3S2HE

Rna polymerase ii initiation complex with a 6-nt rna containing a 2[prime]-iodo atp
Total Genus 58
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Initiation complex structure and promoter proofreading.
pubmed doi rcsb
molecule tags Transcription/rna/dna
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 58
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2011-05-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3s2hE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3s2hE02
1TWHE 4A93E 3S14E 1Y1VE 4A3ME 2WB1H 3K7AE 5IYCE 5M3FE 3PO3E 4X6AE 3S17E 4A3FE 3FKIE 3M3YE 4C3JE 3GTME 3GTPE 4A3IE 3S1QE 2NVXE 3HOUE 1R9TE 4AYBH 1I6HE 2JA8E 2NVYE 4A3DE 2JA7E 3HOWE 1TWCE 3PO2E 2NVQE 5M5XE 3HOZE 2JA5E 2Y0SH 4A3KE 3S2DE 5FJ8E 3S15E 2WAQH 2R92E 1K83E 2B63E 4C3HE 4BXXE 4BBRE 4C3IE 5M5WE 4A3JE 2E2HE 3RZDE 3GTLE 3I4NE 5IP9E 4A3EE 5FLME 4Y52E 1I3QE 3S1ME 2E2JE 1TWGE 4Y7NE 3HOXE 4BY1E 5C4JE 2VUME 4QIWH 2NVTE 3GTJE 2YU9E 4C2ME 1DZFA 4BBSE 2E2IE 5IYDE 5IP7E 2JA6E 4A3CE 3H3VF 5M5YE 3GTOE 3HOYE 2PMZH 3I4ME 1WCME 1SFOE 3HKZH 2R7ZE 4A3BE 3H0GE 1Y1WE 4BY7E 3S2HE 5IYBE 1I50E 5M3ME 5C4XE 4A3GE 1TWFE 2R93E 1EIKA 3GTQE 3S16E 3GTGE 3S1NE 3RZOE 1TWAE 3M4OE 3S1RE 5C3EE 3GTKE 3HOVE 3CQZE 4A3LE 5C44E
chains in the Genus database with same CATH superfamily
1TWHE 4A3KF 4A93E 4GZYE 3S14E 1Y1VE 3S2DF 4A3ME 5FJ8F 2Y0SI 2R92F 1K83F 2B63F 2WB1H 4BXXF 3K7AE 5IYCE 4BBRF 4ZH4E 4C3IF 5M3FE 5M5WF 4A3JF 3PO3E 4X6AE 2E2HF 3S17E 4A3FE 4KN4E 3RZDF 3GTLF 3I4NF 3FKIE 5IP9F 3DXJE 4A3EF 3M3YE 4C3JE 3GTME 5FLMF 4Y52F 3GTPE 4G7HE 1I3QF 3H3VG 4KMUE 3S1MF 4A3IE 2KRXA 3S1QE 2E2JF 1TWGF 2NVXE 4MEYE 4XLNE 3HOUE 3HOXF 4Q4ZE 2VUMF 1R9TE 5D4DE 2NVTF 4AYBH 3GTJF 2YU9F 1I6HE 4C2MF 2JA8E 2NVYE 3HKZK 4BBSF 5IYDF 4A3DE 4OIOE 2A6EE 5IP7F 2JA6F 2JA7E 4A3CF 3HOWE 4XLPE 1TWCE 4JK1E 5M5YF 3GTOF 2O5JE 3PO2E 2NVQE 5M5XE 3HOYF 3HOZE 3I4MF 2JA5E 2Y0SH 1WCMF 2BE5E 1SFOF 4A3KE 3S2DE 5FJ8E 3S15E 1HQME 2CW0E 2R92E 2WAQH 3H0GF 4YFNE 2R7ZF 1K83E 4A3BF 5TMCE 1Y1WF 2B63E 4C3HE 4BXXE 4XSZE 4BY7F 4G7ZE 4BBRE 4MEXE 4C3IE 5M5WE 3S2HF 4A3JE 5IYBF 1I50F 2E2HE 4Q5SE 3RZDE 1I6VE 4XSXE 3GTLE 3I4NE 4G7OE 5M3MF 5IP9E 4A3EE 3PO3F 5FLME 4Y52E 4YG2E 1I3QE 2A69E 4A3GF 3S1ME 1TWFF 3FKIF 5E17E 2E2JE 2PPBE 2R93F 1TWGE 4Y7NE 3GTQF 