3AUCA

A simplified bpti variant with poly ser (c5s) amino acid tag at the c-terminus
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
58
structure length
58
Chain Sequence
RPAFCLEPPYAGPGKARIIRYFYNAAAGAAQTFVYGGVRAKRNNFASAADALAACAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Effect of amino acid mutations on protein's solubility, function and structure characterized using short poly amino acid peptide tags
rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords Bovine pancreatic trypsin inhibitor
total genus 8
structure length 58
sequence length 58
chains with identical sequence B
ec nomenclature
pdb deposition date 2011-02-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3aucA00
1TAWB 1KNTA 1TOCR 3M7QB 2CA7A 3AUEA 1G6XA 2LFLA 3BTWI 1TFXC 1DENA 1LD5A 2FI4I 1ADZA 3UOUB 2W8XA 1P2QB 1T8MB 1TAPA 2DDJA 5C67C 2ZJXA 2J6DA 2PTCI 4ISLB 1BZXI 1FY8I 1OA55 1P2JI 1OA65 1CA0D 1CO7I 1MTND 2LFKA 3BTDI 3BTTI 3AUDA 4U30W 4Y11I 2TPII 1KTHA 4Y0ZI 1T7CB 2FTMB 1P2NB 2FTLI 3UIRC 3BTGI 4PTIA 2JOTA 1B0CA 4ISOB 1TPAI 1K6UA 1BTIA 1BIKA 8PTIA 2ZVXA 3AUCA 2UUYB 1BTHP 1KUNA 1BPIA 5JB7A 1T8LB 4DTGK 3TGKI 3P92E 4BD9B 1YKTB 3TGJI 3FP7J 2KCRA 3BTQI 3TGII 2ODYE 4Y10I 2KAII 2R9PE 5JB4A 3BTHI 4ISNB 1P2II 3AUGA 9PTIA 1IRHA 1F5RI 3TPII 1DTKA 4TPII 2KNTA 3D65I 4WWYC 3OTJI 4DG4C 2UUXA 1SHPA 4NTYB 1LD6A 1AAPA 5JB5A 1JC6A 1P2KI 1JV9A 3AUBA 5PTIA 1D0DA 1F7ZI 2FI5I 3LDIA 1DEMA 4U32X 1UUBA 2M99A 1KIGI 1QLQA 2M01A 6PTIA 3BTEI 2FI3I 1FAKI 7PTIA 1T8NB 1YLCB 1EJMB 2TGPI 2HEXA 1YLDB 3CI7A 4Y0YI 3AUHA 1NAGA 3L3TE 1BPTA 1BUNB 3U1JE 2DDIA 1EAWB 1ZJDB 1BRCI 1JV8A 4BQDA 3WNYA 4BNRI 3FP8I 1ZR0B 1BF0A 1AALA 1Y62A 3LDJA 1P2OB 1YC0I 4WXVC 5JB6A 1UUAA 3P95E 1TCPA 3FP6I 3OFWA 4NTXB 1T8OB 3BTMI 1CBWD 3AUIA 3BYBA 3L33E 1BRBI 1P2MB 4NTWB 1FANA 1PITA 2IJOI 3BTFI 1DTXA 3LDMA 3T62D 1D0DB 1BHCA 1BZ5A 3GYMI 2RA3C 3BTKI
chains in the Genus database with same CATH superfamily
1TAWB 1KNTA 1TOCR 3M7QB 2CA7A 3AUEA 1G6XA 2LFLA 3BTWI 1TFXC 1DENA 1LD5A 2FI4I 1ADZA 3UOUB 2W8XA 1P2QB 1T8MB 1TAPA 2DDJA 5C67C 2ZJXA 2J6DA 2PTCI 4ISLB 1BZXI 1FY8I 1OA55 1P2JI 1OA65 1CA0D 1CO7I 1MTND 2LFKA 3BTDI 3BTTI 3AUDA 4U30W 4Y11I 2TPII 1KTHA 4Y0ZI 1T7CB 2FTMB 1P2NB 2FTLI 3UIRC 3BTGI 4PTIA 2JOTA 1B0CA 4ISOB 1TPAI 1K6UA 1BTIA 1BIKA 8PTIA 2ZVXA 3AUCA 2UUYB 1BTHP 1KUNA 1BPIA 5JB7A 1T8LB 4DTGK 3TGKI 3P92E 4BD9B 1YKTB 3TGJI 3FP7J 2KCRA 3BTQI 3TGII 2ODYE 4Y10I 