3AUHA

A simplified bpti variant with poly arg amino acid tag (c3r) at the c-terminus
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
56
structure length
56
Chain Sequence
RPAFCLEPPYAGPGKARIIRYFYNAAAGAAQAFVYGGVRAKRNNFASAADALAACA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Effect of amino acid mutations on protein's solubility, function and structure characterized using short poly amino acid peptide tags
rcsb
molecule tags Hydrolase inhibitor
source organism Bos taurus
molecule keywords Bovine pancreatic trypsin inhibitor
total genus 8
structure length 56
sequence length 56
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2011-02-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3auhA00
1OA55 3OFWA 2TGPI 1P2II 1CO7I 4U32X 2KNTA 3BTFI 1CBWD 1JC6A 4TPII 4ISLB 3L33E 3BTHI 3OTJI 4Y10I 3AUIA 3BTGI 1JV9A 1ZR0B 1EJMB 1P2JI 1TPAI 3TGKI 1T8NB 2KCRA 2PTCI 4PTIA 1D0DA 2FTLI 1BTHP 3FP8I 1ADZA 1DTXA 3BTTI 1TCPA 1UUBA 4DTGK 3GYMI 3BTEI 1YLDB 2KAII 1BHCA 2IJOI 1BTIA 1P2QB 3UOUB 3TGII 7PTIA 1TAPA 3FP7J 4WWYC 3T62D 4NTYB 1JV8A 3UIRC 3BTMI 3LDJA 3FP6I 2ZVXA 3BTWI 5JB5A 2LFKA 4Y11I 1T8OB 2LFLA 1DENA 3WNYA 2TPII 1F7ZI 3BTDI 2HEXA 1PITA 3BTQI 1KIGI 1AAPA 1K6UA 4BNRI 4ISOB 4ISNB 2JOTA 1BPIA 1BRBI 1FANA 3AUDA 1P2KI 1TAWB 2J6DA 3L3TE 2ZJXA 3LDMA 1MTND 3AUGA 1SHPA 1T7CB 1Y62A 2M99A 4Y0ZI 5C67C 2UUXA 1EAWB 2FI5I 4NTWB 1P2OB 5JB6A 2DDIA 1BF0A 3AUHA 8PTIA 1YKTB 3AUCA 1DTKA 2M01A 2ODYE 1CA0D 2FTMB 1FAKI 1LD6A 4Y0YI 4BQDA 1IRHA 1TOCR 5JB7A 3M7QB 1BUNB 1D0DB 3AUEA 2FI4I 1ZJDB 1BZ5A 4U30W 1BRCI 5PTIA 3TPII 2W8XA 3AUBA 1YC0I 2CA7A 3BYBA 1P2NB 1LD5A 4NTXB 1AALA 1UUAA 3D65I 2DDJA 1F5RI 6PTIA 4WXVC 3BTKI 9PTIA 1BZXI 1QLQA 1DEMA 1FY8I 3U1JE 3P92E 1T8MB 1P2MB 1KUNA 1NAGA 1G6XA 1KTHA 1OA65 1BPTA 2FI3I 4BD9B 1YLCB 3LDIA 1TFXC 1KNTA 1T8LB 3TGJI 2UUYB 2R9PE 5JB4A 3CI7A 1B0CA 2RA3C 3P95E 4DG4C 1BIKA
chains in the Genus database with same CATH superfamily
1OA55 3OFWA 2TGPI 1P2II 1CO7I 4U32X 2KNTA 3BTFI 1CBWD 1JC6A 4TPII 4ISLB 3L33E 3BTHI 3OTJI 4Y10I 3AUIA 3BTGI 1JV9A 1ZR0B 1EJMB 1P2JI 1TPAI 3TGKI 1T8NB 2KCRA 2PTCI 4PTIA 1D0DA 2FTLI 1BTHP 3FP8I 1ADZA 1DTXA 3BTTI 1TCPA 1UUBA 4DTGK 3GYMI 3BTEI 1YLDB 2KAII 1BHCA 2IJOI 1BTIA 1P2QB 3UOUB 3TGII 7PTIA 1TAPA 3FP7J 4WWYC 3T62D 4NTYB 1JV8A 3UIRC 3BTMI 3LDJA 3FP6I 2ZVXA 3BTWI 5JB5A 2LFKA 4Y11I 1T8OB 2LFLA 1DENA 3WNYA 2TPII 1F7ZI 3BTDI 2HEXA 1PITA 3BTQI 1KIGI 1AAPA 