3HOXE 5E18E 4KN7E 3S16F 4BY1E 5C4JE 2VUME 3GTGF 3S1NF 4QIWH 2NVTE 3RZOF 3GTJE 2YU9E 4C2ME 1DZFA 1SMYE 1TWAF 3M4OF 3S1RF 4BBSE 5C3EF 3GTKF 2E2IE 5IYDE 3HOVF 4YFXE 5IP7E 2JA6E 4A3CE 3H3VF 1QKLA 3CQZF 4OIRE 4A3LF 5M5YE 3GTOE 5BYHE 5C44F 5C4XF 4A3DF 1TWHF 4LK1E 4A93F 3HOYE 2PMZH 3S14F 1Y1VF 4LLGE 3I4ME 4A3MF 1WCME 1SFOE 3WODE 5M5XF 3HKZH 3K7AF 5IYCF 2R7ZE 4A3BE 5M3FF 2JA5F 3H0GE 3HOWF 4X6AF 1Y1WE 4BY7E 3S2HE 2WB1I 5D4CE 1YNJK 4A3FF 3S17F 4AYBK 5IPLE 1YNNK 3S15F 4OIQE 5IYBE 1I50E 4C3JF 3GTMF 3M3YF 3GTPF 4LJZE 4LK0E 4C3HF 5M3ME 5C4XE 4A3IF 2O5IE 4YFKE 3S1QF 2NVXF 4A3GE 4QIWK 3HOUF 1TWFE 2R93E 1EIKA 3GTQE 1R9TF 3S16E 1IW7E 1I6HF 3GTGE 3S1NE 2A68E 4OIPE 2NVYF 2JA8F 3HOZF 4Y7NF 2WAQK 3RZOE 4OINE 4BY1F 1TWAE 2JA7F 1ZYRE 5C4JF 3M4OE 3S1RE 1TWCF 5C3EE 3GTKE 2PMZK 5D4EE 4MQ9E 3HOVE 5TMFE 3PO2F 2NVQF 3CQZE 4A3LE 2A6HE 3EQLE 5C44E 2E2IF
chains in the Genus database with same CATH topology
1TWHE 4A93E 3S14E 1Y1VE 4A3ME 2WB1H 3K7AE 5IYCE 5M3FE 3PO3E 4X6AE 3S17E 4A3FE 3FKIE 3M3YE 4C3JE 3GTME 3GTPE 4A3IE 3S1QE 2NVXE 3HOUE 1R9TE 4AYBH 1I6HE 2JA8E 2NVYE 4A3DE 2JA7E 3HOWE 1TWCE 3PO2E 2NVQE 5M5XE 3HOZE 2JA5E 2Y0SH 4A3KE 3S2DE 5FJ8E 3S15E 2WAQH 2R92E 1K83E 2B63E 4C3HE 4BXXE 4BBRE 4C3IE 5M5WE 4A3JE 2E2HE 3RZDE 3GTLE 3I4NE 5IP9E 4A3EE 5FLME 4Y52E 1I3QE 3S1ME 2E2JE 1TWGE 4Y7NE 3HOXE 4BY1E 5C4JE 2VUME 4QIWH 2NVTE 3GTJE 2YU9E 4C2ME 1DZFA 4BBSE 2E2IE 5IYDE 5IP7E 2JA6E 4A3CE 3H3VF 5M5YE 3GTOE 3HOYE 2PMZH 3I4ME 1WCME 1SFOE 3HKZH 2R7ZE 4A3BE 3H0GE 1Y1WE 4BY7E 3S2HE 5IYBE 1I50E 5M3ME 5C4XE 4A3GE 1TWFE 2R93E 1EIKA 3GTQE 3S16E 3GTGE 3S1NE 3RZOE 1TWAE 3M4OE 3S1RE 5C3EE 3GTKE 3HOVE 3CQZE 4A3LE 5C44E
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TWH E;  4A93 E;  3S14 E;  1Y1V E;  4A3M E;  2WB1 H;  3K7A E;  5IYC E;  5M3F E;  3PO3 E;  4X6A E;  3S17 E;  4A3F E;  3FKI E;  3M3Y E;  4C3J E;  3GTM E;  3GTP E;  4A3I E;  3S1Q E;  2NVX E;  3HOU E;  1R9T E;  4AYB H;  1I6H E;  2JA8 E;  2NVY E;  4A3D E;  2JA7 E;  3HOW E;  1TWC E;  3PO2 E;  2NVQ E;  5M5X E;  3HOZ E;  2JA5 E;  2Y0S H;  4A3K E;  3S2D E;  5FJ8 E;  3S15 E;  2WAQ H;  2R92 E;  1K83 E;  2B63 E;  4C3H E;  4BXX E;  4BBR E;  4C3I E;  5M5W E;  4A3J E;  2E2H E;  3RZD E;  3GTL E;  3I4N E;  5IP9 E;  4A3E E;  5FLM E;  4Y52 E;  1I3Q E;  