2KAII 2R9PE 5JB4A 3BTHI 4ISNB 1P2II 3AUGA 9PTIA 1IRHA 1F5RI 3TPII 1DTKA 4TPII 2KNTA 3D65I 4WWYC 3OTJI 4DG4C 2UUXA 1SHPA 4NTYB 1LD6A 1AAPA 5JB5A 1JC6A 1P2KI 1JV9A 3AUBA 5PTIA 1D0DA 1F7ZI 2FI5I 3LDIA 1DEMA 4U32X 1UUBA 2M99A 1KIGI 1QLQA 2M01A 6PTIA 3BTEI 2FI3I 1FAKI 7PTIA 1T8NB 1YLCB 1EJMB 2TGPI 2HEXA 1YLDB 3CI7A 4Y0YI 3AUHA 1NAGA 3L3TE 1BPTA 1BUNB 3U1JE 2DDIA 1EAWB 1ZJDB 1BRCI 1JV8A 4BQDA 3WNYA 4BNRI 3FP8I 1ZR0B 1BF0A 1AALA 1Y62A 3LDJA 1P2OB 1YC0I 4WXVC 5JB6A 1UUAA 3P95E 1TCPA 3FP6I 3OFWA 4NTXB 1T8OB 3BTMI 1CBWD 3AUIA 3BYBA 3L33E 1BRBI 1P2MB 4NTWB 1FANA 1PITA 2IJOI 3BTFI 1DTXA 3LDMA 3T62D 1D0DB 1BHCA 1BZ5A 3GYMI 2RA3C 3BTKI
chains in the Genus database with same CATH topology
1TAWB 1KNTA 1TOCR 3M7QB 2CA7A 3AUEA 1G6XA 2LFLA 3BTWI 1TFXC 1DENA 1LD5A 2FI4I 1ADZA 3UOUB 2W8XA 1P2QB 1T8MB 1TAPA 2DDJA 5C67C 2ZJXA 2J6DA 2PTCI 4ISLB 1BZXI 1FY8I 1OA55 1P2JI 1OA65 1CA0D 1CO7I 1MTND 2LFKA 3BTDI 3BTTI 3AUDA 4U30W 4Y11I 2TPII 1KTHA 4Y0ZI 1T7CB 2FTMB 1P2NB 2FTLI 3UIRC 3BTGI 4PTIA 2JOTA 1B0CA 4ISOB 1TPAI 1K6UA 1BTIA 1BIKA 8PTIA 2ZVXA 3AUCA 2UUYB 1BTHP 1KUNA 1BPIA 5JB7A 1T8LB 4DTGK 3TGKI 3P92E 4BD9B 1YKTB 3TGJI 3FP7J 2KCRA 3BTQI 3TGII 2ODYE 4Y10I 2KAII 2R9PE 5JB4A 3BTHI 4ISNB 1P2II 3AUGA 9PTIA 1IRHA 1F5RI 3TPII 1DTKA 4TPII 2KNTA 3D65I 4WWYC 3OTJI 4DG4C 2UUXA 1SHPA 4NTYB 1LD6A 1AAPA 5JB5A 1JC6A 1P2KI 1JV9A 3AUBA 5PTIA 1D0DA 1F7ZI 2FI5I 3LDIA 1DEMA 4U32X 1UUBA 2M99A 1KIGI 1QLQA 2M01A 6PTIA 3BTEI 2FI3I 1FAKI 7PTIA 1T8NB 1YLCB 1EJMB 2TGPI 2HEXA 1YLDB 3CI7A 4Y0YI 3AUHA 1NAGA 3L3TE 1BPTA 1BUNB 3U1JE 2DDIA 1EAWB 1ZJDB 1BRCI 1JV8A 4BQDA 3WNYA 4BNRI 3FP8I 1ZR0B 1BF0A 1AALA 1Y62A 3LDJA 1P2OB 1YC0I 4WXVC 5JB6A 1UUAA 3P95E 1TCPA 3FP6I 3OFWA 4NTXB 1T8OB 3BTMI 1CBWD 3AUIA 3BYBA 3L33E 1BRBI 1P2MB 4NTWB 1FANA 1PITA 2IJOI 3BTFI 1DTXA 3LDMA 3T62D 1D0DB 1BHCA 1BZ5A 3GYMI 2RA3C 3BTKI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TAW B;  1KNT A;  1TOC R;  3M7Q B;  2CA7 A;  3AUE A;  1G6X A;  2LFL A;  3BTW I;  1TFX C;  1DEN A;  1LD5 A;  2FI4 I;  1ADZ A;  3UOU B;  2W8X A;  1P2Q B;  1T8M B;  1TAP A;  2DDJ A;  5C67 C;  2ZJX A;  2J6D A;  2PTC I;  4ISL B;  1BZX I;  1FY8 I;  1OA5 5;  1P2J I;  1OA6 5;  1CA0 D;  1CO7 I;  1MTN D;  2LFK A;  3BTD I;  3BTT I;  3AUD A;  4U30 W;  4Y11 I;  2TPI I;  1KTH A;  4Y0Z I;  1T7C B;  2FTM B;  1P2N B;  2FTL I;  3UIR C;  3BTG I;  4PTI A;  2JOT A;  1B0C A;  4ISO B;  1TPA I;  1K6U A;  1BTI