1K6UA 4BNRI 4ISOB 4ISNB 2JOTA 1BPIA 1BRBI 1FANA 3AUDA 1P2KI 1TAWB 2J6DA 3L3TE 2ZJXA 3LDMA 1MTND 3AUGA 1SHPA 1T7CB 1Y62A 2M99A 4Y0ZI 5C67C 2UUXA 1EAWB 2FI5I 4NTWB 1P2OB 5JB6A 2DDIA 1BF0A 3AUHA 8PTIA 1YKTB 3AUCA 1DTKA 2M01A 2ODYE 1CA0D 2FTMB 1FAKI 1LD6A 4Y0YI 4BQDA 1IRHA 1TOCR 5JB7A 3M7QB 1BUNB 1D0DB 3AUEA 2FI4I 1ZJDB 1BZ5A 4U30W 1BRCI 5PTIA 3TPII 2W8XA 3AUBA 1YC0I 2CA7A 3BYBA 1P2NB 1LD5A 4NTXB 1AALA 1UUAA 3D65I 2DDJA 1F5RI 6PTIA 4WXVC 3BTKI 9PTIA 1BZXI 1QLQA 1DEMA 1FY8I 3U1JE 3P92E 1T8MB 1P2MB 1KUNA 1NAGA 1G6XA 1KTHA 1OA65 1BPTA 2FI3I 4BD9B 1YLCB 3LDIA 1TFXC 1KNTA 1T8LB 3TGJI 2UUYB 2R9PE 5JB4A 3CI7A 1B0CA 2RA3C 3P95E 4DG4C 1BIKA
chains in the Genus database with same CATH topology
1OA55 3OFWA 2TGPI 1P2II 1CO7I 4U32X 2KNTA 3BTFI 1CBWD 1JC6A 4TPII 4ISLB 3L33E 3BTHI 3OTJI 4Y10I 3AUIA 3BTGI 1JV9A 1ZR0B 1EJMB 1P2JI 1TPAI 3TGKI 1T8NB 2KCRA 2PTCI 4PTIA 1D0DA 2FTLI 1BTHP 3FP8I 1ADZA 1DTXA 3BTTI 1TCPA 1UUBA 4DTGK 3GYMI 3BTEI 1YLDB 2KAII 1BHCA 2IJOI 1BTIA 1P2QB 3UOUB 3TGII 7PTIA 1TAPA 3FP7J 4WWYC 3T62D 4NTYB 1JV8A 3UIRC 3BTMI 3LDJA 3FP6I 2ZVXA 3BTWI 5JB5A 2LFKA 4Y11I 1T8OB 2LFLA 1DENA 3WNYA 2TPII 1F7ZI 3BTDI 2HEXA 1PITA 3BTQI 1KIGI 1AAPA 1K6UA 4BNRI 4ISOB 4ISNB 2JOTA 1BPIA 1BRBI 1FANA 3AUDA 1P2KI 1TAWB 2J6DA 3L3TE 2ZJXA 3LDMA 1MTND 3AUGA 1SHPA 1T7CB 1Y62A 2M99A 4Y0ZI 5C67C 2UUXA 1EAWB 2FI5I 4NTWB 1P2OB 5JB6A 2DDIA 1BF0A 3AUHA 8PTIA 1YKTB 3AUCA 1DTKA 2M01A 2ODYE 1CA0D 2FTMB 1FAKI 1LD6A 4Y0YI 4BQDA 1IRHA 1TOCR 5JB7A 3M7QB 1BUNB 1D0DB 3AUEA 2FI4I 1ZJDB 1BZ5A 4U30W 1BRCI 5PTIA 3TPII 2W8XA 3AUBA 1YC0I 2CA7A 3BYBA 1P2NB 1LD5A 4NTXB 1AALA 1UUAA 3D65I 2DDJA 1F5RI 6PTIA 4WXVC 3BTKI 9PTIA 1BZXI 1QLQA 1DEMA 1FY8I 3U1JE 3P92E 1T8MB 1P2MB 1KUNA 1NAGA 1G6XA 1KTHA 1OA65 1BPTA 2FI3I 4BD9B 1YLCB 3LDIA 1TFXC 1KNTA 1T8LB 3TGJI 2UUYB 2R9PE 5JB4A 3CI7A 1B0CA 2RA3C 3P95E 4DG4C 1BIKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OA5 5;  3OFW A;  2TGP I;  1P2I I;  1CO7 I;  4U32 X;  2KNT A;  3BTF I;  1CBW D;  1JC6 A;  4TPI I;  4ISL B;  3L33 E;  3BTH I;  3OTJ I;  4Y10 I;  3AUI A;  3BTG I;  1JV9 A;  1ZR0 B;  1EJM B;  1P2J I;  1TPA I;  3TGK I;  1T8N B;  2KCR A;  2PTC I;  4PTI A;  1D0D A;  2FTL I;  1BTH P;  3FP8 I;  1ADZ A;  1DTX A;  3BTT I;  1TCP A;  1UUB A;  4DTG K;  3GYM I;  3BTE I;  1YLD B;  2KAI I;  1BHC A;  2IJO I;  1BTI A;  1P2Q B;  3UOU B;  3TGI I;  7PTI A;  1TAP A;  3FP7 J;  4WWY C;  3T62 D;  4NTY B;  