3CI7A

Crystal structure of a simplified bpti containing 20 alanines
Total Genus 8
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
8
sequence length
58
structure length
58
Chain Sequence
RPAFCLEPPYAGPGKARIIRYFYNAAAGAAQAFVYGGARAKRNNFASAADALAACAAA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of an extensively simplified variant of bovine pancreatic trypsin inhibitor in which over one-third of the residues are alanines
pubmed doi rcsb
molecule tags Hydrolase inhibitor
molecule keywords bovine pancreatic trypsin inhibitor
total genus 8
structure length 58
sequence length 58
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-03-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.410.10 Few Secondary Structures Irregular Factor Xa Inhibitor Pancreatic trypsin inhibitor Kunitz domain 3ci7A00
1UUBA 4U32X 2FI3I 4DG4C 1DTXA 1SHPA 2LFKA 3FP6I 1ADZA 2UUYB 3BTEI 3UIRC 4PTIA 4NTYB 1QLQA 1K6UA 1KUNA 1T8MB 2M01A 2ZJXA 4WWYC 1BIKA 5JB6A 1MTND 3TGJI 2ZVXA 3BTWI 2DDJA 1TAPA 1KTHA 3TGII 1FAKI 3M7QB 2KAII 2M99A 4BNRI 4BD9B 1BRCI 1BPTA 2J6DA 3GYMI 1OA55 3BTTI 3FP8I 1BZXI 1B0CA 1ZJDB 2TPII 2KCRA 1BRBI 1TPAI 3AUCA 3P92E 1BPIA 2KNTA 1D0DB 3CI7A 1P2OB 4ISNB 5JB5A 1T7CB 7PTIA 4NTWB 2IJOI 4Y10I 3AUBA 4ISLB 1AAPA 4NTXB 4Y11I 3T62D 1KNTA 1BTIA 1BTHP 1CBWD 1T8LB 1TAWB 4DTGK 1ZR0B 1KIGI 5JB7A 1TOCR 3L33E 1YLDB 3AUEA 1JV8A 1BF0A 3OFWA 3OTJI 1T8NB 2CA7A 1P2KI 3BTHI 3BTQI 2R9PE 1P2II 1P2QB 2HEXA 3U1JE 3BTMI 2JOTA 2LFLA 2UUXA 3WNYA 2DDIA 1TCPA 1F7ZI 1BUNB 1OA65 5JB4A 2W8XA 3LDIA 1DEMA 1FANA 1JC6A 3AUIA 8PTIA 3BTDI 1Y62A 1G6XA 4U30W 1P2MB 1UUAA 2FTMB 1YC0I 4BQDA 3D65I 1YKTB 1F5RI 1BHCA 3TPII 6PTIA 4WXVC 3BTGI 1JV9A 1LD5A 2FTLI 3LDJA 3TGKI 1EJMB 2ODYE 1DTKA 3AUGA 2FI4I 3BTFI 3LDMA 1BZ5A 1LD6A 1D0DA 2PTCI 3BYBA 1PITA 3AUDA 3AUHA 4Y0YI 3P95E 5C67C 1TFXC 4Y0ZI 1AALA 3L3TE 1IRHA 1NAGA 2RA3C 3UOUB 3BTKI 2TGPI 5PTIA 1DENA 2FI5I 4ISOB 9PTIA 1CA0D 3FP7J 1P2JI 1YLCB 1T8OB 1EAWB 1P2NB 1CO7I 1FY8I 4TPII
chains in the Genus database with same CATH superfamily
1UUBA 4U32X 2FI3I 4DG4C 1DTXA 1SHPA 2LFKA 3FP6I 1ADZA 2UUYB 3BTEI 3UIRC 4PTIA 4NTYB 1QLQA 1K6UA 1KUNA 1T8MB 2M01A 2ZJXA 4WWYC 1BIKA 5JB6A 1MTND 3TGJI 2ZVXA 3BTWI 2DDJA 1TAPA 1KTHA 3TGII 1FAKI 3M7QB 2KAII 2M99A 4BNRI 4BD9B 1BRCI 1BPTA 2J6DA 3GYMI 1OA55 3BTTI 3FP8I 1BZXI 1B0CA 1ZJDB 2TPII 2KCRA 1BRBI 1TPAI 3AUCA 3P92E 1BPIA 2KNTA 1D0DB 3CI7A 1P2OB 4ISNB 5JB5A 1T7CB 7PTIA 4NTWB 2IJOI 