3AUEA

A simplified bpti variant with poly his amino acid tag (c5h) at the c-terminus
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
57
structure length
57
Chain Sequence
RPAFCLEPPYAGPGKARIIRYFYNAAAGAAQAFVYGGVRAKRNNFASAADALAACAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Effect of amino acid mutations on protein's solubility, function and structure characterized using short poly amino acid peptide tags
rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords Bovine pancreatic trypsin inhibitor
total genus 8
structure length 57
sequence length 57
chains with identical sequence B, C, D, E, F, G, H
ec nomenclature
pdb deposition date 2011-02-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3aueA00
1DEMA 1JV9A 1JC6A 1KIGI 3UOUB 2M01A 3BTWI 4Y0ZI 3U1JE 1BRCI 4NTYB 1BIKA 3BTGI 2J6DA 3BTMI 1BHCA 1P2OB 1YKTB 3OFWA 5PTIA 2FTMB 4WWYC 2DDJA 1KTHA 1P2II 3TGJI 3AUHA 3BTQI 2KNTA 3LDIA 1TAPA 1T8MB 9PTIA 2UUXA 1DTXA 4DG4C 3BTFI 4U30W 3BTDI 1OA55 1P2JI 4Y0YI 5JB4A 1T8OB 2UUYB 4DTGK 3AUBA 1B0CA 2JOTA 1TCPA 3AUCA 1YLCB 7PTIA 1D0DA 1LD5A 1LD6A 4ISLB 1FAKI 1KNTA 1TFXC 3AUEA 4WXVC 1JV8A 1MTND 2M99A 1G6XA 1P2QB 1IRHA 1T8LB 1BRBI 3CI7A 1AAPA 3BTHI 2CA7A 1AALA 2FI5I 2FTLI 3FP7J 3GYMI 1F7ZI 1F5RI 1TPAI 1UUBA 3AUIA 3TGKI 1BPIA 4PTIA 4BQDA 1DTKA 1FY8I 6PTIA 1BZXI 5JB7A 3P92E 2ZVXA 3UIRC 3BTEI 2R9PE 2LFKA 1YC0I 3LDJA 1EJMB 1K6UA 1CBWD 3FP6I 4TPII 3FP8I 2PTCI 1P2NB 2ZJXA 5JB6A 4NTWB 2IJOI 3AUDA 3TPII 3BYBA 3AUGA 1D0DB 3P95E 3L33E 2DDIA 2KAII 2FI4I 3BTKI 1BF0A 1ZR0B 1OA65 1BUNB 8PTIA 1CO7I 1YLDB 2FI3I 1TAWB 4ISNB 1NAGA 1Y62A 2HEXA 1TOCR 1CA0D 4Y10I 2LFLA 1P2KI 1UUAA 1DENA 4NTXB 2TPII 2W8XA 3T62D 1QLQA 3TGII 1T7CB 1BTHP 3OTJI 4BNRI 5C67C 3D65I 1PITA 3WNYA 1P2MB 3LDMA 1EAWB 1T8NB 5JB5A 4BD9B 1ADZA 1SHPA 4Y11I 1BPTA 1FANA 3L3TE 2ODYE 2TGPI 4ISOB 1BTIA 3M7QB 2KCRA 1KUNA 2RA3C 4U32X 1ZJDB 1BZ5A 3BTTI
chains in the Genus database with same CATH superfamily
1DEMA 1JV9A 1JC6A 1KIGI 3UOUB 2M01A 3BTWI 4Y0ZI 3U1JE 1BRCI 4NTYB 1BIKA 3BTGI 2J6DA 3BTMI 1BHCA 1P2OB 1YKTB 3OFWA 5PTIA 2FTMB 4WWYC 2DDJA 1KTHA 1P2II 3TGJI 3AUHA 3BTQI 2KNTA 3LDIA 1TAPA 1T8MB 9PTIA 2UUXA 1DTXA 4DG4C 3BTFI 4U30W 3BTDI 1OA55 1P2JI 4Y0YI 5JB4A 1T8OB 2UUYB 4DTGK 3AUBA 1B0CA 2JOTA 1TCPA 3AUCA 1YLCB 7PTIA 1D0DA 1LD5A 1LD6A 4ISLB 1FAKI 1KNTA 1TFXC 3AUEA 4WXVC 1JV8A 1MTND 2M99A 1G6XA 1P2QB 1IRHA 1T8LB 1BRBI 3CI7A 1AAPA 3BTHI 2CA7A 1AALA 