3FKIF

12-subunit rna polymerase ii refined with zn-sad data
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
87
structure length
87
Chain Sequence
LKEKAIPKDQRATTPYMTKYERARILGTRALQISMNAPVFVDLEGETDPLRIAMKELAEKKIPLVIRRYLPDGSFEDWSVEELIVDL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the 12-Subunit RNA Polymerase II Refined with the Aid of Anomalous Diffraction Data
pubmed doi rcsb
molecule tags Transcription
molecule keywords DNA-directed RNA polymerase II subunit RPB1
total genus 23
structure length 87
sequence length 87
ec nomenclature
pdb deposition date 2008-12-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
F PF01192 RNA_pol_Rpb6 RNA polymerase Rpb6
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.940.10 Alpha Beta Alpha-Beta Complex Eukaryotic RPB6 RNA polymerase subunit Eukaryotic RPB6 RNA polymerase subunit 3fkiF00
3CQZF 5E18E 3GTGF 1I3QF 1TWHF 1ZYRE 4MEYE 4OINE 3GTQF 2JA7F 4ZH4E 4A93F 4AYBK 4OIOE 4C2MF 3GTJF 4A3KF 4KN4E 4MQ9E 3S2DF 3GTLF 1YNNK 5TMFE 4LK1E 4BY1F 5M5WF 3GTMF 4OIQE 2R93F 4XLPE 5IYDF 1IW7E 3GTOF 3EQLE 4OIPE 5C3EF 1TWFF 4MEXE 2YU9F 3I4MF 3HKZK 2B63F 4XSZE 2JA6F 1SMYE 4C3HF 4C3JF 1K83F 2CW0E 5IYBF 1HQME 5D4EE 3S1MF 3DXJE 4OIRE 2NVQF 4G7ZE 2PPBE 3GTPF 3RZOF 2O5IE 2A6EE 3S17F 5D4CE 2A68E 2NVYF 4C3IF 3H0GF 2JA8F 1QKLA 2O5JE 3S1NF 3M3YF 4LJZE 3S1QF 4LK0E 4G7OE 3FKIF 5IYCF 2VUMF 4A3BF 5M5XF 4Y52F 4A3JF 3HOXF 5IP7F 3S15F 3HOVF 3I4NF 4Y7NF 5C44F 5M3MF 4BXXF 5C4JF 5D4DE 2NVTF 3HOUF 2PMZK 4YFKE 4A3MF 4YG2E 2Y0SI 2WB1I 4XSXE 2E2IF 1I6HF 3S2HF 3PO3F 5M3FF 2E2HF 3H3VG 4BBSF 4LLGE 3PO2F 5FLMF 3S16F 4JK1E 3M4OF 4GZYE 1I6VE 4A3DF 4A3GF 1Y1VF 5M5YF 1Y1WF 3S1RF 4A3CF 2E2JF 1TWAF 1YNJK 2A69E 5E17E 4BY7F 2BE5E 1I50F 1TWCF 4BBRF 4A3LF 2R92F 4Q4ZE 4XLNE 3WODE 4A3EF 2R7ZF 5BYHE 1R9TF 4KN7E 5IP9F 1WCMF 4Q5SE 2JA5F 4G7HE 1SFOF 4X6AF 2NVXF 3HOZF 3RZDF 4KMUE 3HOWF 3S14F 5C4XF 1TWGF 4A3IF 5IPLE 4YFXE 2WAQK 3K7AF 4A3FF 3HOYF 4YFNE 2A6HE 3GTKF 5FJ8F 5TMCE
chains in the Genus database with same CATH superfamily
3CQZF 5E18E 3GTGF 1I3QF 1TWHF 1ZYRE 4MEYE 4OINE 3GTQF 4A3LE 2JA7F 4ZH4E 4A93F 4AYBK 4OIOE 4A3EE 2R7ZE 4C2MF 3GTJF 4A3KF 3HKZH 5IP9E 5M3FE 4KN4E 4MQ9E 2JA5E 3PO2E 1SFOE 2NVXE 3S2DF 3GTLF 3HOWE 1YNNK 5TMFE 3S14E 3M4OE 4LK1E 1TWGE 4BY1F 5M5WF 3GTMF 4AYBH 4A3IE 4OIQE 3K7AE 2R93F 4A3FE 4XLPE 5IYDF 1IW7E 3GTOF 5FJ8E 3GTKE 3S1RE 3EQLE 3CQZE 2E2JE 1TWHE 1TWAE 4OIPE 5C3EF 1TWFF 4MEXE 2YU9F 2JA7E 3I4MF 3HKZK 2B63F 4A93E 4XSZE 2JA6F 1SMYE 3GTJE 1I50E 4C3HF 4C3JF 1K83F 2CW0E 4BBRE 5IYBF 2R92E 1HQME 3GTLE 5D4EE 3S1MF 3GTME 3DXJE 1R9TE 4OIRE 2NVQF 1WCME 4G7ZE 2R93E 2PPBE 3GTPF 3RZOF 2O5IE 4X6AE 3HOZE 3RZDE 2A6EE 3S17F 5D4CE 3I4NE 2A68E 2NVYF 4C3IF 5C4XE 2KRXA 2PMZH 3H0GF 1TWFE 2JA8F 1QKLA 2O5JE 3HOYE 3S1NF 2JA6E 4LJZE 3M3YF 4C3JE 3S1QF 4LK0E 1K83E 4G7OE 3FKIF 5IYCF 3GTGE 3GTQE 1I3QE 2VUMF 4A3BF 5M5XF 4Y52F 4A3JF 4C2ME 3HOXF 4A3KE 5IP7F 3S15F 3HOVF 3I4NF 4Y7NF 5C44F 5M3MF 3GTPE 3RZOE 4BXXF 5C4JF 5D4DE 2NVTF 3HOUF 3S2DE 2PMZK 1EIKA 4YFKE 4A3MF 3S17E 4YG2E 2NVYE 4C3IE 5M5WE 2Y0SI 4BY1E 2WB1I 4XSXE 2E2IF 1I6HF 2JA8E 3H3VF 3S2HF 5M3FF 3PO3F 2WB1H 2E2HF 3H3VG 3M3YE 4BBSF 4LLGE 5IYDE 3GTOE 3PO2F 5FLMF 3FKIE 3S16F 2VUME 4JK1E 5C3EE 5M5XE 2YU9E 3M4OF 4A3JE 3I4ME 4Y52E 2B63E 1DZFA 3HOXE 4C3HE 4GZYE 1I6VE 4A3DF 3S15E 5IYBE 1Y1VF 5M5YF 4Y7NE 5C44E 5M3ME 3S1RF 1Y1WF 4A3GF 5C4JE 2NVTE 4A3CF 2E2JF 3HOUE 1TWAF 4A3ME 1YNJK 3S1ME 2A69E 5E17E 4BY7F 2NVQE 2BE5E 2E2IE 1I6HE 3S2HE 3PO3E 1I50F 2WAQH 1TWCF 2E2HE 4BBSE 4BBRF 4A3LF 5FLME 2R92F 4Q4ZE 4XLNE 3WODE 3S16E 3H0GE 4A3EF 2R7ZF 5BYHE 1R9TF 4KN7E 5IP9F 1WCMF 3S1NE 4QIWK 4Q5SE 2JA5F 3S1QE 4G7HE 1SFOF 4A3DE 4X6AF 2NVXF 3HOZF 5IYCE 1Y1VE 5M5YE 3RZDF 1Y1WE 4A3GE 4KMUE 3HOWF 3S14F 4A3BE 4A3CE 5C4XF 1TWGF 4A3IF 5IPLE 4YFXE 2WAQK 3K7AF 5IP7E 4A3FF 3HOYF 4BY7E 2Y0SH 4YFNE 2A6HE 3HOVE 3GTKF 4QIWH 5FJ8F 1TWCE 4BXXE 5TMCE
chains in the Genus database with same CATH topology
3CQZF 5E18E 3GTGF 1I3QF 1TWHF 1ZYRE 4MEYE 4OINE 3GTQF 2JA7F 4ZH4E 4A93F 4AYBK 4OIOE 4C2MF 3GTJF 4A3KF 4KN4E 4MQ9E 3S2DF 3GTLF 1YNNK 5TMFE 4LK1E 4BY1F 5M5WF 3GTMF 4OIQE 2R93F 4XLPE 5IYDF 1IW7E 3GTOF 3EQLE 4OIPE 5C3EF 1TWFF 4MEXE 2YU9F 3I4MF 3HKZK 2B63F 4XSZE 2JA6F 1SMYE 4C3HF 4C3JF 1K83F 2CW0E 5IYBF 1HQME 5D4EE 3S1MF 3DXJE 4OIRE 2NVQF 4G7ZE 2PPBE 3GTPF 3RZOF 2O5IE 2A6EE 3S17F 5D4CE 2A68E 2NVYF 4C3IF 2KRXA 3H0GF 2JA8F 1QKLA 2O5JE 3S1NF 3M3YF 4LJZE 3S1QF 4LK0E 4G7OE 3FKIF 5IYCF 2VUMF 4A3BF 5M5XF 4Y52F 4A3JF 3HOXF 5IP7F 3S15F 3HOVF 3I4NF 4Y7NF 5C44F 5M3MF 4BXXF 5C4JF 5D4DE 2NVTF 