3FKIE

12-subunit rna polymerase ii refined with zn-sad data
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
214
structure length
214
Chain Sequence
DQENERNISRLWRAFRTVKEMVKDRGYFITQEEVELPLEDFKAKYCDSMGRPQRKMMSFQANPTEESISKFPDMGSLWVEFCDEPSVGVKTMKTFVIHIQEKNFQTGIFVYQNNITPSAMKLVPSIPPATIETFNEAALVVNITHHELVPKHIRLSSDEKRELLKRYRLKESQLPRIQRADPVALYLGLKRGEVVKIIRKSETSGRYASYRICM
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 39
structure length 214
sequence length 214
ec nomenclature
pdb deposition date 2008-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
E PF01191 RNA_pol_Rpb5_C RNA polymerase Rpb5, C-terminal domain
E PF03871 RNA_pol_Rpb5_N RNA polymerase Rpb5, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1340.10 Alpha Beta 3-Layer(aba) Sandwich Dna-directed Rna Polymerases I, Ii, And Iii 27 Kd Polypeptide; Chain: A; domain 1 RNA polymerase, Rpb5, N-terminal domain 3fkiE01
3.90.940.20 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit RPB5-like RNA polymerase subunit 3fkiE02
1I50E 5M3ME 4A3EE 4BXXE 4C2ME 2E2JE 2JA8E 3FKIE 3CQZE 5C3EE 4AYBH 2E2IE 2E2HE 4X6AE 1TWAE 3GTPE 4BBSE 1R9TE 4A3KE 1I6HE 4A3DE 5M5XE 1Y1WE 4BY7E 1WCME 3K7AE 3M4OE 3H3VF 4A3LE 3S1ME 2JA7E 4A3BE 3S14E 2R7ZE 4Y7NE 4QIWH 4A3GE 3PO2E 4C3IE 3GTOE 1I3QE 5FJ8E 3S2HE 3GTGE 4A93E 5C44E 2B63E 5M5YE 4A3JE 2NVYE 3S1NE 4Y52E 5C4JE 3GTKE 3GTLE 1K83E 4A3FE 1Y1VE 2R92E 2NVTE 1TWCE 3HOZE 2WAQH 4BBRE 1TWFE 3S17E 3S1QE 2VUME 3I4NE 3PO3E 1DZFA 5FLME 2WB1H 3S15E 4C3HE 2JA6E 2NVXE 5C4XE 1TWGE 5IP7E 3HOYE 3S1RE 5IYCE 3HOXE 3S16E 1SFOE 3GTME 3I4ME 3HOUE 2R93E 4A3IE 3RZOE 4BY1E 3GTJE 5IYBE 2NVQE 3H0GE 4A3CE 1EIKA 3M3YE 5IYDE 3HKZH 5IP9E 4A3ME 4C3JE 3GTQE 2YU9E 2PMZH 3S2DE 5M5WE 3HOWE 2Y0SH 1TWHE 5M3FE 3HOVE 2JA5E 3RZDE
chains in the Genus database with same CATH superfamily
5IP9F 1I50E 5M3ME 4A3MF 4A3EE 4C3JF 4BXXE 4C2ME 4QIWK 2YU9F 3S2DF 4G7OE 2E2JE 2JA8E 3FKIE 4MEYE 1TWHF 3CQZE 5C3EE 4AYBH 2E2IE 2E2HE 4X6AE 1TWAE 2NVXF 4LK0E 3HOVF 5C4XF 2JA5F 3RZDF 3HOYF 3GTPE 4BBSE 1R9TE 4A3KE 1I6HE 1I50F 5M3MF 4A3DE 5M5XE 1Y1WE 4A3EF 5D4CE 4BXXF 4C2MF 4BY7E 3HOXF 1WCME 3GTMF 3I4MF 5D4DE 3K7AE 3M4OE 3H3VF 2E2JF 4GZYE 3FKIF 2A6HE 4A3LE 3S1ME 2WAQK 2JA7E 4A3BE 5C3EF 3H0GF 4Q4ZE 2E2HF 1TWAF 4A3CF 4X6AF 4LJZE 4KN4E 2WB1I 3S14E 2Y0SI 3GTPF 2R7ZE 1R9TF 4A3KF 1I6HF 3GTQF 4BBSF 5M5XF 4Y7NE 5M5WF 4QIWH 4A3GE 3PO2E 4C3IE 3GTOE 1I3QE 5FJ8E 1WCMF 