3V8XA

The crystal structure of transferrin binding protein a (tbpa) from neisserial meningitidis serogroup b in complex with full length human transferrin
Total Genus 225
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
225
sequence length
862
structure length
853
Chain Sequence
EVTGLGKLVKSSDTLSKEQVLNIRDLTRYDPGIAVVEQGRGASSGYSIRGMDKNRVSLTVDGVSQIQSYTAQAALGGTRTAGSSGAINEIEYENVKAVEISKGSNSVEQGSGALAGSVAFQTKTADDVIGEGRQWGIQSKTAYSGKNRGLTQSIALAGRIGGAEALLIHTGRRAGEIRAHEDAGRGVQSFNRLVPVEDSSNYAYFIVKEECKNGSYETCKANPKKDVVGKDERQTVSTRDYTGPNRFLADPLSYESRSWLFRPGFRFENKRHYIGGILEHTQQTFDTRDMTVPAFLTKAVFDANKKQAGSLPGNGKYAGNHKYGGLFTNGENGALVGAEYGTGVFYDETHTKSRYGLEYVYTNADKDTWADYARLSYDRQGVGLDNHFQQTHCSADGSDKYCRPSADKPFSYYKSDRVIYGESHRLLQAAFKKSFDKIRHNLSVNLGFDRFGSNLRHQDYYYQHANRAYSSNTPPQNNGKKISPNGSETSPYWVTIGRGNVVTGQICRLGNNTYTDCTPRSINGKSYYAAVRDNVRLGRWADVGAGLRYDYRSTHSDDGSVSTGTHRTLSWNAGIVLKPTDWLDLTYRTSTGFRLPSFAEMYGWRAGVQSKAVKIDPEKSFNKEAGIVFKGDFGNLEASWFNNAYRDLIVRGYEAQIKDGKEEAKGDPAYLNAQSARITGINILGKIDWNGVWYSTFAYNRVRVRDIKKRADRTDIQSHLFDAIQPSRYVVGLGYDQPEGKWGVNGMLTYSKAKEITELLGSRALLNGNSRNTKATARRTRPWYIVDVSGYYTVKKHFTLRAGVYNLLNYRYVTWENVRQTAGGAVNQHKNVGVYNRYAAPGRNYTFSLEYKF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for iron piracy by pathogenic Neisseria.
pubmed doi rcsb
molecule tags Membrane protein/metal transport
source organism Neisseria meningitidis serogroup b
molecule keywords Transferrin-binding protein 1
total genus 225
structure length 853
sequence length 862
ec nomenclature
pdb deposition date 2011-12-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00593 TonB_dep_Rec TonB dependent receptor
A PF07715 Plug TonB-dependent Receptor Plug Domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.170.20 Mainly Beta Beta Barrel Maltoporin; Chain A TonB-dependent receptor, beta-barrel domain 3v8xA02
2.170.130.10 Mainly Beta Beta Complex Ferric Hydroxamate Uptake Protein; Chain A, domain 1 TonB-dependent receptor, plug domain 3v8xA01
3V8XA 2FCPA 2HDFA 3DDRA 1PO3A 2W77A 4RDTA 1XKWA 2GUFA 3RGNA 1FEPA 1NQEA 5FOKA 1QJQA 1KMOA 3QLBA 3FHHA 1NQHA 2O5PA 4RDRA 2W6TA 2GRXA 2HDIA 1BY5A 2W78A 4AIQA 2GSKA 4CU4A 1PNZA 2W75A 3M8DA 3EFMA 3V89A 1KMPA 1BY3A 3RGMA 3M8BA 1XKHA 2IAHA 1QFGA 2W6UA 4EPAA 2W76A 1FCPA 1FI1A 1NQFA 1QFFA 2YSUA 3CSNA 4AIPA 1QKCA 1PO0A 1NQGA 1UJWA 3CSLA 2W16A 4B7OA
chains in the Genus database with same CATH superfamily