4Y10I 3AUBA 4ISLB 1AAPA 4NTXB 4Y11I 3T62D 1KNTA 1BTIA 1BTHP 1CBWD 1T8LB 1TAWB 4DTGK 1ZR0B 1KIGI 5JB7A 1TOCR 3L33E 1YLDB 3AUEA 1JV8A 1BF0A 3OFWA 3OTJI 1T8NB 2CA7A 1P2KI 3BTHI 3BTQI 2R9PE 1P2II 1P2QB 2HEXA 3U1JE 3BTMI 2JOTA 2LFLA 2UUXA 3WNYA 2DDIA 1TCPA 1F7ZI 1BUNB 1OA65 5JB4A 2W8XA 3LDIA 1DEMA 1FANA 1JC6A 3AUIA 8PTIA 3BTDI 1Y62A 1G6XA 4U30W 1P2MB 1UUAA 2FTMB 1YC0I 4BQDA 3D65I 1YKTB 1F5RI 1BHCA 3TPII 6PTIA 4WXVC 3BTGI 1JV9A 1LD5A 2FTLI 3LDJA 3TGKI 1EJMB 2ODYE 1DTKA 3AUGA 2FI4I 3BTFI 3LDMA 1BZ5A 1LD6A 1D0DA 2PTCI 3BYBA 1PITA 3AUDA 3AUHA 4Y0YI 3P95E 5C67C 1TFXC 4Y0ZI 1AALA 3L3TE 1IRHA 1NAGA 2RA3C 3UOUB 3BTKI 2TGPI 5PTIA 1DENA 2FI5I 4ISOB 9PTIA 1CA0D 3FP7J 1P2JI 1YLCB 1T8OB 1EAWB 1P2NB 1CO7I 1FY8I 4TPII
chains in the Genus database with same CATH topology
1UUBA 4U32X 2FI3I 4DG4C 1DTXA 1SHPA 2LFKA 3FP6I 1ADZA 2UUYB 3BTEI 3UIRC 4PTIA 4NTYB 1QLQA 1K6UA 1KUNA 1T8MB 2M01A 2ZJXA 4WWYC 1BIKA 5JB6A 1MTND 3TGJI 2ZVXA 3BTWI 2DDJA 1TAPA 1KTHA 3TGII 1FAKI 3M7QB 2KAII 2M99A 4BNRI 4BD9B 1BRCI 1BPTA 2J6DA 3GYMI 1OA55 3BTTI 3FP8I 1BZXI 1B0CA 1ZJDB 2TPII 2KCRA 1BRBI 1TPAI 3AUCA 3P92E 1BPIA 2KNTA 1D0DB 3CI7A 1P2OB 4ISNB 5JB5A 1T7CB 7PTIA 4NTWB 2IJOI 4Y10I 3AUBA 4ISLB 1AAPA 4NTXB 4Y11I 3T62D 1KNTA 1BTIA 1BTHP 1CBWD 1T8LB 1TAWB 4DTGK 1ZR0B 1KIGI 5JB7A 1TOCR 3L33E 1YLDB 3AUEA 1JV8A 1BF0A 3OFWA 3OTJI 1T8NB 2CA7A 1P2KI 3BTHI 3BTQI 2R9PE 1P2II 1P2QB 2HEXA 3U1JE 3BTMI 2JOTA 2LFLA 2UUXA 3WNYA 2DDIA 1TCPA 1F7ZI 1BUNB 1OA65 5JB4A 2W8XA 3LDIA 1DEMA 1FANA 1JC6A 3AUIA 8PTIA 3BTDI 1Y62A 1G6XA 4U30W 1P2MB 1UUAA 2FTMB 1YC0I 4BQDA 3D65I 1YKTB 1F5RI 1BHCA 3TPII 6PTIA 4WXVC 3BTGI 1JV9A 1LD5A 2FTLI 3LDJA 3TGKI 1EJMB 2ODYE 1DTKA 3AUGA 2FI4I 3BTFI 3LDMA 1BZ5A 1LD6A 1D0DA 2PTCI 3BYBA 1PITA 3AUDA 3AUHA 4Y0YI 3P95E 5C67C 1TFXC 4Y0ZI 1AALA 3L3TE 1IRHA 1NAGA 2RA3C 3UOUB 3BTKI 2TGPI 5PTIA 1DENA 2FI5I 4ISOB 9PTIA 1CA0D 3FP7J 1P2JI 1YLCB 1T8OB 1EAWB 1P2NB 1CO7I 1FY8I 4TPII
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UUB A;  4U32 X;  2FI3 I;  4DG4 C;  1DTX A;  1SHP A;  2LFK A;  3FP6 I;  1ADZ A;  2UUY B;  3BTE I;  3UIR C;  4PTI A;  4NTY B;  1QLQ A;  1K6U A;  1KUN A;  1T8M B;  2M01 A;  2ZJX A;  4WWY C;  1BIK A;  5JB6 A;  1MTN D;  3TGJ I;  2ZVX A;  3BTW I;  2DDJ A;  1TAP A;  1KTH A;  3TGI I;  1FAK I;  3M7Q B;  2KAI I;  2M99 A;  4BNR I;  4BD9 B;  1BRC I;  1BPT A;  2J6D A;  3GYM I;  1OA5 5;  3BTT I;  3FP8 I;  1BZX I;  1B0C A;  1ZJD B;  2TPI I;  2KCR