3HOUF 2PMZK 4YFKE 4A3MF 4YG2E 2Y0SI 2WB1I 4XSXE 2E2IF 1I6HF 3S2HF 3PO3F 5M3FF 2E2HF 3H3VG 4BBSF 4LLGE 3PO2F 5FLMF 3S16F 4JK1E 3M4OF 4GZYE 1I6VE 4A3DF 4A3GF 1Y1VF 5M5YF 1Y1WF 3S1RF 4A3CF 2E2JF 1TWAF 1YNJK 2A69E 5E17E 4BY7F 2BE5E 1I50F 1TWCF 4BBRF 4A3LF 2R92F 4Q4ZE 4XLNE 3WODE 4A3EF 2R7ZF 5BYHE 1R9TF 4KN7E 5IP9F 1WCMF 4QIWK 4Q5SE 2JA5F 4G7HE 1SFOF 4X6AF 2NVXF 3HOZF 3RZDF 4KMUE 3HOWF 3S14F 5C4XF 1TWGF 4A3IF 5IPLE 4YFXE 2WAQK 3K7AF 4A3FF 3HOYF 4YFNE 2A6HE 3GTKF 5FJ8F 5TMCE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CQZ F;  5E18 E;  3GTG F;  1I3Q F;  1TWH F;  1ZYR E;  4MEY E;  4OIN E;  3GTQ F;  2JA7 F;  4ZH4 E;  4A93 F;  4AYB K;  4OIO E;  4C2M F;  3GTJ F;  4A3K F;  4KN4 E;  4MQ9 E;  3S2D F;  3GTL F;  1YNN K;  5TMF E;  4LK1 E;  4BY1 F;  5M5W F;  3GTM F;  4OIQ E;  2R93 F;  4XLP E;  5IYD F;  1IW7 E;  3GTO F;  3EQL E;  4OIP E;  5C3E F;  1TWF F;  4MEX E;  2YU9 F;  3I4M F;  3HKZ K;  2B63 F;  4XSZ E;  2JA6 F;  1SMY E;  4C3H F;  4C3J F;  1K83 F;  2CW0 E;  5IYB F;  1HQM E;  5D4E E;  3S1M F;  3DXJ E;  4OIR E;  2NVQ F;  4G7Z E;  2PPB E;  3GTP F;  3RZO F;  2O5I E;  2A6E E;  3S17 F;  5D4C E;  2A68 E;  2NVY F;  4C3I F;  3H0G F;  2JA8 F;  1QKL A;  2O5J E;  3S1N F;  3M3Y F;  4LJZ E;  3S1Q F;  4LK0 E;  4G7O E;  3FKI F;  5IYC F;  2VUM F;  4A3B F;  5M5X F;  4Y52 F;  4A3J F;  3HOX F;  5IP7 F;  3S15 F;  3HOV F;  3I4N F;  4Y7N F;  5C44 F;  5M3M F;  4BXX F;  5C4J F;  5D4D E;  2NVT F;  3HOU F;  2PMZ K;  4YFK E;  4A3M F;  4YG2 E;  2Y0S I;  2WB1 I;  4XSX E;  2E2I F;  1I6H F;  3S2H F;  3PO3 F;  5M3F F;  2E2H F;  3H3V G;  4BBS F;  4LLG E;  3PO2 F;  5FLM F;  3S16 F;  4JK1 E;  3M4O F;  4GZY E;  1I6V E;  4A3D F;  4A3G F;  1Y1V F;  5M5Y F;  1Y1W F;  3S1R F;  4A3C F;  2E2J F;  1TWA F;  1YNJ K;  2A69 E;  5E17 E;  4BY7 F;  2BE5 E;  1I50 F;  1TWC F;  4BBR F;  4A3L F;  2R92 F;  4Q4Z E;  4XLN E;  3WOD E;  4A3E F;  2R7Z F;  5BYH E;  1R9T F;  4KN7 E;  5IP9 F;  1WCM F;  4Q5S E;  2JA5 F;  4G7H E;  1SFO F;  4X6A F;  2NVX F;  3HOZ F;  3RZD F;  4KMU E;  3HOW F;  3S14 F;  5C4X F;  1TWG F;  4A3I F;  5IPL E;  4YFX E;  2WAQ K;  3K7A F;  4A3F F;  3HOY F;  4YFN E;  2A6H E;  3GTK F;  5FJ8 F;  5TMC E; 
#chains in the Genus database with same CATH topology