3V8XA 2FCPA 2HDFA 3DDRA 1PO3A 2W77A 4RDTA 1JBIA 1XKWA 2GUFA 3RGNA 1FEPA 1NQEA 5FOKA 1QJQA 1KMOA 1OH2Q 1MPOA 3QLBA 3FHHA 1NQHA 2O5PA 1MPRA 4RDRA 2W6TA 1MPQA 2GRXA 2HDIA 1MPMA 1BY5A 2W16A 2W78A 4AIQA 1OH2P 2GSKA 4CU4A 1PNZA 2W75A 1A0TP 3M8DA 3EFMA 3V89A 1KMPA 1BY3A 3RGMA 1MPNA 1MALA 3M8BA 2IAHA 1XKHA 1UJWA 1QFGA 2W6UA 1AF6A 4EPAA 2W76A 1FCPA 1FI1A 1NQFA 1QFFA 2YSUA 3CSNA 4AIPA 1QKCA 2MPRA 1NQGA 1PO0A 3CSLA 1A0SP 4B7OA
chains in the Genus database with same CATH topology
3V8XA 2FCPA 2HDFA 3DDRA 1PO3A 2W77A 4RDTA 1XKWA 2GUFA 3RGNA 1FEPA 1NQEA 5FOKA 1QJQA 1KMOA 3QLBA 3FHHA 1NQHA 2O5PA 4RDRA 2W6TA 2GRXA 2HDIA 1BY5A 2W78A 4AIQA 2GSKA 4CU4A 1PNZA 2W75A 3M8DA 3EFMA 3V89A 1KMPA 1BY3A 3RGMA 3M8BA 1XKHA 2IAHA 1QFGA 2W6UA 4EPAA 2W76A 1FCPA 1FI1A 1NQFA 1QFFA 2YSUA 3CSNA 4AIPA 1QKCA 1PO0A 1NQGA 1UJWA 3CSLA 2W16A 4B7OA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3V8X A;  2FCP A;  2HDF A;  3DDR A;  1PO3 A;  2W77 A;  4RDT A;  1XKW A;  2GUF A;  3RGN A;  1FEP A;  1NQE A;  5FOK A;  1QJQ A;  1KMO A;  3QLB A;  3FHH A;  1NQH A;  2O5P A;  4RDR A;  2W6T A;  2GRX A;  2HDI A;  1BY5 A;  2W78 A;  4AIQ A;  2GSK A;  4CU4 A;  1PNZ A;  2W75 A;  3M8D A;  3EFM A;  3V89 A;  1KMP A;  1BY3 A;  3RGM A;  3M8B A;  1XKH A;  2IAH A;  1QFG A;  2W6U A;  4EPA A;  2W76 A;  1FCP A;  1FI1 A;  1NQF A;  1QFF A;  2YSU A;  3CSN A;  4AIP A;  1QKC A;  1PO0 A;  1NQG A;  1UJW A;  3CSL A;  2W16 A;  4B7O A; 
#chains in the Genus database with same CATH topology
 3V8X A;  2FCP A;  2HDF A;  3DDR A;  1PO3 A;  2W77 A;  4RDT A;  1JBI A;  1XKW A;  2GUF A;  3RGN A;  1FEP A;  1NQE A;  5FOK A;  1QJQ A;  1KMO A;  1OH2 Q;  1MPO A;  3QLB A;  3FHH A;  1NQH A;  2O5P A;  1MPR A;  4RDR A;  2W6T A;  1MPQ A;  2GRX A;  2HDI A;  1MPM A;  1BY5 A;  2W16 A;  2W78 A;  4AIQ A;  1OH2 P;  2GSK A;  4CU4 A;  1PNZ A;  2W75 A;  1A0T P;  3M8D A;  3EFM A;  3V89 A;  1KMP A;  1BY3 A;  3RGM A;  1MPN A;  1MAL A;  3M8B A;  2IAH A;  1XKH A;  1UJW A;  1QFG A;  2W6U A;  1AF6 A;  4EPA A;  2W76 A;  1FCP A;  1FI1 A;  1NQF A;  1QFF A;  2YSU A;  3CSN A;  4AIP A;  1QKC A;  2MPR A;  1NQG A;  1PO0 A;  3CSL A;  1A0S P;  4B7O A; 
#chains in the Genus database with same CATH homology
 3V8X A;  2FCP A;  2HDF A;  3DDR A;  1PO3 A;  2W77 A;  4RDT A;  1XKW A;  2GUF A;  3RGN A;  1FEP A;  1NQE A;  5FOK A;  1QJQ A;  1KMO A;  3QLB A;  3FHH A;  1NQH A;  2O5P A;  4RDR A;  2W6T A;  2GRX A;  2HDI A;  1BY5 A;  2W78 A;  4AIQ A;  2GSK A;  4CU4 A;  1PNZ A;  2W75 A;  3M8D A;  3EFM A;  3V89 A;  1KMP A;  1BY3 A;  3RGM A;  3M8B A;  1XKH A;  2IAH A;  1QFG A;  2W6U A;  4EPA A;  2W76 A;  1FCP A;  1FI1 A;  1NQF A;  1QFF A;  2YSU A;  3CSN A;  4AIP A;  1QKC A;  1PO0 A;  1NQG A;  1UJW A;  3CSL A;  2W16 A;  4B7O A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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