A;  1BRB I;  1TPA I;  3AUC A;  3P92 E;  1BPI A;  2KNT A;  1D0D B;  3CI7 A;  1P2O B;  4ISN B;  5JB5 A;  1T7C B;  7PTI A;  4NTW B;  2IJO I;  4Y10 I;  3AUB A;  4ISL B;  1AAP A;  4NTX B;  4Y11 I;  3T62 D;  1KNT A;  1BTI A;  1BTH P;  1CBW D;  1T8L B;  1TAW B;  4DTG K;  1ZR0 B;  1KIG I;  5JB7 A;  1TOC R;  3L33 E;  1YLD B;  3AUE A;  1JV8 A;  1BF0 A;  3OFW A;  3OTJ I;  1T8N B;  2CA7 A;  1P2K I;  3BTH I;  3BTQ I;  2R9P E;  1P2I I;  1P2Q B;  2HEX A;  3U1J E;  3BTM I;  2JOT A;  2LFL A;  2UUX A;  3WNY A;  2DDI A;  1TCP A;  1F7Z I;  1BUN B;  1OA6 5;  5JB4 A;  2W8X A;  3LDI A;  1DEM A;  1FAN A;  1JC6 A;  3AUI A;  8PTI A;  3BTD I;  1Y62 A;  1G6X A;  4U30 W;  1P2M B;  1UUA A;  2FTM B;  1YC0 I;  4BQD A;  3D65 I;  1YKT B;  1F5R I;  1BHC A;  3TPI I;  6PTI A;  4WXV C;  3BTG I;  1JV9 A;  1LD5 A;  2FTL I;  3LDJ A;  3TGK I;  1EJM B;  2ODY E;  1DTK A;  3AUG A;  2FI4 I;  3BTF I;  3LDM A;  1BZ5 A;  1LD6 A;  1D0D A;  2PTC I;  3BYB A;  1PIT A;  3AUD A;  3AUH A;  4Y0Y I;  3P95 E;  5C67 C;  1TFX C;  4Y0Z I;  1AAL A;  3L3T E;  1IRH A;  1NAG A;  2RA3 C;  3UOU B;  3BTK I;  2TGP I;  5PTI A;  1DEN A;  2FI5 I;  4ISO B;  9PTI A;  1CA0 D;  3FP7 J;  1P2J I;  1YLC B;  1T8O B;  1EAW B;  1P2N B;  1CO7 I;  1FY8 I;  4TPI I; 
#chains in the Genus database with same CATH topology
 1UUB A;  4U32 X;  2FI3 I;  4DG4 C;  1DTX A;  1SHP A;  2LFK A;  3FP6 I;  1ADZ A;  2UUY B;  3BTE I;  3UIR C;  4PTI A;  4NTY B;  1QLQ A;  1K6U A;  1KUN A;  1T8M B;  2M01 A;  2ZJX A;  4WWY C;  1BIK A;  5JB6 A;  1MTN D;  3TGJ I;  2ZVX A;  3BTW I;  2DDJ A;  1TAP A;  1KTH A;  3TGI I;  1FAK I;  3M7Q B;  2KAI I;  2M99 A;  4BNR I;  4BD9 B;  1BRC I;  1BPT A;  2J6D A;  3GYM I;  1OA5 5;  3BTT I;  3FP8 I;  1BZX I;  1B0C A;  1ZJD B;  2TPI I;  2KCR A;  1BRB I;  1TPA I;  3AUC A;  3P92 E;  1BPI A;  2KNT A;  1D0D B;  3CI7 A;  1P2O B;  4ISN B;  5JB5 A;  1T7C B;  7PTI A;  4NTW B;  2IJO I;  4Y10 I;  3AUB A;  4ISL B;  1AAP A;  4NTX B;  4Y11 I;  3T62 D;  1KNT A;  1BTI A;  1BTH P;  1CBW D;  1T8L B;  1TAW B;  4DTG K;  1ZR0 B;  1KIG I;  5JB7 A;  1TOC R;  3L33 E;  1YLD B;  3AUE A;  1JV8 A;  1BF0 A;  3OFW A;  3OTJ I;  1T8N B;  2CA7 A;  1P2K I;  3BTH I;  3BTQ I;  2R9P E;  1P2I I;  1P2Q B;  2HEX A;  3U1J E;  3BTM I;  2JOT A;  2LFL A;  2UUX A;  3WNY A;  2DDI A;  1TCP A;  1F7Z I;  1BUN B;  1OA6 5;  5JB4 A;  2W8X A;  3LDI A;  1DEM A;  1FAN A;  1JC6 A;  3AUI A;  8PTI A;  3BTD I;  1Y62 A;  1G6X A;  4U30 W;  