 3CQZ F;  5E18 E;  3GTG F;  1I3Q F;  1TWH F;  1ZYR E;  4MEY E;  4OIN E;  3GTQ F;  4A3L E;  2JA7 F;  4ZH4 E;  4A93 F;  4AYB K;  4OIO E;  4A3E E;  2R7Z E;  4C2M F;  3GTJ F;  4A3K F;  3HKZ H;  5IP9 E;  5M3F E;  4KN4 E;  4MQ9 E;  2JA5 E;  3PO2 E;  1SFO E;  2NVX E;  3S2D F;  3GTL F;  3HOW E;  1YNN K;  5TMF E;  3S14 E;  3M4O E;  4LK1 E;  1TWG E;  4BY1 F;  5M5W F;  3GTM F;  4AYB H;  4A3I E;  4OIQ E;  3K7A E;  2R93 F;  4A3F E;  4XLP E;  5IYD F;  1IW7 E;  3GTO F;  5FJ8 E;  3GTK E;  3S1R E;  3EQL E;  3CQZ E;  2E2J E;  1TWH E;  1TWA E;  4OIP E;  5C3E F;  1TWF F;  4MEX E;  2YU9 F;  2JA7 E;  3I4M F;  3HKZ K;  2B63 F;  4A93 E;  4XSZ E;  2JA6 F;  1SMY E;  3GTJ E;  1I50 E;  4C3H F;  4C3J F;  1K83 F;  2CW0 E;  4BBR E;  5IYB F;  2R92 E;  1HQM E;  3GTL E;  5D4E E;  3S1M F;  3GTM E;  3DXJ E;  1R9T E;  4OIR E;  2NVQ F;  1WCM E;  4G7Z E;  2R93 E;  2PPB E;  3GTP F;  3RZO F;  2O5I E;  4X6A E;  3HOZ E;  3RZD E;  2A6E E;  3S17 F;  5D4C E;  3I4N E;  2A68 E;  2NVY F;  4C3I F;  5C4X E;  2KRX A;  2PMZ H;  3H0G F;  1TWF E;  2JA8 F;  1QKL A;  2O5J E;  3HOY E;  3S1N F;  2JA6 E;  4LJZ E;  3M3Y F;  4C3J E;  3S1Q F;  4LK0 E;  1K83 E;  4G7O E;  3FKI F;  5IYC F;  3GTG E;  3GTQ E;  1I3Q E;  2VUM F;  4A3B F;  5M5X F;  4Y52 F;  4A3J F;  4C2M E;  3HOX F;  4A3K E;  5IP7 F;  3S15 F;  3HOV F;  3I4N F;  4Y7N F;  5C44 F;  5M3M F;  3GTP E;  3RZO E;  4BXX F;  5C4J F;  5D4D E;  2NVT F;  3HOU F;  3S2D E;  2PMZ K;  1EIK A;  4YFK E;  4A3M F;  3S17 E;  4YG2 E;  2NVY E;  4C3I E;  5M5W E;  2Y0S I;  4BY1 E;  2WB1 I;  4XSX E;  2E2I F;  1I6H F;  2JA8 E;  3H3V F;  3S2H F;  5M3F F;  3PO3 F;  2WB1 H;  2E2H F;  3H3V G;  3M3Y E;  4BBS F;  4LLG E;  5IYD E;  3GTO E;  3PO2 F;  5FLM F;  3FKI E;  3S16 F;  2VUM E;  4JK1 E;  5C3E E;  5M5X E;  2YU9 E;  3M4O F;  4A3J E;  3I4M E;  4Y52 E;  2B63 E;  1DZF A;  3HOX E;  4C3H E;  4GZY E;  1I6V E;  4A3D F;  3S15 E;  5IYB E;  1Y1V F;  5M5Y F;  4Y7N E;  5C44 E;  5M3M E;  3S1R F;  1Y1W F;  4A3G F;  5C4J E;  2NVT E;  4A3C F;  2E2J F;  3HOU E;  1TWA F;  4A3M E;  1YNJ K;  3S1M E;  2A69 E;  5E17 E;  4BY7 F;  2NVQ E;  2BE5 E;  2E2I E;  1I6H E;  3S2H E;  3PO3 E;  1I50 F;  2WAQ H;  1TWC F;  2E2H E;  4BBS E;  4BBR F;  4A3L F;  5FLM E;  2R92 F;  4Q4Z E;  4XLN E;  3WOD E;  3S16 E;  3H0G E;  4A3E F;  2R7Z F;  