3S1M E;  2E2J E;  1TWG E;  4Y7N E;  3HOX E;  4BY1 E;  5C4J E;  2VUM E;  4QIW H;  2NVT E;  3GTJ E;  2YU9 E;  4C2M E;  1DZF A;  4BBS E;  2E2I E;  5IYD E;  5IP7 E;  2JA6 E;  4A3C E;  3H3V F;  5M5Y E;  3GTO E;  3HOY E;  2PMZ H;  3I4M E;  1WCM E;  1SFO E;  3HKZ H;  2R7Z E;  4A3B E;  3H0G E;  1Y1W E;  4BY7 E;  3S2H E;  5IYB E;  1I50 E;  5M3M E;  5C4X E;  4A3G E;  1TWF E;  2R93 E;  1EIK A;  3GTQ E;  3S16 E;  3GTG E;  3S1N E;  3RZO E;  1TWA E;  3M4O E;  3S1R E;  5C3E E;  3GTK E;  3HOV E;  3CQZ E;  4A3L E;  5C44 E; 
#chains in the Genus database with same CATH topology
 1TWH E;  4A3K F;  4A93 E;  4GZY E;  3S14 E;  1Y1V E;  3S2D F;  4A3M E;  5FJ8 F;  2Y0S I;  2R92 F;  1K83 F;  2B63 F;  2WB1 H;  4BXX F;  3K7A E;  5IYC E;  4BBR F;  4ZH4 E;  4C3I F;  5M3F E;  5M5W F;  4A3J F;  3PO3 E;  4X6A E;  2E2H F;  3S17 E;  4A3F E;  4KN4 E;  3RZD F;  3GTL F;  3I4N F;  3FKI E;  5IP9 F;  3DXJ E;  4A3E F;  3M3Y E;  4C3J E;  3GTM E;  5FLM F;  4Y52 F;  3GTP E;  4G7H E;  1I3Q F;  3H3V G;  4KMU E;  3S1M F;  4A3I E;  2KRX A;  3S1Q E;  2E2J F;  1TWG F;  2NVX E;  4MEY E;  4XLN E;  3HOU E;  3HOX F;  4Q4Z E;  2VUM F;  1R9T E;  5D4D E;  2NVT F;  4AYB H;  3GTJ F;  2YU9 F;  1I6H E;  4C2M F;  2JA8 E;  2NVY E;  3HKZ K;  4BBS F;  5IYD F;  4A3D E;  4OIO E;  2A6E E;  5IP7 F;  2JA6 F;  2JA7 E;  4A3C F;  3HOW E;  4XLP E;  1TWC E;  4JK1 E;  5M5Y F;  3GTO F;  2O5J E;  3PO2 E;  2NVQ E;  5M5X E;  3HOY F;  3HOZ E;  3I4M F;  2JA5 E;  2Y0S H;  1WCM F;  2BE5 E;  1SFO F;  4A3K E;  3S2D E;  5FJ8 E;  3S15 E;  1HQM E;  2CW0 E;  2R92 E;  2WAQ H;  3H0G F;  4YFN E;  2R7Z F;  1K83 E;  4A3B F;  5TMC E;  1Y1W F;  2B63 E;  4C3H E;  4BXX E;  4XSZ E;  4BY7 F;  4G7Z E;  4BBR E;  4MEX E;  4C3I E;  5M5W E;  3S2H F;  4A3J E;  5IYB F;  1I50 F;  2E2H E;  4Q5S E;  3RZD E;  1I6V E;  4XSX E;  3GTL E;  3I4N E;  4G7O E;  5M3M F;  5IP9 E;  4A3E E;  3PO3 F;  5FLM E;  4Y52 E;  4YG2 E;  1I3Q E;  2A69 E;  4A3G F;  3S1M E;  1TWF F;  3FKI F;  5E17 E;  2E2J E;  2PPB E;  2R93 F;  1TWG E;  4Y7N E;  3GTQ F;  3HOX E;  5E18 E;  4KN7 E;  3S16 F;  4BY1 E;  5C4J E;  2VUM E;  3GTG F;  3S1N F;  4QIW H;  2NVT E;  3RZO F;  3GTJ E;  2YU9 E;  4C2M E;  1DZF A;  1SMY E;  1TWA F;  3M4O F;  3S1R F;  4BBS E;  5C3E F;  3GTK F;  2E2I E;  5IYD E;  3HOV