3S2HE 4OIPE 3K7AF 3HOWF 3GTGE 2A6EE 1ZYRE 4A93E 4LK1E 5M3FF 4OIQE 5C44E 4A3LF 2CW0E 2B63E 5M5YE 4A3JE 4YFKE 4A3BF 2NVYE 3S1NE 1YNJK 4Y52E 1IW7E 5C4JE 3GTKE 3S14F 4Q5SE 2R7ZF 4XSXE 4JK1E 2A69E 4A3GF 3PO2F 3GTOF 3GTLE 1K83E 4A3FE 1Y1VE 2R92E 1I3QF 4LLGE 5FJ8F 2JA8F 2NVTE 2BE5E 1TWCE 1QKLA 4KN7E 3S2HF 3CQZF 5D4EE 3HOZE 4A93F 2E2IF 2WAQH 5C44F 4BBRE 2B63F 5M5YF 1TWFE 5E18E 4A3JF 3S17E 2NVYF 3S1NF 3S1QE 4A3DF 3HKZK 1Y1WF 5C4JF 2O5JE 4BY7F 4YG2E 2VUME 1I6VE 2PMZK 3M4OF 5E17E 3GTLF 1K83F 4A3FF 1Y1VF 4OIRE 2R92F 3I4NE 1SMYE 2NVTF 3PO3E 1TWCF 3S1MF 2JA7F 3HOZF 1DZFA 5FLME 2WB1H 3S15E 1TWFF 4C3HE 1HQME 3S17F 2JA6E 3WODE 3S1QF 2NVXE 3EQLE 5TMFE 5C4XE 4Y7NF 1TWGE 2A68E 5IYDF 5IP7E 3HOYE 4C3IF 2O5IE 4ZH4E 4XLNE 2VUMF 3S1RE 3GTGF 5IYCE 3HOXE 4XLPE 3H3VG 2KRXA 3S16E 3I4NF 1SFOE 3GTME 3I4ME 3HOUE 2R93E 3PO3F 4A3IE 3RZOE 4BY1E 5FLMF 3GTJE 4AYBK 3S15F 4G7ZE 4Y52F 5IYBE 4C3HF 2NVQE 2PPBE 2JA6F 3GTKF 3H0GE 4XSZE 4A3CE 5TMCE 1EIKA 3M3YE 5IYDE 3HKZH 5IP9E 1TWGF 4MQ9E 4A3ME 4C3JE 5IP7F 3GTQE 2YU9E 3DXJE 2PMZH 4G7HE 3S2DE 5BYHE 3S1RF 5M5WE 5IYCF 3S16F 1SFOF 3HOUF 2R93F 3HOWE 2Y0SH 4BBRF 4A3IF 1TWHE 4BY1F 3RZOF 3GTJF 5M3FE 3HOVE 5IYBF 4OINE 1YNNK 4MEXE 2NVQF 2JA5E 3RZDE 4KMUE 5IPLE 4YFXE 3M3YF 4YFNE 4OIOE
chains in the Genus database with same CATH topology
1I50E 5M3ME 4A3EE 4BXXE 4C2ME 2E2JE 2JA8E 3FKIE 3CQZE 5C3EE 4AYBH 2E2IE 2E2HE 4X6AE 1TWAE 3GTPE 4BBSE 1R9TE 4A3KE 1I6HE 4A3DE 5M5XE 1Y1WE 4BY7E 1WCME 3K7AE 3M4OE 3H3VF 4A3LE 3S1ME 2JA7E 4A3BE 3S14E 2R7ZE 4Y7NE 4QIWH 4A3GE 3PO2E 4C3IE 3GTOE 1I3QE 5FJ8E 3S2HE 3GTGE 4A93E 5C44E 2B63E 5M5YE 4A3JE 2NVYE 3S1NE 4Y52E 5C4JE 3GTKE 3GTLE 1K83E 4A3FE 1Y1VE 2R92E 2NVTE 1TWCE 3HOZE 2WAQH 4BBRE 1TWFE 3S17E 3S1QE 2VUME 3I4NE 3PO3E 1DZFA 5FLME 2WB1H 3S15E 4C3HE 2JA6E 2NVXE 5C4XE 1TWGE 5IP7E 3HOYE 3S1RE 5IYCE 3HOXE 3S16E 1SFOE 3GTME 3I4ME 3HOUE 2R93E 4A3IE 3RZOE 4BY1E 3GTJE 5IYBE 2NVQE 3H0GE 4A3CE 1EIKA 3M3YE 5IYDE 3HKZH 5IP9E 4A3ME 4C3JE 3GTQE 2YU9E 2PMZH 3S2DE 5M5WE 3HOWE 2Y0SH 1TWHE 5M3FE 3HOVE 2JA5E 3RZDE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1I50 E;  5M3M E;  4A3E E;  4BXX E;  4C2M E;  2E2J E;  2JA8 E;  3FKI E;  3CQZ E;  5C3E E;  4AYB H;  2E2I E;  2E2H E;  4X6A E;  1TWA E;  3GTP E;  4BBS E;  1R9T E;  4A3K E;  1I6H E;  4A3D E;  5M5X E;  1Y1W E;  4BY7 E;  1WCM E;  3K7A E;  3M4O E;  3H3V F;  4A3L E;  3S1M E;  2JA7 E;  4A3B E;  3S14 E;  2R7Z E;  4Y7N E;  