4A3C F;  3H3V F;  1ZYR E;  2B63 E;  3DXJ E;  5D4D E;  5M5X E;  1TWH F;  3HOV F;  4BY7 E;  3RZO E;  5IYC E;  3PO2 E;  1I6V E;  4OIR E;  5FLM F;  2NVQ E;  3H0G F;  2Y0S I;  3S1Q F;  4Q4Z E;  3GTJ E;  3S15 E;  4A3M F;  2JA8 F;  1TWG E;  4A93 F;  4Y52 F;  4A3K E;  3S16 E;  5IYD E;  4MEY E;  2YU9 F;  4OIN E;  4OIO E;  3HOU E;  4YFX E;  4BBR E;  3HOW F;  5C4J E;  5BYH E;  2CW0 E;  3EQL E;  1I6H F;  2NVT F;  1WCM F;  1Y1W F;  2E2H F;  4X6A E;  1HQM E;  2Y0S H;  4A3L F;  3CQZ E;  3HOX F;  4YG2 E;  1I3Q E;  5IYB E;  4XLP E;  3GTL F;  5M3M E;  4GZY E;  1TWF F;  3GTK E;  2JA5 E;  3I4M E;  2KRX A;  3FKI E;  3S2H E;  4BBS E;  2JA7 E;  3S1M E;  4A3M E;  1K83 F;  4A3B E;  4YFN E;  3I4N F;  3S14 F;  3S2D F;  5E17 E;  4JK1 E;  2NVY F;  4Q5S E;  3GTQ F;  3S17 F;  5M3F F;  1SFO F;  2JA6 F;  5C4X F;  5E18 E;  4A3I F;  2WB1 H;  2E2I F;  4A3D E;  5C44 F;  3S1R E;  3RZD F;  5M5W F;  3M3Y F;  4C3H E;  4A3C E;  5C3E F;  4G7Z E;  1TWC F;  4AYB H;  4C2M F;  1TWH E;  3HOV E;  3GTP F;  1DZF A;  4C3I F;  4BXX F;  3S1Q E;  5FLM E;  3H0G E;  4G7H E;  2JA8 E;  4BY1 F;  2VUM F;  4A93 E;  2WB1 I;  3M4O F;  4Y52 E;  4A3J F;  4G7O E;  2YU9 E;  5TMF E;  1Y1V F;  5IP7 F;  2NVX F;  5D4E E;  3HOY F;  3I4M F;  3HOZ F;  4Y7N F;  2R92 F;  3H3V G;  3WOD E;  1I6H E;  2BE5 E;  4OIQ E;  1TWA F;  1YNJ K;  2R7Z F;  2NVT E;  1IW7 E;  1WCM E;  1I50 F;  2E2H E;  2PPB E;  1EIK A;  5TMC E;  4A3G F;  5M5Y F;  4A3L E;  1QKL A;  3GTO F;  2WAQ H;  3GTM F;  3GTL E;  4A3E F;  1TWF E;  4C3J F;  5IP9 F;  3I4N E;  3PO3 F;  1R9T F;  2WAQ K;  1K83 E;  5FJ8 E;  3S2D E;  2JA5 F;  3GTG F;  3K7A F;  2A69 E;  4LK0 E;  2E2J F;  3S1N F;  2NVY E;  3GTQ E;  3S17 E;  5M3F E;  2R93 F;  4A3F F;  2JA6 E;  4LJZ E;  5C4X E;  2B63 F;  4AYB K;  4A3I E;  5M5X F;  2O5I E;  4QIW H;  4KN7 E;  4BY7 F;  3RZO F;  5IYC F;  2E2I E;  2PMZ H;  5C44 E;  2A68 E;  3RZD E;  3PO2 F;  2NVQ F;  3M3Y E;  5C3E E;  3GTJ F;  1TWC E;  4XSX E;  3S1R F;  2PMZ K;  5D4C E;  1TWG F;  3HKZ H;  3S15 F;  3GTP E;  4C3I E;  4A3K F;  3S16 F;  5IYD F;  4ZH4 E;  4BXX E;  4MQ9 E;  4OIP E;  3HKZ K;  3HOU F;  4XSZ E;  4BBR F;  4LLG E;  5C4J F;  4BY1 E;  2VUM E;  3M4O E;  1Y1W E;  5IPL E;  4A3J E;  4KMU E;  5IP7 E;  1Y1V E;  1SMY E;  3HOX E;  2NVX E;  4X6A F;  3HOY E;  3HOZ E;  3CQZ F;  1I3Q F;  5IYB F;  4Y7N E;  2R92 E;  5M3M F;  2R7Z E;  3GTK F;  3S14 E;  1TWA E;  3FKI F;  3S2H F;  4BBS F;  2JA7 F;  3S1M F;  1I50 E; 
#chains in the Genus database with same CATH homology
 1SFO E;  4A3G E;  5M5Y E;  3GTO E;  3GTM E;  4A3E E;  4C3J E;  5IP9 E;  3PO3 E;  1R9T E;  3HOW E;  5M5W E;  3GTG E;  3S1N E;  3K7A E;  2E2J E;  4C2M E;  2R93 E;  4A3F E;  3H3V F;  2B63 E;  5M5X E;  4BY7 E;  3RZO E;  5IYC E;  3PO2 E;  2NVQ E;  3GTJ E;  3S15 E;  1TWG E;  4A3K E;  3S16 E;  5IYD E;  3HOU E;  4BBR E;  5C4J E;  4X6A E;  2Y0S H;  3CQZ E;  1I3Q E;  5IYB E;  5M3M E;  3GTK E;  2JA5 E;  3I4M E;  3FKI E;  3S2H E;  4BBS E;  2JA7 E;  3S1M E;  4A3M E;  4A3B E;  2WB1 H;  4A3D E;  3S1R E;  4C3H E;  4A3C E;  4AYB H;  1TWH E;  3HOV E;  1DZF A;  3S1Q E;  5FLM E;  3H0G E;  2JA8 E;  4A93 E;  4Y52 E;  2YU9 E;  1I6H E;  2NVT E;  1WCM E;  2E2H E;  1EIK A;  4A3L E;  2WAQ H;  3GTL E;  1TWF E;  3I4N E;  1K83 E;  5FJ8 E;  3S2D E;  2NVY E;  3GTQ E;  3S17 E;  5M3F E;  2JA6 E;  5C4X E;  4A3I E;  4QIW H;  2E2I E;  2PMZ H;  5C44 E;  3RZD E;  3M3Y E;  5C3E E;  1TWC E;  3HKZ H;  3GTP E;  4C3I E;  4BXX E;  4BY1 E;  2VUM E;  3M4O E;  1Y1W E;  4A3J E;  5IP7 E;  1Y1V E;  3HOX E;  2NVX E;  3HOY E;  3HOZ E;  4Y7N E;  2R92 E;  2R7Z E;  3S14 E;  1TWA E;  1I50 E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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