1JV8 A;  3UIR C;  3BTM I;  3LDJ A;  3FP6 I;  2ZVX A;  3BTW I;  5JB5 A;  2LFK A;  4Y11 I;  1T8O B;  2LFL A;  1DEN A;  3WNY A;  2TPI I;  1F7Z I;  3BTD I;  2HEX A;  1PIT A;  3BTQ I;  1KIG I;  1AAP A;  1K6U A;  4BNR I;  4ISO B;  4ISN B;  2JOT A;  1BPI A;  1BRB I;  1FAN A;  3AUD A;  1P2K I;  1TAW B;  2J6D A;  3L3T E;  2ZJX A;  3LDM A;  1MTN D;  3AUG A;  1SHP A;  1T7C B;  1Y62 A;  2M99 A;  4Y0Z I;  5C67 C;  2UUX A;  1EAW B;  2FI5 I;  4NTW B;  1P2O B;  5JB6 A;  2DDI A;  1BF0 A;  3AUH A;  8PTI A;  1YKT B;  3AUC A;  1DTK A;  2M01 A;  2ODY E;  1CA0 D;  2FTM B;  1FAK I;  1LD6 A;  4Y0Y I;  4BQD A;  1IRH A;  1TOC R;  5JB7 A;  3M7Q B;  1BUN B;  1D0D B;  3AUE A;  2FI4 I;  1ZJD B;  1BZ5 A;  4U30 W;  1BRC I;  5PTI A;  3TPI I;  2W8X A;  3AUB A;  1YC0 I;  2CA7 A;  3BYB A;  1P2N B;  1LD5 A;  4NTX B;  1AAL A;  1UUA A;  3D65 I;  2DDJ A;  1F5R I;  6PTI A;  4WXV C;  3BTK I;  9PTI A;  1BZX I;  1QLQ A;  1DEM A;  1FY8 I;  3U1J E;  3P92 E;  1T8M B;  1P2M B;  1KUN A;  1NAG A;  1G6X A;  1KTH A;  1OA6 5;  1BPT A;  2FI3 I;  4BD9 B;  1YLC B;  3LDI A;  1TFX C;  1KNT A;  1T8L B;  3TGJ I;  2UUY B;  2R9P E;  5JB4 A;  3CI7 A;  1B0C A;  2RA3 C;  3P95 E;  4DG4 C;  1BIK A; 
#chains in the Genus database with same CATH topology
 1OA5 5;  3OFW A;  2TGP I;  1P2I I;  1CO7 I;  4U32 X;  2KNT A;  3BTF I;  1CBW D;  1JC6 A;  4TPI I;  4ISL B;  3L33 E;  3BTH I;  3OTJ I;  4Y10 I;  3AUI A;  3BTG I;  1JV9 A;  1ZR0 B;  1EJM B;  1P2J I;  1TPA I;  3TGK I;  1T8N B;  2KCR A;  2PTC I;  4PTI A;  1D0D A;  2FTL I;  1BTH P;  3FP8 I;  1ADZ A;  1DTX A;  3BTT I;  1TCP A;  1UUB A;  4DTG K;  3GYM I;  3BTE I;  1YLD B;  2KAI I;  1BHC A;  2IJO I;  1BTI A;  1P2Q B;  3UOU B;  3TGI I;  7PTI A;  1TAP A;  3FP7 J;  4WWY C;  3T62 D;  4NTY B;  1JV8 A;  3UIR C;  3BTM I;  3LDJ A;  3FP6 I;  2ZVX A;  3BTW I;  5JB5 A;  2LFK A;  4Y11 I;  1T8O B;  2LFL A;  1DEN A;  3WNY A;  2TPI I;  1F7Z I;  3BTD I;  2HEX A;  1PIT A;  3BTQ I;  1KIG I;  1AAP A;  1K6U A;  4BNR I;  4ISO B;  4ISN B;  2JOT A;  1BPI A;  1BRB I;  1FAN A;  3AUD A;  1P2K I;  1TAW B;  2J6D A;  3L3T E;  2ZJX A;  3LDM A;  1MTN D;  3AUG A;  1SHP A;  1T7C B;  1Y62 A;  2M99 A;  4Y0Z I;  5C67 C;  2UUX A;  1EAW B;  2FI5 I;  4NTW B;  1P2O B;  5JB6 A;  2DDI A;  1BF0 A;  3AUH A;  8PTI A;  1YKT B;  3AUC A;  1DTK A;  2M01 A;  2ODY E;  1CA0 D;  2FTM B;  1FAK I;  1LD6 A;  4Y0Y I;  4BQD A;  1IRH A;  1TOC R;  5JB7 A;  3M7Q