4QIW H;  4A3G E;  3PO2 E;  4C3I E;  3GTO E;  1I3Q E;  5FJ8 E;  3S2H E;  3GTG E;  4A93 E;  5C44 E;  2B63 E;  5M5Y E;  4A3J E;  2NVY E;  3S1N E;  4Y52 E;  5C4J E;  3GTK E;  3GTL E;  1K83 E;  4A3F E;  1Y1V E;  2R92 E;  2NVT E;  1TWC E;  3HOZ E;  2WAQ H;  4BBR E;  1TWF E;  3S17 E;  3S1Q E;  2VUM E;  3I4N E;  3PO3 E;  1DZF A;  5FLM E;  2WB1 H;  3S15 E;  4C3H E;  2JA6 E;  2NVX E;  5C4X E;  1TWG E;  5IP7 E;  3HOY E;  3S1R E;  5IYC E;  3HOX E;  3S16 E;  1SFO E;  3GTM E;  3I4M E;  3HOU E;  2R93 E;  4A3I E;  3RZO E;  4BY1 E;  3GTJ E;  5IYB E;  2NVQ E;  3H0G E;  4A3C E;  1EIK A;  3M3Y E;  5IYD E;  3HKZ H;  5IP9 E;  4A3M E;  4C3J E;  3GTQ E;  2YU9 E;  2PMZ H;  3S2D E;  5M5W E;  3HOW E;  2Y0S H;  1TWH E;  5M3F E;  3HOV E;  2JA5 E;  3RZD E; 
#chains in the Genus database with same CATH topology
 5IP9 F;  1I50 E;  5M3M E;  4A3M F;  4A3E E;  4C3J F;  4BXX E;  4C2M E;  4QIW K;  2YU9 F;  3S2D F;  4G7O E;  2E2J E;  2JA8 E;  3FKI E;  4MEY E;  1TWH F;  3CQZ E;  5C3E E;  4AYB H;  2E2I E;  2E2H E;  4X6A E;  1TWA E;  2NVX F;  4LK0 E;  3HOV F;  5C4X F;  2JA5 F;  3RZD F;  3HOY F;  3GTP E;  4BBS E;  1R9T E;  4A3K E;  1I6H E;  1I50 F;  5M3M F;  4A3D E;  5M5X E;  1Y1W E;  4A3E F;  5D4C E;  4BXX F;  4C2M F;  4BY7 E;  3HOX F;  1WCM E;  3GTM F;  3I4M F;  5D4D E;  3K7A E;  3M4O E;  3H3V F;  2E2J F;  4GZY E;  3FKI F;  2A6H E;  4A3L E;  3S1M E;  2WAQ K;  2JA7 E;  4A3B E;  5C3E F;  3H0G F;  4Q4Z E;  2E2H F;  1TWA F;  4A3C F;  4X6A F;  4LJZ E;  4KN4 E;  2WB1 I;  3S14 E;  2Y0S I;  3GTP F;  2R7Z E;  1R9T F;  4A3K F;  1I6H F;  3GTQ F;  4BBS F;  5M5X F;  4Y7N E;  5M5W F;  4QIW H;  4A3G E;  3PO2 E;  4C3I E;  3GTO E;  1I3Q E;  5FJ8 E;  1WCM F;  3S2H E;  4OIP E;  3K7A F;  3HOW F;  3GTG E;  2A6E E;  1ZYR E;  4A93 E;  4LK1 E;  5M3F F;  4OIQ E;  5C44 E;  4A3L F;  2CW0 E;  2B63 E;  5M5Y E;  4A3J E;  4YFK E;  4A3B F;  2NVY E;  3S1N E;  1YNJ K;  4Y52 E;  1IW7 E;  5C4J E;  3GTK E;  3S14 F;  4Q5S E;  2R7Z F;  4XSX E;  4JK1 E;  2A69 E;  4A3G F;  3PO2 F;  3GTO F;  3GTL E;  1K83 E;  4A3F E;  1Y1V E;  2R92 E;  1I3Q F;  4LLG E;  5FJ8 F;  2JA8 F;  2NVT E;  2BE5 E;  1TWC E;  1QKL A;  4KN7 E;  3S2H F;  3CQZ F;  5D4E E;  3HOZ E;  4A93 F;  2E2I F;  2WAQ H;  5C44 F;  4BBR E;  2B63 F;  5M5Y F;  1TWF E;  5E18 E;  4A3J F;  3S17 E;  2NVY F;  3S1N F;  3S1Q E;  4A3D F;  3HKZ K;  1Y1W F;  5C4J F;  2O5J E;  4BY7 F;  4YG2 E;  2VUM E;  1I6V E;  2PMZ K;  3M4O F;  5E17 E;  3GTL F;  1K83 F;  4A3F F;  1Y1V F;  4OIR E;  2R92 F;  3I4N E;  1SMY E;  2NVT F;  3PO3 E;  1TWC F;  3S1M F;  2JA7 F;  3HOZ F;  1DZF A;  5FLM E;  2WB1 H;  3S15 E;  1TWF F;  4C3H E;  1HQM E;  3S17 F;  2JA6 E;  3WOD E;  3S1Q F;  2NVX E;  3EQL E;  5TMF E;  5C4X E;  4Y7N F;  1TWG E;  2A68 E;  5IYD F;  5IP7 E;  3HOY E;  4C3I F;  2O5I E;  4ZH4 E;  4XLN E;  2VUM F;  3S1R E;  3GTG F;  5IYC E;  3HOX E;  4XLP E;  3H3V G;  2KRX A;  3S16 E;  3I4N F;  1SFO E;  3GTM E;  3I4M E;  3HOU E;  2R93 E;  3PO3 F;  4A3I E;  3RZO E;  4BY1 E;  5FLM F;  3GTJ E;  4AYB K;  3S15 F;  4G7Z E;  4Y52 F;  5IYB E;  4C3H F;  2NVQ E;  2PPB E;  2JA6 F;  3GTK F;  3H0G E;  4XSZ E;  4A3C E;  5TMC E;  1EIK A;  3M3Y E;  5IYD E;  3HKZ H;  5IP9 E;  1TWG F;  4MQ9 E;  4A3M E;  4C3J E;  5IP7 F;  3GTQ E;  2YU9 E;  3DXJ E;  2PMZ H;  4G7H E;  3S2D E;  5BYH E;  3S1R F;  5M5W E;  5IYC F;  3S16 F;  1SFO F;  3HOU F;  2R93 F;  3HOW E;  2Y0S H;  4BBR F;  4A3I F;  1TWH E;  4BY1 F;  3RZO F;  3GTJ F;  5M3F E;  3HOV E;  5IYB F;  4OIN E;  1YNN K;  4MEX E;  2NVQ F;  2JA5 E;  3RZD E;  4KMU E;  5IPL E;  4YFX E;  3M3Y F;  4YFN E;  4OIO E; 
#chains in the Genus database with same CATH homology
 1I50 E;  5M3M E;  4A3E E;  4BXX E;  4C2M E;  2E2J E;  2JA8 E;  3FKI E;  3CQZ E;  5C3E E;  4AYB H;  2E2I E;  2E2H E;  4X6A E;  1TWA E;  3GTP E;  4BBS E;  1R9T E;  4A3K E;  1I6H E;  4A3D E;  5M5X E;  1Y1W E;  4BY7 E;  1WCM E;  3K7A E;  3M4O E;  3H3V F;  4A3L E;  3S1M E;  2JA7 E;  4A3B E;  3S14 E;  2R7Z E;  4Y7N E;  4QIW H;  4A3G E;  3PO2 E;  4C3I E;  3GTO E;  1I3Q E;  5FJ8 E;  3S2H E;  3GTG E;  4A93 E;  5C44 E;  2B63 E;  5M5Y E;  4A3J E;  2NVY E;  3S1N E;  4Y52 E;  5C4J E;  3GTK E;  3GTL E;  1K83 E;  4A3F E;  1Y1V E;  2R92 E;  2NVT E;  1TWC E;  3HOZ E;  2WAQ H;  4BBR E;  1TWF E;  3S17 E;  3S1Q E;  2VUM E;  3I4N E;  3PO3 E;  1DZF A;  5FLM E;  2WB1 H;  3S15 E;  4C3H E;  2JA6 E;  2NVX E;  5C4X E;  1TWG E;  5IP7 E;  3HOY E;  3S1R E;  5IYC E;  3HOX E;  3S16 E;  1SFO E;  3GTM E;  3I4M E;  3HOU E;  2R93 E;  4A3I E;  3RZO E;  4BY1 E;  3GTJ E;  5IYB E;  2NVQ E;  3H0G E;  4A3C E;  1EIK A;  3M3Y E;  5IYD E;  3HKZ H;  5IP9 E;  4A3M E;  4C3J E;  3GTQ E;  2YU9 E;  2PMZ H;  3S2D E;  5M5W E;  3HOW E;  2Y0S H;  1TWH E;  5M3F E;  3HOV E;  2JA5 E;  3RZD E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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