2FI5I 2FTLI 3FP7J 3GYMI 1F7ZI 1F5RI 1TPAI 1UUBA 3AUIA 3TGKI 1BPIA 4PTIA 4BQDA 1DTKA 1FY8I 6PTIA 1BZXI 5JB7A 3P92E 2ZVXA 3UIRC 3BTEI 2R9PE 2LFKA 1YC0I 3LDJA 1EJMB 1K6UA 1CBWD 3FP6I 4TPII 3FP8I 2PTCI 1P2NB 2ZJXA 5JB6A 4NTWB 2IJOI 3AUDA 3TPII 3BYBA 3AUGA 1D0DB 3P95E 3L33E 2DDIA 2KAII 2FI4I 3BTKI 1BF0A 1ZR0B 1OA65 1BUNB 8PTIA 1CO7I 1YLDB 2FI3I 1TAWB 4ISNB 1NAGA 1Y62A 2HEXA 1TOCR 1CA0D 4Y10I 2LFLA 1P2KI 1UUAA 1DENA 4NTXB 2TPII 2W8XA 3T62D 1QLQA 3TGII 1T7CB 1BTHP 3OTJI 4BNRI 5C67C 3D65I 1PITA 3WNYA 1P2MB 3LDMA 1EAWB 1T8NB 5JB5A 4BD9B 1ADZA 1SHPA 4Y11I 1BPTA 1FANA 3L3TE 2ODYE 2TGPI 4ISOB 1BTIA 3M7QB 2KCRA 1KUNA 2RA3C 4U32X 1ZJDB 1BZ5A 3BTTI
chains in the Genus database with same CATH topology
1DEMA 1JV9A 1JC6A 1KIGI 3UOUB 2M01A 3BTWI 4Y0ZI 3U1JE 1BRCI 4NTYB 1BIKA 3BTGI 2J6DA 3BTMI 1BHCA 1P2OB 1YKTB 3OFWA 5PTIA 2FTMB 4WWYC 2DDJA 1KTHA 1P2II 3TGJI 3AUHA 3BTQI 2KNTA 3LDIA 1TAPA 1T8MB 9PTIA 2UUXA 1DTXA 4DG4C 3BTFI 4U30W 3BTDI 1OA55 1P2JI 4Y0YI 5JB4A 1T8OB 2UUYB 4DTGK 3AUBA 1B0CA 2JOTA 1TCPA 3AUCA 1YLCB 7PTIA 1D0DA 1LD5A 1LD6A 4ISLB 1FAKI 1KNTA 1TFXC 3AUEA 4WXVC 1JV8A 1MTND 2M99A 1G6XA 1P2QB 1IRHA 1T8LB 1BRBI 3CI7A 1AAPA 3BTHI 2CA7A 1AALA 2FI5I 2FTLI 3FP7J 3GYMI 1F7ZI 1F5RI 1TPAI 1UUBA 3AUIA 3TGKI 1BPIA 4PTIA 4BQDA 1DTKA 1FY8I 6PTIA 1BZXI 5JB7A 3P92E 2ZVXA 3UIRC 3BTEI 2R9PE 2LFKA 1YC0I 3LDJA 1EJMB 1K6UA 1CBWD 3FP6I 4TPII 3FP8I 2PTCI 1P2NB 2ZJXA 5JB6A 4NTWB 2IJOI 3AUDA 3TPII 3BYBA 3AUGA 1D0DB 3P95E 3L33E 2DDIA 2KAII 2FI4I 3BTKI 1BF0A 1ZR0B 1OA65 1BUNB 8PTIA 1CO7I 1YLDB 2FI3I 1TAWB 4ISNB 1NAGA 1Y62A 2HEXA 1TOCR 1CA0D 4Y10I 2LFLA 1P2KI 1UUAA 1DENA 4NTXB 2TPII 2W8XA 3T62D 1QLQA 3TGII 1T7CB 1BTHP 3OTJI 4BNRI 5C67C 3D65I 1PITA 3WNYA 1P2MB 3LDMA 1EAWB 1T8NB 5JB5A 4BD9B 1ADZA 1SHPA 4Y11I 1BPTA 1FANA 3L3TE 2ODYE 2TGPI 4ISOB 1BTIA 3M7QB 2KCRA 1KUNA 2RA3C 4U32X 1ZJDB 1BZ5A 3BTTI
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1DEM A;  1JV9 A;  1JC6 A;  1KIG I;  3UOU B;  2M01 A;  3BTW I;  4Y0Z I;  3U1J E;  1BRC I;  4NTY B;  1BIK A;  3BTG I;  2J6D A;  3BTM I;  1BHC A;  1P2O B;  1YKT B;  3OFW A;  5PTI A;  2FTM B;  4WWY C;  2DDJ A;  1KTH A;  1P2I I;  3TGJ I;  3AUH A;  3BTQ I;  2KNT A;  3LDI A;  1TAP A;  1T8M B;  9PTI A;  2UUX A;  1DTX A;  4DG4 C;  3BTF I;  4U30 W;  3BTD I;  1OA5 5;  1P2J I;  4Y0Y I;  5JB4 A;  1T8O B;  2UUY B;  4DTG K;  3AUB A;  1B0C A;  2JOT A;  1TCP A;  3AUC A;  1YLC B;  7PTI A;  1D0D