A;  1BIK A;  8PTI A;  2ZVX A;  3AUC A;  2UUY B;  1BTH P;  1KUN A;  1BPI A;  5JB7 A;  1T8L B;  4DTG K;  3TGK I;  3P92 E;  4BD9 B;  1YKT B;  3TGJ I;  3FP7 J;  2KCR A;  3BTQ I;  3TGI I;  2ODY E;  4Y10 I;  2KAI I;  2R9P E;  5JB4 A;  3BTH I;  4ISN B;  1P2I I;  3AUG A;  9PTI A;  1IRH A;  1F5R I;  3TPI I;  1DTK A;  4TPI I;  2KNT A;  3D65 I;  4WWY C;  3OTJ I;  4DG4 C;  2UUX A;  1SHP A;  4NTY B;  1LD6 A;  1AAP A;  5JB5 A;  1JC6 A;  1P2K I;  1JV9 A;  3AUB A;  5PTI A;  1D0D A;  1F7Z I;  2FI5 I;  3LDI A;  1DEM A;  4U32 X;  1UUB A;  2M99 A;  1KIG I;  1QLQ A;  2M01 A;  6PTI A;  3BTE I;  2FI3 I;  1FAK I;  7PTI A;  1T8N B;  1YLC B;  1EJM B;  2TGP I;  2HEX A;  1YLD B;  3CI7 A;  4Y0Y I;  3AUH A;  1NAG A;  3L3T E;  1BPT A;  1BUN B;  3U1J E;  2DDI A;  1EAW B;  1ZJD B;  1BRC I;  1JV8 A;  4BQD A;  3WNY A;  4BNR I;  3FP8 I;  1ZR0 B;  1BF0 A;  1AAL A;  1Y62 A;  3LDJ A;  1P2O B;  1YC0 I;  4WXV C;  5JB6 A;  1UUA A;  3P95 E;  1TCP A;  3FP6 I;  3OFW A;  4NTX B;  1T8O B;  3BTM I;  1CBW D;  3AUI A;  3BYB A;  3L33 E;  1BRB I;  1P2M B;  4NTW B;  1FAN A;  1PIT A;  2IJO I;  3BTF I;  1DTX A;  3LDM A;  3T62 D;  1D0D B;  1BHC A;  1BZ5 A;  3GYM I;  2RA3 C;  3BTK I; 
#chains in the Genus database with same CATH topology
 1TAW B;  1KNT A;  1TOC R;  3M7Q B;  2CA7 A;  3AUE A;  1G6X A;  2LFL A;  3BTW I;  1TFX C;  1DEN A;  1LD5 A;  2FI4 I;  1ADZ A;  3UOU B;  2W8X A;  1P2Q B;  1T8M B;  1TAP A;  2DDJ A;  5C67 C;  2ZJX A;  2J6D A;  2PTC I;  4ISL B;  1BZX I;  1FY8 I;  1OA5 5;  1P2J I;  1OA6 5;  1CA0 D;  1CO7 I;  1MTN D;  2LFK A;  3BTD I;  3BTT I;  3AUD A;  4U30 W;  4Y11 I;  2TPI I;  1KTH A;  4Y0Z I;  1T7C B;  2FTM B;  1P2N B;  2FTL I;  3UIR C;  3BTG I;  4PTI A;  2JOT A;  1B0C A;  4ISO B;  1TPA I;  1K6U A;  1BTI A;  1BIK A;  8PTI A;  2ZVX A;  3AUC A;  2UUY B;  1BTH P;  1KUN A;  1BPI A;  5JB7 A;  1T8L B;  4DTG K;  3TGK I;  3P92 E;  4BD9 B;  1YKT B;  3TGJ I;  3FP7 J;  2KCR A;  3BTQ I;  3TGI I;  2ODY E;  4Y10 I;  2KAI I;  2R9P E;  5JB4 A;  3BTH I;  4ISN B;  1P2I I;  3AUG A;  9PTI A;  1IRH A;  1F5R I;  3TPI I;  1DTK A;  4TPI I;  2KNT A;  3D65 I;  4WWY C;  3OTJ I;  4DG4 C;  2UUX A;  1SHP A;  4NTY B;  1LD6 A;  1AAP A;  5JB5 A;  1JC6 A;  1P2K I;  1JV9 A;  3AUB A;  5PTI A;  1D0D A;  1F7Z I;  2FI5 I;  3LDI A;  1DEM A;  4U32 X;  1UUB A;  2M99 A;  1KIG I;  1QLQ A;  2M01 A;  6PTI A;  3BTE I;  2FI3 I;  1FAK I;  7PTI A;  1T8N B;  1YLC B;  