B;  1BUN B;  1D0D B;  3AUE A;  2FI4 I;  1ZJD B;  1BZ5 A;  4U30 W;  1BRC I;  5PTI A;  3TPI I;  2W8X A;  3AUB A;  1YC0 I;  2CA7 A;  3BYB A;  1P2N B;  1LD5 A;  4NTX B;  1AAL A;  1UUA A;  3D65 I;  2DDJ A;  1F5R I;  6PTI A;  4WXV C;  3BTK I;  9PTI A;  1BZX I;  1QLQ A;  1DEM A;  1FY8 I;  3U1J E;  3P92 E;  1T8M B;  1P2M B;  1KUN A;  1NAG A;  1G6X A;  1KTH A;  1OA6 5;  1BPT A;  2FI3 I;  4BD9 B;  1YLC B;  3LDI A;  1TFX C;  1KNT A;  1T8L B;  3TGJ I;  2UUY B;  2R9P E;  5JB4 A;  3CI7 A;  1B0C A;  2RA3 C;  3P95 E;  4DG4 C;  1BIK A; 
#chains in the Genus database with same CATH homology
 1OA5 5;  3OFW A;  2TGP I;  1P2I I;  1CO7 I;  4U32 X;  2KNT A;  3BTF I;  1CBW D;  1JC6 A;  4TPI I;  4ISL B;  3L33 E;  3BTH I;  3OTJ I;  4Y10 I;  3AUI A;  3BTG I;  1JV9 A;  1ZR0 B;  1EJM B;  1P2J I;  1TPA I;  3TGK I;  1T8N B;  2KCR A;  2PTC I;  4PTI A;  1D0D A;  2FTL I;  1BTH P;  3FP8 I;  1ADZ A;  1DTX A;  3BTT I;  1TCP A;  1UUB A;  4DTG K;  3GYM I;  3BTE I;  1YLD B;  2KAI I;  1BHC A;  2IJO I;  1BTI A;  1P2Q B;  3UOU B;  3TGI I;  7PTI A;  1TAP A;  3FP7 J;  4WWY C;  3T62 D;  4NTY B;  1JV8 A;  3UIR C;  3BTM I;  3LDJ A;  3FP6 I;  2ZVX A;  3BTW I;  5JB5 A;  2LFK A;  4Y11 I;  1T8O B;  2LFL A;  1DEN A;  3WNY A;  2TPI I;  1F7Z I;  3BTD I;  2HEX A;  1PIT A;  3BTQ I;  1KIG I;  1AAP A;  1K6U A;  4BNR I;  4ISO B;  4ISN B;  2JOT A;  1BPI A;  1BRB I;  1FAN A;  3AUD A;  1P2K I;  1TAW B;  2J6D A;  3L3T E;  2ZJX A;  3LDM A;  1MTN D;  3AUG A;  1SHP A;  1T7C B;  1Y62 A;  2M99 A;  4Y0Z I;  5C67 C;  2UUX A;  1EAW B;  2FI5 I;  4NTW B;  1P2O B;  5JB6 A;  2DDI A;  1BF0 A;  3AUH A;  8PTI A;  1YKT B;  3AUC A;  1DTK A;  2M01 A;  2ODY E;  1CA0 D;  2FTM B;  1FAK I;  1LD6 A;  4Y0Y I;  4BQD A;  1IRH A;  1TOC R;  5JB7 A;  3M7Q B;  1BUN B;  1D0D B;  3AUE A;  2FI4 I;  1ZJD B;  1BZ5 A;  4U30 W;  1BRC I;  5PTI A;  3TPI I;  2W8X A;  3AUB A;  1YC0 I;  2CA7 A;  3BYB A;  1P2N B;  1LD5 A;  4NTX B;  1AAL A;  1UUA A;  3D65 I;  2DDJ A;  1F5R I;  6PTI A;  4WXV C;  3BTK I;  9PTI A;  1BZX I;  1QLQ A;  1DEM A;  1FY8 I;  3U1J E;  3P92 E;  1T8M B;  1P2M B;  1KUN A;  1NAG A;  1G6X A;  1KTH A;  1OA6 5;  1BPT A;  2FI3 I;  4BD9 B;  1YLC B;  3LDI A;  1TFX C;  1KNT A;  1T8L B;  3TGJ I;  2UUY B;  2R9P E;  5JB4 A;  3CI7 A;  1B0C A;  2RA3 C;  3P95 E;  4DG4 C;  1BIK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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