A;  1LD5 A;  1LD6 A;  4ISL B;  1FAK I;  1KNT A;  1TFX C;  3AUE A;  4WXV C;  1JV8 A;  1MTN D;  2M99 A;  1G6X A;  1P2Q B;  1IRH A;  1T8L B;  1BRB I;  3CI7 A;  1AAP A;  3BTH I;  2CA7 A;  1AAL A;  2FI5 I;  2FTL I;  3FP7 J;  3GYM I;  1F7Z I;  1F5R I;  1TPA I;  1UUB A;  3AUI A;  3TGK I;  1BPI A;  4PTI A;  4BQD A;  1DTK A;  1FY8 I;  6PTI A;  1BZX I;  5JB7 A;  3P92 E;  2ZVX A;  3UIR C;  3BTE I;  2R9P E;  2LFK A;  1YC0 I;  3LDJ A;  1EJM B;  1K6U A;  1CBW D;  3FP6 I;  4TPI I;  3FP8 I;  2PTC I;  1P2N B;  2ZJX A;  5JB6 A;  4NTW B;  2IJO I;  3AUD A;  3TPI I;  3BYB A;  3AUG A;  1D0D B;  3P95 E;  3L33 E;  2DDI A;  2KAI I;  2FI4 I;  3BTK I;  1BF0 A;  1ZR0 B;  1OA6 5;  1BUN B;  8PTI A;  1CO7 I;  1YLD B;  2FI3 I;  1TAW B;  4ISN B;  1NAG A;  1Y62 A;  2HEX A;  1TOC R;  1CA0 D;  4Y10 I;  2LFL A;  1P2K I;  1UUA A;  1DEN A;  4NTX B;  2TPI I;  2W8X A;  3T62 D;  1QLQ A;  3TGI I;  1T7C B;  1BTH P;  3OTJ I;  4BNR I;  5C67 C;  3D65 I;  1PIT A;  3WNY A;  1P2M B;  3LDM A;  1EAW B;  1T8N B;  5JB5 A;  4BD9 B;  1ADZ A;  1SHP A;  4Y11 I;  1BPT A;  1FAN A;  3L3T E;  2ODY E;  2TGP I;  4ISO B;  1BTI A;  3M7Q B;  2KCR A;  1KUN A;  2RA3 C;  4U32 X;  1ZJD B;  1BZ5 A;  3BTT I; 
#chains in the Genus database with same CATH topology
 1DEM A;  1JV9 A;  1JC6 A;  1KIG I;  3UOU B;  2M01 A;  3BTW I;  4Y0Z I;  3U1J E;  1BRC I;  4NTY B;  1BIK A;  3BTG I;  2J6D A;  3BTM I;  1BHC A;  1P2O B;  1YKT B;  3OFW A;  5PTI A;  2FTM B;  4WWY C;  2DDJ A;  1KTH A;  1P2I I;  3TGJ I;  3AUH A;  3BTQ I;  2KNT A;  3LDI A;  1TAP A;  1T8M B;  9PTI A;  2UUX A;  1DTX A;  4DG4 C;  3BTF I;  4U30 W;  3BTD I;  1OA5 5;  1P2J I;  4Y0Y I;  5JB4 A;  1T8O B;  2UUY B;  4DTG K;  3AUB A;  1B0C A;  2JOT A;  1TCP A;  3AUC A;  1YLC B;  7PTI A;  1D0D A;  1LD5 A;  1LD6 A;  4ISL B;  1FAK I;  1KNT A;  1TFX C;  3AUE A;  4WXV C;  1JV8 A;  1MTN D;  2M99 A;  1G6X A;  1P2Q B;  1IRH A;  1T8L B;  1BRB I;  3CI7 A;  1AAP A;  3BTH I;  2CA7 A;  1AAL A;  2FI5 I;  2FTL I;  3FP7 J;  3GYM I;  1F7Z I;  1F5R I;  1TPA I;  1UUB A;  3AUI A;  3TGK I;  1BPI A;  4PTI A;  4BQD A;  1DTK A;  1FY8 I;  6PTI A;  1BZX I;  5JB7 A;  3P92 E;  2ZVX A;  3UIR C;  3BTE I;  2R9P E;  2LFK A;  1YC0 I;  3LDJ A;  1EJM B;  1K6U A;  1CBW D;  3FP6 I;  4TPI I;  3FP8 I;  2PTC I;  1P2N B;  2ZJX A;  5JB6 A;  4NTW B;  2IJO I;  3AUD A;  3TPI I;  3BYB A;  3AUG A;  1D0D B;  3P95 E;  3L33 E;  2DDI A;  2KAI I;  2FI4 I;  3BTK