5BYH E;  1R9T F;  4KN7 E;  5IP9 F;  1WCM F;  3S1N E;  4QIW K;  4Q5S E;  2JA5 F;  3S1Q E;  4G7H E;  1SFO F;  4A3D E;  4X6A F;  2NVX F;  3HOZ F;  5IYC E;  1Y1V E;  5M5Y E;  3RZD F;  1Y1W E;  4A3G E;  4KMU E;  3HOW F;  3S14 F;  4A3B E;  4A3C E;  5C4X F;  1TWG F;  4A3I F;  5IPL E;  4YFX E;  2WAQ K;  3K7A F;  5IP7 E;  4A3F F;  3HOY F;  4BY7 E;  2Y0S H;  4YFN E;  2A6H E;  3HOV E;  3GTK F;  4QIW H;  5FJ8 F;  1TWC E;  4BXX E;  5TMC E; 
#chains in the Genus database with same CATH homology
 3CQZ F;  5E18 E;  3GTG F;  1I3Q F;  1TWH F;  1ZYR E;  4MEY E;  4OIN E;  3GTQ F;  2JA7 F;  4ZH4 E;  4A93 F;  4AYB K;  4OIO E;  4C2M F;  3GTJ F;  4A3K F;  4KN4 E;  4MQ9 E;  3S2D F;  3GTL F;  1YNN K;  5TMF E;  4LK1 E;  4BY1 F;  5M5W F;  3GTM F;  4OIQ E;  2R93 F;  4XLP E;  5IYD F;  1IW7 E;  3GTO F;  3EQL E;  4OIP E;  5C3E F;  1TWF F;  4MEX E;  2YU9 F;  3I4M F;  3HKZ K;  2B63 F;  4XSZ E;  2JA6 F;  1SMY E;  4C3H F;  4C3J F;  1K83 F;  2CW0 E;  5IYB F;  1HQM E;  5D4E E;  3S1M F;  3DXJ E;  4OIR E;  2NVQ F;  4G7Z E;  2PPB E;  3GTP F;  3RZO F;  2O5I E;  2A6E E;  3S17 F;  5D4C E;  2A68 E;  2NVY F;  4C3I F;  2KRX A;  3H0G F;  2JA8 F;  1QKL A;  2O5J E;  3S1N F;  3M3Y F;  4LJZ E;  3S1Q F;  4LK0 E;  4G7O E;  3FKI F;  5IYC F;  2VUM F;  4A3B F;  5M5X F;  4Y52 F;  4A3J F;  3HOX F;  5IP7 F;  3S15 F;  3HOV F;  3I4N F;  4Y7N F;  5C44 F;  5M3M F;  4BXX F;  5C4J F;  5D4D E;  2NVT F;  3HOU F;  2PMZ K;  4YFK E;  4A3M F;  4YG2 E;  2Y0S I;  2WB1 I;  4XSX E;  2E2I F;  1I6H F;  3S2H F;  3PO3 F;  5M3F F;  2E2H F;  3H3V G;  4BBS F;  4LLG E;  3PO2 F;  5FLM F;  3S16 F;  4JK1 E;  3M4O F;  4GZY E;  1I6V E;  4A3D F;  4A3G F;  1Y1V F;  5M5Y F;  1Y1W F;  3S1R F;  4A3C F;  2E2J F;  1TWA F;  1YNJ K;  2A69 E;  5E17 E;  4BY7 F;  2BE5 E;  1I50 F;  1TWC F;  4BBR F;  4A3L F;  2R92 F;  4Q4Z E;  4XLN E;  3WOD E;  4A3E F;  2R7Z F;  5BYH E;  1R9T F;  4KN7 E;  5IP9 F;  1WCM F;  4QIW K;  4Q5S E;  2JA5 F;  4G7H E;  1SFO F;  4X6A F;  2NVX F;  3HOZ F;  3RZD F;  4KMU E;  3HOW F;  3S14 F;  5C4X F;  1TWG F;  4A3I F;  5IPL E;  4YFX E;  2WAQ K;  3K7A F;  4A3F F;  3HOY F;  4YFN E;  2A6H E;  3GTK F;  5FJ8 F;  5TMC E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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