F;  4YFX E;  5IP7 E;  2JA6 E;  4A3C E;  3H3V F;  1QKL A;  3CQZ F;  4OIR E;  4A3L F;  5M5Y E;  3GTO E;  5BYH E;  5C44 F;  5C4X F;  4A3D F;  1TWH F;  4LK1 E;  4A93 F;  3HOY E;  2PMZ H;  3S14 F;  1Y1V F;  4LLG E;  3I4M E;  4A3M F;  1WCM E;  1SFO E;  3WOD E;  5M5X F;  3HKZ H;  3K7A F;  5IYC F;  2R7Z E;  4A3B E;  5M3F F;  2JA5 F;  3H0G E;  3HOW F;  4X6A F;  1Y1W E;  4BY7 E;  3S2H E;  2WB1 I;  5D4C E;  1YNJ K;  4A3F F;  3S17 F;  4AYB K;  5IPL E;  1YNN K;  3S15 F;  4OIQ E;  5IYB E;  1I50 E;  4C3J F;  3GTM F;  3M3Y F;  3GTP F;  4LJZ E;  4LK0 E;  4C3H F;  5M3M E;  5C4X E;  4A3I F;  2O5I E;  4YFK E;  3S1Q F;  2NVX F;  4A3G E;  4QIW K;  3HOU F;  1TWF E;  2R93 E;  1EIK A;  3GTQ E;  1R9T F;  3S16 E;  1IW7 E;  1I6H F;  3GTG E;  3S1N E;  2A68 E;  4OIP E;  2NVY F;  2JA8 F;  3HOZ F;  4Y7N F;  2WAQ K;  3RZO E;  4OIN E;  4BY1 F;  1TWA E;  2JA7 F;  1ZYR E;  5C4J F;  3M4O E;  3S1R E;  1TWC F;  5C3E E;  3GTK E;  2PMZ K;  5D4E E;  4MQ9 E;  3HOV E;  5TMF E;  3PO2 F;  2NVQ F;  3CQZ E;  4A3L E;  2A6H E;  3EQL E;  5C44 E;  2E2I F; 
#chains in the Genus database with same CATH homology
 1TWH E;  4A93 E;  3S14 E;  1Y1V E;  4A3M E;  2WB1 H;  3K7A E;  5IYC E;  5M3F E;  3PO3 E;  4X6A E;  3S17 E;  4A3F E;  3FKI E;  3M3Y E;  4C3J E;  3GTM E;  3GTP E;  4A3I E;  3S1Q E;  2NVX E;  3HOU E;  1R9T E;  4AYB H;  1I6H E;  2JA8 E;  2NVY E;  4A3D E;  2JA7 E;  3HOW E;  1TWC E;  3PO2 E;  2NVQ E;  5M5X E;  3HOZ E;  2JA5 E;  2Y0S H;  4A3K E;  3S2D E;  5FJ8 E;  3S15 E;  2WAQ H;  2R92 E;  1K83 E;  2B63 E;  4C3H E;  4BXX E;  4BBR E;  4C3I E;  5M5W E;  4A3J E;  2E2H E;  3RZD E;  3GTL E;  3I4N E;  5IP9 E;  4A3E E;  5FLM E;  4Y52 E;  1I3Q E;  3S1M E;  2E2J E;  1TWG E;  4Y7N E;  3HOX E;  4BY1 E;  5C4J E;  2VUM E;  4QIW H;  2NVT E;  3GTJ E;  2YU9 E;  4C2M E;  1DZF A;  4BBS E;  2E2I E;  5IYD E;  5IP7 E;  2JA6 E;  4A3C E;  3H3V F;  5M5Y E;  3GTO E;  3HOY E;  2PMZ H;  3I4M E;  1WCM E;  1SFO E;  3HKZ H;  2R7Z E;  4A3B E;  3H0G E;  1Y1W E;  4BY7 E;  3S2H E;  5IYB E;  1I50 E;  5M3M E;  5C4X E;  4A3G E;  1TWF E;  2R93 E;  1EIK A;  3GTQ E;  3S16 E;  3GTG E;  3S1N E;  3RZO E;  1TWA E;  3M4O E;  3S1R E;  5C3E E;  3GTK E;  3HOV E;  3CQZ E;  4A3L E;  5C44 E; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...