1P2M B;  1UUA A;  2FTM B;  1YC0 I;  4BQD A;  3D65 I;  1YKT B;  1F5R I;  1BHC A;  3TPI I;  6PTI A;  4WXV C;  3BTG I;  1JV9 A;  1LD5 A;  2FTL I;  3LDJ A;  3TGK I;  1EJM B;  2ODY E;  1DTK A;  3AUG A;  2FI4 I;  3BTF I;  3LDM A;  1BZ5 A;  1LD6 A;  1D0D A;  2PTC I;  3BYB A;  1PIT A;  3AUD A;  3AUH A;  4Y0Y I;  3P95 E;  5C67 C;  1TFX C;  4Y0Z I;  1AAL A;  3L3T E;  1IRH A;  1NAG A;  2RA3 C;  3UOU B;  3BTK I;  2TGP I;  5PTI A;  1DEN A;  2FI5 I;  4ISO B;  9PTI A;  1CA0 D;  3FP7 J;  1P2J I;  1YLC B;  1T8O B;  1EAW B;  1P2N B;  1CO7 I;  1FY8 I;  4TPI I; 
#chains in the Genus database with same CATH homology
 1UUB A;  4U32 X;  2FI3 I;  4DG4 C;  1DTX A;  1SHP A;  2LFK A;  3FP6 I;  1ADZ A;  2UUY B;  3BTE I;  3UIR C;  4PTI A;  4NTY B;  1QLQ A;  1K6U A;  1KUN A;  1T8M B;  2M01 A;  2ZJX A;  4WWY C;  1BIK A;  5JB6 A;  1MTN D;  3TGJ I;  2ZVX A;  3BTW I;  2DDJ A;  1TAP A;  1KTH A;  3TGI I;  1FAK I;  3M7Q B;  2KAI I;  2M99 A;  4BNR I;  4BD9 B;  1BRC I;  1BPT A;  2J6D A;  3GYM I;  1OA5 5;  3BTT I;  3FP8 I;  1BZX I;  1B0C A;  1ZJD B;  2TPI I;  2KCR A;  1BRB I;  1TPA I;  3AUC A;  3P92 E;  1BPI A;  2KNT A;  1D0D B;  3CI7 A;  1P2O B;  4ISN B;  5JB5 A;  1T7C B;  7PTI A;  4NTW B;  2IJO I;  4Y10 I;  3AUB A;  4ISL B;  1AAP A;  4NTX B;  4Y11 I;  3T62 D;  1KNT A;  1BTI A;  1BTH P;  1CBW D;  1T8L B;  1TAW B;  4DTG K;  1ZR0 B;  1KIG I;  5JB7 A;  1TOC R;  3L33 E;  1YLD B;  3AUE A;  1JV8 A;  1BF0 A;  3OFW A;  3OTJ I;  1T8N B;  2CA7 A;  1P2K I;  3BTH I;  3BTQ I;  2R9P E;  1P2I I;  1P2Q B;  2HEX A;  3U1J E;  3BTM I;  2JOT A;  2LFL A;  2UUX A;  3WNY A;  2DDI A;  1TCP A;  1F7Z I;  1BUN B;  1OA6 5;  5JB4 A;  2W8X A;  3LDI A;  1DEM A;  1FAN A;  1JC6 A;  3AUI A;  8PTI A;  3BTD I;  1Y62 A;  1G6X A;  4U30 W;  1P2M B;  1UUA A;  2FTM B;  1YC0 I;  4BQD A;  3D65 I;  1YKT B;  1F5R I;  1BHC A;  3TPI I;  6PTI A;  4WXV C;  3BTG I;  1JV9 A;  1LD5 A;  2FTL I;  3LDJ A;  3TGK I;  1EJM B;  2ODY E;  1DTK A;  3AUG A;  2FI4 I;  3BTF I;  3LDM A;  1BZ5 A;  1LD6 A;  1D0D A;  2PTC I;  3BYB A;  1PIT A;  3AUD A;  3AUH A;  4Y0Y I;  3P95 E;  5C67 C;  1TFX C;  4Y0Z I;  1AAL A;  3L3T E;  1IRH A;  1NAG A;  2RA3 C;  3UOU B;  3BTK I;  2TGP I;  5PTI A;  1DEN A;  2FI5 I;  4ISO B;  9PTI A;  1CA0 D;  3FP7 J;  1P2J I;  1YLC B;  1T8O B;  1EAW B;  1P2N B;  1CO7 I;  1FY8 I;  4TPI I; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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