I;  1BF0 A;  1ZR0 B;  1OA6 5;  1BUN B;  8PTI A;  1CO7 I;  1YLD B;  2FI3 I;  1TAW B;  4ISN B;  1NAG A;  1Y62 A;  2HEX A;  1TOC R;  1CA0 D;  4Y10 I;  2LFL A;  1P2K I;  1UUA A;  1DEN A;  4NTX B;  2TPI I;  2W8X A;  3T62 D;  1QLQ A;  3TGI I;  1T7C B;  1BTH P;  3OTJ I;  4BNR I;  5C67 C;  3D65 I;  1PIT A;  3WNY A;  1P2M B;  3LDM A;  1EAW B;  1T8N B;  5JB5 A;  4BD9 B;  1ADZ A;  1SHP A;  4Y11 I;  1BPT A;  1FAN A;  3L3T E;  2ODY E;  2TGP I;  4ISO B;  1BTI A;  3M7Q B;  2KCR A;  1KUN A;  2RA3 C;  4U32 X;  1ZJD B;  1BZ5 A;  3BTT I; 
#chains in the Genus database with same CATH homology
 1DEM A;  1JV9 A;  1JC6 A;  1KIG I;  3UOU B;  2M01 A;  3BTW I;  4Y0Z I;  3U1J E;  1BRC I;  4NTY B;  1BIK A;  3BTG I;  2J6D A;  3BTM I;  1BHC A;  1P2O B;  1YKT B;  3OFW A;  5PTI A;  2FTM B;  4WWY C;  2DDJ A;  1KTH A;  1P2I I;  3TGJ I;  3AUH A;  3BTQ I;  2KNT A;  3LDI A;  1TAP A;  1T8M B;  9PTI A;  2UUX A;  1DTX A;  4DG4 C;  3BTF I;  4U30 W;  3BTD I;  1OA5 5;  1P2J I;  4Y0Y I;  5JB4 A;  1T8O B;  2UUY B;  4DTG K;  3AUB A;  1B0C A;  2JOT A;  1TCP A;  3AUC A;  1YLC B;  7PTI A;  1D0D A;  1LD5 A;  1LD6 A;  4ISL B;  1FAK I;  1KNT A;  1TFX C;  3AUE A;  4WXV C;  1JV8 A;  1MTN D;  2M99 A;  1G6X A;  1P2Q B;  1IRH A;  1T8L B;  1BRB I;  3CI7 A;  1AAP A;  3BTH I;  2CA7 A;  1AAL A;  2FI5 I;  2FTL I;  3FP7 J;  3GYM I;  1F7Z I;  1F5R I;  1TPA I;  1UUB A;  3AUI A;  3TGK I;  1BPI A;  4PTI A;  4BQD A;  1DTK A;  1FY8 I;  6PTI A;  1BZX I;  5JB7 A;  3P92 E;  2ZVX A;  3UIR C;  3BTE I;  2R9P E;  2LFK A;  1YC0 I;  3LDJ A;  1EJM B;  1K6U A;  1CBW D;  3FP6 I;  4TPI I;  3FP8 I;  2PTC I;  1P2N B;  2ZJX A;  5JB6 A;  4NTW B;  2IJO I;  3AUD A;  3TPI I;  3BYB A;  3AUG A;  1D0D B;  3P95 E;  3L33 E;  2DDI A;  2KAI I;  2FI4 I;  3BTK I;  1BF0 A;  1ZR0 B;  1OA6 5;  1BUN B;  8PTI A;  1CO7 I;  1YLD B;  2FI3 I;  1TAW B;  4ISN B;  1NAG A;  1Y62 A;  2HEX A;  1TOC R;  1CA0 D;  4Y10 I;  2LFL A;  1P2K I;  1UUA A;  1DEN A;  4NTX B;  2TPI I;  2W8X A;  3T62 D;  1QLQ A;  3TGI I;  1T7C B;  1BTH P;  3OTJ I;  4BNR I;  5C67 C;  3D65 I;  1PIT A;  3WNY A;  1P2M B;  3LDM A;  1EAW B;  1T8N B;  5JB5 A;  4BD9 B;  1ADZ A;  1SHP A;  4Y11 I;  1BPT A;  1FAN A;  3L3T E;  2ODY E;  2TGP I;  4ISO B;  1BTI A;  3M7Q B;  2KCR A;  1KUN A;  2RA3 C;  4U32 X;  1ZJD B;  1BZ5 A;  3BTT I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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