1EJM B;  2TGP I;  2HEX A;  1YLD B;  3CI7 A;  4Y0Y I;  3AUH A;  1NAG A;  3L3T E;  1BPT A;  1BUN B;  3U1J E;  2DDI A;  1EAW B;  1ZJD B;  1BRC I;  1JV8 A;  4BQD A;  3WNY A;  4BNR I;  3FP8 I;  1ZR0 B;  1BF0 A;  1AAL A;  1Y62 A;  3LDJ A;  1P2O B;  1YC0 I;  4WXV C;  5JB6 A;  1UUA A;  3P95 E;  1TCP A;  3FP6 I;  3OFW A;  4NTX B;  1T8O B;  3BTM I;  1CBW D;  3AUI A;  3BYB A;  3L33 E;  1BRB I;  1P2M B;  4NTW B;  1FAN A;  1PIT A;  2IJO I;  3BTF I;  1DTX A;  3LDM A;  3T62 D;  1D0D B;  1BHC A;  1BZ5 A;  3GYM I;  2RA3 C;  3BTK I; 
#chains in the Genus database with same CATH homology
 1TAW B;  1KNT A;  1TOC R;  3M7Q B;  2CA7 A;  3AUE A;  1G6X A;  2LFL A;  3BTW I;  1TFX C;  1DEN A;  1LD5 A;  2FI4 I;  1ADZ A;  3UOU B;  2W8X A;  1P2Q B;  1T8M B;  1TAP A;  2DDJ A;  5C67 C;  2ZJX A;  2J6D A;  2PTC I;  4ISL B;  1BZX I;  1FY8 I;  1OA5 5;  1P2J I;  1OA6 5;  1CA0 D;  1CO7 I;  1MTN D;  2LFK A;  3BTD I;  3BTT I;  3AUD A;  4U30 W;  4Y11 I;  2TPI I;  1KTH A;  4Y0Z I;  1T7C B;  2FTM B;  1P2N B;  2FTL I;  3UIR C;  3BTG I;  4PTI A;  2JOT A;  1B0C A;  4ISO B;  1TPA I;  1K6U A;  1BTI A;  1BIK A;  8PTI A;  2ZVX A;  3AUC A;  2UUY B;  1BTH P;  1KUN A;  1BPI A;  5JB7 A;  1T8L B;  4DTG K;  3TGK I;  3P92 E;  4BD9 B;  1YKT B;  3TGJ I;  3FP7 J;  2KCR A;  3BTQ I;  3TGI I;  2ODY E;  4Y10 I;  2KAI I;  2R9P E;  5JB4 A;  3BTH I;  4ISN B;  1P2I I;  3AUG A;  9PTI A;  1IRH A;  1F5R I;  3TPI I;  1DTK A;  4TPI I;  2KNT A;  3D65 I;  4WWY C;  3OTJ I;  4DG4 C;  2UUX A;  1SHP A;  4NTY B;  1LD6 A;  1AAP A;  5JB5 A;  1JC6 A;  1P2K I;  1JV9 A;  3AUB A;  5PTI A;  1D0D A;  1F7Z I;  2FI5 I;  3LDI A;  1DEM A;  4U32 X;  1UUB A;  2M99 A;  1KIG I;  1QLQ A;  2M01 A;  6PTI A;  3BTE I;  2FI3 I;  1FAK I;  7PTI A;  1T8N B;  1YLC B;  1EJM B;  2TGP I;  2HEX A;  1YLD B;  3CI7 A;  4Y0Y I;  3AUH A;  1NAG A;  3L3T E;  1BPT A;  1BUN B;  3U1J E;  2DDI A;  1EAW B;  1ZJD B;  1BRC I;  1JV8 A;  4BQD A;  3WNY A;  4BNR I;  3FP8 I;  1ZR0 B;  1BF0 A;  1AAL A;  1Y62 A;  3LDJ A;  1P2O B;  1YC0 I;  4WXV C;  5JB6 A;  1UUA A;  3P95 E;  1TCP A;  3FP6 I;  3OFW A;  4NTX B;  1T8O B;  3BTM I;  1CBW D;  3AUI A;  3BYB A;  3L33 E;  1BRB I;  1P2M B;  4NTW B;  1FAN A;  1PIT A;  2IJO I;  3BTF I;  1DTX A;  3LDM A;  3T62 D;  1D0D B;  1BHC A;  1BZ5 A;  3GYM I;  2RA3 C;  3BTK I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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